Versus

CeraVe Resurfacing Retinol Serum - USA Versus Oxecure Acne Defense Prebio Serum

Serum
Serum
American Brand United States
Thai Brand Thailand

Updated on May 19, 2025

Overview

What they are

These products are both reef safe serums. They have a total of 13 ingredients in common

Cool Features

They both contain ceramides and hyaluronic acid

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any common allergens or parabens

What's Inside

They both contain harsh alcohols

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Resurfacing Retinol Serum
Acne Defense Prebio Serum

Water

Skin Conditioning

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Sclerotium Gum

Emulsion Stabilising

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Caprylhydroxamic Acid

Croton Lechleri Resin Extract

Skin Conditioning

Aloe Barbadensis Leaf Juice

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Mannitol

Humectant
Helps hydrate Dry Skin Icon

Cellulose

Absorbent

Hydroxypropyl Methylcellulose

Emulsion Stabilising

Inulin

Skin Conditioning

Yeast Beta-Glucan

Skin Conditioning

Undaria Pinnatifida Extract

Skin Conditioning

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

PEG-40 Hydrogenated Castor Oil

Emulsifying
Oil IconNot safe for Fungal Acne Icon

Melaleuca Alternifolia Leaf Oil

Antioxidant
Antioxidant IconFragrance IconOil IconHelps hydrate Dry Skin IconGood for Oily Skin IconMay worsen Eczema Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Lactobacillus/Rye Flour Ferment

Skin Conditioning

Saccharide Isomerate

Humectant
Helps hydrate Dry Skin Icon

Xanthan Gum

Emulsifying

Glucose

Humectant
Helps hydrate Dry Skin Icon

Chondrus Crispus Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Hydroxypropyltrimonium Hyaluronate

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Scar Healing Icon

Potassium Hyaluronate

Skin Conditioning

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Houttuynia Cordata Extract

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Glycyrrhiza Glabra Root Extract

Bleaching
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Scutellaria Baicalensis Root Extract

Astringent

Pistacia Lentiscus Gum

Masking

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Morus Alba Root Extract

Bleaching

Artemisia Capillaris Flower Extract

Skin Conditioning

Ziziphus Jujuba Fruit Extract

Skin Conditioning

Taraktogenos Kurzii Seed Oil

Skin Conditioning
1 / 0 Oil Icon

Nigella Sativa Seed Oil

Emollient
Fragrance IconOil Icon

Leptospermum Scoparium Branch/Leaf Oil

Tonic
Oil Icon

Potassium Lauroyl Wheat Amino Acids

Cleansing

Palm Glycerides

Emollient
Not safe for Fungal Acne Icon

Capryloyl Glycine

Cleansing

Magnolia Grandiflora Bark Extract

Antimicrobial
Antioxidant Icon

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Polygonum Cuspidatum Root Extract

Antioxidant
Antioxidant Icon

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Chamomilla Recutita Flower Extract

Masking
Helps reduce Skin Redness IconHelps reduce irritation Icon

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Phenoxyethanol

Preservative
Preservative Icon

Sodium Benzoate

Masking
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Sodium Citrate

Buffering

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Antimicrobial, Astringent, Masking

Alcohol comes in many different forms. Different types of alcohol will have different effects on skin. This ingredient is usually an astringent alcohol.

These alcohols are drying on the skin. They may strip away your skin's natural oils and even damage your skin barrier. Astringent alcohols may also irritate skin.

Other types of astringent alcohols include:

According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.

Any type of sanitizing product will have high amounts of alcohol to help kill bacteria and viruses.

Fatty alcohols come from plant oils such as coconut oil. These can help hydrate the skin and are non-irritating. Some fatty alcohols include cetyl and stearyl alcohol.

Learn more about Alcohol
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Skin Conditioning

Ceramide AP is a type of Ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. Having a strong skin barrier leads to more firm and hydrated skin.

They are known for their ability to hold water and thus are a great ingredient for dry skin. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here:
Ceramide NP
Ceramide EOP

Learn more about Ceramide AP
Buffering, Masking

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.

If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.

Read more about some other popular AHA's here:

Learn more about Citric Acid
Humectant, Skin Conditioning

Dipotassium Glycyrrhizate comes from licorice root.

Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Learn more about Dipotassium Glycyrrhizate
Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.

This ingredient has emollient and emulsifying properties.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Some other names for this ingredient include soy lecithin and deoiled soy lecithin.

Learn more about Lecithin
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Emulsifying

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Buffering, Masking

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

Its main functions are to maintain the pH of a product and neutralize metal ions.

The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).

Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Learn more about Sodium Citrate
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

When to use

2,669 Routines
8% use in am
92% use in pm
68% use every day
When to use See routines that use it ->
57 Routines
42% use in am
58% use in pm
88% use every day
When to use See routines that use it ->

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