Mary & May Spicule Retinol PDRN Cream
A night moisturizer with 52 ingredients, including retinoid, niacinamide, and vitamin E.
Overview
What it is
Night moisturizer with 52 ingredients that contains ceramides, hyaluronic acid, niacinamide, retinoid and Vitamin E
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, parabens or sulfates
Fun facts
Mary & May is from South Korea.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningMethylpropanediol
SolventGlycerin
Humectant1,2-Hexanediol
Skin ConditioningNiacinamide
SmoothingPanthenol
Skin ConditioningCaprylic/Capric Triglyceride
MaskingPolypropylsilsesquioxane
C14-22 Alcohols
Emulsion StabilisingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Glyceryl Stearate
EmollientCetyl Ethylhexanoate
EmollientVinyldimethicone
Macadamia Ternifolia Seed Oil
EmollientBrassica Campestris Sterols
EmollientPolyglyceryl-10 Laurate
Skin ConditioningAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingC12-20 Alkyl Glucoside
EmulsifyingArginine
MaskingPhytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Skin ConditioningCholesterol
EmollientSodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingHydrolyzed Sponge
Skin ConditioningPolyisobutene
Gardenia Florida Fruit Extract
Skin ConditioningTocopherol
AntioxidantAllantoin
Skin ConditioningEthylhexylglycerin
Skin ConditioningButyrospermum Parkii Butter
Skin ConditioningRetinol
Skin ConditioningXanthan Gum
EmulsifyingHydrogenated Lecithin
EmulsifyingSodium Hyaluronate
HumectantPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantAdenosine
Skin ConditioningDextrin
AbsorbentHelianthus Annuus Seed Oil
EmollientLauryl Glucoside
CleansingPolyglutamic Acid
Skin ConditioningPolyglyceryl-6 Laurate
EmulsifyingDisodium EDTA
Ceramide NP
Skin ConditioningCaprylyl/Capryl Glucoside
CleansingSorbitan Oleate
EmulsifyingMyristyl Glucoside
CleansingStearic Acid
CleansingBenzotriazolyl Dodecyl P-Cresol
UV AbsorberGlyceryl Acrylate/Acrylic Acid Copolymer
HumectantOleic Acid
EmollientPvm/Ma Copolymer
Emulsion StabilisingBeta-Carotene
Skin ConditioningSodium Dna
Skin ConditioningWater, Methylpropanediol, Glycerin, 1,2-Hexanediol, Niacinamide, Panthenol, Caprylic/Capric Triglyceride, Polypropylsilsesquioxane, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Glyceryl Stearate, Cetyl Ethylhexanoate, Vinyldimethicone, Macadamia Ternifolia Seed Oil, Brassica Campestris Sterols, Polyglyceryl-10 Laurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12-20 Alkyl Glucoside, Arginine, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Cholesterol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrolyzed Sponge, Polyisobutene, Gardenia Florida Fruit Extract, Tocopherol, Allantoin, Ethylhexylglycerin, Butyrospermum Parkii Butter, Retinol, Xanthan Gum, Hydrogenated Lecithin, Sodium Hyaluronate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Adenosine, Dextrin, Helianthus Annuus Seed Oil, Lauryl Glucoside, Polyglutamic Acid, Polyglyceryl-6 Laurate, Disodium EDTA, Ceramide NP, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Myristyl Glucoside, Stearic Acid, Benzotriazolyl Dodecyl P-Cresol, Glyceryl Acrylate/Acrylic Acid Copolymer, Oleic Acid, Pvm/Ma Copolymer, Beta-Carotene, Sodium Dna
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterMethylpropanediol is a synthetic solvent and humectant.
As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.
Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.
Learn more about MethylpropanediolGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about Glycerin1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamidePanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolThis ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglyceridePolypropylsilsesquioxane is a type of silicone.
C14-22 Alcohols is made up of synthetic fatty alcohols. More specifically, these fatty alcohols contain 14 to 22 carbons in the alkyl chain.
Its main purpose is to stabilize products. As an emulsifier, it helps prevent waters and oils from separating.
Ammonium Acryloyldimethyltaurate/Vp Copolymer (let's call it AAVC for short) is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
AAVC is able to increase the consistency and viscosity of products due to its large molecule size. It also prevents ingredients from separating.
Glyceryl Stearate is a mix of glycerin and stearic acid.
It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.
As an emollient, it helps soften skin and supports barrier-replenishing ingredients.
In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.
This ingredient may not be fungal-acne safe
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateCetyl Ethylhexanoate is an emollient ester. It comes from cetearyl alcohol and 2-ethylhexanoic acid.
Cetyl Ethylhexanoate is an emollient that adds a velvety feel to skin without being greasy or oily. Emollients help trap moisture into your skin, keeping your skin soft and hydrated.
Vinyldimethicone is a type of silicone.
Macadamia Ternifolia Seed Oil is the fixed oil obtained from Macadamia nut.
Macadamia seed oil is rich in fatty acids, including oleic acid (45-75%), palmitoleic acid (7-33%), and palmitic acid (6-12%). They also contain various B vitamins, iron, and magnesium.
Palmitoleic acid has been shown to help soothe inflammation and promote wound healing. It is also naturally found in the fat of our skin.
Macadamia seed oil may not be malassezia folliculitis, or fungal-acne, safe.
Learn more about Macadamia Ternifolia Seed OilBrassica Campestris Sterols isn't fungal acne safe.
Polyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.
Polyglyceryl-10 Laurate is a cleansing agent and emulsifier. It helps gather dirt, oil, and other pollutants to be rinsed away. As an emulsifier, it helps prevent ingredients from separating, such as oil and water.
Polyglyceryl-10 Laurate may not be fungal acne safe.
Learn more about Polyglyceryl-10 LaurateAcrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products. Due to its properties, it can prevent water and oil ingredients from separating.
We don't have a description for C12-20 Alkyl Glucoside yet.
Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.
As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.
Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.
Learn more about ArginineWe don't have a description for Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate yet.
Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.
Our skin naturally contains cholesterol in the outermost layer. Besides cholesterol, it also contains ceramides and fatty acids. Cholesterol makes up about 1/4 of your skin's outer layer and barrier. Your skin barrier is responsible for keeping allergens and microbes out. Having a healthy skin barrier is also responsible for keeping your skin firm and plump.
Our bodies use cholestrol to create vitamin D, steroid hormones, and more.
Learn more about CholesterolThis long ingredient is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate monomers.
It is used to help stabilize other ingredients and create a thicker gel-like texture.
Emulsifiers prevent oils and waters from separating.
Learn more about Sodium Acrylate/Sodium Acryloyldimethyl Taurate CopolymerHydrolyzed sponge comes from marine or freshwater sponges. This is the main ingredient for "spicules".
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. They help push active ingredients into the skin to enhance the penetration and efficacy of these ingredients.
Polyisobutene is a synthetic polymer made from isobutene.
It is a film-forming agent and helps bind ingredients together.
Polyisobutene is not absorbed by the skin.
Learn more about PolyisobuteneWe don't have a description for Gardenia Florida Fruit Extract yet.
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolAllantoin is a soothing ingredient known for its protective and moisturizingg properties. Because of this, it is often added to products with strong active ingredients.
Studies show higher concentrations of this ingredient can promote wound healing.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Learn more about AllantoinEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
This ingredient is also known as shea butter. It is an effective skin hydrator and emollient.
Emollients help soothe and soften your skin. It does this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.
Shea butter is rich in antioxidants. Antioxidants help fight free-radicals, or molecules that may harm the body. It is also full of fatty acids including stearic acid and linoleic acid. These acids help replenish the skin and keep skin moisturized.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
Shea butter may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.
Learn more about Butyrospermum Parkii ButterRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumHydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.
This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronatePentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.
It is used to help stabilize other antioxidants or prevent the color from changing in a product.
As an antioxidant, it helps fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Thus, antioxidants may reduce the signs of aging.
This ingredient is oil-soluble.
Learn more about Pentaerythrityl Tetra-Di-T-Butyl HydroxyhydrocinnamateAdenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineDextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.
As an emulsifier, dextrin prevents ingredients from separating. This helps elongate a product's shelf life.
Studies show coating UV filters with dextrin prevents these ingredients from being absorbed. This helps UV ingredients last longer on the skin.
Learn more about DextrinHelianthus Annuus Seed Oil is the oil derived from the seeds of a Sunflower. Sunflower seed oil is non-fragrant. It is an emollient, meaning it helps to soften the skin.
Sunflower seed oil contains many fatty acids. The fatty acids found in sunflower seeds include (from highest amount to least): linoleic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, and linolenic acid.
These fatty acids help the skin create ceramides. Ceramides play a role in repairing the skin barrier.
Helianthus Annuus Seed Oil helps moisturize the skin. This in turn helps the skin look more rejuvenated and smoother.
Sunflowers are rich in vitamin E.
Historians believe Indigenous cultures of North America domesticated sunflowers before corn. Thus they relied on sunflower oil for a variety of uses. One such use is moisturizing skin and hair.
Sunflower seed oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.
Learn more about Helianthus Annuus Seed OilLauryl Glucoside sugar- and lipid-based cleansing agent. It is created from glucose and lauryl alcohol.
This ingredient is a surfactant, making it easier to rinse oil, dirt, and other pollutants away.
A British study found lauryl glucoside to cause skin sensitivity for some people. We recommend speaking with a professional if you have concerns.
Other names for this ingredient include "Lauryl Polyglucose", "Lauryl glycoside", and "D-Glucopyranoside".
Learn more about Lauryl GlucosidePolyglutamic Acid is made up many glutamic acids chained together. It is created from bacterial fermentation.
This ingredient is an effective skin hydrator and may help speed up wound healing. As a humectant, it draws and holds water to the skin. This ingredient is often compared to hyaluronic acid or glycerin. Similarly to hyaluronic acid, it can vary in molecular weights. This means polyglutamic acid is capable of bringing hydration to lower levels of the skin.
Fun fact: Polyglutamic Acid is found in the Japanese food, natto. It is also being used in cancer treatment studies.
Learn more about Polyglutamic AcidPolyglyceryl-6 Laurate isn't fungal acne safe.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTACeramide NP is a type of ceramide.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Ceramide AP
Ceramide EOP
Caprylyl/Capryl Glucoside is an alkyl glucoside. This just means it is creating by reacting alcohol and sugar. It is a cleansing and foaming ingredient.
Caprylyl/Capryl Glucoside helps remove the dirt, oil, and other pollutants from your skin.
Sorbitan Oleate is created from compounds in oleic acid and sorbitol.
It is used to stabilize a product by preventing ingredients from separating. Emulsifiers help keep ingredients together, such as oils and water.
According to a manufacturer, the ingredient Sorbitan Monooleate shares an INCI name with this one.
Sorbitan Oleate may not be fungal acne safe. It can also worsen oily skin.
Learn more about Sorbitan OleateWe don't have a description for Myristyl Glucoside yet.
Stearic Acid is a fatty acid. It is an emollient, emulsifier, and texture enhancer.
As an emollient, stearic acid helps soften skin. It aids the skin's protective barrier by preventing water loss. It also provides a gentle cleansing effect without stripping away natural oils.
Stearic acid may also be used to enhance the texture of products. It can add volume and stabilize ingredients such as water and oil. This can help water and oil ingredients from separating.
Sources of stearic acid include animal or vegetable fats/oils such as coconut or shea. It can be naturally found in butter, cocoa butter, shea butter, vegetable fats, and animal tallow.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe.
Learn more about Stearic AcidBenzotriazolyl Dodecyl P-Cresol, also known as Tinogard TL, is a broad-spectrum UV absorber.
It helps stabilize light-sensitive ingredients and protects other ingredients from breaking down due to light exposure (especially in transparent packaging).
This ingredient helps extend a product’s shelf life by preventing both photolytic (light-induced) and photo-oxidative degradation. It’s typically used at low concentrations, around 0.01% to 0.1%.
Despite being a chemical UV filter, this ingredient can be found in "100% mineral sunscreens". This is due to regulatory loopholes.
Learn more about Benzotriazolyl Dodecyl P-CresolGlyceryl Acrylate/Acrylic Acid Copolymer is made up of glycerin and polyacrylic acid. It helps hydrate your skin as a humectant.
This ingredient forms a hydrogel that delivers moisturizing, water-based ingredients to the skin. It is also used to thicken a product and to give it a smooth texture.
Acrylic acid itself is toxic, but the polymer form (this ingredient) is too large to penetrate skin, making it non-toxic.
Learn more about Glyceryl Acrylate/Acrylic Acid CopolymerOleic Acid is an Omega-9 fatty acid. It can be found in many plant oils such as avocado and marula oils.
This ingredient is used to enhance the texture of products and as a cleansing agent.
Oleic Acid may not be fungal acne safe.
Learn more about Oleic AcidWe don't have a description for Pvm/Ma Copolymer yet.
Beta-Carotene is a carotenoid. It is an antioxidant that converts to Vitamin A. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
It gives plants the red, orange, and yellow color. Some foods with Beta-Carotene include sweet potatoes, carrots, apricots, and cantaloupe.
Sodium DNA is an emerging anti-aging ingredient.
It is created by taking deoxyribonucleic acid (DNA) and purifying it with sodium hydroxide.
The DNA is extracted from several different animal sources, including: calf thymus, the gonadic tissue of a male sturgeon, or herring / salmon sperm.
You have probably seen this ingredient in anti-aging skincare. But what is it?
DNA is composed of nucleotides, or chemical building blocks. Nucleotides include adenine (A), thymine (T), guanine (G), and cytosine (C). Talk about a flashback to biology! Nucleosides are formed from these nucleotides.
The science behind Sodium DNA is based on an ingredient called Polydeoxyribonucleotide or PDRN.
PDRN are DNA fragments mainly extracted from the sperm cells of trout or salmon. Meaning, PDRN can be derived from Sodium DNA.
PDRN consists of chains of nucleotides and nucleosides mentioned above. They can range anywhere from 80 - 2000 pairs.
Studies show PDRN has the following properties:
Most of the research on PDRN has been done using injectable forms. That’s important, because PDRN is a large molecule and doesn’t absorb well through the skin. So if you’re applying it topically, the effects are likely to be much milder.
Still, topical Sodium DNA is emerging as a trendy anti-aging ingredient. It’s generally well-tolerated and offers good biocompatibility with human skin, making it a low-risk addition to most routines.
Further studies are needed to truly confirm this ingredients anti-aging ability (Remember, retinol has decades of research!).
When using this ingredient, is is best to ask a brand about the source of their Sodium DNA. You'll want to find products where the Sodium DNA is sourced from fish. Some Sodium DNA is derived from calf / cow thymus.
Needless to say, this ingredient is not vegan.
Learn more about Sodium DnaReviews
No written reviews yet. Be the first to review this product.
Where it's from
Mary & May is a Korean brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated November 16, 2025 • Added by amandaboss