Piroctone Olamine
Explained
Piroctone Olamine is a synthetic antifungal and preservative ingredient.
Its main job is to keep the yeast, Malassezia, in check; this yeast is linked to dandruff, seborrheic dermatitis, and fungal acne (a.k.a. Malassezia folliculitis).
The way it works is pretty neat:
It slips into the fungal cell and grabs onto iron ions that the yeast needs for its energy metabolism; this basically starves it out. But the full mechanism isn't 100% pinned down and some research also points it to interfering with ergosterol (a building block of the fungal cell membrane).
Besides antifungal action, it also has mild anti-inflammatory and soothing effects to help calm itchiness in the scalp.
Typical usage concentrations are low. The EU permits it to be a preservative up to 1% in rinse-off products and 0.5% in leave-on products.
Though it's generally well-tolerated, a small number of people may notice itching or irritation (as with any active).
See all 633 products with Piroctone Olamine
