Panah Labs Brightening Cream SPF 50

Panah Labs Brightening Cream SPF 50

This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.

Worth noting

Contains drying alcohol, which absorbs quickly but can be dehydrating.

We independently verify ingredients, backed by peer-reviewed research. Suggest an update.

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What's inside

Ingredients List

24
26
5

Butyloctyl Salicylate

Skin Conditioning
Non-Reef-Safe Icon

Diethylamino Hydroxybenzoyl Hexyl Benzoate

UV Filter
Chemical UV Filter Icon

Dimethicone

Emollient
1 / 0 Silicon IconGood for Scar Healing Icon

Cyclopentasiloxane

Emollient
Silicon Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconGood for Barrier Repair Icon

Propylene Glycol

Humectant
0 / 0 Helps hydrate Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Ethylhexyl Methoxycinnamate

UV Absorber
0 / 0 UV Protection IconChemical UV Filter IconMay cause irritation IconNon-Reef-Safe Icon

Butyl Methoxydibenzoylmethane

UV Absorber
UV Protection IconChemical UV Filter Icon

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Phenoxyethanol

Preservative
Preservative Icon

Octocrylene

UV Absorber
UV Protection IconChemical UV Filter IconMay worsen Eczema IconMay cause irritation IconNon-Reef-Safe Icon

Niacinamide

Smoothing
Niacinamide IconHelps fight Acne IconHelps with Anti-Aging IconHelps brighten skin IconHelps reduce irritation IconGood for Oily Skin IconGood for Minimizing Pores IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Dark Spots IconGood for Skin Texture IconGood for Barrier Repair Icon

Acrylates Copolymer

Gossypium Herbaceum Callus Culture

Skin Conditioning

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Barrier Repair Icon

PEG-40 Hydrogenated Castor Oil

Emulsifying
Oil IconNot safe for Fungal Acne Icon

Acetyl Glucosamine

Skin Conditioning
Helps with Anti-Aging IconHelps brighten skin IconGood for Dark Spots Icon

Disodium EDTA

Linum Usitatissimum Seed Oil

Perfuming
Oil IconFragrance IconBad for Acne Prone Skin IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Eczema IconMay cause irritation IconMay worsen Rosacea Icon

Titanium Dioxide

Cosmetic Colorant
0 / 0 UV Protection IconMineral UV Filter IconNon-Reef-Safe Icon

Phospholipids

Skin Conditioning
Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Broussonetia Kazinoki Root Extract

Skin Conditioning

Xanthan Gum

Emulsifying

Citrus Aurantifolia Oil

Cleansing
Oil IconEssential Oil IconFragrance Icon

Orange Roughy Oil

Skin Conditioning
Oil Icon

Lecithin

Emollient
Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Pyrus Malus Fruit Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Morus Alba Bark Extract

Skin Conditioning

Camellia Japonica Leaf Extract

Skin Conditioning

Centella Asiatica Extract

Cleansing
Helps with Anti-Aging IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Skin Texture IconGood for Barrier Repair Icon

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps with Anti-Aging IconHelps hydrate Dry Skin IconHelps brighten skin IconHelps reduce irritation IconGood for Oily Skin IconGood for Minimizing Pores IconHelps reduce Skin Redness Icon

Garcinia Mangostana Peel Extract

Skin Conditioning

Citric Acid

Buffering
AHA IconHelps brighten skin IconMay worsen Rosacea Icon

Tricholoma Matsutake Extract

Skin Conditioning

Arbutin

Antioxidant
Arbutin IconAntioxidant IconHelps brighten skin IconGood for Scar Healing IconGood for Dark Spots Icon

Hydrated Silica

Abrasive
Exfoliant Icon

Eucommia Ulmoides Bark Extract

Antioxidant
Antioxidant Icon

Bromelain

Skin Conditioning
Good for Skin Texture Icon

Galactoarabinan

Helps reduce Skin Redness Icon

Glucose

Humectant
Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Aluminum Hydroxide

Emollient

Hydrolyzed Pea Protein

Emollient

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon

Sodium Chloride

Masking

Methicone

Emollient
Silicon Icon

Glutathione

Helps brighten skin IconHelps reduce Skin Redness IconGood for Dark Spots Icon

Gluconolactone

Skin Conditioning
PHA IconHelps fight Acne IconHelps with Anti-Aging IconHelps brighten skin IconGood for Oily Skin IconGood for Minimizing Pores IconGood for Scar Healing IconGood for Skin Texture Icon

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Scar Healing IconGood for Dark Spots IconGood for Barrier Repair IconNot safe for Fungal Acne Icon

Linolenic Acid

Cleansing
Fragrance IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconNot safe for Fungal Acne Icon

Sodium Benzoate

Masking
Preservative Icon

Sodium Succinate

Buffering

Ascorbyl Palmitate

Antioxidant
2 / 0 Vitamin C IconAntioxidant IconHelps brighten skin IconGood for Scar Healing IconNot safe for Fungal Acne Icon

Calcium Gluconate

Humectant

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning, Solvent, UV Filter

Butyloctyl Salicylate is a chemical UV filter structurally similar to octisalate. It is a photostabilizer, SPF booster, emollient and solvent. This ingredient helps evenly spread out ingredients.

According to a manufacturer, it is suitable for pairing with micro Titanium Dioxide, Zinc Oxide, and pigments.

Photostabilizers help stabilize UV-filters and prevents them from degrading quickly.

Learn more about Butyloctyl Salicylate

Diethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB) is a chemical UV-A absorber. It is formulated for high UVA protection (320-400 nm).

DHHB is well-liked for:

DHHB has been approved by the EU, Japan, Taiwan, and South America for use up to 10%. Unfortunately, it has not been approved for use in the US or Canada due to slow regulatory processes.

This ingredient is soluble in oils, fats, and lipids.

Learn more about Diethylamino Hydroxybenzoyl Hexyl Benzoate
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Emollient, Skin Conditioning, Solvent

Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy.

Since D5 is volatile, it does its thing and then evaporates off the skin quickly.

The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics

There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels.

Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5.

The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water.

Learn more about Cyclopentasiloxane
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Humectant, Skin Conditioning, Skin Protecting

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Skin Conditioning, Solvent

Propylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.

As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.

The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.

True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).

It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.

Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.

Learn more about Propylene Glycol
UV Absorber, UV Filter

This ingredient is also known as Octinoxate and is one of the oldest and most widely used chemical UV filters in skincare.

It has a simple job: soap up UVB radiation (290-320 nm), the wavelengths responsible for sunburn and a big chunk of long-term sun damage.

In formulas, it's always paired with a separate UVA filter because octinoxate solely protects skin from UVB.

Because it's an oil-soluble liquid, it's easy to blend into the oil phase of lotions/creams and gives a cosmetically elegant feel.

The one quirk about formulating this ingredient is photostability; the molecule slowly changes shape into a less effective version when sunlight hits it. So the longer you're in the sun, the weaker its protection gets. The drop can be more than 30% in some formulas.

It also doesn't play nice with Avobenzone (the common UVA filter) since avobenzone destabilizes octinoxate and the two degrade each other. But don't worry: brands have solved this issue by adding photostabilizers like Tinosorb S to prevent degradation and keep SPF stable under heavy UV exposure.

The maximum allowed level is 10% in the EU and Australia, 7.5% in the US and Canada, and 20% in Japan.

The Cosmetic Ingredient Review Panel has concluded this ingredient to be safe in cosmetics up to 10%.

One last thing worth knowing for context:

Octinoxate has been the subject of ongoing review in Europe where the Scientific Committee on Consumer Safety's (SCCS) 2025 final opinion is that this ingredient is an endocrine-active substance.

Lab and animal studies suggest it can act a bit like a hormone in the body (mildly mimicking estrogen and slightly blocking male hormones). It's important to know this hasn't really been shown to happen in everyday human use.

This ingredient is also banned in Hawaii over coral reef concerns.

Learn more about Ethylhexyl Methoxycinnamate
UV Absorber, UV Filter

Also known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm).

It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation.

This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent.

Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation.

The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries.

It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity.

Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years.

Learn more about Butyl Methoxydibenzoylmethane

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.

Preservative

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Learn more about Phenoxyethanol
UV Absorber, UV Filter

Octocrylene is an oil-soluble organic UV filter that mainly absorbs UVB and short wave UVA II light.

Its real superpower is teamwork: octocrylene is remarkably photostable and is most famous for stabilizing avobenzone (the workhorse UVA filter).

This ingredient is commonly used to enhance both UVB and UVA protection due to its unique property in stabilizing avobenzone. It also pulls double duty by boosting water resistance and giving formulas a smooth, spreadable feel.

The EU's Scientific Committee on Consumer Safety (SCCS) has deemed octocrylene to be safe as a UV-filter at concentrations up to 10% (capped at 9% in propellant sprays). The US also permits it up to 10%.

Two things worth knowing:

You'll usually see this ingredient used in concentrations between 2-10% (higher amounts when used as a stabilizer for avobenzone).

Learn more about Octocrylene
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide

Acrylates Copolymer is used as a film-forming agent and texture enhancer.

After applied, Acrylates Copolymer forms a thin film cover that helps skin feel more soft. It can help sunscreens become more water-resistant.

It is also used to make a product more thick.

Learn more about Acrylates Copolymer

We don't have a description for Gossypium Herbaceum Callus Culture yet.

Skin Conditioning, Skin Protecting, Soothing

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Learn more about Allantoin
Emulsifying, Surfactant

PEG-40 Hydrogenated Castor Oil is an emulsifier derived from castor oil.

As an emulsifying agent, it helps other ingredients like fragrances and fat-soluble vitamins dissolve cohesively.

Due to its large molecule size, it doesn't penetrate beyond the skin's surface.

This ingredient has a solid regulatory track record; the CIR Expert Panel first concluded it was safe for use in cosmetics at concentrations up to 100% in 1997. A 2012 reassessment reaffirmed that finding. Safety studies have also found no irritation or evidence of toxicity.

A 2019 study did find this ingredient to grow Malassezia, so this ingredient may not be fungal acne safe.

Learn more about PEG-40 Hydrogenated Castor Oil
Skin Conditioning

Acetyl Glucosamine is an antioxidant and humectant. It is an amino acid sugar and is naturally found in our skin.

The cool thing about this ingredient? It helps the skin produce hyaluronic acid and boost hydration. It also has antioxidant benefits to protect skin cells.

When paired with niacinamide, Acetyl Glucosamine has been shown to be effective at reducing discoloration.

Learn more about Acetyl Glucosamine

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Learn more about Disodium EDTA
Perfuming, Skin Conditioning

This ingredient is also known as flaxseed oil or linseed oil. It is created by cold-pressing the seeds of the flax plant and is rich in fatty acids.

This oil is packed with omega-3 (ALA), omega-6, and omega-9 fatty acids that closely mimic the skin's own natural lipid barrier. The high omega-3 content gives it solid anti-inflammatory properties.

Clinical studies have found it can reduce water loss and improve smoothness/hydration, particularly in sensitive skin types. Studies also suggest it helps maintain the lipid layer that is compromised in atopic (eczema-prone) skin.

Wound healing studies showed that low-concentration linseed oil formulations (1-5%) produced significant barrier repair, but it should be noted that high concentrations showed diminishing returns.

Due to the rich fatty acid content, this ingredient may not be fungal acne safe.

Learn more about Linum Usitatissimum Seed Oil
Antimicrobial, Astringent, Masking

This ingredient is also called ethanol or ethyl alcohol. It is denatured, meaning made undrinkable for cosmetic use.

In formulas, it:

Is it bad for your skin?

The answer comes down to concentration. Patch and wash studies have found highly concentrated alcohol-based hand rubs (60-100%) cause less barrier disruption than washing with a basic detergent like SLS. The only measurable effect in these studies was a temporary dip in skin hydration.

Concentrations below 12-15% in leave-on cosmetics is generally well-tolerated. Concentrations above start to see increased transepidermal water loss (TEWL) and reduced hydration.

In concentrations about 58%, it creates temporary channels in your skin's lipid layers to become more permeable and allow other ingredients to slip through easily.

This ingredient can be up to 80% of the formula in alcohol-based perfumes.

Overall, this ingredient is probably harmless if found lower down an ingredients list but worth side-eyeing if it's high up (especially if your barrier is already struggling).

Alcohol can worsen dry skin, eczema, and oily skin, especially at higher concentrations. This is because it can increase transepidermal water loss and decrease hydration to disrupt the skin barrier.

According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.

True allergic contact dermatitis to ethanol is uncommon, but be sure to patch test if you have dry or sensitive skin.

Learn more about Alcohol
Cosmetic Colorant, UV Absorber, UV Filter

Titanium Dioxide (TD) is a mineral UV filter widely used in sunscreens and cosmetics.

It's one of only two UV filters officially classified as "mineral" by regulatory agencies (the other being Zinc Oxide).

A really common myth is that mineral filters work by reflecting UV light off your skin like tiny mirrors.

They don't only do that; modern research shows TD protects mostly by absorbing UV radiation, the same way chemical filters do.

When researchers measured this, reflection accounted for only about 4-5% of the protection (and less than SPF 2 on its own). The other ~95% comes from absorption: the UV photons hit the particle and their energy gets soaked up by its semiconductor band gap rather than bouncing off.

So "reflects vs. absorbs" was never really the right way to split mineral from chemical filters.

TD gives broad-spectrum protection that's strongest in the UVB and UVA-2 range and weaker in the UVA-1 range. Its UVA protection isn't quite as strong as Zinc Oxide's which is why you'll often see the two paired together.

Together, they make a solid broad-spectrum system.

TD is a great pick for sensitive, acne-prone, or redness-prone skin because it's non-irritating and chemically inert. Regulatory reviews classify it as a non-sensitizer and mild-to-non-irritant.

It's also unlikely to cause the "eye sting" some chemical filters are known for.

The main trade-off is cosmetic; TD can leave a white cast and has a thicker texture. This is why mineral sunscreens are often less cosmetically elegant than chemical or hybrid formulas (and harder to shade-match on deeper skin tones).

Formulators often use micronized or nano-sized TD to cut down on white case and improve spreadability. Smaller particles scatter less visible light so the formula looks less chalky while still filtering UV.

TD is almost always bundled with coatings like Alumina, Silica, Stearic Acid, or Dimethicone. These coatings do two important jobs:

TD can be used at up to 25% in a finished sunscreen; this is the regulatory ceiling in both the US and the EU.

In practice, the amount in any given product varies a lot depending on the target SPF and whether it's paired with other UV filters.

TD is one of the most heavily vetted sunscreen ingredients out there. It is approved as a UV filter in all major markets worldwide, including the US, EU, UK, Japan, Korea, China, Australia, and Canada.

The safety evidence is solid. There was an old worry that nano particles might absorb through skin into the body but multiple studies (including on damaged, sunburned, and UV-irradiated skin) have shown that TD stays on the surface and the layer of dead skin cells on top of everything else.

There's also no evidence of carcinogenicity, mutagenicity, or reproductive toxicity from dermal exposure of this ingredient.

For those who have seen the headline about a 2022 EU ban on TD, that was on TD as a food additive (a complete separate use from topical sunscreen).

There are ongoing questions about how nano-TD might affect marine ecosystems. As of now, there has been no conclusive evidence that any form of TD (or any other sunscreen filter) harms coral reefs or marine life.

The science is still developing and it's a space worth watching rather than packing over.

However, several destinations have reef-safety sunscreen rules that restrict certain chemical filters and steer visitors toward mineral, non-nano options. If you're traveling somewhere with these rules, a non-nano mineral sunscreen is the safe bet.

Learn more about Titanium Dioxide
Skin Conditioning

Phospholipids are a family of skin-identical lipids that makeup the structural backbone of every cell membrane in your body.

In cosmetics, they function as skin conditioning agents with emulsifier and surfactant properties. They're typically sourced from soybean or sunflower lecithin (or sometimes egg yolk or marine sources).

Because they mirror the lipids naturally found in the deeper layers of your skin, topical phospholipids help reinforce the lipid matrix, reduce transepidermal water loss, and leave skin feeling conditioned.

They're also used to form liposomes, or tiny self-assembling vesible used to stabilize actives like vitamin c or retinol. This helps these ingredients integrate into the upper layers of skin more easily.

Phospholipids are compatible with everything and the CIR Expert Panel has concluded them to be safe at current use levels.

Some types of phospholipids include:

Learn more about Phospholipids

We don't have a description for Broussonetia Kazinoki Root Extract yet.

Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Cleansing, Masking, Perfuming

This ingredient is also known as lime essential oil or key lime essential oil.

Like other citrus extracts and oils, this ingredient contains furanocoumarins that can cause phototoxicity.

Skin Conditioning

Orange Roughy Oil is an oil.

Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Learn more about Lecithin
Skin Conditioning

Pyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.

The sugar in Apples are humectants and help hydrate the skin. On top of that, apples also contain some acids, such as malic acid. These acids may have a mild exfoliating effect.

Last, the phytochemicals found in apples are strong antioxidants. These antioxidants help with anti-aging as they protect your skin cells against oxidative damage.

Learn more about Pyrus Malus Fruit Extract
Skin Conditioning

We don't have a description for Morus Alba Bark Extract yet.

Skin Conditioning

Camellia Japonica Leaf Extract comes from the leaves of the Camellia japonica plant. This plant is native to East Asia.

The leaves of Camellia Japonica have been found to have anti-inflammatory compounds. These include squalene, lupeol, and vitamin E.

This extract is created by using 50% 1,3-Butylene glycol.

Learn more about Camellia Japonica Leaf Extract
Cleansing, Skin Conditioning, Smoothing

Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier.

That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid.

These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.

Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.

Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.

Here is the short version of what they do in the skin:

So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.

Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:

Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.

Centella is one of the most easygoing actives out there.

It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.

On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.

Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.

But as with any new active, a patch test is still a smart move for very reactive skin.

Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).

The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).

In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.

Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Extract
Antimicrobial, Antioxidant, Astringent

Camellia Sinensis Leaf Extract (tea extract) is one of the most well-researched plant extracts in skincare with an impressive resume.

Black tea, green tea, and oolong tea are all harvested from the Camellia Sinensis plant.

Studies show green tea extract and its catechins (like epigallocatechin gallate (EGCG)) help your skin cells product energy more efficiently and reducing the number of free-radicals that can damage your skin from the inside.

In lab-grown skin models, this translated to younger, healthier, and stronger skin.

There's also good sun protection data; researchers saw less DNA damage and redness on human skin when green tea was applied before UVB exposure. And the more they applied, the better the protection.

Needless to say, this ingredient shouldn't replace your sunscreen. But it is a great supportive ingredient that you can already find in many sunscreens and antioxidant serums.

A 2009 study found a 2% green tea lotion was effective for mild-to-moderate acne thanks to its anti-inflammatory and mild antimicrobial activity.

The quality of the extract matters a lot here:

Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing. We recommend reaching out to the brand if you have questions about the quality or source of their ingredients.

Human Repeated Insult Patch Testing showed no irritation or sensitization at use concentrations (0.86% in leave-on products and up to 30% as leaf water).

Learn more about Camellia Sinensis Leaf Extract

We don't have a description for Garcinia Mangostana Peel Extract yet.

Buffering, Masking

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Read more about some other popular AHA's here:

Learn more about Citric Acid
Skin Conditioning

We don't have a description for Tricholoma Matsutake Extract yet.

Antioxidant, Bleaching, Skin Conditioning

Arbutin is a naturally occurring molecule (found in bearberry, cranberry, and blueberry) that is used in skincare as a gentle brightening agent to fade dark spots, melasma, and post-inflammatory hyperpigmentation.

Chemically, it is a sugar-bound form of hydroquinone.

It works mainly by inhibiting tyrosinase, the enzyme your skin uses to make melanin. This means less new pigment gets produced over time.

There are two forms you'll see on labels: beta-arbutin (listed as just "Arbutin") and alpha-arbutin (the more stable and effective of the two).

The evidence behind this is solid: it's less cytotoxic to melanocytes than hydroquinone and comparably effective with kojic acid for hyperpigmentation.

One human study using a 10% solution reduced UVR-induced hyperpigmentation by 43.5% (jumping to 63.3% when paired with aloesin).

More recent clinical work backs it up too; a 2025 study on a 5% alpha-arbutin + 2% kojic acid cream found it comparable to triple combination prescription formulas but with lower recurrence for melasma.

Typical usage in cosmetics serums land in the 1-2% range.

It's a well-tolerated, non-irritating, and non-photoreactive ingredient that also gives some antioxidant benefits too.

Learn more about Arbutin
Abrasive, Absorbent

Hydrated Silica is a type of silicon dioxide. It is called 'hydrated silica' because it is silica with extra bonded water atoms.

It is an absorbent and abrasive, meaning it is exfoliating.

Silica is often used for absorption and can help reduce shine when products are applied.

Learn more about Hydrated Silica
Antioxidant, Skin Protecting

Eucommia Ulmoides Bark Extract is an antioxidant.

Skin Conditioning

Bromelain is a proteolytic enzyme derived from pineapple stem. It gently exfoliates by by dissolving the "glue" holding dead skin cells to your skin's surface.

By faciliating the removal of dead skin cells from the outermost layer of skin, it helps with enhancing skin firmness, hydration, and texture.

Besides exfoliation, it also has anti-inflammatory properties by blocking the inflammation signaling pathways.

It is considered gentler than traditional AHAs or physical scrubs and is a great option for sensitive skin. At this time, most of the clinical trial data on enzyme exfoliants is still limited and further in vivo research is needed.

Typical concentrations for this ingredient range between 0.1-5%.

Bromelain's use in cosmetic formulations has been limited by its sensitivity to pH and temperature (it maintains best stability at pH 5.0). This means how effective is it in a finished product can vary depending on how well the formula is designed.

Learn more about Bromelain

This ingredient is also known as arabinogalactan. It is a polysaccharide extracted from North American larch trees. It is a film-forming agent that helps enhance skin hydration and improves the texture of products.

Once applied, galactoarabinan forms a lightweight and breathable film on the skin. This helps reduce transepidermal water loss (TEWL) without adding a greasy finish.

It is also used to boost the efficacy of exfoliating actives like AHAs by improving skin feel and reducing irritation potential.

Studies show this ingredient supports hydration through two actions:

1) Limiting water evaporation
2) Enhancing the spreadability of emulsion products to disperse humectants and emollients across the skin's surface

Additionally, galactoarabinan can improve makeup wear and reduce "tightness" after cleansing.

Learn more about Galactoarabinan
Humectant

Glucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.

Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.

It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.

Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.

Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.

In skincare, glucose is typically derived from corn or other starch sources.

Learn more about Glucose
Emollient, Humectant, Skin Protecting

Aluminum Hydroxide is a form of aluminum. It can be naturally found in nature as the mineral gibbsite. In cosmetics, Aluminum Hydroxide is used as a colorant, pH adjuster, and absorbent.

As a colorant, Aluminum Hydroxide may add opacity, or reduce the transparency. Aluminum hydroxide is contains both basic and acidic properties.

According to manufacturers, this ingredient is an emollient and humectant. This means it helps hydrate the skin.

In medicine, this ingredient is used to help relieve heartburn and help heal ulcers.

There is currently no credible scientific evidence linking aluminum hydroxide in cosmetics to increased cancer risk.

Major health organizations allow the use of aluminum hydroxide in personal care products and have not flagged it as a carcinogenic risk at typical usage levels.

Learn more about Aluminum Hydroxide
Emollient, Skin Conditioning

Hydrolyzed pea protein has skin conditioning and emollient properties. It is created by cutting protein fragments (peptides) into smaller pieces.

According to a manufacturer, this size of this ingredient makes it easy to be absorbed into skin where they strengthen the skin barrier, improve moisture retention, and improve signs of irritation.

One study that included pea proteins in a topical product reported improved atopic dermatitis symptom scores while a patent containing this ingredient suggests this ingredient to support hydration-related pathways in the skin.

Learn more about Hydrolyzed Pea Protein
Antioxidant, Skin Conditioning

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Learn more about Tocopheryl Acetate
Masking

Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.

You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.

You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.

You might see this ingredient used in scrubs as a primary exfoliating ingredient.

Learn more about Sodium Chloride
Emollient, Skin Conditioning

Methicone is a type of silicone and is a simpler form of dimethicone.

Silicones are used to enhance the texture of products and have emollient properties. Methicone is used to give products a silky texture and improves spreadability.

Glutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.

As an antioxidant, it prevents oxidative damage to parts of our cell.

While glutathione is said to help with fading dark spots, the results from research are inconclusive. Further studies are needed. With that said, gluthatione has been shown to protect our skin from UV-B induced damage.

This ingredient is naturally occurring in plants, animals, fungi, and some bacteria.

Learn more about Glutathione
Skin Conditioning

Gluconolactone is a PHA. PHAs are a great gentle alternative to traditional AHAs.

When applied, Gluconolactone has the same affect on skin as AHAs such as lactic acid. It helps dissolve the dead skin cells in the top layer of your skin. This improves texture and brightens the skin.

PHAs are more gentle than AHAs due to their larger structure. They do not penetrate as deeply as AHAs and take a longer time to dissolve dead cells. Studies show PHAs do not cause as much irritation.

Gluconolactone has some interesting properties:

In a 2004 study, Gluconolactone was found to prevent UV damage in mouse skin cells and has not been found to increase sun sensitivity. However, we still recommend wearing SPF daily.

This ingredient is is an created by reacting gluconic acid with an alcohol.

Learn more about Gluconolactone
Cleansing, Emollient, Skin Conditioning

Linoleic Acid is also known as Vitamin F. It is a fatty acid with emollient and skin conditioning properties.

Our top layer of skin, or epidermis, naturally contains high amounts of linoleic acid.

Your body uses linoleic acid to build ceramides and prostaglandins. Ceramides keep your skin's barrier hydrated and strong while prosaglandins help control inflammation and healing.

Needless to say, linoleic acid is crucial for having a strong skin barrier.

One study found applying linoleic acid rich sunflower oil to be more effective at repairing the skin barrier than olive oil.

This ingredient can also help treat acne by softening sebum to prevent clogged pores. Another study found using 2.5% linoleic acid gel for 4 weeks showed a 25% reduction in small comedones.

Studies show it can also help lighten hyperpigmentation or sun spots by disrupting the melanin production process. It also helps your skin shed melanin pigment from your skin caused by UV exposure.

Due to its role in the production of the fatty acid prostaglandin, linoleic acid can also help reduce inflammation and support wound healing.

Fun fact: Linoleic acid is an essential fatty acid. This means our bodies cannot create it on its own and we need to get it through foods such as nuts and vegetable oils.

Just know this ingredient is not always fungal-acne safe because it is a long-chain fatty acid (with 18 carbon atoms) that directly feeds the Malassezia yeast responsible for fungal acne.

Learn more about Linoleic Acid
Cleansing, Emollient, Perfuming

Linolenic Acid is also known as "ALA" or alpha-linolenic acid. It is a key fatty acid.

Our skin uses this ingredient for maintaining a healthy skin barrier, regulating inflammation, and supporting keratinocyte function.

ALA is a great skin hydrator because it has the ability to restore lipids in our stratum corneum, or outermost layer of our skin; it also helps prevent transepidermal water loss.

This ingredient also helps soothe irritated skin by downregulating inflammation.

Chia seed oil is one of the highest natural sources of ALA. Research shows topical chia seed oil significantly improves skin hydration, reduces itch, and strengthens the barrier in both healthy and extremely dry skin.

Additionally, in-vivo and in-vitro studies show ALA exhibits antioxidant properties, reduces UV-induced inflammation, and supports wound healing.

Early research showed a fatty-acid deficiency in animals leads to abnormal skin barrier function. It is believed a deficiency in linolenic acid may be linked to skin disorders like eczema.

Fun fact: This ingredient is considered an essential fatty acid for humans. This means our bodies cannot naturally produce it and we must get it from food. Some foods rich in linolenic acid include walnuts, fish oils, soy, and canola.

Learn more about Linolenic Acid
Masking, Preservative

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Learn more about Sodium Benzoate
Buffering

We don't have a description for Sodium Succinate yet.

Antioxidant, Masking

Ascorbyl Palmitate is a fat-soluble form of vitamin C (Ascorbic Acid) made by combining it with palmitic acid.

It is able to blend easily into creams and oil-based formulas because it dissolves in oils rather than water.

As you may know, regular vitamin C is notorious for breaking down when exposed to sunlight and air. Ascorbyl Palmitate is more stable and degrades at a slower rate.

Research on whether it converts efficiently into active vitamin C once it's applied on your skin is still limited.

Some in-vitro studies suggest it may support collagen production, but it is not considered one of the stronger vitamin C derivatives, like:

Due to the palmitic acid base, this ingredient may not be fungal acne safe. Comedogenic studies have also shown this ingredient to have a rating of 2.

It's also worth keeping in mind that comedogenic and irritancy ratings are tested on individual ingredients, not finished formulas. The final product's formulation, concentration, and other ingredients all play a role in how something actually behaves on your skin.

Learn more about Ascorbyl Palmitate
Humectant, Skin Conditioning

This ingredient is calcium salt of gluconic acid. It is a humectant, meaning it attracts water to your skin.

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Where it's from

Panah Labs is a British brand

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50 SPF Rating

With an SPF rating of 50, this product protects against 98.0% of UVB rays

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· Updated January 7, 2025 Added by jnm