Versus

Glymed Plus Bio Renewal Serum Versus Shaklee Youth Moisture Activating Serum

Serum
Serum
American Brand United States
American Brand United States

Updated on September 29, 2025

Overview

What they are

These products are both vegan and cruelty-free serums. They have a total of 14 ingredients in common

Cool Features

They both contain hyaluronic acid, Vitamin C and Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing and better texture

Free From

They both do not contain any harsh alcohols, parabens, silicones or sulfates

What's Inside

They both contain common allergens, fragrances and oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Bio Renewal Serum
Youth Moisture Activating Serum

Water

Skin Conditioning

Prunus Amygdalus Dulcis Oil

Skin Conditioning
3 / 0 Oil IconHelps hydrate Dry Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Dipentaerythrityl Hexacaprylate/Hexacaprate

Emulsifying

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Sorbitol

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Opuntia Tuna Flower/Stem Extract

Skin Conditioning

Hydrolyzed Sodium Hyaluronate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Scar Healing Icon

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Lotus Japonicus Symbiosome Extract

Antioxidant
Antioxidant Icon

Schisandra Chinensis Fruit Extract

Skin Conditioning

Malus Domestica Fruit Cell Culture Extract

Skin Conditioning

Vitis Rotundifolia Fruit Extract

Skin Conditioning

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Magnesium Ascorbyl Phosphate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Vitis Vinifera Seed Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Scar Healing Icon

Eugenia Caryophyllus Leaf Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Phytosteryl Canola Glycerides

Skin Conditioning
Not safe for Fungal Acne Icon

Oleic Acid

Emollient
May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Palmitic Acid

Emollient
2 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Betaine

Humectant
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots Icon

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Carrageenan

May worsen Oily Skin Icon

Cellulose Gum

Emulsion Stabilising
0 / 0

Ethylhexylglycerin

Skin Conditioning

Sodium Hydroxide

Buffering

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Lactobacillus/Soybean Ferment Extract

Skin Conditioning

Viscum Album Leaf Extract

Soothing

Acacia Decurrens Extract

Astringent

Pentylene Glycol

Skin Conditioning

Imperata Cylindrica Root Extract

Skin Conditioning

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Xanthan Gum

Emulsifying

Phenoxyethanol

Preservative
Preservative Icon

Stearic Acid

Cleansing
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Triolein

Skin Conditioning
Not safe for Fungal Acne Icon

Superoxide Dismutase

Antioxidant
Antioxidant IconHelps with Anti-Aging Icon

Cananga Odorata Flower Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen IconMay worsen Eczema Icon

Coriandrum Sativum Fruit Oil

Masking
Fragrance IconOil IconNot safe for Fungal Acne Icon

Eugenol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.

This ingredient has emollient and emulsifying properties.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Some other names for this ingredient include soy lecithin and deoiled soy lecithin.

Learn more about Lecithin
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Humectant, Masking, Skin Conditioning

Sorbitol is a sugar alcohol. It is a hydrating and moisturizing agent created from the reduction process of glucose.

Most sorbitol is usually made from potato starch. It is also found in fruits such as apples and pears.

As a humectant, Sorbitol helps draw water to the skin. This helps keep the skin hydrated. Sorbitol also helps create a thicker texture in products. You might find sorbitol in your toothpaste and other gels.

It is a non-irritating ingredient that is great for those with dry skin.

Sorbitol is a prebiotic. It helps promote the growth of healthy bacteria on your skin. The bacteria on your skin form a microbiome. This microbiome helps protect your skin from infection and harmful bacteria.

Learn more about Sorbitol
Antimicrobial, Antioxidant, Skin Protecting

Vitis Vinifera Seed Extract comes from the grape vine. Grape seeds are a byproduct of creating grape juice or wine.

The components of grape seeds have many skin benefits. Research has found it to be antimicrobial and anti-inflammatory. It also contains many potent antioxidants such as Vitamin E , Vitamin C, proanthocyanidins, polyphenols, flavonoids, and anthocyanins. Proanthocyanidin has been shown to help even out skin tone.

Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Antioxidants help stabilize free-radicals by donating extra electrons. Grape seed extract may help reduce the signs of aging.

The antimicrobial properties of grape seed may help treat acne. However, more research is needed to support this claim.

Grape seed has also been found to help absorb UV rays. Grape seed extract should not replace your sunscreen.

Learn more about Vitis Vinifera Seed Extract
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

2 Routines
50% use in am
50% use in pm
100% use every day