SkinBetter Science AlphaRet Overnight Cream Versus Protocol Enzyme-Active Retinol Serum
Updated on January 17, 2024
Overview
What they are
These products are both reef safe . They have a total of 8 ingredients in common
Cool Features
They both contain niacinamide, retinoid and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any common allergens, oils, parabens or sulfates
What's Inside
They both contain fragrances
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
SkinBetter Science AlphaRet Overnight Cream 52 ingredients
Protocol Enzyme-Active Retinol Serum 23 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
SkinBetter Science AlphaRet Overnight Cream 52 ingredients
Protocol Enzyme-Active Retinol Serum 23 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningSodium Glycolate
BufferingGlycolic Acid
Buffering
Cetearyl Olivate
Pentylene Glycol
Skin ConditioningCyclopentasiloxane
Emollient
Isohexadecane
EmollientSorbitan Olivate
Emulsifying
Tetrahexyldecyl Ascorbate
Antioxidant
Glycerin
Humectant
Ceresin
Emulsion StabilisingGlycol Palmitate
Emulsifying
Butylene Glycol
Humectant
Niacinamide
Smoothing
Squalane
Emollient
Methyl Gluceth-20
HumectantEthyl Lactyl Retinoate
Abrasive
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Ceramide NP
Skin Conditioning
Hyaluronic Acid
Humectant
Ubiquinone
Antioxidant
Tocopherol
Antioxidant
Bisabolol
Masking
Tocopheryl Acetate
Antioxidant
Superoxide Dismutase
Antioxidant
Butyrospermum Parkii Butter
Skin Conditioning
Allantoin Glycyrrhetinic Acid
Skin ProtectingSodium PCA
HumectantPanthenol
Skin Conditioning
Camellia Sinensis Leaf Extract
Antimicrobial
Portulaca Oleracea Extract
Skin ConditioningLinoleic Acid
Cleansing
Cholesterol
Emollient
Linolenic Acid
Cleansing
Magnesium Aluminum Silicate
AbsorbentDimethyl Isosorbide
SolventDimethicone
Emollient
Glyceryl Stearate
Emollient
PEG-100 Stearate
Steareth-2
EmulsifyingHydroxyethylcellulose
Emulsion StabilisingAcacia Senegal Gum
MaskingXanthan Gum
EmulsifyingHydrated Silica
Abrasive
Carbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
Tromethamine
BufferingDisodium EDTA
Ethylhexylglycerin
Skin ConditioningPhenoxyethanol
Preservative
CI 77891
Cosmetic ColorantWater, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, CI 77891
Aloe Barbadensis Leaf Juice
Skin Conditioning
Water
Skin ConditioningNiacinamide
Smoothing
Cyclodextrin
AbsorbentCaprylic/Capric Triglyceride
MaskingGluconolactone
Skin Conditioning
Carnitine
CleansingGlycerin
Humectant
Polysorbate 20
Emulsifying
Coenzyme A
Skin ConditioningRetinol
Skin Conditioning
Phenylethyl Resorcinol
Antioxidant
Bisabolol
Masking
Tocopheryl Acetate
Antioxidant
Lonicera Japonica Flower Extract
Skin ConditioningLonicera Caprifolium Flower Extract
Perfuming
Sodium Lactate
BufferingLecithin
EmollientAlcohol Denat.
Antimicrobial
Pentylene Glycol
Skin ConditioningMaltodextrin
AbsorbentXanthan Gum
EmulsifyingSodium Benzoate
Masking
Aloe Barbadensis Leaf Juice, Water, Niacinamide, Cyclodextrin, Caprylic/Capric Triglyceride, Gluconolactone, Carnitine, Glycerin, Polysorbate 20, Coenzyme A, Retinol, Phenylethyl Resorcinol, Bisabolol, Tocopheryl Acetate, Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Sodium Lactate, Lecithin, Alcohol Denat., Pentylene Glycol, Maltodextrin, Xanthan Gum, Sodium Benzoate
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamideBisabolol is famous for its skin soothing properties. It does this by blocking inflammatory signals, helping to reduce your body's reaction to irritation.
This ingredient also interferes with the process of hyperpigmentation. This can help with reducing dark spots and uneven tone.
Bisabolol is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. By fighting these free-radicals, Bisabolol may slow down signs of aging.
Studies have shown Bisabolol to have antimicrobial properties and may be a fungicide. These properties help preserve a product's shelf life.
All these properties makes bisabolol a great skin barrier helper ingredient.
Bisabolol also helps the absorption of other ingredients.
Note: Synthetic Bisabolol has been shown to be less effective.
Learn more about BisabololTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumPolysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
SkinBetter Science AlphaRet Overnight Cream 52 ingredients
Protocol Enzyme-Active Retinol Serum 23 ingredients
Reviews
Here's what our community thinks
SkinBetter Science AlphaRet Overnight Cream 52 ingredients
This is a great - albeit extremely expensive - alternative for people whose skin is too sensitive for tretonoin/retinols or who aren’t able to manage the dryness they can cause.
I’ve been using it for about a month and a half and I truly have noticed a huge difference in my pore size + fine lines. I do like to use a moisturizer afterwards just to be safe, but this could likely work as a Show more
Truly my holy grail product. It’s certainly pricey but it’s one of two expensive products I have in my routine and it’s worth the investment imo. One fl oz bottle lasts me ~3 months with nightly use. I’ve used this product consistently for 5 months now and have noticed my skin is brighter, more hydrated, and even toned. I was previously using .05% tret and my skin could never really handle it. Show more
