Versus

SKIN1004 Retinol 0.2 Boosting Shot Ampoule Versus KISOCare Retinol Cream 0.4

Ampoule
Night Moisturizer
Korean Brand South Korea
Japanese Brand Japan

Updated on August 18, 2025

Overview

What they are

These products are both reef safe . They have a total of 11 ingredients in common

Cool Features

They both contain hyaluronic acid, retinoid and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Retinol Cream 0.4

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Octyldodecyl Myristate

Emollient

Methylheptyl Laurate

Emollient

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Hydrogenated Rapeseed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Pentylene Glycol

Skin Conditioning

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Dodecane

Perfuming
Fragrance IconNot safe for Fungal Acne Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Hydroxypinacolone Retinoate

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Tocopheryl Retinoate

Antioxidant
Retinoid IconAntioxidant IconGood for Oily Skin Icon

Retinyl Palmitate

Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Hydrogenated Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Argania Spinosa Kernel Oil

Emollient
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconNot safe for Fungal Acne Icon

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconGood for Scar Healing IconNot safe for Fungal Acne Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Arachis Hypogaea Oil

Skin Conditioning
2 / 0 Oil IconNot safe for Fungal Acne Icon

Phytosterols

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Ceramide Ng

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide Ag

Humectant
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide 2

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide 1

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide 3

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide 4

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide 5

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide EOP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Oligopeptide-1

Skin Conditioning
Peptide Icon

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Hyaluronic Acid/Polyglutamic Acid Crosspolymer

Antioxidant
Hyaluronic Acid IconAntioxidant IconHelps hydrate Dry Skin Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Scar Healing Icon

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Orange Roughy Oil

Skin Conditioning
Oil Icon

Salvia Sclarea Oil

Masking
Oil Icon

Rose Flower Oil

Masking
Oil IconMay cause irritation IconEU Allergen Icon

Lavandula Angustifolia Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Pelargonium Graveolens Oil

Masking
Fragrance IconOil IconMay cause irritation Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Scutellaria Baicalensis Root Extract

Astringent

(Licorice/Reynoutria Japonica) Root/Stem Extract

Antioxidant
Antioxidant Icon

Glycyrrhiza Glabra Root Extract

Bleaching
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Melaleuca Alternifolia Leaf Extract

Perfuming
Fragrance IconGood for Oily Skin Icon

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Anthemis Nobilis Flower Extract

Masking
Fragrance IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Glyceryl Behenate

Emollient
Not safe for Fungal Acne Icon

Polyglyceryl-6 Octastearate

Emulsifying

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Decyltetradeceth-20

Emulsifying

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Sodium Citrate

Buffering

Dimethyl Isosorbide

Solvent

Ethylhexylglycerin

Skin Conditioning

Calcium Sodium Borosilicate

Silver Oxide

Antimicrobial

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Cleansing, Skin Conditioning, Smoothing

Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.

Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.

Studies show the compounds in centella help with:

The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.

Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Extract
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Skin Conditioning

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Why is retinol famous?

It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.

Retinol is proven to:

This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.

Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

Learn more about Retinol
Antimicrobial, Masking, Skin Conditioning

Rosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.

While Rosmarinus Officinalis Leaf Oil can be volatile due to its fragrant properties, the fragrance components are usually removed in the leaf extract.

Rosemary Leaf Extract contains many antioxidants such as rosmarinic acid and caffeic acid. Rosemarinic acid, a compound found in rosemary leaf, has been found to help soothe skin conditions such as eczema and acne.

Learn more about Rosmarinus Officinalis Leaf Extract
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Is squalane an oil?

Squalane is often called an oil, but it’s technically not; it’s a hydrocarbon, meaning it’s only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.

The term “oil-free” isn’t regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. It’s worth testing out simple oils or squalane to see what works best for your skin.

Learn more about Squalane
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

49 Routines
4% use in am
94% use in pm
63% use every day
When to use See routines that use it ->
1 Routine
0% use in am
100% use in pm
100% use every day

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Absorbs Well 100% Expensive 100% Irritating 100%

KISOCare Retinol Cream 0.4 62 ingredients

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