Nineless 10% Niacinamide Serum Versus D'You Hustle
What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Skin ConditioningNiacinamide
SmoothingMethylpropanediol
SolventGlycerin
HumectantPanthenol
Skin ConditioningTranexamic Acid
Astringent1,2-Hexanediol
Skin ConditioningHippophae Rhamnoides Extract
MaskingAscorbyl Glucoside
AntioxidantDipropylene Glycol
HumectantHydroxyacetophenone
AntioxidantGlutathione
Butylene Glycol
HumectantCaprylyl Glycol
EmollientCarbomer
Emulsion StabilisingArginine
MaskingTocopherol
AntioxidantGlycereth-26
HumectantDisodium EDTA
Betaine
HumectantPhellodendron Amurense Bark Extract
Skin ConditioningAstragalus Membranaceus Root Extract
EmollientScutellaria Baicalensis Root Extract
AstringentCoptis Chinensis Root Extract
AntioxidantBisabolol
AntioxidantDipotassium Glycyrrhizate
HumectantSodium Hyaluronate
HumectantEthylhexylglycerin
Skin ConditioningHexapeptide-9
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningAcetyl Hexapeptide-8
HumectantNonapeptide-1
Skin ConditioningWater, Niacinamide, Methylpropanediol, Glycerin, Panthenol, Tranexamic Acid, 1,2-Hexanediol, Hippophae Rhamnoides Extract, Ascorbyl Glucoside, Dipropylene Glycol, Hydroxyacetophenone, Glutathione, Butylene Glycol, Caprylyl Glycol, Carbomer, Arginine, Tocopherol, Glycereth-26, Disodium EDTA, Betaine, Phellodendron Amurense Bark Extract, Astragalus Membranaceus Root Extract, Scutellaria Baicalensis Root Extract, Coptis Chinensis Root Extract, Bisabolol, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Ethylhexylglycerin, Hexapeptide-9, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Hexapeptide-8, Nonapeptide-1
Water
Skin ConditioningBetula Platyphylla Japonica Juice
Skin ConditioningGlycerin
HumectantPropanediol
SolventNiacinamide
SmoothingGalactomyces Ferment Filtrate
HumectantBifida Ferment Lysate
Skin Conditioning1,2-Hexanediol
Skin ConditioningIsononyl Isononanoate
EmollientAscorbyl Glucoside
AntioxidantPanthenol
Skin ConditioningAscorbyl Tetraisopalmitate
Antioxidant3-O-Ethyl Ascorbic Acid
Skin ConditioningResveratrol
AntioxidantTocopherol
AntioxidantHydrolyzed Hyaluronic Acid
HumectantPolyglutamic Acid
Skin ConditioningTromethamine
BufferingGlycolipids
Skin ConditioningPolyglyceryl-10 Oleate
Skin ConditioningHydroxyethylcellulose
Emulsion StabilisingButylene Glycol
HumectantHexapeptide-2
BleachingPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingXanthan Gum
EmulsifyingPolyacrylate Crosspolymer-6
Emulsion StabilisingEthylhexylglycerin
Skin ConditioningAdenosine
Skin ConditioningPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantTris(Tetramethylhydroxypiperidinol)Citrate
StabilisingSodium Nitrate
SoothingT-Butyl Alcohol
PerfumingGlyoxal
AntimicrobialSqualane
EmollientSimmondsia Chinensis Seed Oil
EmollientOenothera Biennis Oil
EmollientVitis Vinifera Seed Oil
EmollientRosa Canina Fruit Oil
EmollientRicinus Communis Seed Oil
MaskingCarbomer
Emulsion StabilisingSodium Lactate
BufferingPolysorbate 20
EmulsifyingAlcohol
AntimicrobialDisodium EDTA
Parfum
MaskingWater, Betula Platyphylla Japonica Juice, Glycerin, Propanediol, Niacinamide, Galactomyces Ferment Filtrate, Bifida Ferment Lysate, 1,2-Hexanediol, Isononyl Isononanoate, Ascorbyl Glucoside, Panthenol, Ascorbyl Tetraisopalmitate, 3-O-Ethyl Ascorbic Acid, Resveratrol, Tocopherol, Hydrolyzed Hyaluronic Acid, Polyglutamic Acid, Tromethamine, Glycolipids, Polyglyceryl-10 Oleate, Hydroxyethylcellulose, Butylene Glycol, Hexapeptide-2, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Polyacrylate Crosspolymer-6, Ethylhexylglycerin, Adenosine, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Tris(Tetramethylhydroxypiperidinol)Citrate, Sodium Nitrate, T-Butyl Alcohol, Glyoxal, Squalane, Simmondsia Chinensis Seed Oil, Oenothera Biennis Oil, Vitis Vinifera Seed Oil, Rosa Canina Fruit Oil, Ricinus Communis Seed Oil, Carbomer, Sodium Lactate, Polysorbate 20, Alcohol, Disodium EDTA, Parfum
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Ascorbyl Glucoside is a stable form of Vitamin C. It is created by combining glucose from starch.
When applied to skin, Ascorbyl Glucoside turns into Ascorbic Acid.
Ascorbyl Glucoside is an antioxidant. Antioxidants help fight free-radicals, or molecules that may damage skin cells.
It can help to reduce redness, improve skin texture, reduce the effects of aging, reduce the visibility of dark spots, and brighten skin.
Read more about other types of Vitamin C:
Learn more about Ascorbyl GlucosideButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCarbomer is a high-molecular weight polymer of acrylic acid. It is used to form gels and thicken formulas.
Due to its large molecular size, carbomer has minimal skin penetration and is considered an inert ingredient.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Learn more about CarbomerDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamidePalmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).
This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.
Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.
Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.
Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. It’s commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).
Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Palmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.
This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.
By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.
You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.
Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water