Versus

Origins Dr. Andrew Weil For Origins™ Mega-Bright Dark Spot Correcting Serum Versus Clinique Smart Clinical Repair Wrinkle Correcting Serum

Serum
Serum
American Brand United States
American Brand United States

Updated on March 06, 2025

Overview

What they are

These products are both reef safe serums. They have a total of 22 ingredients in common

Cool Features

They both contain exfoliants, hyaluronic acid, Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, dry skin, brightening skin, oily skin, reducing pores, dark spots and better texture

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Dr. Andrew Weil For Origins™ Mega-Bright Dark Spot Correcting Serum

Water

Skin Conditioning

Dimethicone

Emollient
1 / 0 Silicon Icon

Isododecane

Emollient

Cyclopentasiloxane

Emollient
Silicon Icon

Polysilicone-11

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Ascorbyl Glucoside

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

PEG-10 Dimethicone

Skin Conditioning
Silicon Icon

Citrus Aurantium Dulcis Peel Oil

Masking
Oil Icon

Pelargonium Graveolens Oil

Masking
Fragrance IconOil Icon

Cananga Odorata Flower Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen IconMay worsen Eczema Icon

Eugenia Caryophyllus Bud Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Rosa Damascena Flower Oil

Masking
Oil Icon

Jasminum Officinale Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Viola Odorata Flower/Leaf Extract

Masking

Polianthes Tuberosa Extract

Masking

Citronellol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Geraniol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Benzyl Benzoate

Antimicrobial
Fragrance IconMay cause irritation IconEU Allergen Icon

Eugenol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

PEG-6

Humectant

Rosa Roxburghii Fruit Extract

Tonic

Paeonia Albiflora Root Extract

Skin Conditioning

Gentiana Lutea Root Extract

Skin Conditioning

Hordeum Vulgare Extract

Emollient

Triticum Vulgare Germ Extract

Skin Conditioning

Hydrolyzed Rice Bran Extract

Skin Conditioning

Algae Extract

Emollient
May worsen Oily Skin Icon

Salicylic Acid

Masking
BHA IconPreservative IconGood for Oily Skin IconGood for Minimizing Pores IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Solanum Lycopersicum Fruit/Leaf/Stem Extract

Astringent

Saccharum Officinarum Extract

Moisturising

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Hordeum Distichon Extract

Skin Protecting

Polygonum Cuspidatum Root Extract

Antioxidant
Antioxidant Icon

Laminaria Digitata Extract

Skin Protecting

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Caprylyl Glycol

Emollient

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Di-C12-18 Alkyl Dimonium Chloride

Skin Conditioning

Tromethamine

Buffering

Polysorbate 60

Emulsifying
Not safe for Fungal Acne Icon

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Glycyrrhetinic Acid

Skin Conditioning

Sodium Hydroxide

Buffering

Hexylene Glycol

Emulsifying
0-2 / 0-1

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Phenoxyethanol

Preservative
Preservative Icon

CI 77891

Cosmetic Colorant
Smart Clinical Repair Wrinkle Correcting Serum

Water

Skin Conditioning

Dimethicone

Emollient
1 / 0 Silicon Icon

Isododecane

Emollient

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Polysilicone-11

Ascorbyl Glucoside

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Hypnea Musciformis Extract

Skin Protecting

Gelidiella Acerosa Extract

Skin Protecting

Sigesbeckia Orientalis Extract

Skin Conditioning

Helianthus Annuus Seed Extract

Skin Conditioning

Hordeum Vulgare Extract

Emollient

Triticum Vulgare Germ Extract

Skin Conditioning

Cucumis Sativus Fruit Extract

Emollient

Caffeine

Skin Conditioning

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Hexapeptide-12

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

PEG-10 Dimethicone

Skin Conditioning
Silicon Icon

Glycyrrhetinic Acid

Skin Conditioning

Lactis Proteinum

Skin Conditioning

Isohexadecane

Emollient

Propylene Glycol Dicaprate

Emollient

Caprylyl Glycol

Emollient

Hydroxypinacolone Retinoate

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Acetyl Glucosamine

Skin Conditioning

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

PEG-8

Humectant

Yeast Extract

Skin Conditioning
Not safe for Fungal Acne Icon

PEG-6

Humectant

Dimethyl Isosorbide

Solvent

Glyceryl Polymethacrylate

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Sodium Phosphate

Buffering

Synthetic Fluorphlogopite

Polysorbate 80

Emulsifying
0 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Carbomer

Emulsion Stabilising
1 / 0

Hexylene Glycol

Emulsifying
0-2 / 0-1

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Emulsion Stabilising

Potassium Hydroxide

Buffering

Tin Oxide

Abrasive
Exfoliant Icon

Disodium Phosphate

Buffering

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Disodium EDTA

Sodium Citrate

Buffering

Phenoxyethanol

Preservative
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

CI 77891

Cosmetic Colorant

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Emollient, Solvent

Isododecane is a fragrance, emollient, and solvent.

As an emollient, it helps your skin stay soft and hydrated. Emollients help trap moisture into your skin.

Isododecane's role as a solvent makes it a great texture enhancer. It spreads smoothly on skin and does not leave a sticky feeling behind. Isododecane also helps prevent color transfer in makeup products.

Isododecane is not absorbed into skin.

Learn more about Isododecane

We don't have a description for Polysilicone-11 yet.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Antioxidant

Ascorbyl Glucoside is a stable form of Vitamin C. It is created by combining glucose from starch.

When applied to skin, Ascorbyl Glucoside turns into Ascorbic Acid.

Ascorbyl Glucoside is an antioxidant. Antioxidants help fight free-radicals, or molecules that may damage skin cells.

It can help to reduce redness, improve skin texture, reduce the effects of aging, reduce the visibility of dark spots, and brighten skin.

Read more about other types of Vitamin C:

Learn more about Ascorbyl Glucoside
Skin Conditioning

Peg-10 Dimethicone is silicone with conditioner and emulsifier properties. It mostly acts as an emollient in skincare and and humectant in haircare.

According to the manufacturer, acidic formulations decrease the stability of this ingredient. It works best in neutral or near neutral formulations.

Humectant, Solvent

We don't have a description for PEG-6 yet.

Emollient, Skin Conditioning

We don't have a description for Hordeum Vulgare Extract yet.

Skin Conditioning, Skin Protecting

This ingredient is extracted from the germ part of the wheat plant. The germ of a plant refers to the seed embryo, or part that sprouts into a new plant.

Some studies have found wheat germ to help with wound healing.

Emollient, Emulsifying, Skin Conditioning

Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.

Our skin naturally contains cholesterol in the outermost layer. Besides cholesterol, it also contains ceramides and fatty acids. Cholesterol makes up about 1/4 of your skin's outer layer and barrier. Your skin barrier is responsible for keeping allergens and microbes out. Having a healthy skin barrier is also responsible for keeping your skin firm and plump.

Our bodies use cholestrol to create vitamin D, steroid hormones, and more.

Learn more about Cholesterol
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane
Emulsifying

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate

Ammonium Acryloyldimethyltaurate/Vp Copolymer (let's call it AAVC for short) is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.

AAVC is able to increase the consistency and viscosity of products due to its large molecule size. It also prevents ingredients from separating.

Skin Conditioning

Glycyrrhetinic acid is a compound found in licorice. It has skin conditioning, skin soothing, antibacterial, and antioxidant properties.

Not only is this a great ingredient for soothing inflammation, studies show this compound is effective at protecting skin against UV-B induced damage.

Fun fact: This ingredient is also used to mask the bitter taste of medicine.

Learn more about Glycyrrhetinic Acid
Emulsifying, Skin Conditioning, Solvent

Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.

As a surfactant, Hexylene Glycol helps gather dirt and oil on your skin to be washed away.

As an emulsifier, Hexylene Glycol helps keep water and oil together. This prevents them from separating in a product. Hexylene Glycol also thins out the texture of a product by lessening viscosity.

Hexylene Glycol has a small molecular weight.

Learn more about Hexylene Glycol
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Cosmetic Colorant

Ci 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.

It's main function is to add a white color to cosmetics. It can also be mixed with other colors to create different shades.

Ci 77891 is commonly found in sunscreens due to its ability to block UV rays.

Learn more about CI 77891

Reviews

Here's what our community thinks

Origins Dr. Andrew Weil For Origins™ Mega-Bright Dark Spot Correcting Serum 54 ingredients

Dr. Andrew Weil For Origins™ Mega-Bright Dark Spot Correcting Serum hasn't been rated yet.
Rate it now

Clinique Smart Clinical Repair Wrinkle Correcting Serum 53 ingredients

4.0 /5
from 1 rating
Absorbs Well (1) Expensive (1) Light (1)
carriedulan's avatar

Carrie Dulan

5 months ago
Review

I still try tretinion every now and again. I've never made it past 3 days a week before the flakes set in. So I use other serums like this one from Clinique. I really love this because I don't have to be as concserned with getting it in my hairline, in the small folds on the each side of my nostrils. I can put it on day (I always use sunscreen) and night and it does knock the edges off any Show more

#expensive
#light
#absorbs well
#no scent