Updated on September 14, 2023
Overview
What they are
These products are both reef safe serums. They have a total of 9 ingredients in common
Cool Features
They both contain ceramides, peptides, Vitamin C and Vitamin E
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, parabens or sulfates
What's Inside
They both contain fragrances
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
SkinBetter Science Alto Defense Serum 64 ingredients
Paula's Choice Resist Super Antioxidant Serum 25 ingredients
At a glance
Click on any of the items below to learn more
SkinBetter Science Alto Defense Serum 64 ingredients
Paula's Choice Resist Super Antioxidant Serum 25 ingredients
Notable Ingredients
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Benefits
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Concerns
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Notable Ingredients
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Benefits
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Ingredients Side-by-side
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
3 Concerns
Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.
Chlorogenic acid refers to a group of related acids including caffeic acid, ferulic acid and p-coumaric acid.
Dimethyl Isosorbide is a solvent and helps deliver actives into your skin. It is created from sorbitol.
Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.
Antioxidant 4 Benefits Not safe for Fungal Acne
Ascorbyl Tetraisopalmitate is a version of ascorbic acid, or pure Vitamin C.
5 Benefits
Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.
Vitis Vinifera Seed Extract comes from the grape vine. Grape seeds are a byproduct of creating grape juice or wine.
Theobroma Cacao Seed Extract comes from the Theobroma cacoa, or Cacao tree. Cacao trees are native to tropical landscapes.
Curcuma Longa Root Extract is from the spice, turmeric. Besides being a healthy and delicious spice, turmeric also has plenty of skincare benefits. It has anti-inflammatory, antioxidant, and anti-microbial properties.
This extract comes from the Cabbage Palm, AKA the Açaí berry! It has skin soothing, antioxidant, and anti-aging properties.
Superoxide Dismutase is found in all living cells. This ingredient is AKA as 'SOD'.
Helps with Anti-Aging
Ubiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.
3 Concerns
Linoleic Acid is Vitamin F and a fatty acid. It is an emollient and helps thicken texture. Linoleic acid helps with hydrating skin and nourishing the skin's barrier. The top layer of skin, or epidermis, contains high amounts of linoleic acid naturally.
Not safe for Fungal Acne
Linolenic Acid is a fatty acid. Our bodies need to consume this to use it. Linolenic Acid helps condition and restore skin. It is also used to treat inflammation and hyperpigmentation.
Bisabolol is pimarily used to add fragrance to a product. However, it is also famous for helping soothe skin.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.
Phytosphingosine is a phospholipid naturally found in our skin. It helps moisturize, soothe, and protect skin.
Jojoba Esters is a wax created from Jojoba oil. It is an emollient and film-forming ingredient. In bead form, it is an exfoliator.
Sodium PCA is the sodium salt of pyroglutamic acid and is naturally occurring on human skin.
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Helianthus Annuus Seed Wax is created from the common sunflower.
Acacia Decurrens Flower Wax isn't fungal acne safe.
Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
Diisostearyl Malate is an emollient and most often used in lip products. It comes from isostearyl alcohol, a fatty acid, and malic acid, an AHA.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Steareth-2 is a waxy compound used to emulsify ingredients. It is created from polyethylene glycol and stearyl alcohol.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
4 Benefits 2 Concerns
Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Water, Butylene Glycol, Propanediol, Ethylhexyl Olivate, Cetearyl Alcohol, Chlorogenic Acids, Hydrolyzed Sodium Hyaluronate, Lauryl Lactate, Dimethyl Isosorbide, Glycyrrhiza Glabra Root Extract, Ascorbyl Tetraisopalmitate, Ergothioneine, Benzylidene Dimethoxydimethylindanone, Arabidopsis Thaliana Extract, Carnosine, Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Extract, Theobroma Cacao Seed Extract, Curcuma Longa Root Extract, Olea Europaea Fruit Extract, Euterpe Oleracea Fruit Extract, Trifluoroacetyl Tripeptide-2, Buddleja Officinalis Flower Extract, Coffea Arabica Leaf Cell Extract, Crocus Sativus Leaf Cell Culture Extract, Superoxide Dismutase, Ubiquinone, Zingiber Officinale Root Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Linoleic Acid, Linolenic Acid, Sea Whip Extract, Bisabolol, Tocopherol, Tocopheryl Acetate, Cholesterol, Phytosphingosine, Jojoba Esters, Sodium PCA, Pentylene Glycol, Methyl Gluceth-20, Glycerin, Helianthus Annuus Seed Wax, Acacia Decurrens Flower Wax, Lecithin, Sodium Lauroyl Lactylate, Dicetyl Phosphate, Propanediol Dicaprylate/Caprate, Polyglycerin-3, Ceteth-20 Phosphate, Diisostearyl Malate, Xanthan Gum, Steareth-2, Acacia Senegal Gum, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dextran, Sodium Hydroxide, Citric Acid, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol
Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.
Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.
Antioxidant 5 Benefits
Tetrahexyldecyl Ascorbate is a form of Vitamin C.
Not safe for Fungal Acne
Palmitoyl Tripeptide-5 isn't fungal acne safe and is a peptide.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Helps with Anti-Aging
Ubiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.
Thioctic Acid is an enzyme and antioxidant. A more common name for this is Alpha Lipoic Acid.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
Antioxidant 5 Benefits
Magnesium Ascorbyl Phosphate (MAP) is a form of Vitamin C and is an antioxidant. It can help to reduce redness, improve skin texture, reduce the effects of aging, reduce the visibility of dark spots, and brighten skin.
Helps with Anti-Aging
Ferulic Acid is a plant based antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. Ferulic Acid can help reduce the formation of fine lines and hyperpigmentation.
Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.
Superoxide Dismutase is found in all living cells. This ingredient is AKA as 'SOD'.
EGCG is most famous for being found in green tea. It is a type of catechin, a potent antioxidant.
Glutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.
Glycine Soja Seed Extract comes from the seed of the wild soybean plant. Wild soybean extract contains fatty acids (linoleic, oleic, linolenic), vitamin E, and antioxidants.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Curcuma Longa Root Extract is from the spice, turmeric. Besides being a healthy and delicious spice, turmeric also has plenty of skincare benefits. It has anti-inflammatory, antioxidant, and anti-microbial properties.
Not safe for Fungal Acne
Elaeis Guineensis Oil comes from the African Palm tree. This tree is native to Western and Southwestern Africa.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Cyclopentasiloxane, Dimethicone, Tetrahexyldecyl Ascorbate, Palmitoyl Tripeptide-5, Ceramide NP, Tocotrienols, Tocopherol, Ubiquinone, Thioctic Acid, Tocopheryl Acetate, Magnesium Ascorbyl Phosphate, Ferulic Acid, Beta-Glucan, Superoxide Dismutase, Epigallocatechin Gallate, Ergothioneine, Glutathione, Xanthophylls, Glycine Soja Seed Extract, Glycerin, Arctostaphylos Uva Ursi Leaf Extract, Lupinus Albus Seed Extract, Curcuma Longa Root Extract, Elaeis Guineensis Oil, Phenoxyethanol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ergothioneine is an antioxidant.
Curcuma Longa Root Extract is from the spice, turmeric. Besides being a healthy and delicious spice, turmeric also has plenty of skincare benefits. It has anti-inflammatory, antioxidant, and anti-microbial properties.
Turmeric contains curcumin, an antioxidant. Antioxidants help neutralize unstable free-radical molecules. Free-radical molecules may damage your skin's cells and DNA. Curcumin may help with anti-aging.
Curcumin also has anti-inflammatory properties. It can help soothe skin and reduce irritation. On top of that, curcumin has been shown to help prevent hyperpigmentation from sun damage.
The anti-microbial property of turmeric can make it effective in treating acne. It has also been shown to help regulate the production of sebum.
Learn more about Curcuma Longa Root ExtractSuperoxide Dismutase is found in all living cells. This ingredient is AKA as 'SOD'.
SOD is a strong antioxidant. It protects living cells against oxidative damage by breaking down radical molecules into regular oxygen and hydrogen peroxide.
Antioxidants help fight free-radical molecules that may damage your skin's DNA. This may help with the signs of aging. Due to its antioxidant property, it is used to help treat chronic inflammation.
In cosmetics, SOD is usually obtained from marine phytoplankton, bovine liver, horseradish, cantaloupe, and certain bacteria.
The three major families of SOD include: Copper/Zinc, Iron/Manganese, and Nickel.
When eating SOD-rich foods, our bodies break it down into amino acids before absorption. Foods that contain SOD include: melons, citrus, spinach, broccoli, kale, almonds, sunflower seeds, and blue-green algae.
Learn more about Superoxide DismutaseUbiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.
Aging and environmental exposure diminishes our skin's natural ubiquinone levels. This is much like our natural collagen and elastin.
The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:
Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.
When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.
Fun fact: ubiquinone is fat-soluble.
Learn more about UbiquinoneCeramide NP is a type of ceramide.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here: Ceramide AP Ceramide EOP
Learn more about Ceramide NPTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ingredient Ratings
Here's what our community thinks of the ingredients in these two products.
When to use
SkinBetter Science Alto Defense Serum 64 ingredients
Paula's Choice Resist Super Antioxidant Serum 25 ingredients
Reviews
Here's what our community thinks
SkinBetter Science Alto Defense Serum 64 ingredients
AideeCantu
Don’t like how it doesn’t spread easily on face
Used daily for three days and it made me itchy
Cut back to every other day and it made my...
Don’t like how it doesn’t spread easily on face
Used daily for three days and it made me itchy
Cut back to every other day and it made my cheeks red and warm; it ended up breaking my skin barrier
