Welcome to our breakdown of the 34 best Protocol Enzyme-Active Retinol Serum dupes and alternatives.
Looking for dupes for a different product? You can use our Dupe Finder to search for them!
If you'd like to see the all of the Protocol dupes that we've found, check out our best Protocol dupes guide.
We use hundreds of science-backed factors to find you the best dupes.
Learn more about our dupe methodology
Our Roundup
Here's a quick roundup of our findings. Continue reading for the full breakdown!
Skin Script's Retinaldehyde Serum with iconicA is the dupe with the most similar ingredients. Our matching methodology puts it at an 86% ingredient match!
Of all of the dupes for this product, Maelove's Moonlight Retinal Super Serum is the most liked by our community. Our matching algorithm puts it at an 74% overall match!
- Skin Script Retinaldehyde Serum with iconicA 1
- Maelove Moonlight Retinal Super Serum 2
- Boost Lab Retinol Night Renewal Serum 3
- Face Reality Skincare Vitamin A Corrective Serum 4
- HoliFrog Moonbeam Retinol Treatment Serum 5
- Maelove Stargaze Enhanced Retinol Serum 6
- Raaie Yellow Moonbeam Retinal Elixir 7
- PCA Skin Rejuvenating Serum 8
- Eva Naturals Azelaic Acid 10% Facial Serum 9
- Rejuvaus Repair & Refine ABC Serum 10
- Boots Retinol Serum 11
- Synergy Therm Cosmetics Revive Serum 12
- Sachi Skin Ursolic Acid and Retinal Overnight Reform Serum 13
- Delia Cosmetics Niacinamide 10% + Zinc Serum 14
- Vetted Dermlab R Retinoid Serum 15
- Creamy Sérum Facial Retinal 16
- Eva Naturals Retinol Serum 17
- Mychelle Remarkable Retinal Serum 18
- Pem Delian The Pioneer 19
- Gema HerrerÃas 0,1 RETINAL-RHM 20
- Trinny London Overnight Clarity 21
- Eva Naturals 12% Niacinamide Serum for Face + 2% Zinc and Hyaluronic Acid 22
- Truly Black Jelly Blemish Treatment Body Serum 23
- By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum 24
- Boost Lab Vitamin C Brightening Serum 25
- Queen Natural New York 7-in-1 White and Bright Super Serum 26
- Vetted Dermlab Vc Vitamin C Complex Serum 27
- Tuel Hydrate Super Moisture Serum 28
- Klued 5% Niacinamide Serum 29
- Huut Refining Balance Antioxidant Serum 30
- Primark Caffeine Eye Serum 31
- Yeouth Niacinamide Serum 32
- Aspect Skincare Complete Pigment Plus 33
- Boots Niacinamide Serum 34
Overview
What it is
Serum with 23 ingredients that contains niacinamide, PHA, retinoid and Vitamin E
Cool Features
It is vegan, cruelty-free, and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any common allergens, oils, parabens, silicones or sulfates
Protocol Enzyme-Active Retinol Serum
90% match
with the ingredients and function of Skin Script Retinaldehyde Serum with iconicA
Dupe Explained
These products are both cruelty-free serums that contain niacinamide, PHA, retinoid and Vitamin E. They've got a total of 21 ingredients in common.
They both do not contain any common allergens, parabens, silicones or sulfates. They both contain harsh alcohols and fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Protocol Enzyme-Active Retinol Serum
74% match
with the ingredients and function of Maelove Moonlight Retinal Super Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide, PHA, retinoid and Vitamin E. They've got a total of 17 ingredients in common.
They both do not contain any common allergens, parabens, silicones or sulfates. They both contain harsh alcohols and fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Boost Lab Retinol Night Renewal Serum
63% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain retinoid and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Protocol Enzyme-Active Retinol Serum
61% match
with the ingredients and function of Face Reality Skincare Vitamin A Corrective Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide and retinoid. They've got a total of 10 ingredients in common.
They both do not contain any common allergens, parabens, silicones or sulfates. They both contain fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
HoliFrog Moonbeam Retinol Treatment Serum
60% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain retinoid and Vitamin E. They've got a total of 13 ingredients in common.
They both do not contain any common allergens, parabens, silicones or sulfates. They both contain fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Maelove Stargaze Enhanced Retinol Serum
60% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both vegan and cruelty-free serums that contain niacinamide, PHA and retinoid. They've got a total of 9 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates. They both contain harsh alcohols.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Raaie Yellow Moonbeam Retinal Elixir
60% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both vegan and cruelty-free serums that contain niacinamide, PHA, retinoid and Vitamin E. They've got a total of 11 ingredients in common.
They both do not contain any parabens, silicones or sulfates. They both contain fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Protocol Enzyme-Active Retinol Serum
59% match
with the ingredients and function of PCA Skin Rejuvenating Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide, PHA and Vitamin E. They've got a total of 10 ingredients in common.
They both do not contain any parabens, silicones or sulfates. They both contain harsh alcohols and fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Eva Naturals Azelaic Acid 10% Facial Serum
59% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both serums that contain niacinamide, PHA, retinoid and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Rejuvaus Repair & Refine ABC Serum
58% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide, PHA, retinoid and Vitamin E. They've got a total of 12 ingredients in common.
They both do not contain any parabens, silicones or sulfates. They both contain harsh alcohols and fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Protocol Enzyme-Active Retinol Serum
58% match
with the ingredients and function of Boots Retinol Serum
Dupe Explained
These products are both vegan and cruelty-free serums that contain retinoid and Vitamin E. They've got a total of 9 ingredients in common.
They both do not contain any common allergens, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Protocol Enzyme-Active Retinol Serum
58% match
with the ingredients and function of Synergy Therm Cosmetics Revive Serum
Dupe Explained
These products are both serums that contain niacinamide, retinoid and Vitamin E. They've got a total of 7 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, dry skin, brightening skin, sensitive skin, oily skin, reducing pores and dark spots.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Protocol Enzyme-Active Retinol Serum
58% match
with the ingredients and function of Sachi Skin Ursolic Acid and Retinal Overnight Reform Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide, retinoid and Vitamin E. They've got a total of 11 ingredients in common.
They both do not contain any common allergens, parabens, silicones or sulfates. They both contain fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Delia Cosmetics Niacinamide 10% + Zinc Serum
58% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both serums that contain niacinamide and Vitamin E. They've got a total of 9 ingredients in common.
They both do not contain any common allergens, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Vetted Dermlab R Retinoid Serum
57% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both vegan and cruelty-free serums that contain PHA and retinoid. They've got a total of 6 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Creamy Sérum Facial Retinal
57% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both vegan and cruelty-free serums that contain PHA, retinoid and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates. They both contain fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Eva Naturals Retinol Serum
57% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both serums that contain retinoid and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any common allergens, parabens, silicones or sulfates. They both contain harsh alcohols.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Mychelle Remarkable Retinal Serum
57% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain PHA, retinoid and Vitamin E. They've got a total of 10 ingredients in common.
They both do not contain any parabens, silicones or sulfates. They both contain fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Pem Delian The Pioneer
57% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both serums that contain retinoid and Vitamin E. They've got a total of 7 ingredients in common.
They both do not contain any common allergens, parabens, silicones or sulfates. They both contain fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Gema HerrerÃas 0,1 RETINAL-RHM
56% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both serums that contain retinoid and Vitamin E. They've got a total of 7 ingredients in common.
They both do not contain any oils, parabens, silicones or sulfates. They both contain harsh alcohols and fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Trinny London Overnight Clarity
56% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both serums that contain niacinamide, retinoid and Vitamin E. They've got a total of 9 ingredients in common.
They both do not contain any parabens, silicones or sulfates. They both contain harsh alcohols and fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Eva Naturals 12% Niacinamide Serum for Face + 2% Zinc and Hyaluronic Acid
56% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both serums that contain niacinamide and Vitamin E. They've got a total of 6 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Truly Black Jelly Blemish Treatment Body Serum
56% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both vegan and cruelty-free serums that contain PHA and Vitamin E. They've got a total of 6 ingredients in common.
They both do not contain any common allergens, parabens, silicones or sulfates. They both contain harsh alcohols and fragrances.
They're both likely to be good for anti aging, dry skin, brightening skin, oily skin, scar healing and better texture.
Both products are also reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum
55% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide and Vitamin E. They've got a total of 7 ingredients in common.
They both do not contain any parabens, silicones or sulfates. They both contain fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Boost Lab Vitamin C Brightening Serum
54% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide and Vitamin E. They've got a total of 6 ingredients in common.
They both do not contain any common allergens, parabens or silicones.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Queen Natural New York 7-in-1 White and Bright Super Serum
54% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both serums that contain niacinamide and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any common allergens, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Vetted Dermlab Vc Vitamin C Complex Serum
54% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both vegan and cruelty-free serums that contain niacinamide and PHA. They've got a total of 6 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Tuel Hydrate Super Moisture Serum
53% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide and PHA. They've got a total of 6 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Klued 5% Niacinamide Serum
53% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide and Vitamin E. They've got a total of 6 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores and dark spots.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Huut Refining Balance Antioxidant Serum
53% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide, retinoid and Vitamin E. They've got a total of 5 ingredients in common.
They both do not contain any common allergens, oils, parabens or silicones. They both contain fragrances.
They're both likely to be good for fighting acne, anti aging, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Primark Caffeine Eye Serum
53% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide and Vitamin E. They've got a total of 7 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, dry skin, brightening skin, oily skin, reducing pores and dark spots.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Yeouth Niacinamide Serum
52% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide and Vitamin E. They've got a total of 6 ingredients in common.
They both do not contain any common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores and dark spots.
Both products are also reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Aspect Skincare Complete Pigment Plus
52% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both cruelty-free serums that contain niacinamide and Vitamin E. They've got a total of 7 ingredients in common.
They both do not contain any parabens, silicones or sulfates. They both contain fragrances.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Boots Niacinamide Serum
51% match
with the ingredients and function of Protocol Enzyme-Active Retinol Serum
Dupe Explained
These products are both vegan and cruelty-free serums that contain niacinamide. They've got a total of 8 ingredients in common.
They both do not contain any common allergens, parabens or sulfates.
They're both likely to be good for fighting acne, dry skin, brightening skin, sensitive skin, oily skin, reducing pores and dark spots.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
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