Skintific 5x Ceramide Serum Sunscreen SPF 50+ Versus La Roche-Posay Anthelios UVMune 400 Hydrating Cream SPF 50+ Unscented
This chemical sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
This chemical sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningPentylene Glycol
Skin ConditioningCoco-Caprylate/Caprate
EmollientEthylhexyl Methoxycinnamate
UV AbsorberGlycerin
HumectantDimethicone
EmollientButylene Glycol
HumectantCaprylyl Methicone
Skin ConditioningC12-15 Alkyl Benzoate
AntimicrobialC14-22 Alcohols
Emulsion StabilisingCeramide EOP
Skin ConditioningCeramide Ns
Skin ConditioningCeramide Ng
Skin ConditioningCeramide NP
Skin ConditioningCeramide As
Skin ConditioningCeramide AP
Skin ConditioningHyaluronic Acid
HumectantCentella Asiatica Extract
CleansingBis-Ethylhexyloxyphenol Methoxyphenyl Triazine
UV AbsorberGlycereth-26
HumectantTriacontanyl Pvp
HumectantMethylene Bis-Benzotriazolyl Tetramethylbutylphenol
UV FilterEthylhexyl Triazone
UV AbsorberDecyl Glucoside
CleansingSorbitan Caprylate
EmulsifyingSteareth-21
CleansingTocopheryl Acetate
AntioxidantC12-20 Alkyl Glucoside
EmulsifyingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Ectoin
Skin ConditioningAluminum Starch Octenylsuccinate
AbsorbentAllantoin
Skin ConditioningBisabolol
AntioxidantBifida Ferment Filtrate
Skin ConditioningDisodium EDTA
ChelatingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingPortulaca Oleracea Extract
Skin ConditioningSodium Hyaluronate
HumectantMaris Aqua
HumectantXanthan Gum
Emulsifying1,2-Hexanediol
Skin ConditioningHydroxyacetophenone
AntioxidantPhormidium Persicinum Extract
AntioxidantHydrolyzed Rhodophyceae Extract
Pancratium Maritimum Extract
BleachingWater, Pentylene Glycol, Coco-Caprylate/Caprate, Ethylhexyl Methoxycinnamate, Glycerin, Dimethicone, Butylene Glycol, Caprylyl Methicone, C12-15 Alkyl Benzoate, C14-22 Alcohols, Ceramide EOP, Ceramide Ns, Ceramide Ng, Ceramide NP, Ceramide As, Ceramide AP, Hyaluronic Acid, Centella Asiatica Extract, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Glycereth-26, Triacontanyl Pvp, Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, Ethylhexyl Triazone, Decyl Glucoside, Sorbitan Caprylate, Steareth-21, Tocopheryl Acetate, C12-20 Alkyl Glucoside, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Ectoin, Aluminum Starch Octenylsuccinate, Allantoin, Bisabolol, Bifida Ferment Filtrate, Disodium EDTA, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Portulaca Oleracea Extract, Sodium Hyaluronate, Maris Aqua, Xanthan Gum, 1,2-Hexanediol, Hydroxyacetophenone, Phormidium Persicinum Extract, Hydrolyzed Rhodophyceae Extract, Pancratium Maritimum Extract
Water
Skin ConditioningDiisopropyl Sebacate
EmollientAlcohol Denat.
AntimicrobialEthylhexyl Salicylate
UV AbsorberEthylhexyl Triazone
UV AbsorberBis-Ethylhexyloxyphenol Methoxyphenyl Triazine
UV AbsorberDiisopropyl Adipate
EmollientPEG-8
HumectantDipropylene Glycol
HumectantC12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer
StabilisingGlycerin
HumectantDrometrizole Trisiloxane
UV AbsorberAluminum Starch Octenylsuccinate
AbsorbentButyl Methoxydibenzoylmethane
UV AbsorberMethoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate
StabilisingSilica
AbrasiveTocopherol
AntioxidantDiethylamino Hydroxybenzoyl Hexyl Benzoate
UV FilterAcrylates Copolymer
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCaprylyl Glycol
EmollientHydroxyacetophenone
AntioxidantPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantSodium Polyacrylate
AbsorbentTerephthalylidene Dicamphor Sulfonic Acid
UV AbsorberTriethanolamine
BufferingTrisodium Ethylenediamine Disuccinate
ChelatingWater, Diisopropyl Sebacate, Alcohol Denat., Ethylhexyl Salicylate, Ethylhexyl Triazone, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Diisopropyl Adipate, PEG-8, Dipropylene Glycol, C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer, Glycerin, Drometrizole Trisiloxane, Aluminum Starch Octenylsuccinate, Butyl Methoxydibenzoylmethane, Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate, Silica, Tocopherol, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Acrylates Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Hydroxyacetophenone, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Polyacrylate, Terephthalylidene Dicamphor Sulfonic Acid, Triethanolamine, Trisodium Ethylenediamine Disuccinate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerAluminum Starch Octenylsuccinate is a synthetic powder used as an absorbent, thickener, and anti-caking agent.
As an absorbent, it is great at mattifying skin by soaking up the oil. This is why you'll find it in a range of products from makeup to moisturizers.
This ingredient is considered a modified starch. Starch can also be found naturally in plants.
One study from 1991 found that 5% of this ingredient enhanced titanium dioxide SPF by as much as 40%. The study found 1% titanium dioxide had a 5.6 SPF and adding 5% of aluminum starch octenylsuccinate boosted it to an SPF of 8.1
Although “aluminum” in an ingredient name can raise red flags for some consumers, the form and usage context matter significantly. For typical topical applications, there is no substantial evidence of health risks - such as cancer, neurotoxicity, or systemic “aluminum overload.”
Learn more about Aluminum Starch OctenylsuccinateThis ingredient is better known as bemotrizinol or Tinosorb S and is one of the best broad-spectrum UV filters in modern sunscreen.
It works by absorbing UV light across a whole range (280-400 nm) with peaks around 310 nm (UVB) and 340-345 nm (UVA). This means it covers UVB plus the deeper UVA wavelengths that drive photoaging and pigmentation.
Another pro?
It's exceptionally photostable, barely degrades in sunlight, and acts as a "bodyguard" for less stable filters.
That's why you'll see it paired with avobenzone or octinoxate; this team up ensures they keep working through sun exposure.
Safety reviews have been reassuring across the board. This ingredient shows low absorption through the skin, rarely irritates, and lab studies found it doesn't act like a hormone in the body (a concern that's been raised about some older sunscreen filters).
On maximum concentrations:
In 2026, the US F.D.A finally added it as an OTC sunscreen ingredient at concentrations up to 6% for adults / children 6 months and older
Learn more about Bis-Ethylhexyloxyphenol Methoxyphenyl TriazineEthylhexyl Triazone (aka Octyl Triazone) is an oil-soluble organic UVB filter. It has peak absorption around 314 nm, right in the middle of the UVB range.
This ingredient is described as one of the most effective UVB filters available and small concentrations are enough to deliver a high SPF thanks to its strong UV absorbing power.
Formulators love it for its stability; its ability to filter UV stays practically unchanged even under intense radiation and it can also help boost the photostability of less stable filters like avobenzone.
It's also a great pick for water resistant products because it's insoluble in water and has a good affinity for keratin.
Because it's a big, heavy molecule, the European Scientific Committee has found to to have very low dermal penetration and negative results for allergenicity.
In vitro testing also showed a low absorption rate and clean results on irritation.
Typical use levels are 1-5% with 5% being the maximum in the EU, Japan, and other markets that allow it. However, this ingredient is not approved yet in the US or Canada.
Learn more about Ethylhexyl TriazoneGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Learn more about HydroxyacetophenoneWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water