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Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Because it has a neutral charge, it is compatible with a wide range of ingredients and stays stable across a broad pH range/water hardiness conditions.

Patch testing has shown it to have the lowest irritation potential among common cleansing surfactants (like SLS).

Typical use levels range from 5-20% in rinse-off cleansers.

One thing worth knowing: The American Contact Dermatitis Society named the parent family, alkyl glucosides, "Allergen of the Year" in 2017. The prevalence of allergy is pretty low but be sure to patch test if you've reacted to "gentle" or sulfate-free cleansers before.

This ingredient is fungal acne safe because the fatty alcohol portion of this ingredient is not within the C11-24 chain length that Malassezia can metabolize.

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

This ingredient is considered safe at present practices of use and concentration and repeated insult patch test with 50% Glycol Distearate on 125 subjects found no evidence of skin irritation, hypersensitivity, or acute toxicity.

Typical use concentrations range from 0.1-10%.

Because it's an ester of stearic acid, it falls into the range that Malassezia likes to metabolize. This ingredient may not be fungal acne safe.

Due to the large molecule size, this ingredient is unlikely to penetrate skin.

It's typically used at levels below 5% but can go up to 8.5% in hand cleansers.

Human irritation data for this ingredient looks good: a 2024 study found that Laureth-23 had the lowest irritation score of all the fatty alcohol ethoxylates tested.

Sensitization risk is also low for allergies, the CIR found:

The only notable finding was slight irritation of the clear membrane in the eyes of rabbits so that's worth knowing for eye-area products.

There is one caveat for this whole ingredient family: ethoxylated surfactants slowly oxidize when exposed to air, and it's the oxidation products, not the fresh material, that act as sensitizers.

A study that patch tested 528 dermatitis patients found stronger reactions to the oxidized surfactants; this is mostly a formulation and shelf life issue.

This ingredient does have a comedogenic rating of 3, but this doesn't mean a formula with this ingredient will clog pores. Human testing has proved that any finished product with this ingredient won't automatically make you break out; it really comes down to concentration, formula, and your skin.

The chemistry for this ingredient is reassuring; Malassezia uses long chain fatty acids from its surroundings (C11-24) to grow, and Laureth-23 has no fatty acid for it to grab onto.

Supporting this, closely related alkyl PEG ethers like Ceteth-20 get used in Malassezia lab work as neutral carriers to disperse a separately added fatty acid (not as the food source itself).

A 2012 assessment found this ingredient is used in leave-on products at up to 21%, which is at the very high end for the category; most cosmetic use is far lower and typically in the single digits.

A true allergy to Laureth-4 is rare; similar alcohol ethoxylates tested negative for skin sensitization in undiluted guinea pig studies, and related compounds were non-sensitizing in Magnusson-Kligman maximization tests.

There is one caveat for this whole ingredient family: ethoxylated surfactants slowly oxidize when exposed to air, and it's the oxidation products, not the fresh material, that act as sensitizers. This is mostly a formulation and shelf life issue.

Dr. James Fulton's rabbit ear test from the 1980's scored this ingredient as a 5 on the comedogenic scale. Fulton himself described the rabbit ear as not an ideal model and the tests used undiluted ingredients on rabbit ears, which are more reactive than human facial skin.

Dr. Draelos later used a human assay on finished cosmetic products and found that products built with so-called comedogenic ingredients are not necessarily comedogenic themselves.

This ingredient can be potentially pore clogging if it appears high in the ingredient list of a leave-on product.

The fungal acne picture is actually reassuring: Malassezia uses fatty acids from its surroundings (C11-24). This ingredient has nothing for the Malassezia yeast to use since it is an alcohol and not an acid.

Supporting this, closely related ethoxylated alcohol detergents like Ceteth-20 get used in Malassezia lab work as neutral carriers to disperse a separately added fatty acid (not as the food source itself).

A British study found lauryl glucoside to cause skin sensitivity for some people. We recommend speaking with a professional if you have concerns.

Other names for this ingredient include "Lauryl Polyglucose", "Lauryl glycoside", and "D-Glucopyranoside".

You'll typically see this ingredient used in very small amounts; anything above 0.001% in a leave-on product or 0.01% in a rinse-off has to be named on the label in the EU. The citrus oils that carry it sit around 0.5-1% in a finished formula.

Fresh limonene is a weak allergen; the real issue is that it slowly reacts with air and then breaks down from oxidation to create hydroperoxides (which are strong sensitizers). This is why suppliers are required to keep the peroxide value below 20 mmol.

Positive reactions in people being investigated for eczema vary:

It's worth skipping if you have a known fragrance allergy or a compromised barrier, but the risk is low for most people.

Older or long-opened products are also more likely to bother you than fresh ones due to oxidation.

The EU requires it to be named on the label above 0.001% in leave-on and 0.01% in rinse-off products.

Fresh linalool is a weak sensitizer but air exposure turns some of it into hydroperoxides, which are strong sensitizers. Those oxidation products are the actual allergy concern.

Patch-test clinics see positive reactions to linalool hydroperoxides in about 4% to 12% of dermatitis patients depending on country and test concentration.

Resassuringly, one analytical study found hydroperoxide levels in real fragranced products to be orders of magnitude below what induced sensitization in animal studies with no evidence of oxidation building up during normal storage.

The practical takeaway is that linalool is fine for most people but worth avoiding if you have a confirmed fragrance contact allergy or a badly compromised barrier.

Products stored a long time after opening are also the high-risk scenario since that is when oxidation happens.

The scent of linalool is described as floral, spicy tropical, and citrus-like.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

An expert safety panel reviewed it and found it safe when formulations are made to be non-irritating.

As a pH adjuster, it's typically used well under 1% though regulatory caps go much higher: 5% in nail cuticle removers and 2-4.5% in hair straighteners.

Though there is some concern for irritation from raw or high pH material, a well-balanced formula will be a non-issue for the vast majority of people.

This ingredient also helps improve the spreadability of a product.

This ingredient hasn’t been shown in studies to feed fungal acne yeast.

The Cosmetic Ingredient Review Expert Panel has assessed it and concluded it to be safe as used at these concentrations when formulated to be non-irritating.

Allergy and sensitization risk is low and often when someone reacts to a cleanser it's due to the fragrance or preservatives rather than this ingredient itself.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!