Paula's Choice 1% Retinol Treatment Versus First Aid Beauty Skin Lab Retinol Serum .25% Pure Concentrate
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningDimethicone
EmollientGlycerin
HumectantButylene Glycol
HumectantIsononyl Isononanoate
EmollientCastor Isostearate Succinate
Skin ConditioningGlyceryl Stearate
EmollientC12-15 Alkyl Benzoate
AntimicrobialDimethicone Crosspolymer
Emulsion StabilisingPEG-33
HumectantPolysorbate 20
EmulsifyingBehenyl Alcohol
EmollientPEG-100 Stearate
Pentaerythrityl Tetraisostearate
EmollientPolymethylsilsesquioxane
Tetrahexyldecyl Ascorbate
AntioxidantRetinol
Skin ConditioningCeramide Ng
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningPalmitoyl Hexapeptide-12
Skin ConditioningSodium Hyaluronate
HumectantDipotassium Glycyrrhizate
HumectantGlycyrrhiza Glabra Root Extract
BleachingAvena Sativa Kernel Extract
AbrasiveArctium Lappa Seed Oil
EmollientSalix Alba Extract
Skin ConditioningGlycine Soja Sterols
EmollientLecithin
EmollientAllantoin
Skin ConditioningTocopheryl Acetate
AntioxidantHydrolyzed Soy Protein
HumectantSorbitan Laurate
EmulsifyingAcetyl Dipeptide-1 Cetyl Ester
Skin ConditioningDisodium EDTA
Hydroxyethylcellulose
Emulsion StabilisingPalmitoyl Tripeptide-1
Skin ConditioningSodium Hydroxide
BufferingTribehenin
EmollientCaprylyl Glycol
EmollientEthylhexylglycerin
Skin ConditioningPentylene Glycol
Skin ConditioningPEG-75 Shea Butter Glycerides
EmulsifyingPPG-12/Smdi Copolymer
EmollientPEG-10 Phytosterol
EmulsifyingPEG-8 Dimethicone
EmulsifyingPEG-14
HumectantMagnesium Aluminum Silicate
AbsorbentArachidyl Glucoside
EmulsifyingArachidyl Alcohol
EmollientSclerotium Gum
Emulsion StabilisingCarbomer
Emulsion StabilisingPhenoxyethanol
PreservativeBenzoic Acid
MaskingWater, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Dimethicone Crosspolymer, PEG-33, Polysorbate 20, Behenyl Alcohol, PEG-100 Stearate, Pentaerythrityl Tetraisostearate, Polymethylsilsesquioxane, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Seed Oil, Salix Alba Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Sorbitan Laurate, Acetyl Dipeptide-1 Cetyl Ester, Disodium EDTA, Hydroxyethylcellulose, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Ethylhexylglycerin, Pentylene Glycol, PEG-75 Shea Butter Glycerides, PPG-12/Smdi Copolymer, PEG-10 Phytosterol, PEG-8 Dimethicone, PEG-14, Magnesium Aluminum Silicate, Arachidyl Glucoside, Arachidyl Alcohol, Sclerotium Gum, Carbomer, Phenoxyethanol, Benzoic Acid
Water
Skin ConditioningPolysorbate 80
EmulsifyingCaprylic/Capric Triglyceride
MaskingPolysorbate 20
EmulsifyingButylene Glycol
HumectantPersea Gratissima Oil
Skin ConditioningGlycerin
HumectantDimethicone
EmollientRetinol
Skin ConditioningMagnesium Ascorbyl Phosphate
AntioxidantColloidal Oatmeal
AbsorbentTocopherol
AntioxidantHydrolyzed Hyaluronic Acid
HumectantCeramide NP
Skin ConditioningAcetyl Hexapeptide-8
HumectantLinoleic Acid
CleansingAllantoin
Skin ConditioningPhytosteryl Canola Glycerides
Skin ConditioningPalmitic Acid
EmollientOleic Acid
EmollientGlycine Soja Oil
EmollientHydroxypropyl Cyclodextrin
MaskingAloe Barbadensis Leaf Juice
Skin ConditioningTriolein
Skin ConditioningCaprylyl Glycol
EmollientAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingXanthan Gum
EmulsifyingLecithin
EmollientStearic Acid
CleansingMaltodextrin
AbsorbentBHT
AntioxidantBHA
AntioxidantPhenoxyethanol
PreservativeSodium Hydroxide
BufferingPotassium Sorbate
PreservativeWater, Polysorbate 80, Caprylic/Capric Triglyceride, Polysorbate 20, Butylene Glycol, Persea Gratissima Oil, Glycerin, Dimethicone, Retinol, Magnesium Ascorbyl Phosphate, Colloidal Oatmeal, Tocopherol, Hydrolyzed Hyaluronic Acid, Ceramide NP, Acetyl Hexapeptide-8, Linoleic Acid, Allantoin, Phytosteryl Canola Glycerides, Palmitic Acid, Oleic Acid, Glycine Soja Oil, Hydroxypropyl Cyclodextrin, Aloe Barbadensis Leaf Juice, Triolein, Caprylyl Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Lecithin, Stearic Acid, Maltodextrin, BHT, BHA, Phenoxyethanol, Sodium Hydroxide, Potassium Sorbate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid or alcohol, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that causes fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Learn more about Polysorbate 20Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water