Make p:rem Idebenone Lifting Ampoule

Make p:rem Idebenone Lifting Ampoule

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Overview

What it is

Ampoule with 44 ingredients that contains ceramides and hyaluronic acid

Cool Features

It is cruelty-free and reef safe

Suited For

It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots

Free From

It doesn't contain any harsh alcohols, parabens, silicones or sulfates

Fun facts

Make p:rem is from South Korea.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

About this product

Ingredients List

Dive into the full list of ingredients.

21
15
8

Rosa Canina Fruit Extract

Astringent
Good for Scar Healing Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Methylpropanediol

Solvent

Hydroxydecyl Ubiquinone

Antioxidant
Antioxidant Icon

Bisabolol

Masking
Helps reduce irritation Icon

Key Ingredients

Benefits

Concerns

Ingredients Explained

Astringent, Skin Conditioning, Tonic

Rosa Canina Fruit Extract is from Rosehip. Rosehips are a fruit from a wild rose bush native to Eurasia and Africa.

Rosehip contains Vitamin C, Vitamin E, fatty acids and linolenic acids that hydrate skin. Having hydrated skin helps reduce the appearance of fine-lines and wrinkles.

Vitamins C and E are potent antioxidants and may help with anti-aging. The fatty acids are emollients that help soften and hydrate your skin.

Another potent vitamin found in rosehip is Vitamin A, or retinol. Retinol encourages collagen production in the skin.

Rosehip extract may help with brightening the skin. Several components, such as beta-carotene, are able to reduce pigmentation caused by sun damage.

Learn more about Rosa Canina Fruit Extract
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

Methylpropanediol is a synthetic solvent and humectant.

As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.

Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.

Learn more about Methylpropanediol

Hydroxydecyl Ubiquinone is an antioxidant.

Masking, Skin Conditioning, Soothing

Bisabolol is famous for its skin soothing properties. It does this by blocking inflammatory signals, helping to reduce your body's reaction to irritation.

This ingredient also interferes with the process of hyperpigmentation. This can help with reducing dark spots and uneven tone.

Bisabolol is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. By fighting these free-radicals, Bisabolol may slow down signs of aging.

Studies have shown Bisabolol to have antimicrobial properties and may be a fungicide. These properties help preserve a product's shelf life.

All these properties makes bisabolol a great skin barrier helper ingredient.

Bisabolol also helps the absorption of other ingredients.

Note: Synthetic Bisabolol has been shown to be less effective.

Learn more about Bisabolol
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane
Humectant, Skin Conditioning

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

This ingredient is best for improving hydration and soothing irritated skin. Studies also show it helps even out skin tone.

Fun fact: Betaine is naturally created in the skin and body. The kind found within cosmetic products can be either plant-derived or synthetic.

Learn more about Betaine
Skin Conditioning

Butyrospermum Parkii Butter is a plant lipid from the fruit of the Shea Tree. It is an effective skin hydrator and emollient.

Emollients help soothe and soften your skin. It does this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.

Shea butter is rich in antioxidants. Antioxidants help fight free-radicals, or molecules that may harm the body. It is also full of fatty acids including stearic acid and linoleic acid. These acids help replenish the skin and keep skin moisturized.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

Shea butter may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Learn more about Butyrospermum Parkii Butter
Humectant, Skin Conditioning

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.

One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.

Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.

Read more about other common forms of hyaluronic acid:

Learn more about Hydrolyzed Hyaluronic Acid
Skin Conditioning

Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi. It hydrates the skin and helps boost your skin's natural barrier.

As an antioxidant, beta-glucan helps fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Studies show this ingredient may be an effective wrinkle reducer as it can deeply penetrate into skin. It has also been show to help with wound healing.

Learn more about Beta-Glucan
Skin Conditioning

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP

Learn more about Ceramide NP
Skin Conditioning

Ceramide AS is a type of Ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Skin Conditioning

Ceramide AP is a type of Ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. Having a strong skin barrier leads to more firm and hydrated skin.

They are known for their ability to hold water and thus are a great ingredient for dry skin. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide NP Ceramide EOP

Learn more about Ceramide AP
Skin Conditioning

Ceramide NS is a type of Ceramide. Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramide NG,Ceramide NS,1,3-Hexadecanediol, 2-Hexadecanamide,Palmitoyl-C16-Dihydrosphingosine,1-Stearoyl-C18-Sphingosine

Skin Conditioning

Ceramide EOP is a type of Ceramide.

EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.

Ceramides are intercellular lipids naturally found in our skin. They bind dead skin cells together to create a barrier. The ceramides in our skin have the ability to hold water to keep our skin hydrated.

Ceramides are an important building block for our skin barrier. A strong skin barrier helps with:

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here:

Learn more about Ceramide EOP
Emollient, Humectant, Masking

Algae Extract is a confusing name. This is because algae is an informal term for a group of 30,000 aquatic organisms that can photosynthesize.

The term 'algae extract' can refer to any one, or a blend of, the 30,000 types.

Algae is rich in antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Algae can also help with soothing and hydrating skin.

Many different types of algae have different benefits.

Learn more about Algae Extract
Skin Conditioning

Eclipta Prostrata Leaf Extract comes from the false daisy plant. False daisy contains antioxidant compounds such as flavonoids.

One study found false daisy to absorb UVA and UVB radiation. However, this should not replace your sunscreen.

False daisy is used in both traditional medicines and foods throughout Southeast Asia and India.

Learn more about Eclipta Prostrata Leaf Extract

Citrus Aurantium Bergamia Fruit Oil is the oil from the bergamot orange. It is native to Italy.

This ingredient is used to add fragrance to products. It contains limonene, linalool, and linalyl acetate.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.

When used topically, Citrus Aurantium Bergamia Fruit Oil is a photosensitizer due to its furanocoumarins. Photosensitizers make the skin and eyes much more sensitive to sunlight. Photosensitizers are linked to skin cancer.

However, more cosmetics using Citrus Aurantium Bergamia Fruit Oil are removing the furanocoumarins.

Bergamot oil was also found to have anti-inflammatory, antibacterial and antifungal properties.

Learn more about Citrus Aurantium Bergamia Fruit Oil

Pelargonium Graveolens Flower Oil is the pressed oil of the Rose Geranium plant. It is volatile, meaning it evaporates off the skin.

Rose Geranium contains antimicrobial, anti-inflammatory, and antioxidant properties. It has been shown to reduce bacteria and fungus. Due to these properties, Rose Geranium may help reduce acne.

The antioxidants may help reduce the signs of aging, such as fine-lines and wrinkles.

Fragrant components of Rose Geranium include citronellol and geraniol. These may cause allergies and skin-sensitivity. We recommend speaking with a professional if you have any concerns. The scent of Rose Geranium closely resembles traditional roses.

Learn more about Pelargonium Graveolens Flower Oil
Masking, Skin Conditioning

Citrus Aurantium Dulcis Peel Oil is oil from the peel of an orange fruit.

Limonene and linalool make up the majority of oils from citrus peels. Limonene has a "citrus" fragrance. Citrus peels also contain flavonoids, which have anti-inflammatory properties.

Citrus peel is also a rich source of flavonoids. Flavonoids are natural antioxidants and help protect your skin against damage. Flavonoids are a group of compounds naturally found in vegetables and fruits.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.

Learn more about Citrus Aurantium Dulcis Peel Oil
Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Masking, Perfuming, Tonic

Lavandula Angustifolia Oil is more commonly known as lavender essential oil.

Lavender imparts a famous scent. While the smell is lovely, this ingredient and may sensitize skin in topical products. This is because it contains linalool, a known allergen.

However, lavender essential oil has shown to have anti-inflammatory activity due to its prostanoid and histamine content. Its leaves also exhibit antibacterial properties.

More research is needed to confirm lavender essential oil's effects when used in aromatherapy.

Lavandula Angustifolia is known as the English Lavender and famous for creating purple fields in Provence, France.

Learn more about Lavandula Angustifolia Oil
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Masking, Skin Conditioning

Rosmarinus Officinalis Leaf Oil is oil expressed from the leaves of the rosemary plant.

Rosemary Leaf Oil is a fragrance and helps give your product a scent. If you are sensitive to irritating fragrances, this one contains camphor. Camphor has been found to irritate skin.

This oil also contains antioxidant and antimicrobial properties. As an antioxidant, it may protect you skin against damage. This can help slow down the signs of aging.

Learn more about Rosmarinus Officinalis Leaf Oil
Masking, Skin Conditioning, Tonic

Citrus Nobilis Peel Oil is an oil.

Masking, Tonic

Salvia Officinalis Oil is an oil.

This ingredient is commonly known as Patchouli oil.

Patchouli exhibits slight antibacterial and antifungal activity from its patchoulol and alpha-patchoulene content.

However, it also contains known skin-irritating fragrances. A study from 2015 found limonene and camphor as active components of this ingredient.

Limonene and camphor are both known EU allergens.

Learn more about Pogostemon Cablin Leaf Oil
Masking, Perfuming, Tonic

Litsea Cubeba Fruit Oil is a fragrance and is an oil.

Masking, Perfuming, Skin Conditioning

This oil is created by distilling the dried flower heads of the Roman Chamomile flower.

Chamomile is rich in antioxidants and has anti-inflammatory properties. Several compounds found in chamomile help with soothing, such as bisbolol.

Emollient, Emulsifying, Emulsion Stabilising

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.

Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.

Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.

Learn more about Cetearyl Alcohol

Pentaerythrityl Tetraethylhexanoate is an emollient that helps make your skin smooth and hydrated. It specializes in creating a non-oily and "wet" feeling on skin.

This ingredient comes from isostearic acid, a saturated fatty acid. It is a synthetic ingredient.

Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Emulsifying

Octyldodeceth-16 comes from the fatty-alcohol Octyldodecanol.

Emulsifers keep oils and water ingredients together to create a more even consistency.

We don't have a description for Dipentaerythrityl Hexahydroxystearate/Hexastearate/Hexarosinate yet.

Emollient, Skin Conditioning

We don't have a description for Cholesteryl Hydroxystearate yet.

Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Buffering, Masking

Tromethamine helps balance the pH and improve the texture of a product. It is synthetically created.

As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.

Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Learn more about Tromethamine
Emollient, Emulsion Stabilising

A type of fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as traditional alcohols.

Emollients help keep your skin soft and hydrated by creating a film that traps moisture in.

Behenyl Alcohol is usually derived from the fats in vegetable oils.

In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores.

Learn more about Behenyl Alcohol
Emulsion Stabilising, Masking

Cellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.

As an emulsifier, cellulose gum specifically thicken the texture of water-based products.

This ingredient is considered hypoallergenic and non-toxic. Cellulose Gum can be found in cosmetics, food, and other household goods such as paper products.

Learn more about Cellulose Gum
Humectant, Skin Conditioning

Fructooligosaccharides is an alternative sweetener. It is often derived from the blue agave plant.

This ingredient is a prebiotic and helps to hydrate the skin. Emerging studies are also showing fructooligosaccharides to have antioxidant properties.

As a humectant, Fructooligosaccharides helps draw moisture to the skin, helping to hydrate the skin.

Bananas, onions, garlic, asparagus, jícama, and leeks also contain fructooligosaccharides.

Learn more about Fructooligosaccharides
Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Learn more about Dipropylene Glycol
Emollient, Emulsifying

Glyceryl Stearate is a mix of glycerin and stearic acid.

It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.

As an emollient, it helps soften skin and supports barrier-replenishing ingredients.

In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.

This ingredient may not be fungal-acne safe

Fun fact: The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate
Emollient, Emulsifying, Skin Conditioning

Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.

Our skin naturally contains cholesterol in the outermost layer. Besides cholesterol, it also contains ceramides and fatty acids. Cholesterol makes up about 1/4 of your skin's outer layer and barrier. Your skin barrier is responsible for keeping allergens and microbes out. Having a healthy skin barrier is also responsible for keeping your skin firm and plump.

Our bodies use cholestrol to create vitamin D, steroid hormones, and more.

Learn more about Cholesterol
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

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· Updated September 16, 2024 Added by bradley_gilbert