Skinstitut Retinol Serum Versus Medik8 Crystal Retinal - 1
Updated on June 18, 2025
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 9 ingredients in common
Cool Features
They both contain hyaluronic acid, retinoid and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any parabens or sulfates
What's Inside
They both contain common allergens, fragrances and oils
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Skinstitut Retinol Serum 50 ingredients
Medik8 Crystal Retinal 43 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Skinstitut Retinol Serum 50 ingredients
Medik8 Crystal Retinal 43 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCyclopentasiloxane
Emollient
Glycerin
Humectant
Polysorbate 60
Emulsifying
Pistacia Vera Seed Oil
Skin Conditioning
Ethoxydiglycol
HumectantHydrogenated Ethylhexyl Olivate
EmollientSodium Hyaluronate
Humectant
Tocopherol
Antioxidant
Hydrolyzed Vegetable Protein
Skin ConditioningHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingSqualane
Emollient
Hydrogenated Olive Oil Unsaponifiables
Emollient
Dimethicone Crosspolymer
Emulsion Stabilising
Arginine
Masking
Trehalose
Humectant
Phenoxyethanol
Preservative
Caprylyl Glycol
EmollientDisodium Adenosine Triphosphate
Skin ConditioningMannitol
Humectant
Pyridoxine Hcl
Skin ConditioningRna
Skin ConditioningMoringa Oleifera Leaf Extract
Skin ConditioningParfum
Masking
Alcohol
Antimicrobial
Histidine Hcl
Skin ConditioningEpilobium Angustifolium Leaf Extract
Skin ConditioningDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Tetrahydropiperine
Skin ConditioningRetinol
Skin Conditioning
Phenylalanine
Masking
Panthenol
Skin Conditioning
Citric Acid
Buffering
Sorbic Acid
Preservative
Sodium Hydroxide
BufferingRuscus Aculeatus Root Extract
AstringentCentella Asiatica Extract
Cleansing
Calendula Officinalis Flower Extract
Masking
Aesculus Hippocastanum Extract
Antioxidant
Leontopodium Alpinum Flower Extract
Skin ConditioningTyrosine
MaskingSodium Benzoate
Masking
Heptane
SolventBHT
Antioxidant
Potassium Sorbate
Preservative
Ammonium Glycyrrhizate
MaskingAllyl Methacrylates Crosspolymer
Emulsion StabilisingCitronellol
Perfuming
Geraniol
Perfuming
Linalool
Perfuming
Water, Cyclopentasiloxane, Glycerin, Polysorbate 60, Pistacia Vera Seed Oil, Ethoxydiglycol, Hydrogenated Ethylhexyl Olivate, Sodium Hyaluronate, Tocopherol, Hydrolyzed Vegetable Protein, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Hydrogenated Olive Oil Unsaponifiables, Dimethicone Crosspolymer, Arginine, Trehalose, Phenoxyethanol, Caprylyl Glycol, Disodium Adenosine Triphosphate, Mannitol, Pyridoxine Hcl, Rna, Moringa Oleifera Leaf Extract, Parfum, Alcohol, Histidine Hcl, Epilobium Angustifolium Leaf Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Tetrahydropiperine, Retinol, Phenylalanine, Panthenol, Citric Acid, Sorbic Acid, Sodium Hydroxide, Ruscus Aculeatus Root Extract, Centella Asiatica Extract, Calendula Officinalis Flower Extract, Aesculus Hippocastanum Extract, Leontopodium Alpinum Flower Extract, Tyrosine, Sodium Benzoate, Heptane, BHT, Potassium Sorbate, Ammonium Glycyrrhizate, Allyl Methacrylates Crosspolymer, Citronellol, Geraniol, Linalool
Water
Skin ConditioningCaprylic/Capric Triglyceride
Masking
Glycerin
Humectant
Isododecane
EmollientCetearyl Olivate
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingCetearyl Alcohol
Emollient
PPG-12/Smdi Copolymer
EmollientSorbitan Olivate
Emulsifying
Tocopheryl Acetate
Antioxidant
Squalane
Emollient
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingHydroxyacetophenone
Antioxidant
Cyclodextrin
Absorbent3-O-Ethyl Ascorbic Acid
Skin Conditioning
Sodium Polyaspartate
HumectantHydroxypropyl Methylcellulose
Emulsion StabilisingSodium Hyaluronate
Humectant
Phenoxyethanol
Preservative
Tetrahexyldecyl Ascorbate
Antioxidant
Daucus Carota Sativa Seed Oil
Emollient
Retinal
Skin Conditioning
Alumina
Abrasive
Isostearic Acid
Cleansing
Lecithin
Emollient
Polyglyceryl-3 Polyricinoleate
Emulsifying
Polyhydroxystearic Acid
Emulsifying
Lonicera Japonica Flower Extract
Skin ConditioningLonicera Caprifolium Flower Extract
Perfuming
Stearic Acid
Cleansing
Citric Acid
Buffering
BHT
Antioxidant
Rubus Chamaemorus Seed Oil
Skin Conditioning
Polysorbate 60
Emulsifying
Disodium EDTA
Ethylhexylglycerin
Skin ConditioningSorbitan Isostearate
Emulsifying
Pentylene Glycol
Skin ConditioningVanilla Planifolia Fruit Extract
Skin Conditioning
Dipteryx Odorata Bean Extract
Masking
Coumarin
Perfuming
CI 14700
Cosmetic ColorantCI 77891
Cosmetic ColorantWater, Caprylic/Capric Triglyceride, Glycerin, Isododecane, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, PPG-12/Smdi Copolymer, Sorbitan Olivate, Tocopheryl Acetate, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyacetophenone, Cyclodextrin, 3-O-Ethyl Ascorbic Acid, Sodium Polyaspartate, Hydroxypropyl Methylcellulose, Sodium Hyaluronate, Phenoxyethanol, Tetrahexyldecyl Ascorbate, Daucus Carota Sativa Seed Oil, Retinal, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Stearic Acid, Citric Acid, BHT, Rubus Chamaemorus Seed Oil, Polysorbate 60, Disodium EDTA, Ethylhexylglycerin, Sorbitan Isostearate, Pentylene Glycol, Vanilla Planifolia Fruit Extract, Dipteryx Odorata Bean Extract, Coumarin, CI 14700, CI 77891
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
BHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTCitric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinThis is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Learn more about Polysorbate 60Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateSqualane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan?
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Is squalane an oil?
Squalane is often called an oil, but it’s technically not; it’s a hydrocarbon, meaning it’s only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.
The term “oil-free” isn’t regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. It’s worth testing out simple oils or squalane to see what works best for your skin.
Learn more about SqualaneWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Skinstitut Retinol Serum 50 ingredients
Medik8 Crystal Retinal 43 ingredients
Reviews
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