House of Balance Eye Slow Oil Roller

This combination is not really found in any other plant oil and is the reason this is one of the most stable botanical oils available.

Some studies show it to be more stable than jojoba oil, helps a product resist going rancid, and can help extend the shelf life of a formula.

It also naturally contains vitamin E and phytosterols that give it a mild antioxidant benefit.

This ingredient is typically used from around 1% to fairly high levels since it's gentle; it's well-tolerated and low on the irritation scale.

Squalene is also naturally present in olive oil and exhibits moisturizing and antioxidant properties.

The polyphenols in olive oil also show anti-aging promise; one clinical study found a measurable improvement in skin appearance after 30 days of topical serum use.

Just be aware that applying olive oil directly to skin can weaken the barrier and cause redness. One study with volunteers found even people without sensitive skin experienced a significant reduction in stratum corneum integrity and induced mild erythema.

It's best to use this ingredient as part of a carefully crafted formula (instead of putting it on skin directly from the bottle).

Because it has a 2-3 on the comedogenic scale, it is a moderate risk for acne-prone skin. However, the overall formulation of a product matters more than a few ingredients with comedogenic ratings.

This ingredient may not be fungal acne safe because of the oleic and palmitic acid content. These fall within the C11-24 fatty acid range that the Malassezia yeast can metabolize to grow.

Overall, olive oil is a well-studied and nourishing skincare ingredient.

One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day.

For most people, this is a well-tolerated and lightweight ingredient.

This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

This ingredient contains a group of yellow pigments called curcuminoids (mostly curcumin) that give it genuine antioxidant and anti-inflammatory activity in skin.

Reviews of topical clinical studies have found turmeric/curcumin to be generally well-tolerated and useful across conditions like eczema and mild inflammation.

One thing working in its favor is that curcumin barely penetrates; in lab skin-permeation testing, the curcuminoids mostly stayed in the outermost layer of skin. This is a good thing because its soothing and antioxidant activity is a surface-level job anyway.

At this time, industry data shows there's no single "correct" cosmetic percentage. It's used across a wide range depending on the product and varies from tiny fractions of a percent up to a few percent.

Allergy-wise, curcumin is a documented (but uncommon) contact allergen. It can also cross react with related plants, so anyone with a turmeric/ginger/cinnamon allergy or reactive skin should patch test first.

The flowers of this tree are lilac colored.

Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

A 2017 study found neem oil was effective at treating wrinkles and dry skin in mice. The study also found higher levels of elastin and procollagen.

There's also some interesting research on its potential to support hair growth by promoting the growth phase of the hair cycle.

Those with an allergy to plants in the daisy family may want to patch test this ingredient. This ingredient is generally well-tolerated otherwise.

Extracted polysaccharides, galactose and xylose, in red algae showed antioxidant activity. Antioxidants help with anti-aging by neutralizing free-radical molecules. Free-radical molecules may damage your skin cells and DNA. Galactose is also a PHA.

Corallina Officinalis is structurally similar to coral due to its high calcium content.

Notably, this ingredient is oxidatively stable for an oil and resists going rancid as fast as other oils.

A small, in vivo study on 32 participants found a cream with this ingredient increased skin hydration with no reported skin irritation. It also found the tocopherol content gave it some antioxidant activity as well.

One thing to flag for fungal acne:
Because this oil is so high in oleic acid, Malassezia can use it as a food source and this ingredient may not be fungal acne safe.

For everyone else, this ingredient is well-tolerated and nourishing with a good safety track record.

While Holy Basil has many claims to help fight acne, more research is needed.

One thing to note is the presence of tannins; tannins are naturally found in nature. However, this compound may be skin-sensitizing.

The extract itself has demonstrated antioxidant, soothing, and potential anti-allergy properties.

Most of this research is done in vitro and dedicated clinical studies on topical application are still limited.

Lab studies have shown that eggplant extracts can lower oxidative stress and protect skin cell membranes from damage. A 2025 study found that specific compounds in eggplant (particularly a phenolamide called N-Trans-Feruloylputrescine) may support skin health by neutralizing 2-nonenal, a byproduct linked to aging skin.

Overall, this is a gentle, well-tolerated ingredient that adds a little extra antioxidant support to your routine.

Those with nighshade vegetable allergies (tomatoes, peppers, potatoes) should patch test as eggplant is part of the same family.

Unsaponifiables have high antioxidant potential due to the tocopherols, carotenoids, and phenolic acids that help protect skin from free radical damage. On the other hand, linoleic acid supports the skin's barrier by replenishing ceramides and reducing transepidermal water loss.

A manufacturer-sponsored clinical study found that a cream with 2% of this ingredient increased skin moisturization by 48.6% after 1 hour and 34.2% after 24 hours.

Using this cream twice-daily for 4 weeks showed meaningful improvement in dryness, roughness, and desquamation (the shedding of dead skin cells).

Keep in mind this is a small, industry-funded study so it'd be great to see independent replication. However, the mechanism is consistent with well-establish linoleic and phytosterol research.

While this ingredient is generally considered safe, those with an Asteraceae/Compositae plant allergy should patch test this ingredient.

Fungal acne: this ingredient is not considered safe for fungal acne because the Malassezia yeast preferentially metabolizes in the C11-24 range. Linoleic acid falls into this range at C18.

Unlike other plant oils, jojoba wax doesn't easily penetrate skin. It mostly works in the uppermost layers as an emollient. This just means it forms a light barrier on the skin to help retain moisture.

Formulations with jojoba esters up to 90% reduced transepidermal water loss (TEWL) and increased barrier recovery by 81% (outperforming bisabolol at 47%).

Besides barrier support, the science also suggests jojoba to have anti-inflammatory effects and potential applications for skin infections, aging, and wound healing.

Fun fact: Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.

Fungal acne: The Malassezia yeast is known to metabolize fatty acids in the C11-24 range and jojoba's dominant fatty acid components fall into this range. This ingredient may not be fungal acne safe.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Hydrogenated Polyisobutene is often used as a mineral oil replacement.

The gamma-linoleic acid (GLA) is the headliner here; it's relatively rare in plant oils and acts as a precursor for anti-inflammatory signaling molecules in the skin.

There's a mixed body of clinical research with this ingredient as well, mostly on eczema/atopic dermatitis skin.

Some controlled trials showed improvement in inflammation, dryness, scaling, and overall severity. Other studies and large meta-analysis failed to show a significant effect; the honest takeaway here is "promising but inconsistent" rather than "miracle oil".

On the safety front, this ingredient is found to be safe as used in cosmetics and even has a history of safe food use.

Since this oil is contains oleic acid and palmitic acid, it may not be fungal acne safe. The Malassezia yeast feeds on fatty acids with carbon chain lengths between C11-C24. Oleic Acid sits at C18 and Palmitic acid sits at C16.

In vitro studies have shown that oleic acid and palmitic acid are some of the fatty acids that induce rapid Malassezia growth in lab settings.

It's a well-vetted ingredient for safety and does not penetrate into skin due to its large molecule size.

Because it's a long-chain fatty acid ester, this ingredient may not be fungal acne or Malassezia safe.

It does have a penetration-enhancing reputation that is a bit more nuanced than marketing suggests; a cell study on human skin found that 10% DMI didn't significantly boost the permeation of Hydroquinone, Salicylic Acid, or Octadecenedioic Acid compared to controls (though it did improve their solubility in the formula itself).

Typical usage concentrations usually range from 1-10% depending on the formula's needs; this ingredient is also well tolerated at these levels.

Lab work on purified acidic sophorolipids suggests they can be less cytotoxic/irritating in skin-model testing than a common harsh surfactant (SLES) at the tested conditions.

By the way, the final cosmetic ingredient does not contain live yeast. It’s a processed fermentation-derived ingredient.

Your body uses linoleic acid to build ceramides and prostaglandins. Ceramides keep your skin's barrier hydrated and strong while prosaglandins help control inflammation and healing.

Needless to say, linoleic acid is crucial for having a strong skin barrier.

One study found applying linoleic acid rich sunflower oil to be more effective at repairing the skin barrier than olive oil.

This ingredient can also help treat acne by softening sebum to prevent clogged pores. Another study found using 2.5% linoleic acid gel for 4 weeks showed a 25% reduction in small comedones.

Studies show it can also help lighten hyperpigmentation or sun spots by disrupting the melanin production process. It also helps your skin shed melanin pigment from your skin caused by UV exposure.

Due to its role in the production of the fatty acid prostaglandin, linoleic acid can also help reduce inflammation and support wound healing.

Fun fact: Linoleic acid is an essential fatty acid. This means our bodies cannot create it on its own and we need to get it through foods such as nuts and vegetable oils.

Just know this ingredient is not always fungal-acne safe because it is a long-chain fatty acid (with 18 carbon atoms) that directly feeds the Malassezia yeast responsible for fungal acne.

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Research shows:

A 1998 study did find that applying oleic acid at higher concentrations may cause irritation and disrupt the skin barrier. Modern formulations typically use low levels that is well-tolerated.

The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Oleic Acid, at C18, falls right into that sweet spot.

In vitro studies have shown that Oleic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.

In practice, this means it does the classic retinoid jobs in a formula:

The best part is that it can do all this with noticeably less redness, flaking, and stinging than traditional retinoids.

That gentle reputation is backed by lab work as well; a 2018 study on skin models found that HPR triggered higher retinoid-gene activity than retinol, retinal, or retinyl propionate at the same concentrations while being less irritating to cells.

It also boosted procollagen production to levels similar to retinoic acid itself.

A 2023 study showed HPR works synergistically with retinyl propionate to switch on collagen-building pathways and a 2025 clinical serum study in women with mild photoaging saw improvements in wrinkles and elasticity (though that formula also contained retinol, peptides, and Silybin).

One naming quirk worth mentioning:

You'll likely see this ingredient sold under the trade name "Granactive Retinoid", which is actually only 10% HPR blended with 90% Dimethyl Isosorbide solvent. This means a 5% Granactive Retinoid really only means about 0.5% HPR.

Finished products typically land somewhere between 0.05-1% and it's happiest formulated at a mildly acidic to neutral pH (~5.5-6.5).

Another perk is that this is one of the more light- and temperature-stable retinoids which is a nice bonus for shelf life.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Interestingly, topically applied Palmitic Acid can be elongated into longer chain fatty acids and ceramides. A 2019 study found low levels of Palmitic Acid lead to slower development of cells, suggesting it plays a role in keeping your skin's renewal process on track.

The CIR (Cosmetic Ingredient Review) panel determined it safe as used in cosmetics at concentrations up to 13%. It is non-irritating and non-sensitizing in clinical studies.

The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Palmitic Acid, at C16, falls right into that sweet spot.

In vitro studies have shown that Palmitic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.

It's worth noting that what feeds yeast in a lab doesn't necessarily feed it on your face since formulation and your skin's chemistry play a bigger role.

Wakame prefers cold and temperate oceans. It is used in Japanese and Korean cuisine (yummy!).

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.

One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.

While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.

The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption.

Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.

Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

ALA is a great skin hydrator because it has the ability to restore lipids in our stratum corneum, or outermost layer of our skin; it also helps prevent transepidermal water loss.

This ingredient also helps soothe irritated skin by downregulating inflammation.

Chia seed oil is one of the highest natural sources of ALA. Research shows topical chia seed oil significantly improves skin hydration, reduces itch, and strengthens the barrier in both healthy and extremely dry skin.

Additionally, in-vivo and in-vitro studies show ALA exhibits antioxidant properties, reduces UV-induced inflammation, and supports wound healing.

Early research showed a fatty-acid deficiency in animals leads to abnormal skin barrier function. It is believed a deficiency in linolenic acid may be linked to skin disorders like eczema.

Fun fact: This ingredient is considered an essential fatty acid for humans. This means our bodies cannot naturally produce it and we must get it from food. Some foods rich in linolenic acid include walnuts, fish oils, soy, and canola.

Studies show this ingredient to be safe for cosmetics. When it is undiluted, it can cause skin irritation. (It is always diluted in skincare and makeup). This ingredient is water-soluble.

Propylene Carbonate is created from propylene glycol and carbonic acid.

Beyond hydration, Biosaccharide Gum-1 gives formulas a silky, non-sticky feel.

This ingredient is gentle, versatile, and suitable for all skin types.

Fun fact: Similar sugars can be found naturally in fruits like apples and pears.

A 2023 review noted that probiotic fermentation ingredients like this one can enhance antioxidant capacity, reduce UV-induced oxidative damage, and support barrier function.

One clinical study from the same year showed a Lactobacillus ferment lysate significantly reduced transepidermal water loss and improved skin hydration.

Another review highlighted that topical Lactobacillus-based preparations can improve ceramide levels in the stratum corneum, support barrier integrity, and even help reduce S. aureus colonization in atopic dermatitis.

Why is this so cool?

Basically, your skin's outer layer works as a brick wall; skin cells are bricks and ceramides are the mortar holding it together. Moisture escapes, irritants get in, and your skin gets dry and reactive when ceramide levels drop. On top of that, "bad" skin bacteria S. aureus loves to move in when your barrier is weak to make inflammation and irritation worse.

So Lactobacillus ferment is basically patching the wall and evicting the troublemaker when it boosts ceramide production and help keep S. aureus in check.

On top of all this, it also acts as a mild antimicrobial preservative booster.

Just so you know, most studies focus on specific strains or the lysate form rather than this generic "Lactobacillus Ferment", so results can vary.

Though it's a promising ingredient, it doesn't have decades of robust clinical data behind it just yet.

Lactobacillus Ferment is generally considered safe for fungal-acne prone skin. The key thing to understand is that it comes from bacteria, not yeast or fungus.

Yeast-derived ferments (like galactomyces) have been shown to activate a protein that's linked to Malassezia-related skin issues whereas lactobacillus doesn't have that problem.

Its byproducts also don't contain the types of fatty acids (C11-24 chain lengths) that Malassezia feeds on.

Zhi Mu root is rich in sarsasapogenin. This compound has anti-inflammatory and soothing properties.

It is commonly used in East Asian medicine.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.

In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.

Human clinical data is promising, but modest:

A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.

A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.

You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.

Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.