Versus

ma:nyo Bifida Biome Ampoule Mask Versus ma:nyo Bifida Biome Complex Ampoule

Sheet Mask
Ampoule
Korean Brand South Korea
Korean Brand South Korea

Updated on September 23, 2024

Overview

What they are

These products are both vegan, cruelty-free, and reef safe . They have a total of 25 ingredients in common

Cool Features

They both contain hyaluronic acid and niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Ingredients Side-by-side

found in both products
Bifida Biome Ampoule Mask

Water

Skin Conditioning

Methylpropanediol

Solvent

1,2-Hexanediol

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin Icon

Lactobacillus Ferment Lysate

Skin Conditioning
Not safe for Fungal Acne Icon

Lactococcus Ferment Lysate

Skin Conditioning

Saccharomyces Ferment Filtrate

Humectant

Lactobacillus Ferment

Skin Conditioning

Chrysanthemum Zawadskii Extract

Skin Conditioning

Glycyrrhiza Uralensis Root Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Anastatica Hierochuntica Extract

Astringent

Artemisia Capillaris Extract

Hamamelis Virginiana Water

Astringent
Can worsen Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Leonurus Sibiricus Extract

Skin Conditioning

Paeonia Albiflora Flower Extract

Tonic

Hydroxyethyl Urea

Humectant

Tromethamine

Buffering

Cynanchum Atratum Extract

Skin Conditioning

Oenothera Biennis Flower Extract

Astringent

Madecassoside

Antioxidant
Antioxidant IconHelps reduce irritation IconHelps with Anti-Aging Icon

Isoleucine

Skin Conditioning

Histidine

Humectant

Cysteine

Antioxidant
Antioxidant Icon

Cyperus Rotundus Root Extract

Skin Conditioning

Aspartic Acid

Masking

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Dextrin

Absorbent

Sodium Phytate

Propanediol

Solvent

Glycine

Buffering
Helps hydrate Dry Skin Icon

Serine

Masking

Glutamic Acid

Humectant

Theobroma Cacao Seed Extract

Antioxidant
Antioxidant Icon

Althaea Rosea Flower Extract

Skin Conditioning

Ethylhexylglycerin

Skin Conditioning

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Polyglyceryl-10 Myristate

Skin Conditioning
Not safe for Fungal Acne Icon

Leucine

Skin Conditioning

Alanine

Masking

Lysine

Skin Conditioning

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Tyrosine

Masking

Phenylalanine

Masking

Proline

Skin Conditioning

Threonine

Valine

Masking

Pinus Palustris Leaf Extract

Tonic

Pueraria Thunbergiana Root Extract

Skin Conditioning

Ulmus Davidiana Root Extract

Skin Conditioning

Methionine

Skin Conditioning

Carbomer

Emulsion Stabilising
1 / 0

Caffeine

Skin Conditioning

Xanthan Gum

Emulsifying

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Cutibacterium Granulosum Ferment Extract Filtrate

Emollient

Bifida Ferment Filtrate

Skin Conditioning
Bifida Biome Complex Ampoule

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Bifida Ferment Filtrate

Skin Conditioning

Lactobacillus Ferment Lysate

Skin Conditioning
Not safe for Fungal Acne Icon

Lactococcus Ferment Lysate

Skin Conditioning

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Skin Conditioning

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Having a healthy microbiome helps protect our skin against infection. It also helps our skin stay hydrated and healthy.

Studies also show this ingredient to be a promising soothing ingredient for sensitive skin.

Learn more about Bifida Ferment Lysate
Skin Conditioning

Lactobacillus Ferment Lysate is a postbiotic with skin soothing properties. Postbiotics are inactive molecules produced by probiotic bacteria that provide skin benefits.

This ingredient comes from the secretion of the bacteria, Lactobacillus.

Studies show this ingredient can help calm redness and may help treat the signs of photoaging; however, the evidence is inconclusive and further studies are needed.

Learn more about Lactobacillus Ferment Lysate
Skin Conditioning

Lactococcus Ferment Lysate is a postbiotic created by fermenting Lactoccus lactis, a type of bacteria more commonly used to create Lactic acid.

Postbiotics are inactive molecules produced by probiotic bacteria that provide skin benefits.

This ingredient offers promising benefits, but it is relatively new and more evidence is needed to prove its efficacy. The manufacturer claims this ingredient:

A study from 2022 found this ingredient helped protect skin against damaged from UV exposure (though this should not replace your sunscreen!).

The lysate in the ingredient name refers to a fluid that forms from breaking down the cell membrane.

Learn more about Lactococcus Ferment Lysate

Saccharomyces Ferment Filtrate is created from fermenting Saccharomyces, a yeast also known as baker's yeast or brewer's yeast.

As a humectant, Saccharomyces Ferment Filtrate helps draw moisture from the air to your skin to keep your skin hydrated. The humectant properties comes from its beta-glucan content.

Humectant, Moisturising, Skin Conditioning

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

This ingredient helps hydrate, soothe, and protect the skin.

What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.

Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.

Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.

Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.

One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.

The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.

These are some other common types of Hyaluronic Acid:

Learn more about Hyaluronic Acid
Humectant, Skin Conditioning

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.

One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.

Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.

Read more about other common forms of hyaluronic acid:

Learn more about Hydrolyzed Hyaluronic Acid
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Buffering, Masking

Tromethamine helps balance the pH and improve the texture of a product. It is synthetically created.

As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.

Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Learn more about Tromethamine
Absorbent

Dextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.

As an emulsifier, dextrin prevents ingredients from separating. This helps elongate a product's shelf life.

Studies show coating UV filters with dextrin prevents these ingredients from being absorbed. This helps UV ingredients last longer on the skin.

Learn more about Dextrin

Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.

Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.

Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol

Theobroma Cacao Seed Extract comes from the Theobroma cacoa, or Cacao tree. Cacao trees are native to tropical landscapes.

Cacao seed extract contains antioxidants known as polyphenols.

Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Skin Conditioning

Polyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.

Polyglyceryl-10 Laurate is a cleansing agent and emulsifier. It helps gather dirt, oil, and other pollutants to be rinsed away. As an emulsifier, it helps prevent ingredients from separating, such as oil and water.

Polyglyceryl-10 Laurate may not be fungal acne safe.

Learn more about Polyglyceryl-10 Laurate
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and is rich in antioxidants.

While caffeine is used to treat cellulite and and dark circles, further studies are needed to prove this. It has been believed to help with these skin conditions due to its ability to dilate blood vessels and increase blood flow.

Some studies are looking into caffeine's ability to protect against UV rays.

Learn more about Caffeine
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine

We don't have a description for Cutibacterium Granulosum Ferment Extract Filtrate yet.

Skin Conditioning

Bifida ferment filtrate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

When to use

2 Routines
0% use in am
100% use in pm
100% use every day
468 Routines
39% use in am
61% use in pm
92% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

ma:nyo Bifida Biome Complex Ampoule 46 ingredients

3.8 /5
from 12 ratings
No Scent (6) Absorbs Well (5) Works Well (4)
samhoover's avatar

Samantha Hoover

5 months ago
Review

I'm in my late 20s and bought this for anti-aging because it's supposed to help with elasticity. But it's too sticky for my liking. It doesn’t irritate my skin and keeps it hydrated, so I’d recommend it for people with dry skin. Elasticity improvement isn’t something you see immediately, and my skin hasn’t lost much elasticity yet. I’m just using it for slow aging, but honestly, I don’t reach for Show more

#hydrating
#heavy
#sticky
#no scent
Tray's avatar

Tray

12 months ago
Review

WRP! I loved this serum. It was hydrating and sunk in well to my skin. My skin felt more plump and supple.

#hydrating
#absorbs well
#no scent
#works well