Versus

La Roche-Posay Toleriane Ultra Night Moisturizer Versus MediCube Triple Collagen Cream

Night Moisturizer
General Moisturizer
French Brand
Korean Brand

Updated on June 19, 2024

Overview

What they are

These products are both reef safe . They have a total of 10 ingredients in common

Cool Features

They both contain niacinamide and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Triple Collagen Cream

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Dipropylene Glycol

Masking

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Cyclopentasiloxane

Emollient
Silicon Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Triethylhexanoin

Masking

Hydrogenated Polydecene

Emollient

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Hydrogenated Poly(C6-14 Olefin)

Emollient

Cyclohexasiloxane

Emollient
Silicon Icon

Glyceryl Stearate Se

Emulsifying
3 / 2 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Dioscorea Japonica Root Extract

Skin Conditioning

Aesculus Hippocastanum Extract

Antioxidant
Antioxidant Icon

Laminaria Japonica Extract

Skin Protecting
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Eclipta Prostrata Leaf Extract

Skin Conditioning

Collagen Extract

Skin Conditioning
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Argania Spinosa Kernel Oil

Emollient
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconNot safe for Fungal Acne Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Cetearyl Olivate

Not safe for Fungal Acne Icon

C12-16 Alcohols

Emollient

Dimethicone

Emollient
1 / 0 Silicon Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

PEG-100 Stearate

0 / 0 Not safe for Fungal Acne Icon

Microcrystalline Cellulose

Absorbent

Cetearyl Glucoside

Emulsifying

Sorbitan Olivate

Emulsifying
Not safe for Fungal Acne Icon

Fructose

Humectant
Helps hydrate Dry Skin Icon

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Palmitic Acid

Emollient
2 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Betaine

Humectant
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots Icon

Cellulose Gum

Emulsion Stabilising
0 / 0

Hydrolyzed Corn Starch

Humectant

Polysorbate 60

Emulsifying
Not safe for Fungal Acne Icon

Ethylhexylglycerin

Skin Conditioning

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Hydrogenated Polyisobutene

Emollient
1 / 2

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Scar Healing Icon

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Disodium EDTA

Isononyl Isononanoate

Emollient

Polyglyceryl-10 Stearate

Skin Conditioning
Not safe for Fungal Acne Icon

Sorbitan Isostearate

Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon

Sucrose

Humectant
Helps hydrate Dry Skin Icon

Stearic Acid

Cleansing
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Polyglyceryl-2 Dipolyhydroxystearate

Skin Conditioning
Not safe for Fungal Acne Icon

Fructooligosaccharides

Humectant
Helps hydrate Dry Skin Icon

Inulin Lauryl Carbamate

Emulsion Stabilising

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Disodium Stearoyl Glutamate

Cleansing

Collagen

Moisturising
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Hydrolyzed Elastin

Emollient

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Potassium Sorbate

Preservative
Preservative Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Benzyl Salicylate

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Limonene

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Hydroxycitronellal

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Skin Conditioning

Butyrospermum Parkii Butter is a plant lipid from the fruit of the Shea Tree. It is an effective skin hydrator and emollient.

Emollients help soothe and soften your skin. It does this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.

Shea butter is rich in antioxidants. Antioxidants help fight free-radicals, or molecules that may harm the body. It is also full of fatty acids including stearic acid and linoleic acid. These acids help replenish the skin and keep skin moisturized.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

Shea butter may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Learn more about Butyrospermum Parkii Butter
Masking, Buffering

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.

If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.

Read more about some other popular AHA's here:

Learn more about Citric Acid
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Is squalane an oil?

Squalane is often called an oil, but it’s technically not; it’s a hydrocarbon, meaning it’s only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.

The term “oil-free” isn’t regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. It’s worth testing out simple oils or squalane to see what works best for your skin.

Learn more about Squalane
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

88 Routines
10% use in am
90% use in pm
95% use every day
When to use See routines that use it ->
54 Routines
41% use in am
59% use in pm
93% use every day
When to use See routines that use it ->

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Broke Me Out 67% Irritating 67% Oily 67%
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