Versus

Maya Chia The Advance Response Complex Versus Eight Saints Up The Anti

Night Moisturizer
Night Moisturizer
American Brand United States
American Brand United States

Updated on April 01, 2025

Overview

What they are

These products are both cruelty-free and reef safe night moisturizers. They have a total of 21 ingredients in common

Cool Features

They both contain hyaluronic acid, peptides and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any parabens, silicones or sulfates

What's Inside

They both contain fragrances and oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
The Advance Response Complex

Aloe Barbadensis Leaf Juice

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Orbignya Oleifera Seed Oil

Emollient
1 / 0 Oil IconNot safe for Fungal Acne Icon

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Isoamyl Laurate

Emollient
Not safe for Fungal Acne Icon

Isoamyl Cocoate

Can worsen Dry Skin IconNot safe for Fungal Acne Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Coco-Glucoside

Cleansing

Salvia Hispanica Seed Oil

Moisturising
Oil IconNot safe for Fungal Acne Icon

Haematococcus Pluvialis Extract

Antioxidant
Antioxidant Icon

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Caprylic/Capric Triglyceride

Masking

Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76

Skin Conditioning
Peptide Icon

Hexapeptide-11

Skin Conditioning
Peptide Icon

Tripeptide-29

Skin Conditioning
Peptide Icon

Terminalia Chebula Fruit Extract

Skin Conditioning

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Anigozanthos Flavidus Extract

Skin Conditioning

Xylitylglucoside

Humectant

Anhydroxylitol

Humectant

Xylitol

Humectant

Saccharide Isomerate

Humectant

Lupinus Albus Seed Extract

Skin Conditioning

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Lactobacillus/Dipteryx Odorata Seed Ferment Filtrate

Skin Conditioning

Sodium PCA

Humectant
0 / 0

Carthamus Tinctorius Seed Oil

Masking
0-2 / 0 Oil IconNot safe for Fungal Acne Icon

Spilanthes Acmella Flower/Leaf/Stem Extract

Antimicrobial

Astragalus Membranaceus Root Extract

Emollient

Sodium Lactate

Buffering

Vegetable Oil

Skin Conditioning
Oil IconNot safe for Fungal Acne Icon

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Aspartic Acid

Masking

Glycine

Buffering
Helps hydrate Dry Skin Icon

Alanine

Masking

Serine

Masking

Valine

Masking

Proline

Skin Conditioning

Threonine

Isoleucine

Skin Conditioning

Histidine

Humectant

Phenylalanine

Masking

Saccharomyces/Zinc Ferment

Skin Conditioning

Saccharomyces/Copper Ferment

Skin Conditioning

Saccharomyces/Magnesium Ferment

Saccharomyces/Iron Ferment

Skin Conditioning

Saccharomyces/Silicon Ferment

Skin Conditioning

Dipalmitoyl Hydroxyproline

Skin Conditioning
Not safe for Fungal Acne Icon

Polyglyceryl-3 Beeswax

Emulsifying
Not safe for Fungal Acne Icon

Asiaticoside

Antioxidant
Antioxidant IconGood for Scar Healing Icon

Madecassic Acid

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Asiatic Acid

Skin Conditioning

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Ubiquinone

Antioxidant
Antioxidant IconHelps with Anti-Aging IconGood for Dark Spots Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Acacia Senegal Gum

Masking

Xanthan Gum

Emulsifying

Boswellia Carterii Gum

Perfuming
Fragrance Icon

Sodium Phytate

Benzyl Alcohol

Perfuming
Alcohol IconFragrance IconPreservative IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Salicylic Acid

Masking
BHA IconPreservative IconGood for Oily Skin IconGood for Minimizing Pores IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Sorbic Acid

Preservative
Preservative Icon

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Sodium Citrate

Buffering
Up The Anti

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning

Butyrospermum Parkii Butter is a plant lipid from the fruit of the Shea Tree. It is an effective skin hydrator and emollient.

Emollients help soothe and soften your skin. It does this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.

Shea butter is rich in antioxidants. Antioxidants help fight free-radicals, or molecules that may harm the body. It is also full of fatty acids including stearic acid and linoleic acid. These acids help replenish the skin and keep skin moisturized.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

Shea butter may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Learn more about Butyrospermum Parkii Butter
Emollient, Skin Conditioning

This oil comes from the seeds of the desert shrub called Jojoba. It is more commonly known as jojoba oil, a non-comedogenic oil.

Jojoba oil does not contain fragrance and has many fatty-acids, making it a great soothing ingredient.

It also contains Vitamin E, a great moisturizing ingredient. Vitamin E is also an antioxidant and protects your skin against oxidative damage.

This ingredient humectant properties, meaning it helps draw moisture from the air. This helps keep your skin hydrated.

While jojoba has antibacterial properties, it is only able to kill some strains of bacteria.

Studies also show it helps in wound healing. In fact, Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.

Fun fact: Jojoba oil similar to natural human skin sebum, so it has a great effect on dry skin. It is also promising with helping to regulate sebum production.

Due to its fatty acid content, Jojoba oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Learn more about Simmondsia Chinensis Seed Oil
Antimicrobial, Antioxidant, Astringent

Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.

This ingredient has many skin benefits:

This ingredient contains polyphenols, a strong antioxidant. Antioxidants help fight off molecules that damage skin cells.

On top of that, the antioxidants in green tea neutralize free-radicals from the sun. This gives the skin some extra UV protection, but should not replace sunscreen.

Many components of tea have anti-inflammatory properties.

Polyphenols and L-theanine help soothe the skin and reduce irritation. The caffeine in Camellia Sinensis Leaf Extract helps calm inflamed blood vessels.

Other compounds found in tea include: Vitamin Bs, linoleic acid, magnesium, calcium, iron, and zinc.

Research has shown both drinking Camellia Sinensis Leaf Tea and applying it to the skin can help boost skin elasticity and hydration. Studies also show using tea extract may reduce sebum, or oil, production.

Learn more about Camellia Sinensis Leaf Extract
Emollient, Masking, Skin Conditioning

Helianthus Annuus Seed Oil is the oil derived from the seeds of a Sunflower. Sunflower seed oil is non-fragrant. It is an emollient, meaning it helps to soften the skin.

Sunflower seed oil contains many fatty acids. The fatty acids found in sunflower seeds include (from highest amount to least): linoleic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, and linolenic acid.

These fatty acids help the skin create ceramides. Ceramides play a role in repairing the skin barrier.

Helianthus Annuus Seed Oil helps moisturize the skin. This in turn helps the skin look more rejuvenated and smoother.

Sunflowers are rich in vitamin E.

Historians believe Indigenous cultures of North America domesticated sunflowers before corn. Thus they relied on sunflower oil for a variety of uses. One such use is moisturizing skin and hair.

Sunflower seed oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Learn more about Helianthus Annuus Seed Oil
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Skin Conditioning

Sodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.

The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.

This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.

Learn more about Sodium PCA
Masking, Skin Conditioning

Carthamus tinctorius seed oil comes from safflower, one of humanity's oldest crops.

Safflower seed oil contains a high percentage of linoleic acid and oleic acid. It also contains Vitamin E. These three components are effective moisturizers.

Vitamin E helps nourish your skin's lipid barrier. It is also a potent antioxidant. Antioxidants help fight free-radical molecules, or unstable molecules that may damage your skin cells.

Due to its high fatty acid content, this ingredient may not be malassezia folliculitis safe.

Thoughout history, safflower has been used for dying fabrics and in food as a saffron substitute.

Learn more about Carthamus Tinctorius Seed Oil
Masking, Skin Conditioning

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.

Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.

Learn more about Arginine
Masking, Skin Conditioning

Aspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.

Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.

Buffering, Skin Conditioning

This ingredient is an amino acid that helps build proteins and moisturizes skin. It is already present in our skin as our bodies produce them naturally.

Glycine already plays a role in helping keep our skin moisturized as amino acids transport moisture throughout our skin.

As collagen is made up of glycine and other amino acids, it is believed glycine may help our skin produce more collagen.

Learn more about Glycine
Masking, Skin Conditioning

Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.

Masking, Skin Conditioning

Serine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.

Amino-acids help give keep our skin hydrated. They play an important role in the skin barrier, which keeps the skin plump and firm.

Serine is a non-essential amino acid, meaning we don't need to obtain it from eating foods.

Learn more about Serine
Masking, Skin Conditioning

Valine is an essential amino acid. It is used by our bodies for tissue repair and muscle growth.

An essential amino acid is one in which our bodies cannot naturally produce so we must get them through diet. Foods such as eggs, dairy, red meat, and fish contain valine.

This ingredient can either be derived from an animal product or be synthetically created.

Learn more about Valine
Skin Conditioning

Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.

Our skin uses proline as one of the building blocks for producing collagen.

In medicine, proline is used as an osmoprotectant. This means it helps prevent oxidative degradation in other drugs.

Our bodies are able to produce proline naturally, but certain conditions may inhibit this production. In that case, proline can be obtained from eating egg whites, soy protein, dairy products, asparagus, mushrooms, and seaweed.

Learn more about Proline

Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.

Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.

Skin Conditioning

Isoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.

Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.

Humectant, Skin Conditioning

Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.

Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.

One study found histidine and carnosine to be a dynamic duo for your skin:

Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.

Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.

Learn more about Histidine
Masking, Skin Conditioning

Phenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.

This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.

Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.

Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.

Learn more about Phenylalanine
Humectant, Moisturising, Skin Conditioning

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

This ingredient helps hydrate, soothe, and protect the skin.

What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.

Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.

Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.

Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.

One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.

The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.

These are some other common types of Hyaluronic Acid:

Learn more about Hyaluronic Acid
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

When to use

2 Routines
50% use in am
50% use in pm
100% use every day
11 Routines
18% use in am
82% use in pm
82% use every day

Reviews

Here's what our community thinks

Maya Chia The Advance Response Complex 64 ingredients

The Advance Response Complex hasn't been rated yet.
Rate it now

Eight Saints Up The Anti 43 ingredients

2.0 /5
from 1 rating
Absorbs Well (1) Broke Me Out (1) Great Value (1)
jess2386's avatar

jess2386

4 months ago
Review

It’s not fungal acne safe. I’ve been using this for 2 years now and it feels amazing but I think I’ll have to retire this because it just makes my skin dull, my nose red, and flares fungal acne. If you’re reading this and you know of an fa safe heavy-ish night cream that have similar ingredients, good for sensitive skin without actives, please leave a comment. I’m on a mission. Also if you aren’t Show more

#great value
#hydrating
#broke me out
#heavy