DRMTLGY Needle-less Growth Factor Serum
A serum with 42 ingredients, including hyaluronic acid, ceramides, and peptides.
Overview
What it is
Serum with 42 ingredients that contains ceramides, hyaluronic acid and peptides
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
Fun facts
DRMTLGY is from United States.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantButylene Glycol
HumectantPentylene Glycol
Skin ConditioningMaltodextrin
AbsorbentCoco-Caprylate/Caprate
EmollientSaccharide Isomerate
HumectantSodium Hyaluronate
HumectantPalmitoyl Tripeptide-1
Skin ConditioningOligopeptide-3
Skin ConditioningOligopeptide-2
Skin ConditioningOligopeptide-1
Skin ConditioningHexapeptide-11
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningCeramide NP
Skin ConditioningFolic Acid
Skin ConditioningPhytosphingosine
Skin ConditioningCeramide AP
Skin ConditioningCeramide EOP
Skin ConditioningTriheptanoin
Skin ConditioningSwertia Chirata Extract
HumectantPhenoxyethanol
PreservativeAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingC9-12 Alkane
SolventPolyurethane-10
Ethylhexylglycerin
Skin ConditioningSodium Hydroxide
BufferingLecithin
EmollientTrisodium Ethylenediamine Disuccinate
Acetyl Glutamine
Skin Conditioning1,2-Hexanediol
Skin ConditioningTremella Fuciformis Sporocarp Extract
AntioxidantHydrolyzed Hyaluronic Acid
HumectantDecyl Glucoside
CleansingBacillus/Soybean Ferment Extract
Skin ConditioningSodium Lauroyl Lactylate
EmulsifyingCaprylyl Glycol
EmollientCarbomer
Emulsion StabilisingPolysorbate 20
EmulsifyingCholesterol
EmollientXanthan Gum
EmulsifyingWater, Glycerin, Butylene Glycol, Pentylene Glycol, Maltodextrin, Coco-Caprylate/Caprate, Saccharide Isomerate, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Triheptanoin, Swertia Chirata Extract, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C9-12 Alkane, Polyurethane-10, Ethylhexylglycerin, Sodium Hydroxide, Lecithin, Trisodium Ethylenediamine Disuccinate, Acetyl Glutamine, 1,2-Hexanediol, Tremella Fuciformis Sporocarp Extract, Hydrolyzed Hyaluronic Acid, Decyl Glucoside, Bacillus/Soybean Ferment Extract, Sodium Lauroyl Lactylate, Caprylyl Glycol, Carbomer, Polysorbate 20, Cholesterol, Xanthan Gum
Key Ingredients
Benefits
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolMaltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.
In food, Maltodextrin is used to improve the texture and thicken a product. Due to its structure, it can help create a gel texture. As an emulsion stabilizer, it helps keep the ingredients in a product together.
As a polysaccharide, Maltodextrin has moisturizing properties. Polysaccharides are a type of carbohydrate. The top layer of skin uses polysaccharides to retain water, keeping the skin hydrated.
Maltodextrin is water soluble and has a sweet taste.
Learn more about MaltodextrinCoco-Caprylate/Caprate is created from fatty coconut alcohol, caprylic acid, and capric acid.
It is a lightweight emollient. Emollients create a thin barrier on the skin to trap moisture in. This helps keep your skin hydrated and soft.
Once applied, Coco-Caprylate/Caprate is absorbed quickly and leaves a silky feel.
Coco-Caprylate/Caprate may not be fungal acne safe.
Learn more about Coco-Caprylate/CaprateSaccharide Isomerate comes from sugars found in corn. It is a skin hydrator.
The structure of this ingredient can be altered to be more similar to the carbohydrates found in our skin. This ability to mimic our skin gives it hydrating properties.
Specifically, saccharide Isomerate is a humectant. Humectants draw moisture from the air to our skin.
Research shows Saccharide Isomerate to be an effective moisturizer.
Learn more about Saccharide IsomerateSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronatePalmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.
This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.
By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.
You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.
Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Oligopeptide-3 is a peptide.
This synthetic peptide consists of glycine, histidine, and lysine. Peptides have skin conditioning properties.
This name refers to a group of Oligopeptide-1 derivatives, such as the famous Sh-Oligopeptide-1.
This synthetic peptide is known as a signal peptide. Signal peptides tell your skin to create more collagen, elastin and protein.
Hexapeptide-11 is composed of several amino acids, including alanine.
This synthetic peptide is created from lysine, valine, and palmitic acid.
According to the manufacturer, in-vitro studies show tissue growth and collagen synthesis. Another in-vivo study found 60 volunteers saw a significant reduction in wrinkles after 84 days.
Due to its palmitic acid base, this peptide may not be fungal-acne safe.
Learn more about Palmitoyl Tripeptide-5Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).
This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.
Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.
Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.
Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. It’s commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).
Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Ceramide NP is a type of ceramide.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Ceramide AP
Ceramide EOP
Folic acid is a form of Vitamin B9. Our bodies use folic acid for creating new cells and for DNA repair.
Folic acid is an antioxidant, making it an effective skin repair ingredient.
In vivo studies show folic acid to decrease UV-C induced DNA damage on human fibroblasts. This is because folic acid is effective at rejoining breaks in the fibroblast DNA. It is believed folic acid may play a role in reducing UV-B damage as well. While the mechanisms are unknown, it is believed folic acid plays a role in disrupting the DNA damage process.
Studies show using moisturizers rich in folic acid led to increased hydration of the skin. Hydrated skin is essential for collagen and elastin, or for keeping skin plump. One study found a reduction in wrinkles from using folic acid creams.
Foods rich in folic acid include leafy vegetables, beans, peanuts, fresh fruit, and eggs.
Learn more about Folic AcidPhytosphingosine is a phospholipid naturally found in our skin as a building block for ceramides.. It helps moisturize, soothe, and protect skin.
Phytosphingosine contributes to your skin's natural moisturizing factor (NMF). The NMF is responsible for hydration, a strong barrier, and plasticity. Our NMF decreases with age. Increasing NMF leads to more healthy and hydrated skin.
Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.
Fun fact: Phytosphingosine is abundant in plants and fungi.
More ingredients that help boost collagen in skin:
Learn more about PhytosphingosineCeramide AP is a type of Ceramide.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. Having a strong skin barrier leads to more firm and hydrated skin.
They are known for their ability to hold water and thus are a great ingredient for dry skin. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Ceramide NP
Ceramide EOP
Ceramide EOP is a type of Ceramide.
EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.
Ceramides are intercellular lipids naturally found in our skin. They bind dead skin cells together to create a barrier. The ceramides in our skin have the ability to hold water to keep our skin hydrated.
Ceramides are an important building block for our skin barrier. A strong skin barrier helps with:
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Learn more about Ceramide EOPWe don't have a description for Triheptanoin yet.
We don't have a description for Swertia Chirata Extract yet.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products. Due to its properties, it can prevent water and oil ingredients from separating.
C9-12 Alkane is synethically created using alkanes, or paraffins. It is added to products as a solvent. This means its main purpose is to help dissolve ingredients and create even texture.
We don't have a description for Polyurethane-10 yet.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Some other names for this ingredient include soy lecithin and deoiled soy lecithin.
Learn more about LecithinTrisodium Ethylenediamine Disuccinate is used to help stabilize a product.
It is a chelating agent, meaning it helps prevent metal ions from binding to other ingredients. This prevents unwanted reactions in products. Metal ions can come into a product via the water ingredient. They are found in trace amounts and are not known to be harmful.
We don't have a description for Acetyl Glutamine yet.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Tremella Fuciformis is also known as snow mushroom. This ingredient comes from the sporocarp, which is also the fruit body of the fungi.
Snow mushroom has hydrating and antioxidant properties.
According to a manufacturer, the glucuronic acid of this ingredient promotes the presence of hyaluronic acid in the middle layer of skin to keep that layer sufficiently hydrated.
Learn more about Tremella Fuciformis Sporocarp ExtractHydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.
Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.
One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.
Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.
Read more about other common forms of hyaluronic acid:
Learn more about Hydrolyzed Hyaluronic AcidDecyl Glucoside is a glucose-based surfactant and emulsion stabilizer. It is created by reacting glucose with the fatty acids from plants.
Surfactants help clean the skin by trapping oil, sebum, and dirt to be washed away. As an emulsion stabilizer, it stabilizes the ingredients in a product by preventing them from separating.
This ingredient is biodegradable and non-toxic. This ingredient is commonly found in baby shampoos.
Decyl Glucoside is sometimes used to stabilize the UV filter Tinosorb.
Learn more about Decyl GlucosideThis ingredient is created by fermenting soybean extract with the bacteria, bacillus. It has antioxidant and skin conditioning properties.
Sodium Lauroyl Lactylate is the lauric acid sodium salt of lactyl lactate.
Sodium Lauroyl Lactylate is an emulsifier and surfactant.
Emulsifiers help stabilize a product. They do this by preventing ingredients from separating, such as oils and water which do not mix naturally. Surfactants reduce surface tension, making it easier to rinse pollutants off skin.
Due to its relation to lauric acid, it may provide antimicrobial benefits.
Learn more about Sodium Lauroyl LactylateCaprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolCarbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.
Our skin naturally contains cholesterol in the outermost layer. Besides cholesterol, it also contains ceramides and fatty acids. Cholesterol makes up about 1/4 of your skin's outer layer and barrier. Your skin barrier is responsible for keeping allergens and microbes out. Having a healthy skin barrier is also responsible for keeping your skin firm and plump.
Our bodies use cholestrol to create vitamin D, steroid hormones, and more.
Learn more about CholesterolXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumReviews
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Where it's from
DRMTLGY is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated September 11, 2025 • Added by sarahmosley