Versus

Neutrogena Healthy Defense Daily Face Moisturizer -SPF 50 Versus ZO Skin Health Smart Tone Broad-Spectrum SPF 50

General Moisturizer
Sunscreen
American Brand United States
American Brand United States

Updated on July 27, 2023

Overview

Cool Features

They both contain retinoid, SPF, Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any sulfates

What's Inside

They both contain fragrances and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Healthy Defense Daily Face Moisturizer -SPF 50
Smart Tone Broad-Spectrum SPF 50

Butyl Methoxydibenzoylmethane 3%

UV Absorber
Chemical UV Filter IconMay cause irritation IconMay worsen Rosacea Icon

Homosalate 10%

Skin Conditioning
Chemical UV Filter IconNon-Reef-Safe Icon

Ethylhexyl Salicylate 5%

UV Absorber
0 / 0 Chemical UV Filter IconNon-Reef-Safe IconMay worsen Rosacea Icon

Octocrylene 10%

UV Absorber
Chemical UV Filter IconNon-Reef-Safe IconMay worsen Eczema Icon

Water

Skin Conditioning

Dimethicone

Emollient
1 / 0 Silicon Icon

Butyloctyl Salicylate

Skin Conditioning
Non-Reef-Safe Icon

Styrene/Acrylates Copolymer

Dimethicone/Divinyldimethicone/Silsesquioxane Crosspolymer

Humectant

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Mica

Cosmetic Colorant
May worsen Eczema Icon

PEG-100 Stearate

0 / 0 Not safe for Fungal Acne Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Polyamide-5

Skin Conditioning

Steareth-21

Cleansing

Argania Spinosa Kernel Oil

Emollient
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Petasites Japonicus Root Extract

Skin Conditioning

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Retinyl Palmitate

Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Caprylyl Glycol

Emollient

Hexylene Glycol

Emulsifying
0-2 / 0-1

Melanin

Skin Protecting

Pentylene Glycol

Skin Conditioning

Boron Nitride

Absorbent

Ethyl Ferulate

Antioxidant
Antioxidant Icon

C12-15 Alkyl Benzoate

Antimicrobial

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Ethylene Brassylate

Masking

Polymethyl Methacrylate

Acrylates/Ammonium Methacrylate Copolymer

Dimethicone/Vinyl Dimethicone Crosspolymer

Skin Conditioning

Disodium EDTA

Acrylates Crosspolymer-4

Emulsion Stabilising

Panthenyl Triacetate

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Aluminum Hydroxide

Emollient

Simethicone

Emollient
1 / 0 Silicon Icon

Ethyl Linoleate

Emollient
Fragrance IconNot safe for Fungal Acne Icon

Oleyl Alcohol

Emollient
4 / 2 Fatty Alcohol IconFragrance IconBad for Acne Prone Skin Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

PEG-8 Laurate

Emulsifying
Not safe for Fungal Acne Icon

Steareth-2

Emulsifying
2 / 2

Coco-Glucoside

Cleansing

Isostearic Acid

Cleansing
Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Sodium Hydroxide

Buffering

Phenoxyethanol

Preservative
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

Ethylhexylglycerin

Skin Conditioning

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Titanium Dioxide

Cosmetic Colorant
0 / 0 Mineral UV Filter IconNon-Reef-Safe Icon

Iron Oxides

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

UV Absorber, UV Filter

Also known as Avobenzone, this ingredient is a chemical sunscreen filter that provides protection in the UV-A range.

Avobenzone is globally approved and is the most commonly used UV-A filter in the world.

Studies have found that avobenzone becomes ineffective when exposed to UV light (it is not photostable; meaning that it breaks down in sunlight). Because of this, formulations that include avobenzone will usually contain stabilizers such as octocrylene.

However, some modern formulations (looking at you, EU!) are able to stabilize avobenzone by coating the molecules.

Avobenzone does not protect against the UV-B range, so it's important to check that the sunscreen you're using contains other UV filters that do!

The highest concentration of avobenzone permitted is 3% in the US, and 5% in the EU.

Learn more about Butyl Methoxydibenzoylmethane
Skin Conditioning, UV Absorber, UV Filter

Homosalate is a chemical sunscreen filter that provides protection in the UV-B range (280nm - 320 nm), with a peak protection at 306 nm. It is internationally approved for use in sunscreens.

Homosalate is not photo-stable, meaning it's strength as a UV filter degrades over time with exposure to the sun. Because of this, it's often used in combination with other chemical sunscreen filters as avobenzone (which protects from the UV-A range). Homosalate also helps act as a solvent for harder-to-dissolve UV filters.

(Part of the reason that sunscreens need to be frequently re-applied is due to the photo instability of many chemical sunscreen filters)

Currently, homosalate is approved in concentrations up to 10% in the EU and 15% in the US. The FDA is currently doing further research on the effects of homosalate, and it is possible that these approved concentrations will change in the future.

Learn more about Homosalate
UV Absorber, UV Filter

Ethylhexyl Salicylate is an organic compound used to block UV rays. It primarily absorbs UVB rays but offers a small amount of UVA protection as well.

Commonly found in sunscreens, Ethylhexyl Salicylate is created from salicylic acid and 2-ethylhexanol. You might know salicylic acid as the effective acne fighter ingredient and BHA.

The ethylhexanol in this ingredient is a fatty alcohol and helps hydrate your skin, similar to oils. It is an emollient, which means it traps moisture into the skin.

According to manufacturers, Ethylhexyl Salicylate absorbs UV wavelength of 295-315 nm, with a peak absorption at 307-310 nm. UVA rays are linked to long term skin damage, such as hyperpigmentation. UVB rays emit more energy and are capable of damaging our DNA. UVB rays cause sunburn.

Learn more about Ethylhexyl Salicylate
UV Absorber, UV Filter

Octocrylene protects skin from sun damage. It absorbs UV-B with peak absorption of 304 nm. It is a common sunscreen ingredient and often paired with avobenzone, a UVA filter. This is because octocrylene stabilizes other sunscreen ingredients by protecting them from degradation when exposed to sunlight. Octocrylene is a photostable ingredient and loses about 10% of SPF in 95 minutes.

Octocrylene also acts as an emollient, meaning it helps skin retain moisture and softens skin. It is oil-soluble and hydrophobic, enhancing water-resistant properties in a product.

Those who are using ketoprofen, a topical anti-inflammatory drug, may experience an allergic reaction when using octocrylene. It is best to speak with a healthcare professional about using sunscreens with octocrylene.

The EU allows a maximum of these concentrations:

Learn more about Octocrylene
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Emulsifying

Glyceryl Stearate is a mix of glycerin and stearic acid.

It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.

As an emollient, it helps soften skin and supports barrier-replenishing ingredients.

In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.

This ingredient may not be fungal-acne safe

Fun fact: The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate

Peg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.

PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

Emollient, Emulsifying, Emulsion Stabilising

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.

Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.

Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.

Learn more about Cetearyl Alcohol
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Skin Conditioning

Retinyl palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include tretinoin and retinol.

This particular ingredient has had a bumpy year with its rise and fall in popularity.

First, Retinyl palmitate is created from palmitic acid and retinol. It is a retinol ester and considered one of the weaker forms of retinoid.

This is because all retinoids have to be converted to Tretinoin, AKA retinoic acid. Retinyl Palmitate is pretty far down the line and has to go through multiple conversions before its effects are seen.

Due to this long and ineffective conversion line, the benefits of Retinyl Palmitate are debated.

Studies show Retinyl Palmitate to help:

Dermatologists say this ingredient is ineffective because it isn't used in high enough concentrations in cosmetics.

This ingredient used to be found in sunscreens to boost the efficacy of sunscreen filters.

The downfall of Retinyl Palmitate was due to released reports about the ingredient being correlated to sun damage and skin tumors.

While there is a study showing this ingredient to cause DNA damage when exposed to UV-A, there is no concrete proof of it being linked to skin cancer. It is safe to use when used correctly.

All retinoids increase your skin's sensitivity to the sun in the first few months of usage. Be especially careful with reapplying sunscreen when using any form of retinoid.

Currently, this ingredient is still allowed in cosmetics all over the world. In Canada, cosmetics must have a warning label stating the product to contain Retinyl Palmitate

Fun fact: This ingredient is often added to low-fat milk to increase the levels of Vitamin A.

Learn more about Retinyl Palmitate
Antioxidant, Buffering, Masking

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Not only is vitamin C great for your overall health and immune system, it also has plenty of benefits on your skin.

Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.

Remember: Vitamin C should not replace sunscreen!

Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.

Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.

The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.

Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Learn more about Ascorbic Acid
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol

We don't have a description for Polymethyl Methacrylate yet.

We don't have a description for Styrene/Acrylates Copolymer yet.

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA

When to use

5 Routines
100% use in am
0% use in pm
100% use every day
5 Routines
100% use in am
0% use in pm
100% use every day