Lancôme Rénergie H.P.N. 300-Peptide Cream SPF 25 Versus Lancôme Genifique Advanced Youth Activating Eye Cream
This anti-aging day moisturizer is formulated around Adenosine to soften the look of wrinkles.
This anti-aging eye moisturizer is formulated around Bifida Ferment Lysate and Ascorbyl Glucoside to soften the look of wrinkles and strengthen the skin barrier.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Butyl Methoxydibenzoylmethane 3%
UV AbsorberEthylhexyl Salicylate 5%
UV AbsorberOctocrylene 7%
UV AbsorberWater
Skin ConditioningGlycerin
HumectantSilica
AbrasiveDimethicone
EmollientIsononyl Isononanoate
EmollientPropanediol
SolventBis-PEG-18 Methyl Ether Dimethyl Silane
EmollientPolyglyceryl-6 Distearate
EmulsifyingJojoba Esters
EmollientTocopherol
AntioxidantLimnanthes Alba Seed Oil
Skin ConditioningCyclodextrin
AbsorbentHydrolyzed Lupine Protein
Skin ConditioningPisum Sativum Extract
Skin ConditioningAdenosine
Skin ConditioningCapryloyl Salicylic Acid
ExfoliatingCitric Acid
BufferingDisodium EDTA
ChelatingHydrolyzed Linseed Extract
Skin ConditioningHydroxyacetophenone
AntioxidantScutellaria Baicalensis Root Extract
AstringentSodium Hyaluronate
HumectantSodium Hydroxide
BufferingTitanium Dioxide
Cosmetic ColorantAcacia Decurrens Flower Wax
EmollientAmmonium Acryloyldimethyltaurate/Steareth-25 Methacrylate Crosspolymer
Emulsion StabilisingCaprylyl Glycol
EmollientCetyl Alcohol
EmollientDisodium Stearoyl Glutamate
CleansingHelianthus Annuus Seed Wax
Skin ConditioningPolyglycerin-3
HumectantPolyglyceryl-3 Beeswax
EmulsifyingXanthan Gum
EmulsifyingDimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningDimethiconol
EmollientBenzyl Alcohol
PerfumingGeraniol
PerfumingLimonene
PerfumingCI 17200
Cosmetic ColorantPhenoxyethanol
PreservativeSodium Benzoate
MaskingParfum
MaskingButyl Methoxydibenzoylmethane 3%, Ethylhexyl Salicylate 5%, Octocrylene 7%, Water, Glycerin, Silica, Dimethicone, Isononyl Isononanoate, Propanediol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Polyglyceryl-6 Distearate, Jojoba Esters, Tocopherol, Limnanthes Alba Seed Oil, Cyclodextrin, Hydrolyzed Lupine Protein, Pisum Sativum Extract, Adenosine, Capryloyl Salicylic Acid, Citric Acid, Disodium EDTA, Hydrolyzed Linseed Extract, Hydroxyacetophenone, Scutellaria Baicalensis Root Extract, Sodium Hyaluronate, Sodium Hydroxide, Titanium Dioxide, Acacia Decurrens Flower Wax, Ammonium Acryloyldimethyltaurate/Steareth-25 Methacrylate Crosspolymer, Caprylyl Glycol, Cetyl Alcohol, Disodium Stearoyl Glutamate, Helianthus Annuus Seed Wax, Polyglycerin-3, Polyglyceryl-3 Beeswax, Xanthan Gum, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethiconol, Benzyl Alcohol, Geraniol, Limonene, CI 17200, Phenoxyethanol, Sodium Benzoate, Parfum
Water
Skin ConditioningCyclohexasiloxane
EmollientBifida Ferment Lysate
Skin ConditioningGlycerin
HumectantPropanediol
SolventAlcohol Denat.
AntimicrobialPolysilicone-11
Dimethicone
EmollientPolymethylsilsesquioxane
Di-C12-13 Alkyl Malate
EmollientAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingCI 77891
Cosmetic ColorantAscorbyl Glucoside
AntioxidantMica
Cosmetic ColorantLactobacillus Ferment
Skin ConditioningHydrogenated Vegetable Oil
EmollientSodium Hyaluronate
HumectantSodium Benzoate
MaskingHydrolyzed Wheat Protein
Skin ConditioningSodium
Sodium Dehydroacetate
PreservativeSodium Succinate
BufferingPhenoxyethanol
PreservativeAdenosine
Skin ConditioningYeast Extract
Skin ConditioningPtfe
PEG-10 Dimethicone
Skin ConditioningArginine
MaskingTriethanolamine
BufferingChlorphenesin
AntimicrobialChlorhexidine Digluconate
AntimicrobialPolygonum Fagopyrum Seed Extract
Skin ConditioningSilica
AbrasiveSalicyloyl Phytosphingosine
Skin ConditioningChlorella Vulgaris Extract
Skin ConditioningDimethiconol
EmollientLimonene
PerfumingPentylene Glycol
Skin ConditioningSynthetic Fluorphlogopite
Linalool
PerfumingPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantBiosaccharide Gum-1
HumectantCaprylic/Capric Triglyceride
MaskingCarbomer
Emulsion StabilisingBoron Nitride
AbsorbentAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingGeraniol
PerfumingBis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone
EmollientDisodium EDTA
ChelatingCeteareth-20
CleansingPotassium Cetyl Phosphate
EmulsifyingCitronellol
PerfumingMethionine
Skin ConditioningPotassium Sorbate
PreservativeGlycine
BufferingParfum
MaskingWater, Cyclohexasiloxane, Bifida Ferment Lysate, Glycerin, Propanediol, Alcohol Denat., Polysilicone-11, Dimethicone, Polymethylsilsesquioxane, Di-C12-13 Alkyl Malate, Ammonium Polyacryloyldimethyl Taurate, CI 77891, Ascorbyl Glucoside, Mica, Lactobacillus Ferment, Hydrogenated Vegetable Oil, Sodium Hyaluronate, Sodium Benzoate, Hydrolyzed Wheat Protein, Sodium, Sodium Dehydroacetate, Sodium Succinate, Phenoxyethanol, Adenosine, Yeast Extract, Ptfe, PEG-10 Dimethicone, Arginine, Triethanolamine, Chlorphenesin, Chlorhexidine Digluconate, Polygonum Fagopyrum Seed Extract, Silica, Salicyloyl Phytosphingosine, Chlorella Vulgaris Extract, Dimethiconol, Limonene, Pentylene Glycol, Synthetic Fluorphlogopite, Linalool, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Biosaccharide Gum-1, Caprylic/Capric Triglyceride, Carbomer, Boron Nitride, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Geraniol, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Disodium EDTA, Ceteareth-20, Potassium Cetyl Phosphate, Citronellol, Methionine, Potassium Sorbate, Glycine, Parfum
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeDimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAGeraniol is used to add fragrance/parfum to a product. It is the main component of citronellol. It is a monoterpenoid and an alcohol.
Monoterpenes are naturally found in many parts of different plants.
Geraniol can be found in many essential oils including Rose Oil and Citronella Oil. The scent of Geraniol is often described as "rose-like". Many foods also contain Geraniol for fruit flavoring.
Geraniol can irritate the skin when exposed to air. However, irritation depends on the ability of geraniol to penetrate into the skin. In general, geraniol is not able to penetrate skin easily.
Geraniol is colorless and has low water-solubility. However, it is soluble in common organic solvents.
Like citronellol, it is a natural insect repellent.
2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-
Learn more about GeraniolGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLimonene is the compound that gives citrus peel its smell.
In skincare, it shows up as a standalone fragrance ingredient or as a natural compound of citrus and other essential oils.
You'll typically see this ingredient used in very small amounts; anything above 0.001% in a leave-on product or 0.01% in a rinse-off has to be named on the label in the EU. The citrus oils that carry it sit around 0.5-1% in a finished formula.
Fresh limonene is a weak allergen; the real issue is that it slowly reacts with air and then breaks down from oxidation to create hydroperoxides (which are strong sensitizers). This is why suppliers are required to keep the peroxide value below 20 mmol.
Positive reactions in people being investigated for eczema vary:
It's worth skipping if you have a known fragrance allergy or a compromised barrier, but the risk is low for most people.
Older or long-opened products are also more likely to bother you than fresh ones due to oxidation.
Learn more about LimoneneParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolSilica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
Though it has exfoliant properties, the function of silica varies depending on the product.
The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.
It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.
Learn more about SilicaSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water