Esmi Skin Minerals Encapsulated Retinol 0.75% Level 3
Cosmedix Define Age-Defying Treatment
Versus

Esmi Skin Minerals Encapsulated Retinol 0.75% Level 3 Versus Cosmedix Define Age-Defying Treatment

Serum
Facial Treatment
Australian Brand Australia
American Brand United States

Updated on March 22, 2025

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 0 ingredients in common

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any parabens, silicones or sulfates

What's Inside

They both contain oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

New Comparison

Ingredient Info

Click any item below to learn more and see relevant ingredients

Esmi Skin Minerals Encapsulated Retinol 0.75% Level 3 23 ingredients

Cosmedix Define Age-Defying Treatment 49 ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Esmi Skin Minerals Encapsulated Retinol 0.75% Level 3 23 ingredients

Cosmedix Define Age-Defying Treatment 49 ingredients

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Encapsulated Retinol 0.75% Level 3

Water

Skin Conditioning

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Isododecane

Emollient

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Polysorbate 80

Emulsifying
0 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Polyglyceryl-6 Behenate

Emulsion Stabilising
Not safe for Fungal Acne Icon

Polyglyceryl-6 Stearate

Emollient
Not safe for Fungal Acne Icon

Daucus Carota Sativa Seed Oil

Emollient
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Phenoxyethanol

Preservative
Preservative Icon

Caprylyl Glycol

Emollient

Sodium Polyacryloyldimethyl Taurate

Emulsion Stabilising

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconGood for Scar Healing IconNot safe for Fungal Acne Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Disodium EDTA

Inulin Lauryl Carbamate

Emulsion Stabilising

Solanum Lycopersicum Fruit Extract

Antioxidant
Antioxidant Icon

Behentrimonium Chloride

Preservative
Preservative Icon

Sucrose Laurate

Emollient
Not safe for Fungal Acne Icon

Water, Caprylic/Capric Triglyceride, Isododecane, Butylene Glycol, Glycerin, Squalane, Polysorbate 80, Polyglyceryl-6 Behenate, Polyglyceryl-6 Stearate, Daucus Carota Sativa Seed Oil, Glyceryl Stearate, Retinol, Polysorbate 20, Phenoxyethanol, Caprylyl Glycol, Sodium Polyacryloyldimethyl Taurate, Simmondsia Chinensis Seed Oil, Allantoin, Disodium EDTA, Inulin Lauryl Carbamate, Solanum Lycopersicum Fruit Extract, Behentrimonium Chloride, Sucrose Laurate

Define Age-Defying Treatment

Water

Skin Conditioning

Polysorbate 60

Emulsifying
Not safe for Fungal Acne Icon

Lactic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Isopropyl Myristate

Emollient
3-5 / 3 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Hamamelis Virginiana Water

Astringent
Can worsen Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Stearic Acid

Cleansing
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Hydroxide

Buffering

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

Tartaric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Retinyl Acetate

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Albumen

Skin Conditioning

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Benzyl Alcohol

Perfuming
Alcohol IconFragrance IconPreservative IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Malic Acid

Buffering
AHA IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Olea Europaea Fruit Oil

Masking
0-2 / 0 Fragrance IconOil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Pichia/Resveratrol Ferment Extract

Skin Conditioning

Resveratrol Dimethyl Ether

Antioxidant
Antioxidant Icon

Galactoarabinan

Proline

Skin Conditioning

Retinyl Palmitate

Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Citrus Grandis Peel Oil

Masking
Fragrance IconOil Icon

Cananga Odorata Flower Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen IconMay worsen Eczema Icon

Bisabolol

Masking
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Aloe Barbadensis Leaf Juice Powder

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Daucus Carota Sativa Root Extract

Skin Conditioning
Helps reduce irritation Icon

Prunus Amygdalus Dulcis Oil

Skin Conditioning
3 / 0 Oil IconHelps hydrate Dry Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Chamomilla Recutita Flower Extract

Masking
Helps reduce Skin Redness IconHelps reduce irritation Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Althaea Officinalis Root Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Potassium Sorbate

Preservative
Preservative Icon

Limonene

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Sodium Gluconate

Skin Conditioning

BHA

Antioxidant
Antioxidant Icon

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

Caprylhydroxamic Acid

Alcohol Denat.

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

BHT

Antioxidant
Antioxidant Icon

Xanthan Gum

Emulsifying

Phenoxyethanol

Preservative
Preservative Icon

Water, Polysorbate 60, Lactic Acid, Isopropyl Myristate, Glyceryl Stearate, Hamamelis Virginiana Water, Stearic Acid, Cetearyl Alcohol, Glycerin, Sodium Hydroxide, Leuconostoc/Radish Root Ferment Filtrate, Tartaric Acid, Retinyl Acetate, Albumen, Cetyl Alcohol, Benzyl Alcohol, Malic Acid, Olea Europaea Fruit Oil, Retinol, Pichia/Resveratrol Ferment Extract, Resveratrol Dimethyl Ether, Galactoarabinan, Proline, Retinyl Palmitate, Citrus Grandis Peel Oil, Cananga Odorata Flower Oil, Bisabolol, Tocopheryl Acetate, Aloe Barbadensis Leaf Juice Powder, Allantoin, Daucus Carota Sativa Root Extract, Prunus Amygdalus Dulcis Oil, Helianthus Annuus Seed Oil, Chamomilla Recutita Flower Extract, Tocopherol, Althaea Officinalis Root Extract, Alcohol, Citric Acid, Polysorbate 20, Potassium Sorbate, Limonene, Sodium Gluconate, BHA, Behenyl Alcohol, Caprylhydroxamic Acid, Alcohol Denat., BHT, Xanthan Gum, Phenoxyethanol

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Encapsulated Retinol 0.75% Level 3
10
10
10
liked
mixed
disliked
Unlock with Premium
Define Age-Defying Treatment
10
10
10
liked
mixed
disliked
not rated
Unlock with Premium

When to use

Esmi Skin Minerals Encapsulated Retinol 0.75% Level 3 23 ingredients

Cosmedix Define Age-Defying Treatment 49 ingredients

1 Routine
0% use in am
100% use in pm
100% use every other_day
3 Routines
0% use in am
100% use in pm
100% use every day
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