Acnes Deep Wash Cleanser

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Research indicates that this ingredient posts a low risk of irritation and sensitization.

Since myristic acid is a C14 fatty acid, it falls within the range that Malassezia can metabolize, and therefore not fungal acne safe.

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Using high concentrations of Potassium Hydroxide have shown to irritate the skin.

Lab studies have found that lauric acid is surprisingly good at killing acne-causing bacteria. However, these tests were done on bacteria in a petri dish and not on real skin, so we can't say for certain it works the same in a formulation on a real face.

The comedogenic rating of 4 comes from the 1972 rabbit ear model using undiluted ingredients. Comedogenicity is highly individual and one comedogenic ingredient cannot predict how a formula will behave on skin.

This ingredient is not fungal acne safe and research has confirmed Malassezia can use it as a food source.

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Japanese manufacturers will sometimes call this ingredient PEG 1540.

It has become less popular in recent formulations due to potential irritation in sensitive skin types and concerns about trace amounts of diethanolamine (DEA), which can potentially form nitrosamines.

While still considered safe at regulated concentrations, many manufacturers now opt for gentler alternatives like cocamidopropyl betaine or other surfactants that offer similar benefits with fewer potential drawbacks.

Being created from coconut oil means Cocamidopropyl Betaine is hydrating for the skin.

While Cocamidopropyl Betaine was believed to be an allergen, a study from 2012 disproved this. It found two compounds in unpure Cocamidopropyl Betaine to be the irritants: aminoamide and 3-dimethylaminopropylamine. High-grade and pure Cocamidopropyl Betaine did not induce allergic reactions during this study.

Is it bad for your skin?

The answer comes down to concentration. Patch and wash studies have found highly concentrated alcohol-based hand rubs (60-100%) cause less barrier disruption than washing with a basic detergent like SLS. The only measurable effect in these studies was a temporary dip in skin hydration.

Concentrations below 12-15% in leave-on cosmetics is generally well-tolerated. Concentrations above start to see increased transepidermal water loss (TEWL) and reduced hydration.

In concentrations about 58%, it creates temporary channels in your skin's lipid layers to become more permeable and allow other ingredients to slip through easily.

This ingredient can be up to 80% of the formula in alcohol-based perfumes.

Overall, this ingredient is probably harmless if found lower down an ingredients list but worth side-eyeing if it's high up (especially if your barrier is already struggling).

Alcohol can worsen dry skin, eczema, and oily skin, especially at higher concentrations. This is because it can increase transepidermal water loss and decrease hydration to disrupt the skin barrier.

According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.

True allergic contact dermatitis to ethanol is uncommon, but be sure to patch test if you have dry or sensitive skin.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.

Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.

It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.

While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.

If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.

You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.

You might see this ingredient used in scrubs as a primary exfoliating ingredient.

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

As an antioxidant, it helps fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Thus, antioxidants may reduce the signs of aging.

This ingredient is oil-soluble.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

The dominant fatty acid is lauric acid (44-54%) and then myristic acid (13-19%). There are also small amounts of caprylic, capric, palmitic, oleic, and linoleic acids.

Human testing from CIR has shown no indication this ingredient to be a primary irritant, sensitizer, or phototoxic compound. It's COSMOS-approved for natural and organic products.

Due to the fatty acid content, this ingredient may not be fungal acne safe. Research has confirmed Malassezia can use lauric acid as a food source.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Fun fact: Purslane is a succulent with an extensive habitat. It is used in traditional Korean medicine to treat irritated skin.

Nowadays, purslane is becoming a superfood due to its highly nutritious content.

Synthetically created CI 77492 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Most kaolin is a white color, but may be pink/orange/red depending on where it comes from.

The name 'kaolin' comes from a Chinese village named 'Gaoling'. Kaolin clay comes from rocks rich in kaolinite. Kaolinite, the mineral, has a silicate layered structure. Kaolinite is formed from chemical weathering of aluminum siilicate minerals.

Besides skincare, kaolin is commonly used to make glossy paper, in ceramics, toothpaste, and as medicine to soothe stomach issues.

As a polysaccharide, Maltodextrin has moisturizing properties. Polysaccharides are a type of carbohydrate. The top layer of skin uses polysaccharides to retain water, keeping the skin hydrated.

Maltodextrin is water soluble and has a sweet taste.

You'll usually find this in concentrations between 0.2-5%.

Studies show Madecassic Acid helps soothe the skin due to its ability to block inflammation pathways.

As an antioxidant, asiatic acid helps protect our skin against damaging environmental factors.

Studies show Laminaria Japonica has antioxidant compounds. Antioxidants may help with anti-aging. Kelp also contains magnesium and zinc, making it great for calming inflammation and redness.

Witch Hazel has astringent, anti-inflammatory, antioxidant, and antibacterial properties.

The tannin content of witch hazel constrict the appearance of pores by drying out proteins. Witch hazel water gets anti-inflammatory and antibacterial properties from its catechin and gallic acid content.

However, witch hazel may be skin-sensitizing due to the tannin and fragrance compounds.

North American Indigenous groups have used witch hazel to help treat inflammation for centuries.

It also has conditioning properties that mostly sits on the surface of skin as an emollient. Some lab research has explored it in anti-aging formulas, but the results were modest.

Recent clinical work on a proprietary Astragalus + Centella saponin system showed improvement in skin aging and quality.

Overall, this ingredient is a great supportive ingredient with low irritation risk.

This ingredient soothes skin inflammation by inhibiting inhibiting a part of the inflammation process.

Marigolds have been used in traditional medicine throughout Asia and Europe.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).