Dr. Dennis Gross Skincare Alpha Beta® Extra Strength Daily Peel Versus PSA SKIN Goals Multi Acids & Probiotics Perfecting Night Serum
This smoothing treatment is formulated around Glycolic Acid and Salicylic Acid to refine skin texture and brighten dull-looking skin.
This smoothing serum is formulated around Glycolic Acid and Gluconolactone to refine skin texture and brighten dull-looking skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningAlcohol Denat.
AntimicrobialGlycolic Acid
BufferingPotassium Hydroxide
BufferingHamamelis Virginiana Water
AstringentSalicylic Acid
MaskingPolysorbate 20
EmulsifyingLactic Acid
BufferingMandelic Acid
AntimicrobialMalic Acid
BufferingCitric Acid
BufferingSalix Alba Bark Extract
AstringentMenthone Glycerin Acetal
RefreshingCamellia Sinensis Leaf Extract
AntimicrobialAchillea Millefolium Extract
CleansingAnthemis Nobilis Flower Extract
MaskingSoy Isoflavones
Skin ConditioningCopper PCA
HumectantZinc PCA
HumectantLecithin
EmollientDisodium EDTA
Alcohol
AntimicrobialPolysorbate 80
EmulsifyingParfum
MaskingLinalool
PerfumingBenzyl Salicylate
PerfumingBenzoic Acid
MaskingPhenoxyethanol
PreservativeSodium Benzoate
MaskingSodium Bicarbonate
AbrasiveResveratrol
AntioxidantRetinol
Skin ConditioningAscorbic Acid
AntioxidantUbiquinone
AntioxidantAscorbyl Palmitate
AntioxidantPhospholipids
Skin ConditioningRetinyl Palmitate
Skin ConditioningTocopheryl Acetate
AntioxidantRaphanus Sativus Root Extract
AstringentSodium PCA
HumectantBHT
AntioxidantOctoxynol-9
EmulsifyingSimethicone
EmollientTetrasodium EDTA
Water, Alcohol Denat., Glycolic Acid, Potassium Hydroxide, Hamamelis Virginiana Water, Salicylic Acid, Polysorbate 20, Lactic Acid, Mandelic Acid, Malic Acid, Citric Acid, Salix Alba Bark Extract, Menthone Glycerin Acetal, Camellia Sinensis Leaf Extract, Achillea Millefolium Extract, Anthemis Nobilis Flower Extract, Soy Isoflavones, Copper PCA, Zinc PCA, Lecithin, Disodium EDTA, Alcohol, Polysorbate 80, Parfum, Linalool, Benzyl Salicylate, Benzoic Acid, Phenoxyethanol, Sodium Benzoate, Sodium Bicarbonate, Resveratrol, Retinol, Ascorbic Acid, Ubiquinone, Ascorbyl Palmitate, Phospholipids, Retinyl Palmitate, Tocopheryl Acetate, Raphanus Sativus Root Extract, Sodium PCA, BHT, Octoxynol-9, Simethicone, Tetrasodium EDTA
Water
Skin ConditioningGlycerin
HumectantGlycolic Acid
BufferingGluconolactone
Skin ConditioningPropanediol
SolventCalophyllum Inophyllum Seed Oil
AntimicrobialSodium Hydroxide
BufferingTocopheryl Acetate
AntioxidantPyruvic Acid
MaskingLactobacillus Ferment
Skin ConditioningBisabolol
AntioxidantLeuconostoc/Radish Root Ferment Filtrate
AntimicrobialRosa Canina Seed Oil
EmollientLactic Acid
BufferingSalicylic Acid
MaskingNiacinamide
SmoothingSodium PCA
HumectantGlycyrrhiza Glabra Root Extract
BleachingButyrospermum Parkii Butter
Skin ConditioningCamellia Sinensis Leaf Extract
AntimicrobialCentella Asiatica Leaf Extract
Skin ConditioningHyaluronic Acid
HumectantSodium Hyaluronate Crosspolymer-3
HumectantPentapeptide-59
Skin ConditioningTetrahydrodiferuloylmethane
AntioxidantTetrahydrodemethoxydiferuloylmethane
AntioxidantTetrahydrobisdemethoxydiferuloylmethane
AntioxidantHydroxyethylcellulose
Emulsion StabilisingSclerotium Gum
Emulsion StabilisingMaltodextrin
AbsorbentSodium Gluconate
Skin ConditioningHydrogenated Lecithin
EmulsifyingDimethyl Sulfone
SolventEthylhexylglycerin
Skin ConditioningPotassium Sorbate
PreservativePhenethyl Alcohol
MaskingPhenoxyethanol
PreservativeWater, Glycerin, Glycolic Acid, Gluconolactone, Propanediol, Calophyllum Inophyllum Seed Oil, Sodium Hydroxide, Tocopheryl Acetate, Pyruvic Acid, Lactobacillus Ferment, Bisabolol, Leuconostoc/Radish Root Ferment Filtrate, Rosa Canina Seed Oil, Lactic Acid, Salicylic Acid, Niacinamide, Sodium PCA, Glycyrrhiza Glabra Root Extract, Butyrospermum Parkii Butter, Camellia Sinensis Leaf Extract, Centella Asiatica Leaf Extract, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer-3, Pentapeptide-59, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Hydroxyethylcellulose, Sclerotium Gum, Maltodextrin, Sodium Gluconate, Hydrogenated Lecithin, Dimethyl Sulfone, Ethylhexylglycerin, Potassium Sorbate, Phenethyl Alcohol, Phenoxyethanol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Camellia Sinensis Leaf Extract (tea extract) is one of the most well-researched plant extracts in skincare with an impressive resume.
Black tea, green tea, and oolong tea are all harvested from the Camellia Sinensis plant.
Studies show green tea extract and its catechins (like epigallocatechin gallate (EGCG)) help your skin cells product energy more efficiently and reducing the number of free-radicals that can damage your skin from the inside.
In lab-grown skin models, this translated to younger, healthier, and stronger skin.
There's also good sun protection data; researchers saw less DNA damage and redness on human skin when green tea was applied before UVB exposure. And the more they applied, the better the protection.
Needless to say, this ingredient shouldn't replace your sunscreen. But it is a great supportive ingredient that you can already find in many sunscreens and antioxidant serums.
A 2009 study found a 2% green tea lotion was effective for mild-to-moderate acne thanks to its anti-inflammatory and mild antimicrobial activity.
The quality of the extract matters a lot here:
Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing. We recommend reaching out to the brand if you have questions about the quality or source of their ingredients.
Human Repeated Insult Patch Testing showed no irritation or sensitization at use concentrations (0.86% in leave-on products and up to 30% as leaf water).
Learn more about Camellia Sinensis Leaf ExtractGlycolic Acid is arguably the most famous alpha hydroxy acid (AHA) with tons of research backing its benefits.
It is found naturally in sugar cane but the form used in skincare is usually synthetic for purity and stability.
Glycolic acid removes the top layer of dead skin cells to allow newer and fresher ones to emerge.
AHAs work by breaking down the structural “glue” that holds old skin cells in place. When that buildup is gone, your skin can renew itself more efficiently.
Research also shows glycolic acid stimulates collagen production, helping to firm and thicken the skin over time. This is one of its biggest advantages over other AHAs.
Overall, glycolic acid helps with:
Fun fact: Glycolic acid boosts skin hydration by helping it produce molecules that increase hyaluronic acid naturally.
To work best, glycolic acid products should have a pH between 3-4 (that’s where exfoliation is most effective but still gentle on skin).
The pH and concentration of a product are key to its effectiveness:
It is normal to feel a slight stinging sensation when using glycolic acid. This usually fades as your skin adjusts.
Because glycolic acid has the smallest molecular size in the AHA family, it can penetrate deeper, which enhances its effectiveness but also makes it more likely to irritate sensitive skin.
If your skin is very sensitive or prone to rosacea, glycolic acid may be too strong; in that case, try milder options like lactic acid or a PHA instead.
Recent studies suggest glycolic acid might even help protect against UV damage. But don’t skip sunscreen! Freshly exfoliated skin is more sensitive to the sun.
Glycolic acid is a skincare superstar. It smooths, brightens, hydrates, and firms the skin. Unless you’re highly sensitive, it’s well worth adding to your routine.
Read more about some other popular AHA's here:
Learn more about Glycolic AcidLactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolSalicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.
Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.
Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.
Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.
It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.
While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.
If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.
Learn more about Salicylic AcidSodium PCA (the salt of PCA) is one of the most well-established humectants in skincare.
Why is it so special? Your skin already makes it naturally; it's a natural component of your skin's Natural Moisturizing Factor (NMF), or the mix of water-binding compounds inside your skin cells that keeps things soft and hydrated.
As a cosmetic ingredient, it grabs water and holds it in the upper layers of skin to smooth roughness and ease dehydration.
There's some clinical support for the NMF approach with a study showing that a cream built to mimic the skin's NMF significantly boosted hydration.
Safety-wise, this ingredient non-irritating, non-comedogenic, and non-phototoxic in testing, with minimal skin absorption.
It also works really well with other hydrators like glycerin or hyaluronic acid, and typical usage is somewhere between 0.2-4%.
Learn more about Sodium PCATocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water