Educated Mess Freeze Frame Peptide Serum Concentrate Versus Numbuzin No.9 NAD+ PDRN Glow Boosting Toner
This anti-aging serum is formulated around Resveratrol and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and refine skin texture.
This anti-aging toner is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and brighten dull-looking skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Acetamidoethoxyethanol
Humectant
Propylene Glycol
Humectant
Sodium Acrylates Crosspolymer-2
AbsorbentCyclopentasiloxane
Emollient
Polysorbate 20
Emulsifying
1,2-Hexanediol
Skin Conditioning
Menthyl Lactate
Masking
Resveratrol
Antioxidant
Palmitoyl Pentapeptide-4
Skin Conditioning
Palmitoyl Tetrapeptide-50
Skin Conditioning
Heptapeptide-15 Palmitate
Skin Conditioning
Palmitoyl Hexapeptide-52
Skin Conditioning
Palmitoyl Heptapeptide-18
Skin Conditioning
Diamond Powder
Abrasive
Methylglucoside Phosphate
Skin ConditioningCopper Lysinate/Prolinate
Skin ConditioningSodium Hyaluronate
Humectant
Lactic Acid/Glycolic Acid Copolymer
Skin ConditioningPolyvinyl Alcohol
Xanthan Gum
EmulsifyingDimethicone Crosspolymer
Emulsion Stabilising
Dimethicone
Emollient
Polyacrylate Crosspolymer-6
Emulsion StabilisingHydroxyacetophenone
Antioxidant
Glyceryl Caprylate
EmollientPhenylpropanol
Masking
Phenoxyethanol
Preservative
Caprylyl Glycol
Emollient
Water, Glycerin, Acetamidoethoxyethanol, Propylene Glycol, Sodium Acrylates Crosspolymer-2, Cyclopentasiloxane, Polysorbate 20, 1,2-Hexanediol, Menthyl Lactate, Resveratrol, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-50, Heptapeptide-15 Palmitate, Palmitoyl Hexapeptide-52, Palmitoyl Heptapeptide-18, Diamond Powder, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Sodium Hyaluronate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Xanthan Gum, Dimethicone Crosspolymer, Dimethicone, Polyacrylate Crosspolymer-6, Hydroxyacetophenone, Glyceryl Caprylate, Phenylpropanol, Phenoxyethanol, Caprylyl Glycol
Water
Skin ConditioningMethylpropanediol
SolventNiacinamide
Smoothing
PEG/PPG-17/6 Copolymer
SolventPropanediol
Solvent
1,2-Hexanediol
Skin Conditioning
Tripropylene Glycol
Antioxidant
Glyceryl Glucoside
Humectant
Xylitylglucoside
Humectant
PEG-40 Hydrogenated Castor Oil
Emulsifying
Anhydroxylitol
Humectant
Glycerin
Humectant
Polyglyceryl-10 Laurate
Skin Conditioning
Candida Bombicola/Glucose/Methyl Rapeseedate Ferment
AntimicrobialC20-40 Pareth-10
EmulsifyingTocopheryl Acetate
Antioxidant
Xylitol
Humectant
Cetearyl Alcohol
Emollient
Sodium DNA
Skin Conditioning
Hydrogenated Lecithin
Emulsifying
Glucose
Humectant
Polyacrylate Crosspolymer-6
Emulsion StabilisingEthylhexylglycerin
Skin ConditioningAdenosine
Skin Conditioning
Ceramide NP
Skin Conditioning
Sodium Phytate
Helianthus Annuus Seed Oil
Emollient
Melia Azadirachta Leaf Extract
Skin ConditioningMelia Azadirachta Flower Extract
Skin ConditioningCitric Acid
Buffering
Hydroxyethylcellulose
Emulsion StabilisingSodium Citrate
BufferingPhytosterols
Skin Conditioning
Coccinia Indica Fruit Extract
Skin Conditioning
Aloe Barbadensis Flower Extract
EmollientSolanum Melongena Fruit Extract
Skin ConditioningT-Butyl Alcohol
Perfuming
Ocimum Sanctum Leaf Extract
Skin ConditioningCurcuma Longa Root Extract
Antioxidant
Corallina Officinalis Extract
Skin Conditioning
Cyanocobalamin
Skin ConditioningCaprylic/Capric Triglyceride
Masking
Hydrolyzed Collagen
Emollient
Butylene Glycol
Humectant
Adenosine Triphosphate
Skin ConditioningNicotinamide Adenine Dinucleotide
Skin ConditioningResveratrol
Antioxidant
Pullulan
Sodium Palmitoyl Sarcosinate
CleansingPalmitic Acid
Emollient
C12-14 Alketh-12
EmulsifyingPisum Sativum Peptide
Skin Conditioning
Stearic Acid
Cleansing
Polyglyceryl-6 Laurate
Emulsifying
Caprylyl Glycol
Emollient
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Dextran
Hydrolyzed Elastin
EmollientSoluble Collagen
Humectant
Acetyl Tetrapeptide-3
Skin Protecting
Trifolium Pratense Flower Extract
AstringentDisodium EDTA
Myristic Acid
Cleansing
Acetyl Hexapeptide-8
Humectant
Mannose
HumectantSh-Octapeptide-4
Antioxidant
Sh-Decapeptide-7
Antioxidant
Palmitoyl Pentapeptide-4
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Copper Tripeptide-1
Skin Conditioning
Hexapeptide-9
Skin Conditioning
Nonapeptide-1
Skin Conditioning
Tripeptide-1
Skin Conditioning
Arachidic Acid
Cleansing
Collagen
Moisturising
Elastin
Skin ConditioningGlutathione
Palmitoyl Tetrapeptide-7
Skin Conditioning
Arginine/Lysine Polypeptide
Skin Conditioning
Oligopeptide-29
Antioxidant
Oligopeptide-32
Antiseborrhoeic
Acetyl Tetrapeptide-5
Humectant
Acetyl Tetrapeptide-9
Skin Conditioning
Acetyl Tetrapeptide-2
Skin Conditioning
Acetyl Octapeptide-3
Humectant
Acetyl Hexapeptide-1
Skin Conditioning
Alanine/Histidine/Lysine Polypeptide Copper Hcl
Skin Conditioning
Acetyl Dipeptide-1 Cetyl Ester
Skin Conditioning
Acetyl Sh-Pentapeptide-1
Skin Conditioning
Biotinoyl Tripeptide-1
Dipeptide-4
Skin Conditioning
Hexapeptide-11
Skin Conditioning
Hexapeptide-12
Skin Conditioning
Lauric Acid
Cleansing
Myristoyl Pentapeptide-17
Skin Conditioning
Myristoyl Hexapeptide-16
Skin Conditioning
Myristoyl Pentapeptide-4
Skin Conditioning
Nicotinoyl Tripeptide-1
Antioxidant
Nonapeptide-7
Skin Conditioning
Nicotinoyl Tripeptide-35
Antioxidant
Nicotinoyl Dipeptide-26
Skin Conditioning
Nicotinoyl Dipeptide-23
Skin Conditioning
Octapeptide-2
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Palmitoyl Hexapeptide-12
Skin Conditioning
Pentapeptide-13
Skin Conditioning
Palmitoyl Tetrapeptide-10
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Palmitoyl Tripeptide-29
Skin Conditioning
Palmitoyl Tripeptide-8
Skin Conditioning
Sr-(Oligopeptide-91 Clostridium Botulinum Polypeptide-1)
Skin Conditioning
Tetrapeptide-44
Skin Conditioning
Tetrapeptide-30
Skin Conditioning
Tripeptide-10 Citrulline
Skin Conditioning
Tripeptide-32
Skin Conditioning
Tripeptide-29
Skin Conditioning
Sh-Polypeptide-22
Skin Conditioning
Sh-Oligopeptide-1
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-9
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
Sh-Polypeptide-11
Sh-Polypeptide-3
Skin Conditioning
Sh-Polypeptide-16
Skin Protecting
Sh-Polypeptide-62
Antioxidant
Water, Methylpropanediol, Niacinamide, PEG/PPG-17/6 Copolymer, Propanediol, 1,2-Hexanediol, Tripropylene Glycol, Glyceryl Glucoside, Xylitylglucoside, PEG-40 Hydrogenated Castor Oil, Anhydroxylitol, Glycerin, Polyglyceryl-10 Laurate, Candida Bombicola/Glucose/Methyl Rapeseedate Ferment, C20-40 Pareth-10, Tocopheryl Acetate, Xylitol, Cetearyl Alcohol, Sodium DNA, Hydrogenated Lecithin, Glucose, Polyacrylate Crosspolymer-6, Ethylhexylglycerin, Adenosine, Ceramide NP, Sodium Phytate, Helianthus Annuus Seed Oil, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Citric Acid, Hydroxyethylcellulose, Sodium Citrate, Phytosterols, Coccinia Indica Fruit Extract, Aloe Barbadensis Flower Extract, Solanum Melongena Fruit Extract, T-Butyl Alcohol, Ocimum Sanctum Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Cyanocobalamin, Caprylic/Capric Triglyceride, Hydrolyzed Collagen, Butylene Glycol, Adenosine Triphosphate, Nicotinamide Adenine Dinucleotide, Resveratrol, Pullulan, Sodium Palmitoyl Sarcosinate, Palmitic Acid, C12-14 Alketh-12, Pisum Sativum Peptide, Stearic Acid, Polyglyceryl-6 Laurate, Caprylyl Glycol, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Dextran, Hydrolyzed Elastin, Soluble Collagen, Acetyl Tetrapeptide-3, Trifolium Pratense Flower Extract, Disodium EDTA, Myristic Acid, Acetyl Hexapeptide-8, Mannose, Sh-Octapeptide-4, Sh-Decapeptide-7, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Copper Tripeptide-1, Hexapeptide-9, Nonapeptide-1, Tripeptide-1, Arachidic Acid, Collagen, Elastin, Glutathione, Palmitoyl Tetrapeptide-7, Arginine/Lysine Polypeptide, Oligopeptide-29, Oligopeptide-32, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Acetyl Octapeptide-3, Acetyl Hexapeptide-1, Alanine/Histidine/Lysine Polypeptide Copper Hcl, Acetyl Dipeptide-1 Cetyl Ester, Acetyl Sh-Pentapeptide-1, Biotinoyl Tripeptide-1, Dipeptide-4, Hexapeptide-11, Hexapeptide-12, Lauric Acid, Myristoyl Pentapeptide-17, Myristoyl Hexapeptide-16, Myristoyl Pentapeptide-4, Nicotinoyl Tripeptide-1, Nonapeptide-7, Nicotinoyl Tripeptide-35, Nicotinoyl Dipeptide-26, Nicotinoyl Dipeptide-23, Octapeptide-2, Palmitoyl Tripeptide-5, Palmitoyl Hexapeptide-12, Pentapeptide-13, Palmitoyl Tetrapeptide-10, Palmitoyl Tripeptide-38, Palmitoyl Tripeptide-29, Palmitoyl Tripeptide-8, Sr-(Oligopeptide-91 Clostridium Botulinum Polypeptide-1), Tetrapeptide-44, Tetrapeptide-30, Tripeptide-10 Citrulline, Tripeptide-32, Tripeptide-29, Sh-Polypeptide-22, Sh-Oligopeptide-1, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Oligopeptide-2, Sh-Polypeptide-11, Sh-Polypeptide-3, Sh-Polypeptide-16, Sh-Polypeptide-62
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinYou might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.
As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.
A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.
The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.
The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.
Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.
It is be used to thicken water-based products and create a gel-texture with a velvet feel.
One manufacturer claims this ingredient to have a pH range of 2-8 and to be biodegradable.
This ingredient is also known as Sepimax Zen.
Learn more about Polyacrylate Crosspolymer-6Resveratrol is a well-studied polyphenol antioxidant that has gained attention in skincare for its protective and calming effects on the skin. It’s often considered a gentler option for people who can’t tolerate retinoids.
This antioxidant is best known for its anti-aging benefits. Research suggests resveratrol helps combat visible signs of aging by:
Beyond anti-aging, resveratrol is also valued for its skin-brightening and soothing properties.
Some forms of resveratrol appear to be more effective than others. Resveratrol isobutyrate and resveratrol butyrate are often cited as more stable derivatives.
Research also suggests these two forms have stronger effects on Type I collagen stimulation and inflammation reduction compared to basic resveratrol.
Resveratrol is naturally unstable and can degrade when exposed to light and oxygen. Well-designed products often use stabilized derivatives, airless or opaque packaging, and supporting antioxidants to help maintain effectiveness on skin.
A note on resveratrol as a retinoid alternative:
While resveratrol offers antioxidant protection, inflammation control, and some collagen-supporting benefits, it does not replace retinoids in terms of cell turnover or acne treatment.
However, it can be a useful option for people with retinoid sensitivity or intolerance, or for those looking to support skin health without irritation.
Fun fact: Resveratrol is naturally found in grapes, peanuts, and berries, which is why it’s frequently associated with wine and grape-derived skincare ingredients.
Learn more about ResveratrolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
