Numbuzin No.1 Pantothenic B5 Active Soothing Cream Versus La Roche-Posay Effaclar Duo+M
Updated on February 20, 2025
Overview
What they are
These products are both reef safe general moisturizers. They have a total of 7 ingredients in common
Cool Features
They both contain exfoliants and niacinamide
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, common allergens, parabens or sulfates
What's Inside
They both contain fragrances and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Numbuzin No.1 Pantothenic B5 Active Soothing Cream 59 ingredients
La Roche-Posay Effaclar Duo+M 35 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Numbuzin No.1 Pantothenic B5 Active Soothing Cream 59 ingredients
La Roche-Posay Effaclar Duo+M 35 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamidePentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolSilica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.
Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.
Silica is present naturally within the skin during collagen production and when reducing inflammation.
Learn more about SilicaZinc PCA (or "zinc salt") differs slightly from zinc itself. PCA stands for pyrrolidone carboxylic acid. However, Zinc PCA comes from zinc.
It can help reduce redness, regulate sebum, and promote the general healing process of the skin.
Zinc PCA tends to be especially useful for those with oily, acne-prone skin. It's certainly an ingredient worth trying out!
Learn more about Zinc PCAXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Numbuzin No.1 Pantothenic B5 Active Soothing Cream 59 ingredients
La Roche-Posay Effaclar Duo+M 35 ingredients


Reviews
Here's what our community thinks
Numbuzin No.1 Pantothenic B5 Active Soothing Cream 59 ingredients
- made me break out
- made my chin area itchy
- not hydrating enougg