Dear My:Dew Hycica Soothing Gentle Cleansing Foam
A face cleanser with 47 ingredients, including hyaluronic acid and ceramides.
This mild cream cleanser is made to cleanse while calming and soothing your skin.
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantSodium Cocoyl Isethionate
CleansingCoco-Betaine
CleansingStearyl Alcohol
EmollientGlyceryl Stearate
EmollientHydroxypropyl Starch Phosphate
Glycol Distearate
EmollientLauryl Hydroxysultaine
CleansingSodium Methyl Cocoyl Taurate
CleansingCoco-Glucoside
CleansingSodium Chloride
Masking1,2-Hexanediol
Skin ConditioningCaprylyl Glycol
EmollientEthylhexylglycerin
Skin ConditioningRosmarinus Officinalis Leaf Oil
MaskingCitric Acid
BufferingSodium Phytate
Butylene Glycol
HumectantAllantoin
Skin ConditioningPanthenol
Skin ConditioningSodium Hyaluronate
HumectantCaprylic/Capric Triglyceride
MaskingAloe Barbadensis Leaf Extract
EmollientHydrogenated Lecithin
EmulsifyingPolyglyceryl-10 Myristate
Skin ConditioningCentella Asiatica Root Extract
Skin ConditioningCentella Asiatica Leaf Extract
Skin ConditioningCentella Asiatica Extract
CleansingSaccharomyces Ferment
Skin ConditioningCeramide NP
Skin ConditioningSucrose Distearate
EmollientBeta-Glucan
Skin ConditioningLauric Acid
CleansingPhytosterols
Skin ConditioningTrehalose
HumectantHydroxypropyltrimonium Hyaluronate
Asiaticoside
AntioxidantMadecassoside
AntioxidantSodium Acetylated Hyaluronate
HumectantHydrolyzed Hyaluronic Acid
HumectantSodium Hyaluronate Crosspolymer
HumectantHydrolyzed Sodium Hyaluronate
Skin ConditioningHyaluronic Acid
HumectantPotassium Hyaluronate
Skin ConditioningMadecassic Acid
Skin ConditioningAsiatic Acid
Skin ConditioningWater, Glycerin, Sodium Cocoyl Isethionate, Coco-Betaine, Stearyl Alcohol, Glyceryl Stearate, Hydroxypropyl Starch Phosphate, Glycol Distearate, Lauryl Hydroxysultaine, Sodium Methyl Cocoyl Taurate, Coco-Glucoside, Sodium Chloride, 1,2-Hexanediol, Caprylyl Glycol, Ethylhexylglycerin, Rosmarinus Officinalis Leaf Oil, Citric Acid, Sodium Phytate, Butylene Glycol, Allantoin, Panthenol, Sodium Hyaluronate, Caprylic/Capric Triglyceride, Aloe Barbadensis Leaf Extract, Hydrogenated Lecithin, Polyglyceryl-10 Myristate, Centella Asiatica Root Extract, Centella Asiatica Leaf Extract, Centella Asiatica Extract, Saccharomyces Ferment, Ceramide NP, Sucrose Distearate, Beta-Glucan, Lauric Acid, Phytosterols, Trehalose, Hydroxypropyltrimonium Hyaluronate, Asiaticoside, Madecassoside, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Potassium Hyaluronate, Madecassic Acid, Asiatic Acid
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinSodium cocoyl isethionate is a natural ingredient from coconut oil. It is an ultra gentle cleanser that gives a nice foam without drying the skin or impacting the skin barrier.
The amount of foam created depends on the amount of sodium cocoyl isethionate used in the product.
This ingredient also helps improve the spreadability of a product.
This ingredient hasn’t been shown in studies to feed fungal acne yeast.
Learn more about Sodium Cocoyl IsethionateCoco-Betaine is the natural version of Cocamidopropyl Betaine. It is often derived from coconuts.
Coco-Betaine is a surfactant, meaning it helps remove dirt and oil from the skin.
Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients used as an emollient or to thicken a product.
Emollients help soothe and hydrate the skin by trapping moisture.
Fatty alcohols are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent (ethanol) alcohols.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Learn more about Stearyl AlcoholGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateHydroxypropyl Starch Phosphate is a modified starch used to help thicken a product.
It is also used in foods.
Glycol Distearate is an emulsifier and emollient that adds a "pearly" appearance to formulations.
That lustrous look you see in many shampoos is due to this ingredient: when cooled, it crystallizes into small platelets that reflect light to give products that rich, shimmering look.
This ingredient is considered safe at present practices of use and concentration and repeated insult patch test with 50% Glycol Distearate on 125 subjects found no evidence of skin irritation, hypersensitivity, or acute toxicity.
Typical use concentrations range from 0.1-10%.
Because it's an ester of stearic acid, it falls into the range that Malassezia likes to metabolize. This ingredient may not be fungal acne safe.
Learn more about Glycol DistearateLauryl Hydroxysultaine is a mild surfactant or cleansing ingredient that helps lift away dirt/oil, boost foam, and thicken the formula. It plays nicely with other surfactants and stays stable across a wide pH range.
Sodium Methyl Cocoyl Taurate is a gentle, coconut-derived cleansing surfactant. It's most commonly found in "sulfate-free" cleansers.
As a taurate, it belongs to a class of anionic surfactants prized for being efficient at cleansing without harshness, good performance in hard water, stability across a wide pH range, and easily biodegradable.
It is able to lift away oil and grime and make a nice lather without stripping your skin, so it's a good pick for sensitive skin.
Safety-wise, it has a good record. The CIR Expert Panel has concluded this ingredient to be safe in cosmetics and concentrations go up to 11% in leave-on products or 13% in rinse-off products.
Despite being derived from coconut oil, this ingredient is fungal acne safe. It's a water-soluble surfactant with no fatty oils or esters left intact on skin for the Malassezia yeast to feed.
Learn more about Sodium Methyl Cocoyl TaurateCoco-Glucoside is a surfactant, or a cleansing ingredient. It is made from glucose and coconut oil.
Surfactants help gather dirt, oil, and other pollutants from your skin to be rinsed away.
This ingredient is considered gentle and non-comedogenic. However, it may still be irritating for some.
Learn more about Coco-GlucosideChances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.
You might see this ingredient used in scrubs as a primary exfoliating ingredient.
Learn more about Sodium Chloride1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinRosmarinus Officinalis Leaf Oil is an essential oil also known as rosemary essential oil. In skincare, it is a skin conditioning agent and also acts as a natural fragrance that gives products a fresh/herby smell.
The oil is a mix of over 100 volatile compounds with 1,8-cineole, α-pinene, camphor, and verbenone usually leading the pack.
Lab studies credit this oil with antioxidant, anti-inflammatory, and antimicrobial activity. Some research even show rosemary compounds calming acne-related inflammation.
The Cosmetic Ingredient Review (CIR) has concluded rosemary-derived ingredients to be safe when formulated to be nonsensitizing.
Since this is a fragrant essential oil, the main concern is for fragrance-sensitive folks.
Learn more about Rosmarinus Officinalis Leaf OilCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidSodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideAloe Barbadensis Leaf Extract is a botanical extract pulled from the leaves of aloe vera and one of the most studied plant ingredients in cosmetics.
The inner leaf gel it comes from is mostly water (~99-99.5%) and the remaining fraction is made up of pretty good stuff: polysaccharides, vitamins, phenolics, and enzymes.
Its headline job is hydration.
The star polysaccharide in aloe, acemannan, is a humectant that retains moisture and helps reduce trans-epidermal water loss.
Aloe also has real soothing credentials; it contains anti-inflammatory compounds like bradykinase and C-glucosyl chromone that help calm irritation and redness.
On the repair side, lab work shows that acemannan wakes up your skin's repair cells (fibroblasts), prompting them to multiply and speed up healing.
There's some human data for cosmetic benefit too: a cream containing 10% Aloe Barbadensis leaf extract improved skin hydration and elasticity in a real-use study.
Safety-wise, this ingredient is well-regarded with just one rare downside; there have been some case reports of acute eczema, contact urticaria, and dermatitis in people who applied aloe-derived ingredients topically. Those with a known aloe or Liliaceae sensitivity should patch test.
Typical use levels range widely, from under 1% up to 90%+ depending on the format and the effect you are after.
Learn more about Aloe Barbadensis Leaf ExtractHydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Learn more about Hydrogenated LecithinPolyglyceryl-10 Myristate is a nonionic emulsifier and skin conditioner made from Polyglycerin-10 and Myristic Acid.
As a skin conditioning agent, this ingredient leaves skin feeling soft without a greasy finish. As an emulsifier, it helps stabilize oil-in-water emulsions.
You'll likely see this ingredient in "clean" formulations because it's considered a natural alternative to PEGs.
Patch testing at concentration 0.1-1% showed no reactions and this ingredient is considered to be well-tolerated across skin types.
Due to its myristic acid base, this ingredient may not be fungal acne safe.
Learn more about Polyglyceryl-10 MyristateCentella Asiatica Root Extract can be good for sensitive skin. It can help to reduce redness.
Centella Asiatica Leaf Extract comes from the leaves of an herb plant native to Southeast Asia. Centella Asiatica is rich in antioxidants and amino acids. It can help reduce irritation and soothe the skin.
Many active components found in centella asiatica, such as Madecassic Acid and Asiaticoside, encourage the skin to naturally produce hyaluronic acid. This helps keep our skin hydrated. Many of these components also show antioxidant activity and may help reduce the signs of aging.
Research shows centella asiatica can help increase Type I collagen production by increasing fibroblast production. Fibroblast helps form connective tissue.
The combination of all these properties makes centella asiatica leaf extract effective at soothing the skin.
Other components of centella asiatica leaf extract include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Recent studies found madecassoside may help prevent damage from UV rays by preventing UV-induced inflammation. Further research is needed.
This plant has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica Leaf ExtractCentella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier.
That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid.
These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.
Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.
Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.
Here is the short version of what they do in the skin:
So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.
Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:
Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.
Centella is one of the most easygoing actives out there.
It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.
On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.
Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.
But as with any new active, a patch test is still a smart move for very reactive skin.
Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).
The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).
In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.
Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractSaccharomyces Ferment is what you get when you ferment yeast from Saccharomyces genus and keep the ferment rather than just the strained liquid.
You can think of it like the water-like version of Saccharomyces Ferment Filtrate.
As yeast eats through its growth medium, it leaves behind a nutrient soup of amino acids, peptides, vitamins, and minerals.
The component with the most actual research behind it, beta-glucan, is a polysaccharide that acts as a barrier-supportive humectant with antioxidant and skin-soothing properties.
Typical use concentrations range from 1-3%.
Fungal acne: This ingredient may not be considered fungal-acne safe. Even though Saccharomyces isn't the same yeast as Malassezia, fermentation can produce fatty acids in the C11-24 range that Malassezia feeds on.
Learn more about Saccharomyces FermentCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPSucrose Distearate is made up of the sucrose (sugar) esthers of stearic acid. It is an emollient and emulsifier.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe.
Beta-Glucan is a soluble polysaccharide (a chain of glucose sugars) sourced from the cells walls of oats, baker's yeast, mushrooms, and seaweed.
It's a rare ingredient that pulls double-duty as a heavy-duty hydrator and skin-soothing repair agent.
On the surface, it acts as a humectant that holds water in place and reduces moisture loss for a plumper, smoother feel, while its anti-inflammatory and antioxidant properties make it a great pick for calming redness or sensitive skin
The more interesting story is underneath:
Despite its large molecular size, oat beta-glucan has been shown to penetrate the epidermis and reach the dermis by slipping between skin cells. Here, it interacts with fibroblasts and macrophages to nudge collagen synthesis and support wound repair.
A small 2005 split-face clinical study of 27 subjects found topical beta-glucan produced measurable reductions in wrinkle depth, height, and roughness after 8 weeks of use.
It is worth noting the trial was small and the penetration testing used frozen, irradiated skin so the anti-aging data is encouraging rather than definitive.
This ingredient gets along with pretty much everything and is typically used around 0.1-1%.
Fungal acne: This ingredient is not a food source for the Malassezia yeast because it is a glucose polysaccharide with no fatty acid or ester component.
Learn more about Beta-GlucanLauric Acid is a saturated fatty acid naturally found in coconut oil, palm kernel oil, and even breast milk.
In cosmetics, it is an:
Lab studies have found that lauric acid is surprisingly good at killing acne-causing bacteria. However, these tests were done on bacteria in a petri dish and not on real skin, so we can't say for certain it works the same in a formulation on a real face.
The comedogenic rating of 4 comes from the 1972 rabbit ear model using undiluted ingredients. Comedogenicity is highly individual and one comedogenic ingredient cannot predict how a formula will behave on skin.
This ingredient is not fungal acne safe and research has confirmed Malassezia can use it as a food source. Even though "fungal acne" has the word "acne" in it, they are completely different. Regular acne is driven by a bacteria called Cutibacterium acnes, clogged pores, and excess oil. Fungal acne isn't really acne; it's caused by an overgrowth of a yeast called Malassezia that already lives on everyone's skin. Because one is bacterial and the other is fungal, they respond to different ingredients.
Learn more about Lauric AcidPhytosterols are plant-derived sterols (you can think of them as the plant world's version of cholesterol). In cosmetics, this ingredient is usually sourced from soybean, rice bran, shea, sunflower, and other seed oils.
The main actors in this group are β-sitosterol, campesterol, and stigmasterol (the CIR covers 27 phytosterols).
They work by fitting perfectly into your stratum corneum's lipid matrix since they're structurally similar to cholesterol. Here, they reinforce your skin's barrier.
One small in vivo human study showed topical soybean phytosterols sped up barrier recovery within three days on tape-stripped skin.
Broader research credits them with:
Formulation use typically sit under 5%.
Testing in soy-allergic subjects found no sensitization signals, but be sure to patch test if you are unsure or have existing allergies.
Learn more about PhytosterolsTrehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.
As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.
Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.
In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.
Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.
Learn more about TrehaloseHydroxypropyltrimonium Hyaluronate is a positively charged version of hyaluronic acid.
This small change does a lot in a formula:
Regular hyaluronic acid carries a negative charge and so does the surface of your skin. This means the two repel each other and hyaluronic acid can be washed away easily. The positive charge here does the opposite: it makes the ingredient cling to your skin (also called "substantivity") so it keeps hydrating even in rinse-off products where it lays down a light, moisture-holding film.
The research backs this up too; a 2025 clinical study on a shower gel containing 0.1% positively charged hyaluronic acid increased skin hydration by 6.6% versus the baseline and 11.1% versus the placebo. This was measured 6 hours after 1 minute of contact and rinse, and on volunteers with very dry skin.
The same team's lab work showed it adhered to skin far better than unmodified hyaluronic acid (+107% vs. low molecular weight, +23% versus high molecular weight). They also found it increased two proteins tied to skin hydration, aquaporin-3 by 16% and filaggrin by 35%.
A separate 2024 study reached a similar conclusion and credited the hydrating benefits to its film-forming properties.
Both studies used the ingredient at 0.1% which also matches how much it usually shows up in products (at fractions of a percent).
One honesty note worth keeping in mind: the published research comes from the company that manufactures the ingredient so independent data would strengthen the picture. However, the results are consistent and the mechanism makes sense.
As a Hyaluronic Acid derivative, it has a well-tolerated profile and suits most skin types.
Learn more about Hydroxypropyltrimonium HyaluronateAsiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It's the reason centella-based products have a strong reputation for repairing and calming skin, along with its sibling compound Madecassoside.
Research from 2016-2025 supports its role in:
You'll usually find this in concentrations between 0.2-5%.
Learn more about AsiaticosideMadecassoside is one of four active compounds found in Centella asiatica and is one of the main reasons Centella is so effective at calming irritated skin and supporting the moisture barrier.
There's a solid body of peer-reviewed research backing Madecassoside for several skin benefits. Studies have found:
Madecassoside pairs well with other hydrating or antioxidant ingredients like Ascorbic Acid or Hyaluronic Acid.
Learn more about MadecassosideSodium Acetylated Hyaluronate is a type of Hyaluronic Acid.
Hyaluronic Acids help moisturize, soothe, and protect the skin.
Read about common types of Hyaluronic Acid here:
Learn more about Sodium Acetylated HyaluronateHydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.
It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.
Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.
Most formulations will combine all sizes to get the best of both worlds.
Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.
Learn more about Hydrolyzed Hyaluronic AcidSodium Hyaluronate Crosspolymer is a crosslinked version of sodium hyaluronate. This just means it's linked into a 3D mesh network that lets it be more stable and sit on skin as a cohesive, gel-like film rather than sinking into skin.
A 2016 human skin study found crosslinked HA increased epidermal water content by 7.6% over the control group and reduced transepidermal water loss by 27.8%.
A follow-up clinical trial found that a topical crosslinked HA serum applied after fillers, microneedling, or chemical peels was well-tolerated and enhanced skin quality at 14 / 28 days.
More recent research suggests that concentrations as low as 0.03% can act as a penetration enhancer for other skincare actives.
Learn more about Sodium Hyaluronate CrosspolymerThis ingredient is created by putting sodium hyaluronate through hydrolysis.
You might know this as 'mini' or 'ultra low-molecular weight' hyaluronic acid. The small molecule size means it is able to travel deeper in the skin.
According to studies, low molecular-weight hyaluronic acid can:
One study from 2011 found ultra-low weight HA to show pro-inflammatory properties. Another study from 2022 found it to downregulate UV-B induced inflammation.
Hydrolysis is a process of changing a molecule using water or enzymes.
This ingredient is water-soluble.
Learn more about Hydrolyzed Sodium HyaluronateHyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.
Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.
The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
This is why the best HA serums blend the two sizes together so you get the best of both worlds.
The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.
A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidPotassium hyaluronate (PH) is a salt form of hyaluronic acid and has similar skin hydrating benefits.
Similar to hyaluronic acid, PH is able to draw and hold moisture to your skin. This helps keep skin soft and hydrated.
Fun fact: PH is used in eye drops and injectable treatments for joint disorders. It has lubricating and tissue-repair properties.
Learn more about Potassium HyaluronateMadecassic Acid is one of the four star actives in Centella Asiatica. In skincare, it earns its keep as a calming and repairing ingredient.
It works through the same core pathways as the rest of the centella family.
First, it turns down inflammation so it helps with things like redness and general upset skin.
Second, it acts as an antioxidant which means it helps protect skin from daily stress and damage.
And third, it nudges the skin to make more collagen and rebuild its support structure.
That combination is why the whole Centella family is known for calming skin, strengthening the barrier, fading redness, and giving anti-aging benefits.
It's worth being honest about the evidence here; a lot of the strongest data is on the full extract or a Madecassoside/Asiaticoside rather than Madecassic Acid alone. Reviewers also note more long-term clinical trials are needed to confirm the full potential.
Concentration-wise, this ingredient is rarely used pure and usually shows up as part of a standardized centella extract where reported content ranges from 0.02-3.06%.
Finished products typically run somewhere in the 0.1-10% range depending on the format.
In real-world tolerance tests, a repeat-insult patch test on an eye lotion with 0.2% Centella extract showed no irritation or allergic contact dermatitis in 54 subjects. And a mascara with 0.5% Madecassoside caused neither irritation nor sensitization in 109 subjects.
Allergy risk is very low, but not zero. Centella and its constituents are classified as weak contact sensitizers and some rare cases of allergic contact dermatitis exist.
Learn more about Madecassic AcidAsiatic Acid is one of the four main actives found in Centella Asiatica. Its headline job is stimulating collagen.
Lab tests on human skin cells show Asiatic Acid tells your skin to make more collagen, the protein that keeps skin firm and bouncy.
It also calms inflammation and acts as an antioxidant so it can help skin heal faster, rebuild itself, and repair a damaged barrier.
And on naming, even though "acid" is in the name, it's nothing like an AHA or BHA exfoliant. It's a gentle firming and soothing ingredient that supports your skin barrier.
Concentration-wise, Asiatic Acid is potent at very low doses and usually shows up as a small fraction of a broader centella extract.
Analyses of centella material put Asiatic Acid reported in the range of 0.2-3% of the extract.
This ingredient is non-sensitizing and guinea pig sensitization testing also found it to be a weak sensitizer. That means the risk of acquiring contact sensitivty is quite low.
Allergic contact dermatitis does exist but is also very rare; documented cases tend to involve prolonged use on broken skin plus co-sensitization to fragrance ingredients.
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Read more about us· Updated December 22, 2025 • Added by nabisskin