Updated on September 07, 2023
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 6 ingredients in common
Cool Features
They both contain Vitamin C
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, scar healing, dark spots and better texture
Free From
They both do not contain any oils, parabens or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Paula's Choice 25% Vitamin C + Glutathione Clinical Serum 40 ingredients
Dr. Dennis Gross Skincare C+ Collagen Brighten & Firm Vitamin C Serum 38 ingredients
At a glance
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Paula's Choice 25% Vitamin C + Glutathione Clinical Serum 40 ingredients
Dr. Dennis Gross Skincare C+ Collagen Brighten & Firm Vitamin C Serum 38 ingredients
Notable Ingredients
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Benefits
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Concerns
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Notable Ingredients
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Ingredients Side-by-side
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Antioxidant 5 Benefits
Tetrahexyldecyl Ascorbate is a form of Vitamin C.
Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
C9-12 Alkane is synethically created using alkanes, or paraffins. It is added to products as a solvent. This means its main purpose is to help dissolve ingredients and create even texture.
Antioxidant 6 Benefits
Ascorbyl Glucoside is a stable form of Vitamin C. It is created by combining glucose from starch.
2 Concerns
Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.
Pyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.
Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.
Polyglyceryl-6 Polyricinoleate isn't fungal acne safe.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Oryza Sativa Bran Extract comes from the outer layer of a rice kernel. It is a byproduct of milling rice, or the operation to produce a whole grain rice product.
This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Coco-Caprylate is created from fatty coconut alcohol and caprylic acid.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Glutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.
Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Urea is also called carbamide and is the diamide of carbonic acid. In cosmetics, urea is used to hydrate the skin. It also provides exfoliation in higher concentrations.
Mannitol is a sugar alcohol. It is a humectant and moisturizes the skin. In vitro (not tested on a living organism), mannitol displays antioxidant properties.
Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Sodium PCA is the sodium salt of pyroglutamic acid and is naturally occurring on human skin.
Rosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.
Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.
Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.
Antioxidant 6 Benefits
Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.
Glucose is a simple sugar and is the most important source of energy in all organisms.
Vanilla Planifolia Fruit Extract comes from the vanilla orchid native to central America. It is a skin-soothing ingredient.
Polyquaternium-51 is a polymer salt. It helps hydrate the skin by creating a film on top. This film traps moisture in, keeping your skin soft and hydrated.
Triacetin comes from glycerin and acetic acid. It has antimicrobial properties.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Water, Tetrahexyldecyl Ascorbate, Dimethicone, Glycerin, C9-12 Alkane, Ascorbyl Glucoside, Silica, Pyrus Malus Fruit Extract, Hydrogenated Lecithin, Polyglyceryl-6 Polyricinoleate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Oryza Sativa Bran Extract, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetyl Alcohol, Caprylyl Glycol, Lysine Carboxymethyl Cysteinate, Coco-Caprylate, Tocopherol, Glutathione, Sodium Citrate, Sodium Phytate, Hexylene Glycol, Ethylhexylglycerin, Helianthus Annuus Seed Extract, Urea, Mannitol, Caprylic/Capric Triglyceride, Sodium PCA, Rosmarinus Officinalis Leaf Extract, Polysorbate 60, Sorbitan Isostearate, Trehalose, Ascorbic Acid, Glucose, Vanilla Planifolia Fruit Extract, Polyquaternium-51, Ergothioneine, Triacetin, Phenoxyethanol
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
5 Benefits
You might know this ingredient as Ethyl Ascorbic Acid, a more stable version of ascorbic acid.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
6 Benefits 3 Concerns
Lactic Acid is an AHA that is derived from fermenting lactose, a carbohydrate from milk. It removes the top layer of old and dead skin cells and helps increase cell turnover.
SD Alcohol 40-B is created by denaturing ethanol with tert-Butyl alcohol and denatonium benzoate. It is a solvent and astringent.
Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.
Dimethyl Isosorbide is a solvent and helps deliver actives into your skin. It is created from sorbitol.
Antioxidant 6 Benefits
Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.
Collagen is the most abundant type of structural protein found in your body. In your skin, it is responsible for keeping it firm and youthful.
Superoxide Dismutase is found in all living cells. This ingredient is AKA as 'SOD'.
Glycine is an amino acid that helps build proteins. It is already present in our skin as our bodies produce them naturally.
Helps with Anti-Aging
Ubiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.
Another popular name for this ingredient is Synovea HR. This ingredient is a skin lightener and antioxidant.
This ingredient is a vegetable-derived protein made to mimic hydrolyzed collagen. It is created from soy, or glycine soja.
Antioxidant 4 Benefits Not safe for Fungal Acne
Ascorbyl Tetraisopalmitate is a version of ascorbic acid, or pure Vitamin C.
2 Benefits 2 Concerns
Mandelic Acid helps exfoliate skin. It also contains antioxidant properties.
Curcuma Longa Root Extract is from the spice, turmeric. Besides being a healthy and delicious spice, turmeric also has plenty of skincare benefits. It has anti-inflammatory, antioxidant, and anti-microbial properties.
Helps brighten skin May worsen Rosacea
Phytic Acid is a gentle AHA and antioxidant. The chemical makeup makes it classified as an AHA, such as lactic acid.
4 Benefits 2 Concerns
Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
Tetrasodium EDTA is the salt formed from neutralizing ethylenediamine tetraacetic acid with sodium hydroxide. It is a chelating agent and used to prevent metal ions from binding to other ingredients. This helps keep the product and ingredients stable.
Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Fragrance
T-Butyl Alcohol it is most commonly used as a solvent.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
Polysorbate 80 is a surfactant and emulsifier. It is used to keep ingredients together, and prevent oils and waters from separating.
Fragrance Preservative 6 Concerns
Benzyl Alcohol is most commonly used as a preservative. It also has a subtle, sweet smell. Small amounts of Benzyl Alcohol is not irritating and safe to use in skincare products. Most Benzyl Alcohol is derived from fruits such as apricots.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
Water, Glycerin, 3-O-Ethyl Ascorbic Acid, Niacinamide, Glycereth-7 Triacetate, Lactic Acid, Sd Alcohol 40-B, Hydroxyethylcellulose, Dimethyl Isosorbide, Ascorbic Acid, Collagen Amino Acids, Superoxide Dismutase, Glycine, Carnitine Hcl, Ubiquinone, Hexylresorcinol, Emblica Officinalis Fruit Extract, Hydrolyzed Soy Protein, Ascorbyl Tetraisopalmitate, Isoquercetin, Mandelic Acid, Pueraria Lobata Root Extract, Curcuma Longa Root Extract, Phytic Acid, Citric Acid, Tetrasodium EDTA, Sodium Citrate, Butylene Glycol, Xanthan Gum, Polysorbate 20, T-Butyl Alcohol, Sodium Hydroxide, Polysorbate 80, Denatonium Benzoate, Benzyl Alcohol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumSodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Sodium Citrate helps maintain the pH of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Sodium Citrate is a chelating agent. It neutralizes metal ions from water and prevents them from binding to other ingredients. This ensures the other ingredients will not be altered.
Learn more about Sodium CitrateAscorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.
Not only is vitamin C great for your overall health and immune system, it also has plenty of benefits on your skin.
Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.
Remember: Vitamin C should not replace sunscreen!
Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.
Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.
The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.
Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.
Read more about other types of Vitamin C:
Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.
Learn more about Ascorbic AcidPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ingredient Ratings
Here's what our community thinks of the ingredients in these two products.
When to use
Paula's Choice 25% Vitamin C + Glutathione Clinical Serum 40 ingredients
Dr. Dennis Gross Skincare C+ Collagen Brighten & Firm Vitamin C Serum 38 ingredients
