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Product Comparison

Here's our complete breakdown comparing the ingredients, attributes, and more of KIKO Milano Smart Detox Drops versus SkinMedica HA5 Rejuvenating Hydrator .

Published on November 19, 2023

Overview

What they are

These products are both reef safe serums. They have a total of 19 ingredients in common

Cool Features

They both contain exfoliants, hyaluronic acid and Vitamin E

Suited For

They're both likely to be good for dry skin, brightening skin and better texture

Free From

They both do not contain any parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that need an update? Let us know.

Serum Italian Brand Italy
Serum American Brand United States

Serum

Serums are highly concentrated with ingredients to provide skin with benefits. They should be used after cleansing and before moisturizing.

Serum

Serums are highly concentrated with ingredients to provide skin with benefits. They should be used after cleansing and before moisturizing.

Price

Shop

Buy Smart Detox Drops

Shop

Buy HA5 Rejuvenating Hydrator

Starts at $144.50

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

At a glance

Click on any of the items below to learn more

Notable Ingredients

Vitamin E (2)
Exfoliators
Hyaluronic Acid

Benefits

Hydrating (3)
Skin Texture
Brightening (3)

Concerns

Drying (2)
May Worsen Oily Skin (4)
Irritating (2)
Rosacea (5)
Eczema (7)

Notable Ingredients

Vitamin E
Exfoliators (2)
Hyaluronic Acid (3)

Benefits

Hydrating (2)
Skin Texture
Brightening (2)

Concerns

May Worsen Oily Skin (2)
Rosacea (2)
Eczema (2)
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Ingredients Compared

Ingredients that are highlighted in purple are present in both products.

Ingredients Side-by-side

Ingredients that are highlighted in purple are present in both products.

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

KIKO Milano Smart Detox Drops contains this as ingredient number 1.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 1.

2
What it does:
Community Rating: Disliked

We don't have a description for Polysilicone-11.

KIKO Milano Smart Detox Drops contains this as ingredient number 5.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 7.

3
What it does: Humectant, Skin Conditioning, Skin Protecting, Solvent
Community Rating: Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

KIKO Milano Smart Detox Drops contains this as ingredient number 6.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 4.

We don't have a description for Hdi/Trimethylol Hexyllactone Crosspolymer.

KIKO Milano Smart Detox Drops contains this as ingredient number 8.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 3.

5
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

KIKO Milano Smart Detox Drops contains this as ingredient number 9.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 44.

6
What it does: Humectant, Moisturising
Community Rating: Loved

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.

Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.

In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.

Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.

Learn more about Trehalose

KIKO Milano Smart Detox Drops contains this as ingredient number 14.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 18.

7
What it does: Buffering, Humectant, Skin Conditioning
Community Rating: Liked

Urea is also called carbamide and is the diamide of carbonic acid. In cosmetics, urea is used to hydrate the skin. It also provides exfoliation in higher concentrations.

As a humectant, urea helps draw moisture from the air and from deep within the skin. This helps hydrate your skin. Studies show urea is an effective moisturizer for dry skin conditions. 40% urea is typical in medications for treating eczema and other skin conditions.

Urea has the strongest exfoliation effect in concentrations higher than 10%. It is a keratolytic agent, meaning it breaks down the keratin protein in the top layer of skin. This helps remove dead skin cells and flaking skin.

In medicine, urea has been shown to help increase the potency of other ingredients, such as fungal treatments.

Humans and animals use urea to metabolize nitrogen-containing compounds. Urea is highly soluble in water. Once dissolved, it is neither acidic nor alkaline.

Learn more about Urea

KIKO Milano Smart Detox Drops contains this as ingredient number 15.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 19.

8
What it does: Antioxidant, Skin Conditioning
Community Rating: Liked

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate

KIKO Milano Smart Detox Drops contains this as ingredient number 16.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 32.

9
What it does: Masking, Skin Conditioning
Community Rating: Loved

Serine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.

Amino-acids help give keep our skin hydrated. They play an important role in the skin barrier, which keeps the skin plump and firm.

Serine is a non-essential amino acid, meaning we don't need to obtain it from eating foods.

Learn more about Serine

KIKO Milano Smart Detox Drops contains this as ingredient number 20.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 20.

10
What it does: Skin Conditioning, Solvent
Community Rating: Mixed

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can help thicken or emulsify a product. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol

KIKO Milano Smart Detox Drops contains this as ingredient number 21.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 26.

11
What it does: Skin Conditioning
Community Rating: Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

KIKO Milano Smart Detox Drops contains this as ingredient number 25.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 43.

12
What it does: Abrasive, Absorbent
Community Rating: Disliked

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.

Silica is present naturally within the skin during collagen production and when reducing inflammation.

Learn more about Silica

KIKO Milano Smart Detox Drops contains this as ingredient number 32.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 40.

13
What it does: Masking
Community Rating: Very Disliked

Algin is brown algae. Algae is an informal term for a group of aquatic organisms that can photosynthesize. It is estimated there are at least 30,000 types of Algae.

Algae contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

KIKO Milano Smart Detox Drops contains this as ingredient number 34.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 21.

14
What it does:
Community Rating: Disliked

We don't have a description for Glyceryl Polyacrylate.

KIKO Milano Smart Detox Drops contains this as ingredient number 35.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 28.

15
What it does: Emollient, Humectant, Skin Conditioning
Community Rating: Liked

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol

KIKO Milano Smart Detox Drops contains this as ingredient number 36.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 22.

16
What it does: Humectant, Skin Conditioning
Community Rating: Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate

KIKO Milano Smart Detox Drops contains this as ingredient number 37.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 11.

17
What it does:
Community Rating: Liked

We don't have a description for Pullulan.

KIKO Milano Smart Detox Drops contains this as ingredient number 38.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 23.

18
What it does: Buffering, Masking

We don't have a description for Disodium Phosphate.

KIKO Milano Smart Detox Drops contains this as ingredient number 39.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 24.

19
What it does: Buffering
Community Rating: Liked

Potassium Phosphate is the term for the salts of potassium and phosphate ions. Our bodies naturally create and use potassium phosphate.

In cosmetics, potassium phosphate is used to adjust the pH level of products. Our skin has a natural pH level. Maintaining this pH level is important for our skin barrier. If the skin barrier is disrupted, our skin can experience dehydration and irritation.

This ingredient is used in medicine to help treat low blood levels of phosphorus.

Learn more about Potassium Phosphate

KIKO Milano Smart Detox Drops contains this as ingredient number 43.

SkinMedica HA5 Rejuvenating Hydrator contains this as ingredient number 25.

Here's what our community thinks of the ingredients in these two products.

40% are loved or liked
10% have mixed ratings
32% are disliked or very disliked
18% have no rating yet
36% are loved or liked
18% have mixed ratings
29% are disliked or very disliked
18% have no rating yet

Usage

Here's some more info on how this product is used by our community.

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