Shiseido Benefiance Wrinkle Smoothing Contour Serum Versus REN Clean Skincare Bio Retinoid Youth Serum
This anti-aging serum is formulated around Retinyl Acetate and Caffeine to soften the look of wrinkles.
This anti-aging serum is formulated around Niacinamide to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
HumectantPentaerythrityl Tetraethylhexanoate
EmollientDimethicone
EmollientGlycerin
HumectantDipropylene Glycol
HumectantSd Alcohol 40-B
AstringentBehenyl Alcohol
EmollientSilica
AbrasivePEG-400
Emulsion StabilisingBatyl Alcohol
EmollientPhenoxyethanol
PreservativeMethylparaben
PreservativeCarbomer
Emulsion StabilisingDimethylacrylamide/Sodium Acryloyldimethyltaurate Crosspolymer
Trisodium EDTA
Tocopheryl Acetate
AntioxidantRetinyl Acetate
Skin ConditioningAlcohol
AntimicrobialHelianthus Annuus Seed Oil
EmollientBHT
AntioxidantPolyquaternium-51
Skin ConditioningParfum
MaskingPotassium Hydroxide
BufferingCaffeine
Skin ConditioningXanthan Gum
EmulsifyingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingPPG-3 Dipivalate
Skin ConditioningRosa Canina Fruit Oil
EmollientCI 77492
Cosmetic ColorantTocopherol
AntioxidantSapindus Mukorossi Peel Extract
Skin ConditioningLinalool
PerfumingLimonene
PerfumingSodium Metabisulfite
AntioxidantTriisostearin
Skin ConditioningUncaria Gambir Extract
AstringentCitronellol
PerfumingAngelica Keiskei Leaf/Stem Extract
Skin ConditioningTrimethylolpropane Triethylhexanoate
EmollientGeraniol
PerfumingCellulose
AbsorbentCamellia Sinensis Leaf Extract
AntimicrobialSodium Acetylated Hyaluronate
HumectantHydroxyproline
Skin ConditioningZiziphus Jujuba Fruit Extract
Skin ConditioningChlorella Vulgaris Extract
Skin ConditioningMethicone
EmollientTetradecene
EmollientEucheuma Serra/Grateloupia Sparsa/Saccharina Angustata/Ulva Linza/Undaria Pinnatifida Extract
EmollientCurcuma Longa Rhizome Extract
Skin ConditioningSaccharina Angustata/Undaria Pinnatifida Extract
EmollientPanax Ginseng Root Extract
EmollientAscorbyl Dipalmitate
AntioxidantWater, Butylene Glycol, Pentaerythrityl Tetraethylhexanoate, Dimethicone, Glycerin, Dipropylene Glycol, Sd Alcohol 40-B, Behenyl Alcohol, Silica, PEG-400, Batyl Alcohol, Phenoxyethanol, Methylparaben, Carbomer, Dimethylacrylamide/Sodium Acryloyldimethyltaurate Crosspolymer, Trisodium EDTA, Tocopheryl Acetate, Retinyl Acetate, Alcohol, Helianthus Annuus Seed Oil, BHT, Polyquaternium-51, Parfum, Potassium Hydroxide, Caffeine, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, PPG-3 Dipivalate, Rosa Canina Fruit Oil, CI 77492, Tocopherol, Sapindus Mukorossi Peel Extract, Linalool, Limonene, Sodium Metabisulfite, Triisostearin, Uncaria Gambir Extract, Citronellol, Angelica Keiskei Leaf/Stem Extract, Trimethylolpropane Triethylhexanoate, Geraniol, Cellulose, Camellia Sinensis Leaf Extract, Sodium Acetylated Hyaluronate, Hydroxyproline, Ziziphus Jujuba Fruit Extract, Chlorella Vulgaris Extract, Methicone, Tetradecene, Eucheuma Serra/Grateloupia Sparsa/Saccharina Angustata/Ulva Linza/Undaria Pinnatifida Extract, Curcuma Longa Rhizome Extract, Saccharina Angustata/Undaria Pinnatifida Extract, Panax Ginseng Root Extract, Ascorbyl Dipalmitate
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingGlycerin
HumectantNiacinamide
SmoothingCetyl Phosphate
EmulsifyingCoco-Caprylate/Caprate
EmollientSqualane
EmollientCetyl Alcohol
EmollientArginine
MaskingRosa Canina Fruit Oil
EmollientTriticum Vulgare/Aestivum Grain Extract
Skin ConditioningCrambe Abyssinica Seed Oil
Skin ConditioningBenzyl Alcohol
PerfumingAstrocaryum Murumuru Seed Butter
EmollientGlyceryl Stearate
EmollientSodium Hyaluronate
HumectantBidens Pilosa Extract
HumectantSodium Dehydroacetate
PreservativeLinum Usitatissimum Seed Oil
PerfumingSclerotium Gum
Emulsion StabilisingParfum
MaskingTocopherol
AntioxidantXanthan Gum
EmulsifyingDehydroacetic Acid
PreservativeRosa Damascena Extract
MaskingGossypium Herbaceum Seed Oil
Skin ConditioningZea Mays Oil
EmulsifyingXanthophylls
Skin ConditioningHelianthus Annuus Seed Oil
EmollientRosmarinus Officinalis Leaf Extract
AntimicrobialLactic Acid
BufferingSodium Hydroxide
BufferingCitronellol
PerfumingGeraniol
PerfumingLinalool
PerfumingWater, Caprylic/Capric Triglyceride, Glycerin, Niacinamide, Cetyl Phosphate, Coco-Caprylate/Caprate, Squalane, Cetyl Alcohol, Arginine, Rosa Canina Fruit Oil, Triticum Vulgare/Aestivum Grain Extract, Crambe Abyssinica Seed Oil, Benzyl Alcohol, Astrocaryum Murumuru Seed Butter, Glyceryl Stearate, Sodium Hyaluronate, Bidens Pilosa Extract, Sodium Dehydroacetate, Linum Usitatissimum Seed Oil, Sclerotium Gum, Parfum, Tocopherol, Xanthan Gum, Dehydroacetic Acid, Rosa Damascena Extract, Gossypium Herbaceum Seed Oil, Zea Mays Oil, Xanthophylls, Helianthus Annuus Seed Oil, Rosmarinus Officinalis Leaf Extract, Lactic Acid, Sodium Hydroxide, Citronellol, Geraniol, Linalool
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Citronellol is used to add fragrance/parfum to a product. It is often derived from plants such as roses. In fact, it can be found in many essential oils including geranium, lavender, neroli, and more. The scent of Citronellol is often described as "fresh, grassy, and citrus-like".
Since the Citronellol molecule is already unstable, Citronellol becomes irritating on the skin when exposed to air.
Citronellol is a modified terpene. Terpenes are unsaturated hydrocarbons found in plants. They make up the primary part of essential oils.
Citronellol is not able to be absorbed into deeper layers of the skin. It has low permeability,
Citronellol is also a natural insect repellent.
Learn more about CitronellolGeraniol is used to add fragrance/parfum to a product. It is the main component of citronellol. It is a monoterpenoid and an alcohol.
Monoterpenes are naturally found in many parts of different plants.
Geraniol can be found in many essential oils including Rose Oil and Citronella Oil. The scent of Geraniol is often described as "rose-like". Many foods also contain Geraniol for fruit flavoring.
Geraniol can irritate the skin when exposed to air. However, irritation depends on the ability of geraniol to penetrate into the skin. In general, geraniol is not able to penetrate skin easily.
Geraniol is colorless and has low water-solubility. However, it is soluble in common organic solvents.
Like citronellol, it is a natural insect repellent.
2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-
Learn more about GeraniolGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHelianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.
It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.
The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.
The high linoleic acid content is particularly noteworthy for acne-prone skin.
Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.
One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).
This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.
On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.
Learn more about Helianthus Annuus Seed OilLinalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.
Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.
This ingredient has a scent that is floral, spicy tropical, and citrus-like.
Learn more about LinaloolParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumRosa Canina Fruit Oil is a non-fragrant plant oil that has earned its skincare reputation through chemistry.
It's dominated by fatty acids like linoleic acid (~35-55%), alpha-linolenic acid (~17-27%), and oleic acid (~14-22%). This is the exact profile that supports skin barrier, locks in hydration, and calms inflammation.
A 2024 review found evidence for the Rosa canina species supports its use for scarring, hyperpigmentation, wrinkles, and atopic dermatitis; this was mostly credited to its vitamin C content and fatty acid composition as the primary active mechanisms.
You might see this ingredient marketed as a "natural retinol". Some rosehip seed oils contains traces of all-trans-retinoic acid but these trace amounts are far below biologically active levels.
The Cosmetic Ingredient Review Panel has deemed this ingredient safe and it's well-tolerated.
Fungal acne: The fatty acids of this oil fall into the C11-24 range that Malassezia yeast can metabolize, so this ingredient may not be fungal acne safe.
Learn more about Rosa Canina Fruit OilTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum