ISOI Blemish Care Eye & Wrinkle Patch Versus Peter Thomas Roth Even Smoother Glycolic Retinol Hydra-Gel Eye Patches
This brightening eye mask is formulated around Niacinamide and Rosa Damascena Flower Water to fade the look of dark spots and soften the look of wrinkles.
This smoothing eye mask is formulated around Glycolic Acid and Retinol to refine skin texture and soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningDipropylene Glycol
HumectantGlycerin
HumectantNiacinamide
Smoothing1,2-Hexanediol
Skin ConditioningChondrus Crispus Extract
Skin ConditioningRosa Damascena Flower Water
MaskingCeratonia Siliqua Gum
EmollientRosa Damascena Flower Oil
MaskingRosa Hybrid Flower
Skin ConditioningSodium Hyaluronate
HumectantSodium Acetylated Hyaluronate
HumectantHydrolyzed Hyaluronic Acid
HumectantHydrolyzed Sodium Hyaluronate
Skin ConditioningHyaluronic Acid
HumectantHydroxypropyltrimonium Hyaluronate
Potassium Hyaluronate
Skin ConditioningSodium Hyaluronate Crosspolymer
HumectantHippophae Rhamnoides Fruit Extract
Skin ConditioningRubus Idaeus Fruit Extract
AstringentRubus Fruticosus Fruit Extract
AstringentEuterpe Oleracea Fruit Extract
Vaccinium Myrtillus Fruit Extract
Skin ConditioningVaccinium Macrocarpon Fruit Extract
AstringentRibes Nigrum Fruit Extract
AstringentVaccinium Angustifolium Fruit Extract
Skin ProtectingHouttuynia Cordata Extract
Skin ConditioningCentella Asiatica Extract
CleansingCalendula Officinalis Flower Extract
MaskingScutellaria Baicalensis Root Extract
AstringentGlycyrrhiza Glabra Root Extract
BleachingGlutathione
Allantoin
Skin ConditioningBetaine
HumectantTrehalose
HumectantPanthenol
Skin ConditioningDipotassium Glycyrrhizate
HumectantAdenosine
Skin ConditioningPotassium Chloride
Sucrose
HumectantXanthan Gum
EmulsifyingCellulose Gum
Emulsion StabilisingPolyglyceryl-10 Oleate
Skin ConditioningGlyceryl Caprylate
EmollientPelargonium Graveolens Flower Oil
MaskingCitrus Aurantium Dulcis Peel Oil
MaskingCitronellol
PerfumingGeraniol
PerfumingLinalool
PerfumingCI 77491
Cosmetic ColorantWater, Dipropylene Glycol, Glycerin, Niacinamide, 1,2-Hexanediol, Chondrus Crispus Extract, Rosa Damascena Flower Water, Ceratonia Siliqua Gum, Rosa Damascena Flower Oil, Rosa Hybrid Flower, Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hippophae Rhamnoides Fruit Extract, Rubus Idaeus Fruit Extract, Rubus Fruticosus Fruit Extract, Euterpe Oleracea Fruit Extract, Vaccinium Myrtillus Fruit Extract, Vaccinium Macrocarpon Fruit Extract, Ribes Nigrum Fruit Extract, Vaccinium Angustifolium Fruit Extract, Houttuynia Cordata Extract, Centella Asiatica Extract, Calendula Officinalis Flower Extract, Scutellaria Baicalensis Root Extract, Glycyrrhiza Glabra Root Extract, Glutathione, Allantoin, Betaine, Trehalose, Panthenol, Dipotassium Glycyrrhizate, Adenosine, Potassium Chloride, Sucrose, Xanthan Gum, Cellulose Gum, Polyglyceryl-10 Oleate, Glyceryl Caprylate, Pelargonium Graveolens Flower Oil, Citrus Aurantium Dulcis Peel Oil, Citronellol, Geraniol, Linalool, CI 77491
Water
Skin ConditioningGlycerin
HumectantChondrus Crispus Powder
AbrasiveArginine
MaskingGlycolic Acid
BufferingRetinol
Skin ConditioningCaffeine
Skin ConditioningNiacinamide
SmoothingLactobacillus Ferment Lysate
Skin ConditioningCamellia Sinensis Leaf Extract
AntimicrobialPunica Granatum Extract
AstringentAdenosine
Skin ConditioningButyrospermum Parkii Butter
Skin ConditioningTocopheryl Acetate
AntioxidantPersea Gratissima Oil
Skin ConditioningLecithin
EmollientLactobacillus Ferment
Skin ConditioningAllantoin
Skin ConditioningSodium Hyaluronate
HumectantTocopherol
AntioxidantCeratonia Siliqua Gum
EmollientChondrus Crispus Extract
Skin ConditioningXanthan Gum
EmulsifyingChlorphenesin
AntimicrobialPotassium Chloride
Polyglyceryl-10 Laurate
Skin ConditioningDextrin
AbsorbentPolyglyceryl-10 Myristate
Skin ConditioningCI 77491
Cosmetic ColorantDisodium EDTA
ChelatingSynthetic Fluorphlogopite
Silica
AbrasiveCI 77007
Cosmetic ColorantButylene Glycol
HumectantPentylene Glycol
Skin ConditioningAlcohol
AntimicrobialTin Oxide
AbrasivePolysorbate 20
EmulsifyingPotassium Phosphate
BufferingCI 77891
Cosmetic ColorantPhenoxyethanol
PreservativeWater, Glycerin, Chondrus Crispus Powder, Arginine, Glycolic Acid, Retinol, Caffeine, Niacinamide, Lactobacillus Ferment Lysate, Camellia Sinensis Leaf Extract, Punica Granatum Extract, Adenosine, Butyrospermum Parkii Butter, Tocopheryl Acetate, Persea Gratissima Oil, Lecithin, Lactobacillus Ferment, Allantoin, Sodium Hyaluronate, Tocopherol, Ceratonia Siliqua Gum, Chondrus Crispus Extract, Xanthan Gum, Chlorphenesin, Potassium Chloride, Polyglyceryl-10 Laurate, Dextrin, Polyglyceryl-10 Myristate, CI 77491, Disodium EDTA, Synthetic Fluorphlogopite, Silica, CI 77007, Butylene Glycol, Pentylene Glycol, Alcohol, Tin Oxide, Polysorbate 20, Potassium Phosphate, CI 77891, Phenoxyethanol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinCeratonia Siliqua Gum is extracted from the seeds of the carob tree. You might know this ingredient as Carob Gum or Locust Bean Gum. It is used to stabilize other ingredients and improve the texture of products.
Carob gum is made up of long-chain polysaccharides. This makes it a natural thickener.
Yes! This ingredient comes from the seeds of a tree. The name 'Locust Bean Gum' can be misleading.
Learn more about Ceratonia Siliqua GumThis ingredient comes from the red seaweed that grows along the North Atlantic. It's the same alga that gives us carrageenan, the thickener in your oat milk.
The extract is mostly big sulfated sugar molecules (polysaccharides) plus some minerals and protein.
What those sugars do is simple and useful: they hold onto water and form a light film on the skin. That means they boost hydration, add a bit of slip, and leave a soft, cushiony feel.
It also helps with texture and thickness.
You'll see claims about anti-aging and "second skin" effects but those come mostly from supplier marketing.
The real research is cell-culture stuff and there's no human trial on this ingredient specifically (yet). So for now, treat it as a nice hydrator and texture helper, not an active.
Safety-wise, it's pretty solid. The Cosmetic Ingredient Review panel rated it safe as used, human sensitization tests came back negative, and it wasn't irritating in skin or eye tests.
Typical use levels are 0.5% or lower.
You'll see algae listed as a 5/5 on a lot of pore-clogging charts and that number doesn't come from anywhere; it's not in the original rabbit-ear studies that most comedogenic ratings trace back to.
The reasoning behind the reputation is that seaweed is high in iodine and iodine can trigger acne-like breakouts when eaten. This traces back to a 1976 letter in Archives of Dermatology describing two women whose breakouts cleared after they stopped taking high-dose kelp supplements orally.
And the reaction of these two women wasn't clogged pores at all: it was an iodine-triggered pustular rash. Later research found normal dietary iodine doesn't meaningfully affect acne either and nobody has shown topical algae delivers enough iodine to matter.
What we do have is dozens of brown and red algae ingredients found to be non-irritating and non-sensitizing, and a handful of studies that found algae compounds may actually help acne.
However, plenty of people do report breaking out from algae-containing products. Skin is individual and it's worth avoiding if yours has reacted to algae before.
Learn more about Chondrus Crispus ExtractCi 77491 is also hydrated iron III oxide. It's sole purpose is to give a red/pink hue to products.
Iron III oxides are classified as inorganic chemicals for coloring.
Synthetically created Ci 77491 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.
Learn more about CI 77491Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideWe don't have a description for Potassium Chloride yet.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum