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Sweet Chemistry O3 Barrier Repairing Hydra-Serum Versus DRMTLGY Vitamin C E + F

Serum
Serum
American Brand United States
American Brand United States

Updated on July 02, 2025

Overview

What they are

These products are both cruelty-free and reef safe serums. They have a total of 10 ingredients in common

Cool Features

They both contain ceramides, hyaluronic acid, peptides, Vitamin C and Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates

What's Inside

They both contain oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
O3 Barrier Repairing Hydra-Serum

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Hydrolyzed Cow Bone Extract

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Laminaria Saccharina Extract

Skin Protecting

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Rosa Rubiginosa Seed Oil

Emollient
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Vaccinium Macrocarpon Fruit Extract

Astringent

Vaccinium Myrtillus Fruit Extract

Skin Conditioning

Rubus Fruticosus Fruit Extract

Astringent

Rubus Idaeus Fruit Extract

Astringent

Sambucus Nigra Fruit Extract

Astringent

Pyrus Malus Fruit Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Euterpe Oleracea Fruit Extract

Helps reduce irritation Icon

Emblica Officinalis Fruit Extract

Skin Conditioning

Palmitoyl Hexapeptide-52

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Palmitoyl Tetrapeptide-50

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Heptapeptide-15

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Palmitoyl Heptapeptide-18

Skin Conditioning
Peptide Icon

Palmitoyl Pentapeptide-4

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Copper Palmitoyl Heptapeptide-14

Skin Conditioning
Peptide Icon

Copper Lysinate/Prolinate

Skin Conditioning

Lactic Acid/Glycolic Acid Copolymer

Skin Conditioning

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Phytosphingosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Colloidal Oatmeal

Absorbent
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Skin Texture Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Scar Healing Icon

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Scar Healing Icon

Linolenic Acid

Cleansing
Fragrance IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconNot safe for Fungal Acne Icon

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Sodium PCA

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Sodium Lactate

Buffering

PCA

Humectant
Helps hydrate Dry Skin Icon

Pentylene Glycol

Skin Conditioning

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Aspartic Acid

Masking
Helps hydrate Dry Skin Icon

Glycine

Buffering
Helps hydrate Dry Skin Icon

Alanine

Masking

Serine

Masking
Helps hydrate Dry Skin Icon

Valine

Masking

Histidine

Humectant
Helps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Phenylalanine

Masking
Helps hydrate Dry Skin IconGood for Scar Healing Icon

Isoleucine

Skin Conditioning

Proline

Skin Conditioning

Threonine

Helps hydrate Dry Skin Icon

Thioctic Acid

Antioxidant
Antioxidant IconGood for Scar Healing Icon

Ubiquinone

Antioxidant
Antioxidant IconHelps with Anti-Aging IconGood for Dark Spots Icon

Resveratrol

Antioxidant
Antioxidant IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Dark Spots Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Bisabolol

Masking
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

C12-15 Alkyl Benzoate

Antimicrobial

Methylglucoside Phosphate

Skin Conditioning

Biosaccharide Gum-1

Skin Conditioning
Helps hydrate Dry Skin Icon

Myristyl Glucoside

Cleansing

Lauryl Glucoside

Cleansing

Polyglyceryl-6 Laurate

Emulsifying
Not safe for Fungal Acne Icon

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Hexylene Glycol

Emulsifying
0-2 / 0-1

Xanthan Gum

Emulsifying

Polyvinyl Alcohol

Trisodium Ethylenediamine Disuccinate

Phenoxyethanol

Preservative
Preservative Icon

Ethylhexylglycerin

Skin Conditioning

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Water, Glycerin, Niacinamide, Caprylic/Capric Triglyceride, Hydrolyzed Cow Bone Extract, Ceramide NP, Tetrahexyldecyl Ascorbate, Laminaria Saccharina Extract, Cholesterol, Propanediol, Rosa Rubiginosa Seed Oil, Camellia Sinensis Leaf Extract, Vaccinium Macrocarpon Fruit Extract, Vaccinium Myrtillus Fruit Extract, Rubus Fruticosus Fruit Extract, Rubus Idaeus Fruit Extract, Sambucus Nigra Fruit Extract, Pyrus Malus Fruit Extract, Euterpe Oleracea Fruit Extract, Emblica Officinalis Fruit Extract, Palmitoyl Hexapeptide-52, Palmitoyl Tetrapeptide-50, Heptapeptide-15, Palmitoyl Heptapeptide-18, Palmitoyl Pentapeptide-4, Copper Palmitoyl Heptapeptide-14, Copper Lysinate/Prolinate, Lactic Acid/Glycolic Acid Copolymer, Ceramide AP, Phytosphingosine, Colloidal Oatmeal, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Beta-Glucan, Linolenic Acid, Linoleic Acid, Panthenol, Sodium PCA, Sodium Lactate, PCA, Pentylene Glycol, Arginine, Aspartic Acid, Glycine, Alanine, Serine, Valine, Histidine, Phenylalanine, Isoleucine, Proline, Threonine, Thioctic Acid, Ubiquinone, Resveratrol, Tocopheryl Acetate, Bisabolol, Allantoin, C12-15 Alkyl Benzoate, Methylglucoside Phosphate, Biosaccharide Gum-1, Myristyl Glucoside, Lauryl Glucoside, Polyglyceryl-6 Laurate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hexylene Glycol, Xanthan Gum, Polyvinyl Alcohol, Trisodium Ethylenediamine Disuccinate, Phenoxyethanol, Ethylhexylglycerin, Caprylyl Glycol

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning

Ceramide AP is a type of Ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. Having a strong skin barrier leads to more firm and hydrated skin.

They are known for their ability to hold water and thus are a great ingredient for dry skin. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here:
Ceramide NP
Ceramide EOP

Learn more about Ceramide AP
Skin Conditioning

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here:
Ceramide AP
Ceramide EOP

Learn more about Ceramide NP
Emollient, Emulsifying, Skin Conditioning

Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.

Our skin naturally contains cholesterol in the outermost layer. Besides cholesterol, it also contains ceramides and fatty acids. Cholesterol makes up about 1/4 of your skin's outer layer and barrier. Your skin barrier is responsible for keeping allergens and microbes out. Having a healthy skin barrier is also responsible for keeping your skin firm and plump.

Our bodies use cholestrol to create vitamin D, steroid hormones, and more.

Learn more about Cholesterol
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Skin Conditioning

Phytosphingosine is a phospholipid naturally found in our skin as a building block for ceramides.. It helps moisturize, soothe, and protect skin.

Phytosphingosine contributes to your skin's natural moisturizing factor (NMF). The NMF is responsible for hydration, a strong barrier, and plasticity. Our NMF decreases with age. Increasing NMF leads to more healthy and hydrated skin.

Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.

Fun fact: Phytosphingosine is abundant in plants and fungi.

More ingredients that help boost collagen in skin:

Learn more about Phytosphingosine
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

When to use

100 Routines
83% use in am
17% use in pm
97% use every day
When to use See routines that use it ->

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