What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Skin ConditioningPentylene Glycol
Skin Conditioning
Hamamelis Virginiana Extract
Antiseborrhoeic
Glycerin
Humectant
Dimethyl Sulfone
SolventHuman Umbilical Mesenchymal Stem Cell Exosomes
Alpha-Arbutin
Antioxidant
Palmitoyl Tripeptide-5
Skin Conditioning
Ergothioneine
Antioxidant
Dipalmitoyl Hydroxyproline
Skin Conditioning
Ubiquinone
Antioxidant
Saccharomyces Ferment Lysate Filtrate
Skin Conditioning
Tetrahexyldecyl Ascorbate
Antioxidant
Sh-Oligopeptide-1
Skin Conditioning
Rh-Polypeptide-3
Skin Conditioning
Sh-Polypeptide-9
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-11
Human Urine Derived Stem Cell Conditioned Media
EmollientGlycereth-7 Triacetate
EmollientEthoxydiglycol
HumectantLactococcus Ferment Lysate
Skin Conditioning
Chlorella Vulgaris Extract
Skin ConditioningSaccharide Isomerate
Humectant
Tripeptide-2
Skin Conditioning
Dimer Tripeptide-43
Vitis Vinifera Flower Cell Extract
MaskingPyrus Malus Fruit Extract
Skin Conditioning
Hydroxyacetophenone
Antioxidant
Tocopheryl Acetate
Antioxidant
Propanediol
Solvent
Xanthan Gum
EmulsifyingLecithin
Emollient
Pullulan
Butylene Glycol
Humectant
Sodium Citrate
BufferingPolysorbate 20
Emulsifying
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Skin ConditioningPalmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Acetyl Hexapeptide-51 Amide
Skin Conditioning
Nannochloropsis Oculata Extract
HumectantCentella Asiatica Extract
Cleansing
Chondrus Crispus Extract
Skin Conditioning
Equisetum Arvense Extract
AstringentGeranium Maculatum Extract
TonicTaraxacum Officinale Root Extract
Skin ConditioningAchillea Millefolium Flower Extract
Antioxidant
Curcuma Longa Rhizome Extract
Skin ConditioningSpirulina Platensis Extract
Skin ProtectingAloe Barbadensis Leaf Juice
Skin Conditioning
Cassia Angustifolia Seed Polysaccharide
Skin ConditioningSimmondsia Chinensis Seed Oil
Emollient
Arginine
Masking
Aspartic Acid
Masking
Glycine
Buffering
Alanine
Masking
Serine
Masking
Valine
MaskingIsoleucine
Skin ConditioningProline
Skin Conditioning
Threonine
Histidine
Humectant
Phenylalanine
Masking
PCA
Humectant
Sodium PCA
Humectant
Sodium Lactate
Buffering
Sodium Chloride
MaskingCarbomer
Emulsion StabilisingAlcohol
Antimicrobial
Hydroxyethylcellulose
Emulsion StabilisingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingSodium Hydroxide
BufferingPotassium Sorbate
Preservative
Sodium Benzoate
Masking
Dextran
Disodium EDTA
Phenoxyethanol
Preservative
Ethylhexylglycerin
Skin ConditioningWater, Pentylene Glycol, Hamamelis Virginiana Extract, Glycerin, Dimethyl Sulfone, Human Umbilical Mesenchymal Stem Cell Exosomes, Alpha-Arbutin, Palmitoyl Tripeptide-5, Ergothioneine, Dipalmitoyl Hydroxyproline, Ubiquinone, Saccharomyces Ferment Lysate Filtrate, Tetrahexyldecyl Ascorbate, Sh-Oligopeptide-1, Rh-Polypeptide-3, Sh-Polypeptide-9, Sh-Polypeptide-1, Sh-Polypeptide-11, Human Urine Derived Stem Cell Conditioned Media, Glycereth-7 Triacetate, Ethoxydiglycol, Lactococcus Ferment Lysate, Chlorella Vulgaris Extract, Saccharide Isomerate, Tripeptide-2, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Hexapeptide-51 Amide, Nannochloropsis Oculata Extract, Centella Asiatica Extract, Chondrus Crispus Extract, Equisetum Arvense Extract, Geranium Maculatum Extract, Taraxacum Officinale Root Extract, Achillea Millefolium Flower Extract, Curcuma Longa Rhizome Extract, Spirulina Platensis Extract, Aloe Barbadensis Leaf Juice, Cassia Angustifolia Seed Polysaccharide, Simmondsia Chinensis Seed Oil, Arginine, Aspartic Acid, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, PCA, Sodium PCA, Sodium Lactate, Sodium Chloride, Carbomer, Alcohol, Hydroxyethylcellulose, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Potassium Sorbate, Sodium Benzoate, Dextran, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin
Hyaluronic Acid
Humectant
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Teprenone
Skin ConditioningSodium Carboxymethyl Beta-Glucan
CleansingSuperoxide Dismutase
Antioxidant
Sodium PCA
Humectant
Pseudoalteromonas Ferment Extract
Humectant
Resveratrol
Antioxidant
Trehalose
Humectant
Triacetin
AntimicrobialSodium Hyaluronate
Humectant
Oryza Sativa Bran Water
Masking
Palmitoyl Tripeptide-5
Skin Conditioning
Glycerin
Humectant
Phospholipids
Skin Conditioning
Argania Spinosa Sprout Cell Extract
Skin ConditioningRhododendron Ferrugineum Extract
MaskingSaccharomyces Cerevisiae Extract
Skin Conditioning
Urea
Buffering
Laminaria Cloustoni Extract
Skin ProtectingDipalmitoyl Hydroxyproline
Skin Conditioning
Lecithin
Emollient
Linoleic Acid
Cleansing
Mannitol
Humectant
Sodium Ascorbate
Antioxidant
Tall Oil Sterol
Emollient
Tocopherol
Antioxidant
Dipotassium Glycyrrhizate
Humectant
Vitis Vinifera Seed Extract
Antimicrobial
Allantoin
Skin Conditioning
Panthenol
Skin Conditioning
Aloe Barbadensis Leaf Juice
Skin Conditioning
Squalane
Emollient
Glucose
Humectant
Glucose Oxidase
StabilisingLactoperoxidase
StabilisingHyaluronic Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Teprenone, Sodium Carboxymethyl Beta-Glucan, Superoxide Dismutase, Sodium PCA, Pseudoalteromonas Ferment Extract, Resveratrol, Trehalose, Triacetin, Sodium Hyaluronate, Oryza Sativa Bran Water, Palmitoyl Tripeptide-5, Glycerin, Phospholipids, Argania Spinosa Sprout Cell Extract, Rhododendron Ferrugineum Extract, Saccharomyces Cerevisiae Extract, Urea, Laminaria Cloustoni Extract, Dipalmitoyl Hydroxyproline, Lecithin, Linoleic Acid, Mannitol, Sodium Ascorbate, Tall Oil Sterol, Tocopherol, Dipotassium Glycyrrhizate, Vitis Vinifera Seed Extract, Allantoin, Panthenol, Aloe Barbadensis Leaf Juice, Squalane, Glucose, Glucose Oxidase, Lactoperoxidase
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.
Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.
Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.
It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.
Learn more about Aloe Barbadensis Leaf JuiceDipalmitoyl Hydroxyproline isn't fungal acne safe.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Learn more about LecithinPalmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".
"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.
This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.
Clinical testing showed statistically significant improvements in:
Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.
You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Palmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier.
This peptide has a "build more, lose less" approach.
It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein.
The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days.
This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers.
Typical use levels range from 1-3% and this ingredient gets along with pretty much everything.
On the fungal acne front:
Although palmitic acid sits in the chain length that Malassezia can feed on, this ingredient has it locked in an amine bond. This makes it hard for Malassezia to access as a source of food, and therefore fungal acne safe.
Sodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.
The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.
This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.
Learn more about Sodium PCA
