Versus

SkinBetter Science Alto Defense Serum Versus Paula's Choice Resist Super Antioxidant Serum

Serum
Serum
American Brand United States
American Brand United States

Updated on July 17, 2024

Overview

What they are

These products are both reef safe serums. They have a total of 9 ingredients in common

Cool Features

They both contain ceramides, peptides, Vitamin C and Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Ingredients Side-by-side

found in both products
Alto Defense Serum

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Propanediol

Solvent

Ethylhexyl Olivate

Skin Conditioning
Not safe for Fungal Acne Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Chlorogenic Acids

Antioxidant
Antioxidant Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning

Lauryl Lactate

Emollient

Dimethyl Isosorbide

Solvent

Glycyrrhiza Glabra Root Extract

Bleaching
Good for Dark Spots Icon

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Ergothioneine

Antioxidant
Antioxidant Icon

Benzylidene Dimethoxydimethylindanone

Skin Protecting

Arabidopsis Thaliana Extract

Antioxidant
Antioxidant Icon

Carnosine

Skin Conditioning

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Vitis Vinifera Seed Extract

Antimicrobial
Antioxidant Icon

Theobroma Cacao Seed Extract

Antioxidant
Antioxidant Icon

Curcuma Longa Root Extract

Masking
Fragrance Icon

Olea Europaea Fruit Extract

Bleaching

Euterpe Oleracea Fruit Extract

Trifluoroacetyl Tripeptide-2

Skin Conditioning
Peptide Icon

Buddleja Officinalis Flower Extract

UV Filter

Coffea Arabica Leaf Cell Extract

Antioxidant
Antioxidant Icon

Crocus Sativus Leaf Cell Culture Extract

Skin Protecting

Superoxide Dismutase

Antioxidant
Antioxidant IconHelps with Anti-Aging Icon

Ubiquinone

Antioxidant
Antioxidant IconHelps with Anti-Aging IconGood for Dark Spots Icon

Zingiber Officinale Root Extract

Masking

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide EOP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Linolenic Acid

Cleansing
Fragrance IconNot safe for Fungal Acne Icon

Sea Whip Extract

Skin Conditioning

Bisabolol

Masking
Helps reduce irritation Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Phytosphingosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Jojoba Esters

Emollient
Not safe for Fungal Acne Icon

Sodium PCA

Humectant
0 / 0

Pentylene Glycol

Skin Conditioning

Methyl Gluceth-20

Humectant

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Helianthus Annuus Seed Wax

Skin Conditioning
Not safe for Fungal Acne Icon

Acacia Decurrens Flower Wax

Emollient
Not safe for Fungal Acne Icon

Lecithin

Emollient

Sodium Lauroyl Lactylate

Emulsifying

Dicetyl Phosphate

Emulsifying

Propanediol Dicaprylate/Caprate

Emollient

Polyglycerin-3

Humectant

Ceteth-20 Phosphate

Cleansing

Diisostearyl Malate

Emollient

Xanthan Gum

Emulsifying

Steareth-2

Emulsifying
2 / 2

Acacia Senegal Gum

Masking

Carbomer

Emulsion Stabilising
1 / 0

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Dextran

Sodium Hydroxide

Buffering

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Disodium EDTA

Ethylhexylglycerin

Skin Conditioning

Phenoxyethanol

Preservative
Preservative Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Antioxidant, Skin Conditioning

Tetrahexyldecyl Ascorbate (THD) is a stable and oil-soluble form of Vitamin C.

THD is special in that it has the ability to travel deeper into skin than traditional ascorbic acid while maintaining the same skin benefits (double win!).

Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.

Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.

Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.

A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).

While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.

THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!

Read more about other types of Vitamin C:

Learn more about Tetrahexyldecyl Ascorbate
Antioxidant

Ergothioneine is an amino acid found naturally in mushrooms, grains, and meat. It has antioxidant and skin soothing properties.

According to a manufacturer, this amino acid helps with:

  • Maintaining DNA stability and cell reproduction
  • Enhances cellular immunity
  • Skin brightening
  • Anti-aging
  • Skin soothing
Antioxidant, Skin Conditioning

Superoxide Dismutase is found in all living cells. This ingredient is AKA as 'SOD'.

SOD is a strong antioxidant. It protects living cells against oxidative damage by breaking down radical molecules into regular oxygen and hydrogen peroxide.

Antioxidants help fight free-radical molecules that may damage your skin's DNA. This may help with the signs of aging. Due to its antioxidant property, it is used to help treat chronic inflammation.

In cosmetics, SOD is usually obtained from marine phytoplankton, bovine liver, horseradish, cantaloupe, and certain bacteria.

The three major families of SOD include: Copper/Zinc, Iron/Manganese, and Nickel.

When eating SOD-rich foods, our bodies break it down into amino acids before absorption. Foods that contain SOD include: melons, citrus, spinach, broccoli, kale, almonds, sunflower seeds, and blue-green algae.

Learn more about Superoxide Dismutase
Antioxidant, Skin Conditioning

Ubiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.

Aging and environmental exposure diminishes our skin's natural ubiquinone levels. This is much like our natural collagen and elastin.

The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:

Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.

When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.

Fun fact: ubiquinone is fat-soluble.

Learn more about Ubiquinone
Skin Conditioning

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP

Learn more about Ceramide NP
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

When to use

20 Routines
70% use in am
30% use in pm
100% use every day
59 Routines
76% use in am
24% use in pm
85% use every day
When to use See routines that use it ->