Lancôme Advanced Génifique Yeux Light-Pearl Eye & Lash Enhancing Concentrate Versus SK-II R.N.A. POWER Anti-Aging Eye Cream
This anti-aging eye moisturizer is formulated around Bifida Ferment Lysate and Adenosine to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging eye moisturizer is formulated around Galactomyces Ferment Filtrate and Niacinamide to soften the look of wrinkles and hydrate skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningBifida Ferment Lysate
Skin ConditioningPropanediol
SolventGlycerin
HumectantAlcohol Denat.
AntimicrobialDimethicone
EmollientC13-14 Isoparaffin
EmollientEscin
TonicTocopheryl Acetate
AntioxidantSodium Benzoate
MaskingPhenoxyethanol
PreservativeAdenosine
Skin ConditioningCaffeine
Skin ConditioningPolyacrylamide
Chlorphenesin
AntimicrobialPolymethylsilsesquioxane
Chlorella Vulgaris Extract
Skin ConditioningSalicyloyl Phytosphingosine
Skin ConditioningDimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingDimethiconol
EmollientPentaerythrityl Tetraethylhexanoate
EmollientXanthan Gum
EmulsifyingCaprylic/Capric Triglyceride
MaskingBis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone
EmollientBHT
AntioxidantLaureth-7
EmulsifyingWater, Bifida Ferment Lysate, Propanediol, Glycerin, Alcohol Denat., Dimethicone, C13-14 Isoparaffin, Escin, Tocopheryl Acetate, Sodium Benzoate, Phenoxyethanol, Adenosine, Caffeine, Polyacrylamide, Chlorphenesin, Polymethylsilsesquioxane, Chlorella Vulgaris Extract, Salicyloyl Phytosphingosine, Dimethicone/Vinyl Dimethicone Crosspolymer, Ammonium Polyacryloyldimethyl Taurate, Dimethiconol, Pentaerythrityl Tetraethylhexanoate, Xanthan Gum, Caprylic/Capric Triglyceride, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, BHT, Laureth-7
Water
Skin ConditioningGlycerin
HumectantGalactomyces Ferment Filtrate
HumectantNiacinamide
SmoothingIsohexadecane
EmollientButylene Glycol
HumectantPentylene Glycol
Skin ConditioningIsopropyl Isostearate
EmollientPetrolatum
EmollientDimethicone
EmollientCaprylic/Capric Triglyceride
MaskingVinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
Polyacrylamide
Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Skin ConditioningStearyl Alcohol
EmollientCetyl Alcohol
EmollientC13-14 Isoparaffin
EmollientBehenyl Alcohol
EmollientTocopheryl Acetate
AntioxidantPolymethylsilsesquioxane
Panthenol
Skin ConditioningNylon-12
Benzyl Alcohol
PerfumingDimethiconol
EmollientMethylparaben
PreservativePEG-100 Stearate
SurfactantLaureth-7
EmulsifyingCetearyl Glucoside
EmulsifyingCetearyl Alcohol
EmollientStearic Acid
CleansingMica
Cosmetic ColorantDisodium EDTA
ChelatingPropylparaben
PreservativeSodium PEG-7 Olive Oil Carboxylate
EmulsifyingEthylparaben
PreservativePEG-7 Glyceryl Cocoate
EmulsifyingChlorella Vulgaris Extract
Skin ConditioningSodium Hydroxide
BufferingHydrolyzed Lupine Protein
Skin ConditioningDecyl Glucoside
CleansingMedicago Sativa Extract
TonicPhenoxyethanol
PreservativeLactic Acid
BufferingSodium Benzoate
MaskingHydrolyzed Soy Protein
HumectantPolyquaternium-7
Tin Oxide
AbrasiveEthylhexylglycerin
Skin ConditioningPalmitoyl Dipeptide-7
Skin ConditioningHydrolyzed Yeast Protein
Skin ConditioningAcanthopanax Senticosus Root Extract
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningMethylsilanol Tri-PEG-8 Glyceryl Cocoate
EmulsifyingAmmonium Polyacrylate
StabilisingMethicone
EmollientTocopherol
AntioxidantCynara Scolymus Leaf Extract
Skin ConditioningBHT
AntioxidantParfum
MaskingLimonene
PerfumingLinalool
PerfumingCI 77891
Cosmetic ColorantCI 77492
Cosmetic ColorantWater, Glycerin, Galactomyces Ferment Filtrate, Niacinamide, Isohexadecane, Butylene Glycol, Pentylene Glycol, Isopropyl Isostearate, Petrolatum, Dimethicone, Caprylic/Capric Triglyceride, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Polyacrylamide, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Stearyl Alcohol, Cetyl Alcohol, C13-14 Isoparaffin, Behenyl Alcohol, Tocopheryl Acetate, Polymethylsilsesquioxane, Panthenol, Nylon-12, Benzyl Alcohol, Dimethiconol, Methylparaben, PEG-100 Stearate, Laureth-7, Cetearyl Glucoside, Cetearyl Alcohol, Stearic Acid, Mica, Disodium EDTA, Propylparaben, Sodium PEG-7 Olive Oil Carboxylate, Ethylparaben, PEG-7 Glyceryl Cocoate, Chlorella Vulgaris Extract, Sodium Hydroxide, Hydrolyzed Lupine Protein, Decyl Glucoside, Medicago Sativa Extract, Phenoxyethanol, Lactic Acid, Sodium Benzoate, Hydrolyzed Soy Protein, Polyquaternium-7, Tin Oxide, Ethylhexylglycerin, Palmitoyl Dipeptide-7, Hydrolyzed Yeast Protein, Acanthopanax Senticosus Root Extract, Palmitoyl Pentapeptide-4, Methylsilanol Tri-PEG-8 Glyceryl Cocoate, Ammonium Polyacrylate, Methicone, Tocopherol, Cynara Scolymus Leaf Extract, BHT, Parfum, Limonene, Linalool, CI 77891, CI 77492
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
BHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTC13-14 Isoparaffin is a synthetic emollient, solvent, and thickening agent. It helps soften skin and improves spreadability without leaving a greasy residue.
This ingredient has been found to be non-sensitizing and safe for use in cosmetics.
Two things floating around online that cause fear-mongering:
There's one scary-sounding study related to kidney tumors in male rats; this depends on a protein called alpha-2u-globulin that binds the ingredient and clogs up kidney cells. Female rats barely make this protein, and humans don't make it at all so this effect cannot happen to us. Regulatory bodies have states this rat-only pathway shouldn't be used to judge human risk.
The other thing you'll see is 1,4-dioxane being a trace byproduct that can form during manufacturing of petroleum-derived ingredients. This is a real, but heavily managed/monitored issue. This byproduct is removed through purification steps before the ingredients goes into the formula. Regulatory bodies also actively monitor residual levels for safety.
One last thing to note: this ingredient is a pure hydrocarbon with no fatty-acid or ester chains for Malassezia to feed on, so it's considered fungal acne safe.
Learn more about C13-14 IsoparaffinCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideChlorella Vulgaris Extract comes from a single-celled green freshwater algae.
The version used in skincare is almost always a water or glycerin-based extract that is basically the algae's amino acids, peptides, sugars, and chlorophyll pigments.
It acts as a skin-conditioning agent and the research behind it at this time is mostly lab-dish rather than human trials.
Isolated Chlorella peptides inhibit collagenase and elastase (the enzymes that chew up collagen and elastin) and mop up free radicals in test-tube assays. Another study found a Chlorella gel sped up wound healing in mice. Many of the firming or dark-circle claims come from the ingredient supplier's own studies.
Suppliers suggest using 1-2% of the trade version (Water/Glycerin + Chlorella Vulgaris Extract) in a finished formula which means the actual algae solids are a fraction of a percent.
Allergy risk is low and topical reactions are rare; the 2020 anaphylaxis case came from eating Chlorella supplements and not from putting it on skin.
However, patch testing is sensible if you have reacted to algae before.
The "chlorella is high in iodine so it breaks you out" line borrows from marine seaweed. Freshwater Chlorella isn't a notable iodine source unless it's deliberately grown in iodine-enriched medium.
Just so you know, many lists give algae a comedogenic rating of 5 and that number doesn't come from anywhere; it's not in the original rabbit-ear studies that most comedogenic ratings trace back to.
The reasoning behind the reputation is that seaweed is high in iodine and iodine can trigger acne-like breakouts when eaten. This traces back to a 1976 letter in Archives of Dermatology describing two women whose breakouts cleared after they stopped taking high-dose kelp supplements orally.
And the reaction of these two women wasn't clogged pores at all: it was an iodine-triggered pustular rash. Later research found normal dietary iodine doesn't meaningfully affect acne either and nobody has shown topical algae delivers enough iodine to matter.
Learn more about Chlorella Vulgaris ExtractDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeDimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLaureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.
This ingredient is an emulsifier and cleansing ingredient. As an emulsifier, it is used to prevent ingredients from separating. It also helps cleanse the skin by gathering dirt, oil, and pollutants to be rinsed away.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolPolyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.
Polyacrylamide is low-toxicity. If source properly, it is deemed safe to use in cosmetics.
It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.
We recommend speaking with a professional if you have concerns.
Learn more about PolyacrylamidePolymethylsilsesquioxane is a silicone used as a film forming agent.
When applied to the skin, this ingredient creates an invisible film on the surface. This film still allows oxygen to pass through, but prevents moisture from escaping. This can help condition and hydrate the skin. It also leaves a silky feel when applied.
Polymethylsilsesquioxane has not been shown to clog pores. It has been deemed safe to use up to 55%, but most cosmetics use much less.
If you have concerns about using this ingredient, we recommend speaking with a professional.
Learn more about PolymethylsilsesquioxaneSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water