Sesderma Mandelac Moisturizing Cream Versus CeraVe Skin Renewing Night Cream to Soften Skin
Updated on April 04, 2025
Overview
Cool Features
They both contain peptides and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
What's Inside
They both contain silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Sesderma Mandelac Moisturizing Cream 57 ingredients
CeraVe Skin Renewing Night Cream to Soften Skin 40 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Sesderma Mandelac Moisturizing Cream 57 ingredients
CeraVe Skin Renewing Night Cream to Soften Skin 40 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningIsohexadecane
EmollientC12-15 Alkyl Benzoate
AntimicrobialLimnanthes Alba Seed Oil
Skin Conditioning
Glycerin
Humectant
Propylene Glycol
Humectant
Cetyl Alcohol
Emollient
Glyceryl Stearate
Emollient
PEG-100 Stearate
Saccharide Isomerate
HumectantAmmonium Acryloyldimethyltaurate/Vp Copolymer
Tocopheryl Acetate
Antioxidant
Aloe Barbadensis Leaf Juice
Skin Conditioning
Sodium PCA
HumectantUrea
Buffering
Mandelic Acid
Antimicrobial
Camellia Sinensis Leaf Extract
Antimicrobial
Glycolic Acid
Buffering
Caprooyl Tetrapeptide-3
Skin Protecting
Retinol
Skin Conditioning
Sodium Lactate
BufferingHydrolyzed Collagen
Emollient
Malus Domestica Fruit Cell Culture Extract
Skin ConditioningAllantoin
Skin Conditioning
Lecithin
EmollientAlcohol
Antimicrobial
Dimethicone
Emollient
Xanthan Gum
EmulsifyingDipropylene Glycol
MaskingPolysorbate 20
Emulsifying
Dextran
Sodium Hydroxide
BufferingDisodium EDTA
Sodium Cholate
Skin ConditioningCitric Acid
Buffering
Tocopherol
Antioxidant
Achillea Millefolium Extract
CleansingChamomilla Recutita Extract
Skin Conditioning
Viscum Album Leaf Extract
SoothingMelissa Officinalis Leaf Oil
Masking
Humulus Lupulus Extract
AntimicrobialFoeniculum Vulgare Fruit Extract
EmollientAscorbyl Palmitate
Antioxidant
Glyceryl Oleate
Emollient
BHT
Antioxidant
BHA
Antioxidant
Phenoxyethanol
Preservative
Ethylparaben
Preservative
Methylparaben
Preservative
Potassium Sorbate
Preservative
Propylparaben
Preservative
Parfum
Masking
Coumarin
Perfuming
Citral
Perfuming
Eugenol
Perfuming
Limonene
Perfuming
Isoeugenol
Perfuming
Water, Isohexadecane, C12-15 Alkyl Benzoate, Limnanthes Alba Seed Oil, Glycerin, Propylene Glycol, Cetyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Saccharide Isomerate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Tocopheryl Acetate, Aloe Barbadensis Leaf Juice, Sodium PCA, Urea, Mandelic Acid, Camellia Sinensis Leaf Extract, Glycolic Acid, Caprooyl Tetrapeptide-3, Retinol, Sodium Lactate, Hydrolyzed Collagen, Malus Domestica Fruit Cell Culture Extract, Allantoin, Lecithin, Alcohol, Dimethicone, Xanthan Gum, Dipropylene Glycol, Polysorbate 20, Dextran, Sodium Hydroxide, Disodium EDTA, Sodium Cholate, Citric Acid, Tocopherol, Achillea Millefolium Extract, Chamomilla Recutita Extract, Viscum Album Leaf Extract, Melissa Officinalis Leaf Oil, Humulus Lupulus Extract, Foeniculum Vulgare Fruit Extract, Ascorbyl Palmitate, Glyceryl Oleate, BHT, BHA, Phenoxyethanol, Ethylparaben, Methylparaben, Potassium Sorbate, Propylparaben, Parfum, Coumarin, Citral, Eugenol, Limonene, Isoeugenol
Water
Skin ConditioningGlycerin
Humectant
Caprylic/Capric Triglyceride
MaskingButyrospermum Parkii Butter
Skin Conditioning
Dimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningCyclopentasiloxane
Emollient
Glyceryl Stearate Se
Emulsifying
Cetyl Alcohol
Emollient
Dimethicone
Emollient
Saccharide Isomerate
HumectantStearic Acid
Cleansing
Palmitic Acid
Emollient
Glycine Soja Sterols
Emollient
Allantoin
Skin Conditioning
Ceramide NP
Skin Conditioning
Ceramide AP
Skin Conditioning
Ceramide EOP
Skin Conditioning
Carbomer
Emulsion StabilisingNiacinamide
Smoothing
Cetearyl Alcohol
Emollient
Behentrimonium Methosulfate
Sodium Hydroxide
BufferingMyristic Acid
Cleansing
Sodium Lauroyl Lactylate
EmulsifyingSodium Benzoate
Masking
Sodium Citrate
BufferingSodium Hyaluronate
Humectant
Cholesterol
Emollient
Phenoxyethanol
Preservative
Tocopherol
Antioxidant
Tripeptide-1
Skin Conditioning
Laureth-9
EmulsifyingCitric Acid
Buffering
Caprooyl Tetrapeptide-3
Skin Protecting
Biosaccharide Gum-1
Skin ConditioningPhytosphingosine
Skin Conditioning
Xanthan Gum
EmulsifyingDextran
Ethylhexylglycerin
Skin ConditioningButylene Glycol
Humectant
Water, Glycerin, Caprylic/Capric Triglyceride, Butyrospermum Parkii Butter, Dimethicone/Vinyl Dimethicone Crosspolymer, Cyclopentasiloxane, Glyceryl Stearate Se, Cetyl Alcohol, Dimethicone, Saccharide Isomerate, Stearic Acid, Palmitic Acid, Glycine Soja Sterols, Allantoin, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Niacinamide, Cetearyl Alcohol, Behentrimonium Methosulfate, Sodium Hydroxide, Myristic Acid, Sodium Lauroyl Lactylate, Sodium Benzoate, Sodium Citrate, Sodium Hyaluronate, Cholesterol, Phenoxyethanol, Tocopherol, Tripeptide-1, Laureth-9, Citric Acid, Caprooyl Tetrapeptide-3, Biosaccharide Gum-1, Phytosphingosine, Xanthan Gum, Dextran, Ethylhexylglycerin, Butylene Glycol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol. The FDA allows products labeled "alcohol-free" to have fatty alcohols.
Learn more about Cetyl AlcoholSaccharide Isomerate comes from sugars found in corn. It is a skin hydrator.
The structure of this ingredient can be altered to be more similar to the carbohydrates found in our skin. This ability to mimic our skin gives it hydrating properties.
Specifically, saccharide Isomerate is a humectant. Humectants draw moisture from the air to our skin.
Research shows Saccharide Isomerate to be an effective moisturizer.
Learn more about Saccharide IsomerateCaprooyl Tetrapeptide-3 is a peptide.
Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.
Some studies have shown this ingredient can promote wound healing with higher concentrations.
Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.
Learn more about AllantoinDimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumDextran is a sugar (polysaccharide) with skin hydrating properties.
Fun fact: Louis Pasteur first discovered this ingredient as a microbial product in wine.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideCitric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Sesderma Mandelac Moisturizing Cream 57 ingredients
CeraVe Skin Renewing Night Cream to Soften Skin 40 ingredients
Reviews
Here's what our community thinks
CeraVe Skin Renewing Night Cream to Soften Skin 40 ingredients
Favorite for buffering or sandwiching retinoids!
When I first started my strong retinoid journey to help deal with my acne I was on the hunt for a thick moisturizer to help act as a buffer to my adapalene gel and to ease me through the retinization process. However I didn’t want anything too occlusive either, so I wanted to avoid petrolatum and oils (not all oils are super occlusive, but I wanted Show more
Simple, very hydrating night time moisturizer. My skin loves this stuff. Bonus points for being affordable
