Versus

MediCube One Day Zero Exosome Shot - Mild 2000 Versus MediCube Zero Pore One-Day Cream

Ampoule
General Moisturizer
Korean Brand South Korea
Korean Brand South Korea

Updated on April 11, 2025

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 13 ingredients in common

Cool Features

They both contain BHA and niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Zero Pore One-Day Cream

Water

Skin Conditioning

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Cetyl Ethylhexanoate

Emollient

Octyldodecanol

Emollient

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Isohexadecane

Emollient

Isododecane

Emollient

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Polyglyceryl-3 Distearate

Emulsifying
Not safe for Fungal Acne Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Hydrogenated Poly(C6-14 Olefin)

Emollient

Dimethicone

Emollient
1 / 0 Silicon Icon

Cyclopentasiloxane

Emollient
Silicon Icon

Cetearyl Olivate

Not safe for Fungal Acne Icon

Sorbitan Olivate

Emulsifying
Not safe for Fungal Acne Icon

Stearyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Dimethyl Sulfone

Solvent
Good for Oily Skin IconHelps fight Acne Icon

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Polyacrylate-13

Sodium Polyacryloyldimethyl Taurate

Emulsion Stabilising

Sodium Stearoyl Glutamate

Cleansing

Hydrogenated Polyisobutene

Emollient
1 / 2

Glyceryl Stearate Citrate

Emollient
Not safe for Fungal Acne Icon

Salicylic Acid

Masking
BHA IconPreservative IconGood for Oily Skin IconGood for Minimizing Pores IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Ethylhexylglycerin

Skin Conditioning

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Ethylhexyl Palmitate

Emollient
2-3 / 0 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Dextrin

Absorbent

Sorbitan Isostearate

Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon

Tromethamine

Buffering

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Scar Healing Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Citrate

Buffering

Gardenia Florida Fruit Extract

Skin Conditioning

Myristyl Alcohol

Emollient
2 / 4 Fatty Alcohol Icon

Trisodium Phosphate

Buffering

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Pullulan

Lauryl Alcohol

Emollient
Fatty Alcohol Icon

Vitis Vinifera Fruit Extract

Skin Conditioning

Ulmus Davidiana Root Extract

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Pueraria Lobata Root Extract

Humectant

Pinus Palustris Leaf Extract

Tonic

Oenothera Biennis Flower Extract

Astringent

Diospyros Kaki Fruit Extract

Skin Conditioning

Castanea Crenata Shell Extract

Skin Conditioning

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Scar Healing Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Palmitoyl Tripeptide-5

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Hydroxypropyltrimonium Hyaluronate

Hydroxycinnamic Acid

Skin Conditioning

Rutin

Antioxidant
Antioxidant Icon

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide

Ethylhexyl Palmitate is created from 2-ethylhexyl alcohol and palmitic acid. It is a fatty acid ester.

The fatty acid content of Ethylhexyl Palmitate makes it an emollient. Emollients help soften and hydrate your skin by trapping moisture within.

Ethylhexyl Palmitate is also used to help improve the texture of cosmetics. It helps other ingredient dissolve in products and help disperse ingredients more evenly.

You'll likely find this ingredient in sunscreen, as it is often used to mix UV-blocking ingredients such as avobenzone and ethylhexyl triazone.

It can also help stabilize the fragrances in a product as a fragrance fixative.

Ethylhexyl Palmitate can be used to substitute mineral oil.

Due to its high fatty acid content, it may not be fungal-acne safe.

Learn more about Ethylhexyl Palmitate
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol

We don't have a description for Pueraria Lobata Root Extract yet.

We don't have a description for Pinus Palustris Leaf Extract yet.

We don't have a description for Oenothera Biennis Flower Extract yet.

Skin Conditioning

This tree is also known as the David Elm. It contains the ingredient bakuchiol.

Other great compounds found in this ingredient include galactose, glucose, and phenolics. The sugar content gives it great skin hydrating properties. Phenolics are potent antioxidants commonly found in fruits and veggies.

A 2020 study found the phenolics of this root to have an anti-inflammatory effect.

Fun fact: This ingredient is used in traditional Asian medicine.

Learn more about Ulmus Davidiana Root Extract

When to use

24 Routines
29% use in am
71% use in pm
75% use every day
30 Routines
43% use in am
57% use in pm
77% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

MediCube One Day Zero Exosome Shot 27 ingredients

3.0 /5
from 1 rating
Absorbs Well (1) Hydrating (1) Light (1)

MediCube Zero Pore One-Day Cream 61 ingredients

5.0 /5
from 1 rating
Hydrating (1) Light (1) Light Scent (1)
izumireed's avatar

Izumi Reed

7 months ago
Review

It showed as 52 percent match to my skin type, but this really works for my skin. I have oily skin. My skin feels nice in the morning.

#hydrating
#light
#light scent
#works well