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Product Comparison

Here's our complete breakdown comparing the ingredients, attributes, and more of Naturium Multi-Peptide Advanced Serum versus Paula's Choice 25% Vitamin C + Glutathione Clinical Serum .

Last updated on October 06, 2023. Published on January 17, 2024

Overview

What they are

These products are both cruelty-free and reef safe serums. They have a total of 17 ingredients in common

Cool Features

They both contain exfoliants and Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin and scar healing

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that need an update? Let us know.

Serum American Brand United States
Serum American Brand United States

Serum

Serums are highly concentrated with ingredients to provide skin with benefits. They should be used after cleansing and before moisturizing.

Serum

Serums are highly concentrated with ingredients to provide skin with benefits. They should be used after cleansing and before moisturizing.

Price

Shop

Buy Multi-Peptide Advanced Serum

Shop

Buy 25% Vitamin C + Glutathione Clinical Serum

Starts at $62.00

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

At a glance

Click on any of the items below to learn more

Notable Ingredients

Vitamin E (2)
Exfoliators
Peptides (3)

Benefits

Hydrating (4)
Anti-Aging (3)
Scar Healing
Brightening (3)

Concerns

May Worsen Oily Skin
Irritating
Rosacea (2)
Eczema

Notable Ingredients

Vitamin C (3)
Vitamin E
Exfoliators

Benefits

Hydrating (3)
Redness Reducing (3)
Skin Texture (4)
Anti-Aging (4)
Dark Spots (3)
Scar Healing (3)
Brightening (5)

Concerns

Irritating
Rosacea (2)
Eczema (2)
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Ingredients Compared

Ingredients that are highlighted in purple are present in both products.

Ingredients Side-by-side

Ingredients that are highlighted in purple are present in both products.

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 1.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 1.

2
What it does: Masking, Skin Conditioning
Community Rating: Mixed

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Within a product, Caprylic Triglyceride can thicken the product and make spreadability easier by dissolving clumping compounds. An added benefit of Caprylic Triglyceride is its antioxidant properties.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Caprylic Triglyceride has not been found to be toxic for human use in concentrations under 50%.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 3.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 28.

3
What it does: Skin Conditioning, Skin Protecting
Community Rating: Loved

Oryza Sativa Bran Extract comes from the outer layer of a rice kernel. It is a byproduct of milling rice, or the operation to produce a whole grain rice product.

Oryza Sativa Bran Extract is moisturizing. This is due to its components of polysaccharides and omega-3 fatty acids. It also contains calcium, selenium, phosphorus, iron, and zinc.

Oryza Sativa Bran Extract contains numerous antioxidants such as ferulic acid. Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material.

Learn more about Oryza Sativa Bran Extract

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 12.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 13.

4
What it does: Humectant, Masking, Moisturising, Skin Conditioning
Community Rating: Liked

Mannitol is a sugar alcohol. It is a humectant and moisturizes the skin. In vitro (not tested on a living organism), mannitol displays antioxidant properties.

When found in aqueous solutions, mannitol tends to become acidic. This is because it loses a hydrogen ion. This is why mannitol can often be found with pH adjusting ingredients, such as sodium bicarbonate.

Fun fact: Mannitol can be found in foods as a sweetener. It can be naturally found in mushrooms, algae, fruits, and veggies.

Learn more about Mannitol

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 13.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 27.

5
What it does: Antimicrobial, Masking, Skin Conditioning
Community Rating: Mixed

Rosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.

While Rosmarinus Officinalis Leaf Oil can be volatile due to its fragrant properties, this component is usually removed in the leaf extract.

Rosemary Leaf Extract can help protect your skin against damage from free-radical molecules. It contains many antioxidants such as rosmarinic acid and caffeic acid. Rosemarinic acid has been found to help soothe skin conditions such as eczema and acne.

Learn more about Rosmarinus Officinalis Leaf Extract

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 21.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 30.

6
What it does: Humectant, Skin Conditioning, Skin Protecting, Solvent
Community Rating: Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 23.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 4.

7
What it does: Antioxidant, Masking, Skin Conditioning
Community Rating: Liked

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 24.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 19.

8
What it does: Emulsion Stabilising
Community Rating: Disliked

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 28.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 14.

9
What it does: Emollient, Skin Conditioning, Skin Protecting
Community Rating: Very Disliked

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

Dimethicone has been found increase absorption in skin, boosting the benefits of other ingredients. While there is concern for the safety of dimethicone, the levels used in skincare are safe for use.

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 29.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 3.

10
What it does:
Community Rating: Liked

Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.

Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 30.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 22.

11
What it does: Emulsifying, Skin Conditioning
Community Rating: Liked

Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.

Hydrogenated Lecithin is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within.

The phospholipids in Hydrogenated Lecithin can produce liposomes. Liposomes help other ingredients get through the skin barrier to be better absorbed.

As an emulsifier, it prevents oil and water ingredients from separating.

Learn more about Hydrogenated Lecithin

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 32.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 9.

12
What it does: Abrasive, Absorbent
Community Rating: Disliked

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.

Silica is present naturally within the skin during collagen production and when reducing inflammation.

Learn more about Silica

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 33.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 7.

13
What it does: Emollient, Emulsifying, Emulsion Stabilising, Masking
Community Rating: Very Disliked

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Cetyl Alcohol is not related to SD alcohol, denatured alcohol, or ethyl alcohol. The FDA allows products labeled "alcohol-free" to have fatty alcohols.

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 34.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 15.

14
What it does: Emulsifying
Community Rating: Very Disliked

Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.

Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.

In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.

Polysorbates are commonly used in medicine and foods.

Learn more about Polysorbate 60

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 36.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 31.

15
What it does: Emulsifying
Community Rating: Very Disliked

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

As an emulsifier, Sorbitan Isostearate prevents oils and water from separating.

Due to its isostearic acid base, it may not be safe for Malassezia or fungal acne.

Learn more about Sorbitan Isostearate

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 37.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 32.

16
What it does: Emulsifying, Emulsion Stabilising, Gel Forming, Skin Conditioning
Community Rating: Disliked

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 43.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 12.

17
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Naturium Multi-Peptide Advanced Serum contains this as ingredient number 47.

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum contains this as ingredient number 40.

Here's what our community thinks of the ingredients in these two products.

38% are loved or liked
13% have mixed ratings
34% are disliked or very disliked
15% have no rating yet
50% are loved or liked
10% have mixed ratings
28% are disliked or very disliked
13% have no rating yet

Usage

Here's some more info on how this product is used by our community.

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Reviews

Here's what our community thinks

Naturium Multi-Peptide Advanced Serum 47 ingredients

4.5 /5
from 2 ratings

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum 40 ingredients

25% Vitamin C + Glutathione Clinical Serum hasn't been rated yet.
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