The Saem Cleome Refining Dual Mask Wash Off
A face cleanser with 50 ingredients, including BHA and exfoliants.
This salicylic acid clay cleanser is formulated around Salicylic Acid to clear breakouts and unclog pores.
Worth noting
Contains Salicylic Acid, an exfoliating acid best introduced gradually.
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
Water
Skin ConditioningBentonite
AbsorbentKaolin
AbrasiveCI 77891
Cosmetic ColorantCetearyl Alcohol
EmollientChondrus Crispus Extract
Skin ConditioningSaccharum Officinarum Extract
Moisturising1,2-Hexanediol
Skin ConditioningPalmitic Acid
EmollientStearic Acid
CleansingTriethanolamine
BufferingGlyceryl Stearate Se
EmulsifyingCetyl Ethylhexanoate
EmollientMoroccan Lava Clay
AbrasivePanthenol
Skin ConditioningMagnesium Aluminum Silicate
AbsorbentMontmorillonite
AbsorbentPhenoxyethanol
PreservativeIllite
AbrasiveXanthan Gum
EmulsifyingQuartz
AbrasiveCaprylyl Glycol
EmollientCI 77288
Cosmetic ColorantEthylhexylglycerin
Skin ConditioningCI 77007
Cosmetic ColorantButylene Glycol
HumectantParfum
MaskingDisodium EDTA
Oenothera Biennis Flower Extract
AstringentPropanediol
SolventMyristic Acid
CleansingRhus Semialata Gall Extract
Skin ConditioningSalicylic Acid
MaskingArachidic Acid
CleansingFomes Officinalis Extract
Skin ProtectingLauric Acid
CleansingOleic Acid
EmollientGlycerin
HumectantCamellia Japonica Flower Extract
EmollientEnantia Chlorantha Bark Extract
Skin ConditioningCleome Gynandra Leaf Extract
AntiseborrhoeicRosa Multiflora Fruit Extract
MaskingChamaecyparis Obtusa Leaf Extract
Skin ConditioningOriganum Vulgare Leaf Extract
Skin ConditioningSalix Alba Bark Extract
AstringentCinnamomum Cassia Bark Extract
MaskingLactobacillus/Soybean Ferment Extract
Skin ConditioningPortulaca Oleracea Extract
Skin ConditioningScutellaria Baicalensis Root Extract
AstringentOleanolic Acid
Skin ConditioningWater, Bentonite, Kaolin, CI 77891, Cetearyl Alcohol, Chondrus Crispus Extract, Saccharum Officinarum Extract, 1,2-Hexanediol, Palmitic Acid, Stearic Acid, Triethanolamine, Glyceryl Stearate Se, Cetyl Ethylhexanoate, Moroccan Lava Clay, Panthenol, Magnesium Aluminum Silicate, Montmorillonite, Phenoxyethanol, Illite, Xanthan Gum, Quartz, Caprylyl Glycol, CI 77288, Ethylhexylglycerin, CI 77007, Butylene Glycol, Parfum, Disodium EDTA, Oenothera Biennis Flower Extract, Propanediol, Myristic Acid, Rhus Semialata Gall Extract, Salicylic Acid, Arachidic Acid, Fomes Officinalis Extract, Lauric Acid, Oleic Acid, Glycerin, Camellia Japonica Flower Extract, Enantia Chlorantha Bark Extract, Cleome Gynandra Leaf Extract, Rosa Multiflora Fruit Extract, Chamaecyparis Obtusa Leaf Extract, Origanum Vulgare Leaf Extract, Salix Alba Bark Extract, Cinnamomum Cassia Bark Extract, Lactobacillus/Soybean Ferment Extract, Portulaca Oleracea Extract, Scutellaria Baicalensis Root Extract, Oleanolic Acid
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterBentonite is an aluminium phyllosilicate clay with great absorbent properties. The name 'bentonite' comes from the area where the largest source is found: Fort Benton, Wyoming.
As a clay, bentonite is often used to absorb excess oil and provide exfoliation. It has also been shown to have some antibacterial and anti-inflammatory properties. Studies show bentonite was effective at calming dermatitis from poison ivy and in diaper dermatitis of infants. Bentonite has also been shown to act as a barrier against toxic compounds on your skin.
Sunscreens containing bentonite display higher water resistance and stay on the skin for much longer. The sunscreens containing bentonite also show higher potency and UV light absorbtion.
Bentonite is naturally created from volcanic ash and several natural weathering/hydrothermal processes.
A common usage of bentonite is removing excess protein from white wines. Bentonite contains a property of being able to absorb large amounts of protein from aqueous solutions.
Phyllosilicate clay has a structure formed by sheets.
Learn more about BentoniteKaolin is a clay. It is used for oil control and to help minimize pores. Like other clays, kaolin has the ability to absorb excess sebum or oil. This can help clean out pores and mattify the skin.
Some types of kaolin may have exfoliating properties. When water is added to kaolin, it becomes a paste with small abrasive particles.
Most kaolin is a white color, but may be pink/orange/red depending on where it comes from.
The name 'kaolin' comes from a Chinese village named 'Gaoling'. Kaolin clay comes from rocks rich in kaolinite. Kaolinite, the mineral, has a silicate layered structure. Kaolinite is formed from chemical weathering of aluminum siilicate minerals.
Besides skincare, kaolin is commonly used to make glossy paper, in ceramics, toothpaste, and as medicine to soothe stomach issues.
Learn more about KaolinCi 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.
It's main function is to add a white color to cosmetics. It can also be mixed with other colors to create different shades.
Ci 77891 is commonly found in sunscreens due to its ability to block UV rays.
Learn more about CI 77891Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Learn more about Cetearyl AlcoholChondrus Crispus Extract comes from a red algae native to the northern Atlantic coasts of Europe and North America. It helps hydrate the skin and is rich in antioxidants.
The antioxidants in chondrus crispus include lutein and zeaxanthin. Lutein has the ability to filter blue light from screens.
Other contents of chondrus crispus include polysaccharides, peptides, and amino acids. These help hydrate the skin.
What's the difference between algae and seaweed?
Algae is a broad term that includes seaweed. Not all algae is seaweed.
This ingredient is also called sugarcane extract. It is a moisturizing humectant and has skin soothing properties.
Similar to hyaluronic acid, sugarcane can attract moisture to your skin.
Glycolic acid is a derivative of sugarcane. While glycolic acid is an AHA with exfoliating properties, sugarcane is not an AHA.
A study from 2021 found the compounds in sugarcane extract to have antioxidant, antimicrobial, and anti-inflammatory activity. The study also suggests these compounds can inhibit skin ageing enzymes and promote collagen synthesis.
Learn more about Saccharum Officinarum Extract1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Palmitic Acid is a fatty acid naturally found in our skin and in many plant and animal sources.
In cosmetics, it is usually derived from palm oil. It serves many purposes in skincare, acting as a cleanser, emollient, and emulsifier.
Interestingly, topically applied Palmitic Acid can be elongated into longer chain fatty acids and ceramides. A 2019 study found low levels of Palmitic Acid lead to slower development of cells, suggesting it plays a role in keeping your skin's renewal process on track.
The CIR (Cosmetic Ingredient Review) panel determined it safe as used in cosmetics at concentrations up to 13%. It is non-irritating and non-sensitizing in clinical studies.
The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Palmitic Acid, at C16, falls right into that sweet spot.
In vitro studies have shown that Palmitic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.
It's worth noting that what feeds yeast in a lab doesn't necessarily feed it on your face since formulation and your skin's chemistry play a bigger role.
Learn more about Palmitic AcidStearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Learn more about Stearic AcidTriethanolamine (TEA) is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.
As an emulsifier, it prevents ingredients from separating and enhances texture by adding volume to a product.
PH adjusters are common in cosmetic products. The pH of a product can affect the effectiveness of other ingredients. A product with a high pH may also irritate the skin.
If you are looking for the tea leaf ingredient, click here.
Learn more about TriethanolamineGlyceryl Stearate Se is a self-emulsifying (SE) form of glyceryl stearate. Self-emusifying means this ingredient automatically blends with water. It is an emulsifier, emollient, and cleansing agent.
As an emulsifier, Glyceryl Stearate Se prevents ingredients such as oil and water from separating. It is also a surfactant, meaning it helps cleanse the skin. Surfactants help gather oil, dirt, and other pollutants so they may be rinsed away easily.
Emollients help your skin stay smooth and soft. It does so by creating a film on top of the skin that helps trap moisture in.
Learn more about Glyceryl Stearate SeCetyl Ethylhexanoate is an emollient ester. It comes from cetearyl alcohol and 2-ethylhexanoic acid.
Cetyl Ethylhexanoate is an emollient that adds a velvety feel to skin without being greasy or oily. Emollients help trap moisture into your skin, keeping your skin soft and hydrated.
This ingredient is also known as rhassoul clay.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolMagnesium Aluminum Silicate is a type of silica. It comes from naturally occuring minerals such as silicate ores and clay.
Magnesium aluminum silicate is used for enhancing texture and as an absorbent. Due to its large molecular size, it is unable to be absorbed into the skin.
Like other types of silica, this ingredient can be used to thicken a product. As an absorbent, it may be used to absorb extra water or help prevent clumping.
Although “aluminum” in an ingredient name can raise red flags for some consumers, the form and usage context matter significantly. For typical topical applications, there is no substantial evidence of health risks - such as cancer, neurotoxicity, or systemic “aluminum overload.”
Learn more about Magnesium Aluminum SilicateMontmorillonite is a clay (aluminomagnesium silicate) with strong absorption properties. It has a similar pH to skin.
This clay is named after Montmorillon in France.
Learn about other types of clay, such as Kaolin, Bentonite, or Fuller's Earth.
Learn more about MontmorillonitePhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolIllite is an exfoliant.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolCi 77288 is used to add green pigment to products.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinThis pigment is called Ultramarine blue lazurite. It gives a saturated blue color, but can be used to create other colors as well.
According to the manufacturer, it is usually made from kaolin, sodium sulfate, sodium carbonate, sulfur, and charcoal.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAWe don't have a description for Oenothera Biennis Flower Extract yet.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolMyristic Acid, aka tetradecanoic acid, is a naturally occurring fatty acid found in coconut oil and palm oil.
In skincare, it is an:
Research indicates that this ingredient posts a low risk of irritation and sensitization.
Since myristic acid is a C14 fatty acid, it falls within the range that Malassezia can metabolize, and therefore not fungal acne safe.
Learn more about Myristic AcidWe don't have a description for Rhus Semialata Gall Extract yet.
Salicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.
Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.
Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.
Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.
It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.
While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.
If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.
Learn more about Salicylic AcidArachidic Acid (also known as Eicosanoic acid) is a fatty acid naturally found in peanut oil, corn oil, or cocoa butter. In cosmetics, it is an emollient, emulsifier, and cleansing ingredient.
Like other fatty acids, it functions as an emollient that helps hydrate and smooth the skin.
As an emulsifier and cleansing agent, it helps stabilize oil-in-water formulations. This also allows oils and other impurities to be easily rinsed away.
Arachidic acid is a natural component of human sebum and research has found that patients with papulopustular rosacea show reduced levels of these fatty acids compared to healthy control groups.
This ingredient may not be safe for fungal acne because it falls within the carbon chain range that Malassezia can metabolize.
Learn more about Arachidic AcidWe don't have a description for Fomes Officinalis Extract yet.
Lauric Acid is a saturated fatty acid naturally found in coconut oil, palm kernel oil, and even breast milk.
In cosmetics, it is an:
Lab studies have found that lauric acid is surprisingly good at killing acne-causing bacteria. However, these tests were done on bacteria in a petri dish and not on real skin, so we can't say for certain it works the same in a formulation on a real face.
The comedogenic rating of 4 comes from the 1972 rabbit ear model using undiluted ingredients. Comedogenicity is highly individual and one comedogenic ingredient cannot predict how a formula will behave on skin.
This ingredient is not fungal acne safe and research has confirmed Malassezia can use it as a food source. Even though "fungal acne" has the word "acne" in it, they are completely different. Regular acne is driven by a bacteria called Cutibacterium acnes, clogged pores, and excess oil. Fungal acne isn't really acne; it's caused by an overgrowth of a yeast called Malassezia that already lives on everyone's skin. Because one is bacterial and the other is fungal, they respond to different ingredients.
Learn more about Lauric AcidOleic Acid is an Omega-9 fatty acid that can be found naturally in your skin's sebum and in many plant oils such as avocado and olive oil.
It is an emollient that helps soften skin and prevent moisture loss.
Research shows:
A 1998 study did find that applying oleic acid at higher concentrations may cause irritation and disrupt the skin barrier. Modern formulations typically use low levels that is well-tolerated.
The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Oleic Acid, at C18, falls right into that sweet spot.
In vitro studies have shown that Oleic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.
Learn more about Oleic AcidGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCamellia Japonica Flower Extract comes from the Japanese Camellia plant (a cousin of the green tea plant). This plant is native to East Asia and known as "Tsubaki" in Japanese.
It's a flower extract packed with flavonoids and phenolic acids that give it most of its skincare value. In lab tests on human skin cells, the ethanol extract of the flower mopped up free radicals and boosted the skin's own antioxidant enzymes.
A separate study found the flower extract had solid antioxidant activity and reduced the reactive oxygen species that urban air pollution triggers in skin cells.
Newer work also points at anti-aging and calming effects:
One 2025 paper tied the extract and its component hyperoside to collagen III and elastin production plus better skin-barrier protein expression. A mouse study on eczema-like skin found four weeks of topical camellia extract reduced inflammation and itch-related markers.
Just know that most of these studies are cell-culture and animal work and not human trials. For now, it's best to treat it as a nice supporting antioxidant rather than a headline active.
At this time, there's no published regulatory use-level for this specific ingredient; suppliers usually sell it as a water/glycerin-based extract used in the low single-digit percent range.
There's no published contact-allergy case reports for this ingredient but as with any botanical, a patch test is sensible if you react to plant extracts generally.
Learn more about Camellia Japonica Flower ExtractWe don't have a description for Enantia Chlorantha Bark Extract yet.
We don't have a description for Cleome Gynandra Leaf Extract yet.
We don't have a description for Rosa Multiflora Fruit Extract yet.
This ingredient comes from the leaves of the Japanese cypress tree that is also called Hinoki. The leaves are rich in flavonoids with quercitrin being one of its key actives.
A 2023 study tested a 70% ethanol extract on UVA-stressed, collagen-producing skin cells. Across multiple antioxidant tests, this extract protected skin from free radicals at meaningful rates.
And the coolest part? At 1000 µg/mL, it blocked two enzymes (collagenase and elastase) almost as well as vitamin C did at the same dose. Collagenase and elastase are the enzymes that break down your skin's collagen and elastin over time.
The same study found this ingredient lowered skin-breakdown enzymes and inflammation signals while bumping up collagen production in UV-stressed cells.
A 2024 follow-up tested a fermented version (fermented with mushroom) and it calmed down several key inflammation markers in irritated immune cells. So besides anti-aging, this ingredient can also help soothe skin.
Most of the data right now is still at the cell-culture stage rather than from human clinical trials. However, there's no harm in adding this ingredient to your routine.
Just be sure to patch test if you have a history of sensitivity toward botanical extracts.
Learn more about Chamaecyparis Obtusa Leaf ExtractOregano leaf is a culinary and medicinal herb with skin conditioning properties.
Salix Alba Bark Extract comes from the bark of the white willow tree. The official CosIng listing states this ingredient to have astringent, skin conditioning, soothing, and tonic properties.
Its star compound is salicin, a natural glucoside that is chemically related to salicylic acid. That's why you'll often see it marketed as a "natural BHA alternative" but that's a bit of a stretch.
Your skin can't convert salicin to salicylic acid because it needs specific enzymes that aren't present on the skin's surface. It won't behave like true salicylic acid, especially at the concentrations used in cosmetics.
However, this ingredient has its own perks. It contains flavonoids, polyphenols, and tannins that give it proven antioxidant and soothing properties.
An 8-week clinical study found a cream with 2% of this extract improved skin microcirculation, elasticity, and dark circles. This is most likely due to its role in increasing hyaluronic acid synthesis in fibroblasts and improved vascular integrity.
Another study found a topical serum with 0.5% salicin showed improvements in visible signs of aging, hyperpigmentation, and texture.
Just be careful if you have a known aspirin/salicylate allergy and be sure to consult with a medical professional about using this ingredient if you do.
Fun fact: Willow Bark extract has been used for thousands of years and ancient civilizations used white willow to help treat pain and fevers.
Learn more about Salix Alba Bark ExtractThis ingredient comes from the cinnamon tree native to southern China.
Though cinnamon has a wonderful taste, it can cause skin irritation due to its rich coumarins, cinnamaldehyde, and styrene content.
Lactobacillus/Soybean Ferment Extract is the result of fermenting soybeans with the Lactobacillus bacteria. It mainly acts as a skin conditioning agent in a formula, and the interesting part is what fermentation does to the soy.
Fermenting soy:
The isoflavones are the workhorses behind the common claims; lab and animal studies show they mop up free radicals, help protect skin cells from UVB damage, and nudge fibroblasts to make more collagen while slowing the enzymes that break collagen down.
One controlled clinical study using an isoflavone cream reported softer wrinkles and better skin texture over time. A topical fermented soy extract also improved hydration and elasticity in an animal aging model.
The big caveat is that most of this evidence comes from soy isoflavones and related fermented soy extracts rather than this exact INCI. Some of the strongest data also comes from oral studies.
So it's best to think of this ingredient as a gentle, antioxidant-leaning conditioning agent rather than a proven wrinkle eraser.
At this time, there's no published concentration levels for this specific ferment but it usually shows up at modest levels in real products (~1% or less).
One last thing for people with soy allergies: it's always worth patch testing this ingredient despite the lowered allergy risk.
Learn more about Lactobacillus/Soybean Ferment ExtractThis extract comes from Purslane, a succulent. It has anti-inflammatory, antioxidant, and hydrating properties.
Purslane is very nutritious. It contains omega-3 fatty acids, NMFs, many vitamins, minerals, and antioxidants. The vitamins found in purslane include: Vitamin C, Vitamin A, and Vitamin E.
Fun fact: Purslane is a succulent with an extensive habitat. It is used in traditional Korean medicine to treat irritated skin.
Nowadays, purslane is becoming a superfood due to its highly nutritious content.
Learn more about Portulaca Oleracea ExtractScutellaria Baicalensis Root Extract comes from the Baikal skullcap or Chinese skullcap plant. This plant is native to Northeast Asia and can be found in China, Mongolia, Korea, and Siberia.
In cosmetics, Scutellaria Baicalensis Root Extract provides antioxidant and anti-inflammatory benefits. This is due to the flavonoid composition of Scutellaria Baicalensis Root Extract.
In Chinese traditional folk medicine, Scutellaria Baicalensis Root Extract is used to help treat lung issues and hypertension.
Learn more about Scutellaria Baicalensis Root ExtractOleanolic acid is a type of triterpene.
Triterpenes are chemical compounds found in various plants such as pomegranates, apples, basil, and rosemary. They have been shown to have anti-inflammatory and antioxidant properties.
Reviews
No written reviews yet. Be the first to review this product.
Recent searches
Search reviews by skin type, ingredient, or keyword.
Where it's from
The Saem is a Korean brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated August 4, 2026 • Added by crysv2797