SkinBetter Science Alto Advanced Defense and Repair Serum Versus Face Reality Skincare Vitamin A Corrective II Serum
This barrier-repair serum is formulated around Niacinamide to strengthen the skin barrier and calm redness.
This anti-aging serum is formulated around Retinol and Palmitoyl Tripeptide-38 to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
Humectant
Propanediol
Solvent
Ethylhexyl Olivate
Skin Conditioning
Cetearyl Alcohol
Emollient
Chlorogenic Acids
Antioxidant
Niacinamide
Smoothing
Lauryl Lactate
EmollientDimethyl Isosorbide
SolventPyrroloquinoline Quinone Allyl Ester
Antioxidant
Hydrolyzed Sodium Hyaluronate
Skin Conditioning
Glycyrrhiza Glabra Root Extract
Bleaching
Tetrahexyldecyl Ascorbate
Antioxidant
Ergothioneine
Antioxidant
Benzylidene Dimethoxydimethylindanone
Skin ProtectingArabidopsis Thaliana Extract
Antioxidant
Carnosine
Skin Conditioning
Camellia Sinensis Leaf Extract
Antimicrobial
Vitis Vinifera Seed Extract
Antimicrobial
Theobroma Cacao Seed Extract
Antioxidant
Curcuma Longa Root Extract
Antioxidant
Olea Europaea Fruit Extract
BleachingEuterpe Oleracea Fruit Extract
Trifluoroacetyl Tripeptide-2
Skin Conditioning
Buddleja Officinalis Flower Extract
UV FilterCoffea Arabica Leaf Cell Extract
Antioxidant
Crocus Sativus Leaf Cell Culture Extract
Skin ProtectingSuperoxide Dismutase
Antioxidant
Ubiquinone
Antioxidant
Plankton Extract
Skin ConditioningMicrococcus Lysate
Skin ConditioningArginine
Masking
Zingiber Officinale Root Extract
Masking
Ceramide NP
Skin Conditioning
Ceramide AP
Skin Conditioning
Ceramide EOP
Skin Conditioning
Linoleic Acid
Cleansing
Linolenic Acid
Cleansing
Sea Whip Extract
Skin ConditioningBisabolol
Antioxidant
Tocopherol
Antioxidant
Tocopheryl Acetate
Antioxidant
Cholesterol
Emollient
Phytosphingosine
Skin Conditioning
Jojoba Esters
Emollient
Sodium PCA
Humectant
Pentylene Glycol
Skin Conditioning
Methyl Gluceth-20
Humectant
Glycerin
Humectant
Helianthus Annuus Seed Wax
Skin Conditioning
Acacia Decurrens Flower Wax
Emollient
Lecithin
Emollient
Sodium Lauroyl Lactylate
EmulsifyingDicetyl Phosphate
EmulsifyingPropanediol Dicaprylate/Caprate
EmollientPolyglycerin-3
Humectant
Ceteth-20 Phosphate
CleansingDiisostearyl Malate
EmollientXanthan Gum
EmulsifyingSteareth-2
EmulsifyingAcacia Senegal Gum
MaskingPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Antioxidant
Carbomer
Emulsion StabilisingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingDextran
Ricinoleth-40
CleansingSodium Hydroxide
BufferingCitric Acid
Buffering
Sodium Phytate
Ethylhexylglycerin
Skin ConditioningPhenoxyethanol
Preservative
Water, Butylene Glycol, Propanediol, Ethylhexyl Olivate, Cetearyl Alcohol, Chlorogenic Acids, Niacinamide, Lauryl Lactate, Dimethyl Isosorbide, Pyrroloquinoline Quinone Allyl Ester, Hydrolyzed Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract, Tetrahexyldecyl Ascorbate, Ergothioneine, Benzylidene Dimethoxydimethylindanone, Arabidopsis Thaliana Extract, Carnosine, Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Extract, Theobroma Cacao Seed Extract, Curcuma Longa Root Extract, Olea Europaea Fruit Extract, Euterpe Oleracea Fruit Extract, Trifluoroacetyl Tripeptide-2, Buddleja Officinalis Flower Extract, Coffea Arabica Leaf Cell Extract, Crocus Sativus Leaf Cell Culture Extract, Superoxide Dismutase, Ubiquinone, Plankton Extract, Micrococcus Lysate, Arginine, Zingiber Officinale Root Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Linoleic Acid, Linolenic Acid, Sea Whip Extract, Bisabolol, Tocopherol, Tocopheryl Acetate, Cholesterol, Phytosphingosine, Jojoba Esters, Sodium PCA, Pentylene Glycol, Methyl Gluceth-20, Glycerin, Helianthus Annuus Seed Wax, Acacia Decurrens Flower Wax, Lecithin, Sodium Lauroyl Lactylate, Dicetyl Phosphate, Propanediol Dicaprylate/Caprate, Polyglycerin-3, Ceteth-20 Phosphate, Diisostearyl Malate, Xanthan Gum, Steareth-2, Acacia Senegal Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dextran, Ricinoleth-40, Sodium Hydroxide, Citric Acid, Sodium Phytate, Ethylhexylglycerin, Phenoxyethanol
Water
Skin ConditioningCaprylic/Capric Triglyceride
Masking
Glycerin
Humectant
Dimethyl Isosorbide
SolventAmmonium Acryloyldimethyltaurate/Vp Copolymer
Tapioca Starch
Phenoxyethanol
Preservative
Retinol
Skin Conditioning
Polysorbate 20
Emulsifying
Sodium Stearoyl Glutamate
CleansingCyclodextrin
AbsorbentSodium Gluconate
Skin ConditioningO-Cymen-5-Ol
Antimicrobial
Ethylhexylglycerin
Skin ConditioningPentylene Glycol
Skin Conditioning
Methylglucoside Phosphate
Skin ConditioningCopper Lysinate/Prolinate
Skin ConditioningHydroxypropyl Cyclodextrin
MaskingPalmitoyl Tripeptide-38
Skin Conditioning
Caprylyl Glycol
Emollient
N-Prolyl Palmitoyl Tripeptide-56 Acetate
Skin Conditioning
Water, Caprylic/Capric Triglyceride, Glycerin, Dimethyl Isosorbide, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Tapioca Starch, Phenoxyethanol, Retinol, Polysorbate 20, Sodium Stearoyl Glutamate, Cyclodextrin, Sodium Gluconate, O-Cymen-5-Ol, Ethylhexylglycerin, Pentylene Glycol, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38, Caprylyl Glycol, N-Prolyl Palmitoyl Tripeptide-56 Acetate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Dimethyl Isosorbide (often shortened to DMI) is a sugar-derived solvent made from sorbitol. It's used to dissolve tricky ingredients and help them mix smoothly into a formula.
Many actives sit as gritty crystals when undissolved, so DMI swoops in to full dissolve them. This helps improve texture, stability, and how evenly an active is distributed.
It does have a penetration-enhancing reputation that is a bit more nuanced than marketing suggests; a cell study on human skin found that 10% DMI didn't significantly boost the permeation of Hydroquinone, Salicylic Acid, or Octadecenedioic Acid compared to controls (though it did improve their solubility in the formula itself).
Typical usage concentrations usually range from 1-10% depending on the formula's needs; this ingredient is also well tolerated at these levels.
Learn more about Dimethyl IsosorbideEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
