Versus

ma:nyo 4GF Ampoule Eye Cream Versus ma:nyo Bifida Biome Concentrate Eye Cream

Ampoule
Eye Moisturizer
Korean Brand South Korea
Korean Brand South Korea

Updated on May 15, 2024

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 15 ingredients in common

Cool Features

They both contain hyaluronic acid, niacinamide and peptides

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
4GF Ampoule Eye Cream

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Hydrolyzed Collagen Extract

Skin Protecting
Helps with Anti-Aging Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Polyglyceryl-6 Stearate

Emollient
Not safe for Fungal Acne Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Isoamyl Laurate

Emollient
Not safe for Fungal Acne Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Sh-Oligopeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging IconGood for Scar Healing Icon

Polypeptide-1

Skin Conditioning
Peptide Icon

Oligopeptide-2

Skin Conditioning
Peptide Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Scar Healing Icon

Betaine

Humectant
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots Icon

Trehalose

Humectant
Helps hydrate Dry Skin Icon

Hydrolyzed Wheat Protein

Skin Conditioning

Padina Pavonica Extract

Skin Conditioning

Rosa Hybrid Flower

Skin Conditioning

Lactobacillus

Skin Conditioning

Chenopodium Quinoa Extract

Skin Conditioning

Citrus Aurantium Amara Flower Oil

Masking
Oil Icon

Morus Alba Bark Extract

Skin Conditioning

Water

Skin Conditioning

Pyrus Malus Fruit Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Hydrolyzed Carrot Extract

Skin Conditioning

Pumice Extract

Antioxidant
Antioxidant Icon

Michelia Alba Flower Extract

Skin Conditioning

Malpighia Emarginata Fruit Extract

Skin Conditioning

Glycyrrhiza Glabra Root Extract

Bleaching
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Daucus Carota Sativa Root Extract

Skin Conditioning
Helps reduce irritation Icon

Potassium Olivoyl Hydrolyzed Oat Protein

Cleansing

Gold

Cosmetic Colorant

Illicium Verum Fruit Extract

Perfuming
Fragrance Icon

Caprylyl Glycol

Emollient

Polyglyceryl-2 Stearate

Emulsifying
Not safe for Fungal Acne Icon

Ethylhexylglycerin

Skin Conditioning

Propanediol Dicaprylate

Emollient

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Polyglyceryl-6 Behenate

Emulsion Stabilising
Not safe for Fungal Acne Icon

Stearyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Glyceryl Caprylate

Emollient

Sorbitol

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Glyceryl Oleate

Emollient
Fragrance IconNot safe for Fungal Acne Icon

Coriandrum Sativum Extract

Skin Conditioning

Snail Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Gorgonia Extract

Skin Conditioning

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Sodium Dna

Skin Conditioning
Helps with Anti-Aging IconGood for Dark Spots Icon

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconGood for Scar Healing IconNot safe for Fungal Acne Icon

Oenothera Biennis Oil

Emollient
3 / 2 Oil IconHelps reduce irritation IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Olea Europaea Fruit Oil

Masking
0-2 / 0 Fragrance IconOil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Sesamum Indicum Seed Oil

Emollient
1-3 / 0 Oil IconNot safe for Fungal Acne Icon

Hydrogenated Olive Oil

Skin Conditioning
Oil IconNot safe for Fungal Acne Icon

Rosa Damascena Flower Oil

Masking
Oil Icon

Rose Flower Oil

Masking
Oil IconMay cause irritation IconEU Allergen Icon

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Cinnamyl Alcohol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Citronellol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Geraniol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon
Bifida Biome Concentrate Eye Cream

Bifida Ferment Lysate 43%

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Lactobacillus/Pumpkin Fruit Ferment Filtrate 20%

Skin Conditioning

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Dipropylene Glycol

Masking

Caprylyl Methicone

Skin Conditioning
Silicon Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Diisostearyl Malate

Emollient

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Cutibacterium Granulosum Ferment Extract Filtrate

Emollient

Centella Asiatica Leaf Water

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Lupinus Albus Seed Extract

Skin Conditioning

Persea Gratissima Fruit Extract

Emollient

Fucus Vesiculosus Extract

Emollient
Helps hydrate Dry Skin Icon

Prunella Vulgaris Extract

Antioxidant
Antioxidant Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Glucose

Humectant
Helps hydrate Dry Skin Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Hydroxypropyltrimonium Hyaluronate

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Scar Healing Icon

Potassium Hyaluronate

Skin Conditioning

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Ethylhexylglycerin

Skin Conditioning

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Cetearyl Glucoside

Emulsifying

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Copper Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Scar Healing Icon

Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Pentapeptide-4

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Hexapeptide-11

Skin Conditioning
Peptide Icon

Hexapeptide-9

Skin Conditioning
Peptide Icon

Nonapeptide-1

Skin Conditioning
Peptide Icon

Palmitic Acid

Emollient
2 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Dipentaerythrityl Hexa C5-9 Acid Esters

Skin Conditioning

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Sorbitan Isostearate

Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon

Caprylyl Glycol

Emollient

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

C12-16 Alcohols

Emollient

Tromethamine

Buffering

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Maltodextrin

Absorbent
Helps hydrate Dry Skin Icon

Alanine/Histidine/Lysine Polypeptide Copper Hcl

Skin Conditioning
Peptide Icon

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Having a healthy microbiome helps protect our skin against infection. It also helps our skin stay hydrated and healthy.

Studies also show this ingredient to be a promising soothing ingredient for sensitive skin.

Learn more about Bifida Ferment Lysate
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Emulsifying, Emulsion Stabilising

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.

Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.

Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.

Learn more about Cetearyl Alcohol
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Is squalane an oil?

Squalane is often called an oil, but it’s technically not; it’s a hydrocarbon, meaning it’s only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.

The term “oil-free” isn’t regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. It’s worth testing out simple oils or squalane to see what works best for your skin.

Learn more about Squalane
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Humectant, Skin Conditioning

Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.

Argireline has a similar function to botox; it prevents muscle movement and contractions slightly. By preventing muscles from moving, argireline also prohibits the formation of fine lines and wrinkles. However, research is lacking in proving this ingredient to be as effective as botox.

On the other hand, argireline tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Read more about other common types of peptides here:

Learn more about Acetyl Hexapeptide-8
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine

When to use

8 Routines
50% use in am
50% use in pm
88% use every day
8 Routines
50% use in am
50% use in pm
100% use every day

Reviews

Here's what our community thinks

ma:nyo 4GF Ampoule Eye Cream 65 ingredients

4GF Ampoule Eye Cream hasn't been rated yet.
Rate it now

ma:nyo Bifida Biome Concentrate Eye Cream 54 ingredients

5.0 /5
from 1 rating
Absorbs Well (1) Hydrating (1) No Scent (1)
ClaireEstelle's avatar

Claire L.

11 months ago
Review

Contains a lot of peptides. Doesn't irritate my eyes or make them sting. The tube is 1 oz. so it's a great value (most eye creams come in 0.5 oz. amounts). I do feel like my crows feet are less pronounced since I started using this regularly.

#hydrating
#absorbs well
#no scent
#works well