Epionce Intense Defense Serum Versus Medik8 Crystal Retinal - 3
Updated on June 18, 2025
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 9 ingredients in common
Cool Features
They both contain hyaluronic acid, Vitamin C and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, parabens or sulfates
What's Inside
They both contain fragrances and oils
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Epionce Intense Defense Serum 34 ingredients
Medik8 Crystal Retinal 43 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Epionce Intense Defense Serum 34 ingredients
Medik8 Crystal Retinal 43 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningPropanediol
Solvent
Niacinamide
Smoothing
Glycerin
Humectant
Trisiloxane
Skin Conditioning
Tetrahexyldecyl Ascorbate
Antioxidant
PEG-7 Glyceryl Cocoate
Emulsifying
Oryza Sativa Bran Extract
Skin Conditioning
Bidens Pilosa Extract
HumectantBixa Orellana Seed Extract
MaskingButylene Glycol
Humectant
Caprylic/Capric Triglyceride
Masking
Caprylyl Glycol
EmollientCrithmum Maritimum Extract
Skin ConditioningCucumis Melo Fruit Extract
Skin ConditioningDisodium EDTA
Elaeis Guineensis Oil
Emollient
Ethylhexylglycerin
Skin ConditioningGlyceryl Stearate
Emollient
Gossypium Herbaceum Seed Oil
Skin Conditioning
Helianthus Annuus Extract
Emollient
Hexylene Glycol
EmulsifyingHydrogenated Vegetable Oil
Emollient
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingHydroxypropyltrimonium Maltodextrin Crosspolymer
Lentinus Edodes Extract
Skin ConditioningLinum Usitatissimum Seed Oil
Perfuming
PEG-100 Stearate
Phenoxyethanol
Preservative
Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters
Skin Conditioning
Rosmarinus Officinalis Leaf Extract
AntimicrobialSodium Hyaluronate
Humectant
Tocopherol
Antioxidant
Tocopheryl Linoleate/Oleate
Antioxidant
Water, Propanediol, Niacinamide, Glycerin, Trisiloxane, Tetrahexyldecyl Ascorbate, PEG-7 Glyceryl Cocoate, Oryza Sativa Bran Extract, Bidens Pilosa Extract, Bixa Orellana Seed Extract, Butylene Glycol, Caprylic/Capric Triglyceride, Caprylyl Glycol, Crithmum Maritimum Extract, Cucumis Melo Fruit Extract, Disodium EDTA, Elaeis Guineensis Oil, Ethylhexylglycerin, Glyceryl Stearate, Gossypium Herbaceum Seed Oil, Helianthus Annuus Extract, Hexylene Glycol, Hydrogenated Vegetable Oil, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxypropyltrimonium Maltodextrin Crosspolymer, Lentinus Edodes Extract, Linum Usitatissimum Seed Oil, PEG-100 Stearate, Phenoxyethanol, Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters, Rosmarinus Officinalis Leaf Extract, Sodium Hyaluronate, Tocopherol, Tocopheryl Linoleate/Oleate
Water
Skin ConditioningCaprylic/Capric Triglyceride
Masking
Glycerin
Humectant
Isododecane
EmollientCetearyl Olivate
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingCetearyl Alcohol
Emollient
PPG-12/Smdi Copolymer
EmollientSorbitan Olivate
Emulsifying
Tocopheryl Acetate
Antioxidant
Cyclodextrin
AbsorbentSqualane
Emollient
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingHydroxyacetophenone
Antioxidant
3-O-Ethyl Ascorbic Acid
Skin Conditioning
Hydroxypropyl Methylcellulose
Emulsion StabilisingSodium Hyaluronate
Humectant
Phenoxyethanol
Preservative
Tetrahexyldecyl Ascorbate
Antioxidant
Daucus Carota Sativa Seed Oil
Emollient
Retinal
Skin Conditioning
Rubus Chamaemorus Seed Oil
Skin Conditioning
Alumina
Abrasive
Isostearic Acid
Cleansing
Lecithin
Emollient
Polyglyceryl-3 Polyricinoleate
Emulsifying
Lonicera Japonica Flower Extract
Skin ConditioningLonicera Caprifolium Flower Extract
Perfuming
Polyhydroxystearic Acid
Emulsifying
Stearic Acid
Cleansing
Sodium Polyaspartate
HumectantPentylene Glycol
Skin ConditioningCitric Acid
Buffering
Polysorbate 60
Emulsifying
Disodium EDTA
Ethylhexylglycerin
Skin ConditioningBHT
Antioxidant
Sorbitan Isostearate
Emulsifying
Vanilla Planifolia Fruit Extract
Skin Conditioning
Dipteryx Odorata Bean Extract
Masking
Coumarin
Perfuming
CI 14700
Cosmetic ColorantCI 77891
Cosmetic ColorantWater, Caprylic/Capric Triglyceride, Glycerin, Isododecane, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, PPG-12/Smdi Copolymer, Sorbitan Olivate, Tocopheryl Acetate, Cyclodextrin, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyacetophenone, 3-O-Ethyl Ascorbic Acid, Hydroxypropyl Methylcellulose, Sodium Hyaluronate, Phenoxyethanol, Tetrahexyldecyl Ascorbate, Daucus Carota Sativa Seed Oil, Retinal, Rubus Chamaemorus Seed Oil, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Polyhydroxystearic Acid, Stearic Acid, Sodium Polyaspartate, Pentylene Glycol, Citric Acid, Polysorbate 60, Disodium EDTA, Ethylhexylglycerin, BHT, Sorbitan Isostearate, Vanilla Planifolia Fruit Extract, Dipteryx Odorata Bean Extract, Coumarin, CI 14700, CI 77891
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinThis is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateTetrahexyldecyl Ascorbate (THD) is a stable and oil-soluble form of Vitamin C.
THD is special in that it has the ability to travel deeper into skin than traditional ascorbic acid while maintaining the same skin benefits (double win!).
Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.
Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.
Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.
A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).
While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.
THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!
Read more about other types of Vitamin C:
Learn more about Tetrahexyldecyl AscorbateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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When to use
Epionce Intense Defense Serum 34 ingredients
Medik8 Crystal Retinal 43 ingredients
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