Versus

Anua PDRN Hyaluronic Acid 100 Moisturizing Cream Versus Centellian24 The Madeca Cream

General Moisturizer
General Moisturizer
Korean Brand
Korean Brand

Updated on April 16, 2025

Overview

What they are

These products are both cruelty-free and reef safe general moisturizers. They have a total of 11 ingredients in common

Cool Features

They both contain hyaluronic acid and niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain fragrances and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
PDRN Hyaluronic Acid 100 Moisturizing Cream

Water

Skin Conditioning

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Pentylene Glycol

Skin Conditioning

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Sodium Dna

Skin Conditioning
Helps with Anti-Aging IconGood for Dark Spots Icon

Hydrolyzed Collagen

Emollient
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Melia Azadirachta Leaf Extract

Skin Conditioning

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Melia Azadirachta Flower Extract

Skin Conditioning

Coccinia Indica Fruit Extract

Skin Conditioning

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Aloe Barbadensis Flower Extract

Emollient

Solanum Melongena Fruit Extract

Skin Conditioning

Ocimum Sanctum Leaf Extract

Skin Conditioning
Good for Dark Spots Icon

Corallina Officinalis Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Curcuma Longa Root Extract

Masking
Fragrance Icon

Centella Asiatica Leaf Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Diphenylsiloxy Phenyl Trimethicone

Skin Conditioning
Silicon Icon

PCA Dimethicone

Skin Conditioning
Silicon Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Diglycerin

Humectant
Helps hydrate Dry Skin Icon

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

C12-20 Alkyl Glucoside

Emulsifying

Methylpropanediol

Solvent

Ethylhexylglycerin

Skin Conditioning

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Sodium Phytate

Aminomethyl Propanediol

Buffering

Pvm/Ma Copolymer

Emulsion Stabilising

Madecassoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

C12-13 Alketh-9

Emulsifying

Dimethylsilanol Hyaluronate

Humectant

Hydrolyzed Sodium Hyaluronate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Scar Healing Icon

Asiaticoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Potassium Hyaluronate

Skin Conditioning

Hydroxypropyltrimonium Hyaluronate

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Sodium Hyaluronate Dimethylsilanol

Humectant

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

C14-22 Alcohols

Emulsion Stabilising

Carbomer

Emulsion Stabilising
1 / 0
The Madeca Cream

Lactobacillus/Centella Asiatica Extract Ferment Filtrate

Skin Conditioning

Dipropylene Glycol

Masking

Hydrogenated Polydecene

Emollient

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Cyclohexasiloxane

Emollient
Silicon Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Pentaerythrityl Tetraethylhexanoate

Emollient
Helps hydrate Dry Skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Polyglyceryl-6 Distearate

Emulsifying
Not safe for Fungal Acne Icon

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Dicaprylyl Ether

Emollient
Helps hydrate Dry Skin Icon

Centella Asiatica Leaf Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Olea Europaea Fruit Oil

Masking
0-2 / 0 Fragrance IconOil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Centella Asiatica Oil

Antimicrobial
Antioxidant IconOil Icon

Hydrolyzed Centella Asiatica Protein

Humectant

Ascorbyl Palmitate

Antioxidant
2 / 0 Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconNot safe for Fungal Acne Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Centella Asiatica Callus Culture

Antioxidant
Antioxidant Icon

Collagen Amino Acids

Moisturising
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Sodium Starch Octenylsuccinate

Absorbent

Macadamia Ternifolia Seed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Beeswax

Emulsion Stabilising
0-2 / 0 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Sodium Stearoyl Glutamate

Cleansing

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Madecassic Acid

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Asiaticoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Jojoba Esters

Emollient
Not safe for Fungal Acne Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Dimethicone/Vinyl Dimethicone Crosspolymer

Skin Conditioning
Silicon Icon

Asiatic Acid

Skin Conditioning

Polyglyceryl-3 Beeswax

Emulsifying
Not safe for Fungal Acne Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Candida/Garcinia Cambogia Ferment

Xanthan Gum

Emulsifying

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Sorbitan Isostearate

Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon

Sodium Laurate

Cleansing

Lauric Acid

Cleansing
4 / 1 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Tromethamine

Buffering

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Glycine

Buffering
Helps hydrate Dry Skin Icon

Glutamic Acid

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Phytosphingosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Ethylhexylglycerin

Skin Conditioning

Water

Skin Conditioning

Stearyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Disodium EDTA

Pelargonium Graveolens Flower Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Citrus Aurantium Dulcis Peel Oil

Masking
Oil Icon

Eucalyptus Globulus Leaf Oil

Perfuming
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Lavandula Angustifolia Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Limonene

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Citronellol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Geraniol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Antioxidant, Skin Conditioning

Asiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.

Asiaticoside is an antioxidant and helps with wound healing. It has been shown to increase antioxidant activity during the wound healing process.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Skin Conditioning

Centella Asiatica Leaf Extract comes from the leaves of an herb plant native to Southeast Asia. Centella Asiatica is rich in antioxidants and amino acids. It can help reduce irritation and soothe the skin.

Many active components found in centella asiatica, such as Madecassic Acid and Asiaticoside, encourage the skin to naturally produce hyaluronic acid. This helps keep our skin hydrated. Many of these components also show antioxidant activity and may help reduce the signs of aging.

Research shows centella asiatica can help increase Type I collagen production by increasing fibroblast production. Fibroblast helps form connective tissue.

The combination of all these properties makes centella asiatica leaf extract effective at soothing the skin.

Other components of centella asiatica leaf extract include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Recent studies found madecassoside may help prevent damage from UV rays by preventing UV-induced inflammation. Further research is needed.

This plant has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Leaf Extract
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.

Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

64 Routines
42% use in am
58% use in pm
98% use every day
When to use See routines that use it ->
21 Routines
48% use in am
52% use in pm
71% use every day

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Works Well 100% Absorbs Well 67% Hydrating 67%
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