One Thing Niacinamide Glutathione Serum Versus APLB Glutathione Niacinamide Ampoule Serum
Updated on April 21, 2025
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 15 ingredients in common
Cool Features
They both contain hyaluronic acid and niacinamide
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates
What's Inside
They both contain fragrances
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
One Thing Niacinamide Glutathione Serum 33 ingredients
APLB Glutathione Niacinamide Ampoule Serum 45 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
One Thing Niacinamide Glutathione Serum 33 ingredients
APLB Glutathione Niacinamide Ampoule Serum 45 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamideButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about Propanediol1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Hydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.
This ingredient is not irritating or sensitizing.
Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAGlutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.
As an antioxidant, it prevents oxidative damage to parts of our cell.
While glutathione is said to help with fading dark spots, the results from research are inconclusive. Further studies are needed. With that said, gluthatione has been shown to protect our skin from UV-B induced damage.
This ingredient is naturally occurring in plants, animals, fungi, and some bacteria.
Learn more about GlutathioneSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateMelaleuca Alternifolia Leaf Extract comes from the Tea Tree, Melaleuca alternifolia, Myrtaceae. This tea tree is native to Australia.
Tea Leaf extract contains antimicrobial and anti-acne properties.
Tea tree extract is fragrant and contains volatiles such as linalool and limonene. These fragrance and terpinen components can cause skin sensitivity.
Learn more about the benefits of Tea Tree Oil here.
Learn more about Melaleuca Alternifolia Leaf ExtractGlucose is a simple sugar and is the most important source of energy in all organisms.
In skincare, glucose is used to hydrate the skin. It also acts as a prebiotic for our natural biome.
Glucose is hydrating due to its humectant property. As a humectant, glucose draws moisture from the air and from deeper levels in the skin.
Our skin contains many sugars that act as prebiotics and help strengthen our natural microbiome. Having a healthy microbiome helps protect our skin from harmful bacteria and other contaminants.
Studies show glucose may help with fading discoloration and pigmentation. This is because our skin metabolizes glucose into lactic acid. Lactic acid is an AHA that helps exfoliate the top layer of skin.
Learn more about GlucoseIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
One Thing Niacinamide Glutathione Serum 33 ingredients
APLB Glutathione Niacinamide Ampoule Serum 45 ingredients

Reviews
Here's what our community thinks
One Thing Niacinamide Glutathione Serum 33 ingredients
APLB Glutathione Niacinamide Ampoule Serum 45 ingredients
I've been using APLB's Glutathione Niacinamide serum twice a day for several months, targeting dark spots and hyperpigmentation, and I don’t regret buying it.
Assessing the impact of a specific product or ingredient can be challenging, given that my routine includes several brightening products. The results are likely a cumulative effect. However, since this serum is one of my newest additions, Show more