SkinBetter Science Trio Rebalancing Moisture Treatment Versus SkinCeuticals P-Tiox Wrinkle-Modulating Peptide Cream
This barrier-repair moisturizer is formulated around Cholesterol and Squalane to strengthen the skin barrier and hydrate skin.
This anti-aging moisturizer is formulated around Niacinamide and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingGlyceryl Stearate
EmollientCholesterol
EmollientGlycerin
HumectantHydroxyethyl Urea
HumectantButylene Glycol
HumectantSodium Lactate
BufferingPolyglyceryl-6 Palmitate/Succinate
EmulsifyingSodium PCA
HumectantSqualane
EmollientIsocetyl Stearoyl Stearate
EmollientEthyl Macadamiate
Skin ConditioningN-Capryloyl Lysine
EmollientJojoba Esters
EmollientCarnitine
CleansingDimethicone
EmollientSodium Hyaluronate
HumectantUrea
BufferingAminopropyl Ascorbyl Phosphate
AntioxidantSalicornia Herbacea Extract
Skin ConditioningCeramide EOP
Skin ConditioningCeramide NP
Skin ConditioningLinoleic Acid
CleansingLinolenic Acid
CleansingCarnosine
Skin ConditioningCaffeine
Skin ConditioningSalicylic Acid
MaskingTocopherol
AntioxidantPullulan
Caprylyl Methicone
Skin ConditioningSclerotium Gum
Emulsion StabilisingXanthan Gum
EmulsifyingCetearyl Alcohol
EmollientEthylhexylglycerin
Skin ConditioningTriethyl Citrate
MaskingSilica
AbrasiveLecithin
EmollientPhytic Acid
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantTriacetin
AntimicrobialSodium Hydroxide
BufferingPhenoxyethanol
PreservativeLactic Acid
BufferingWater, Caprylic/Capric Triglyceride, Glyceryl Stearate, Cholesterol, Glycerin, Hydroxyethyl Urea, Butylene Glycol, Sodium Lactate, Polyglyceryl-6 Palmitate/Succinate, Sodium PCA, Squalane, Isocetyl Stearoyl Stearate, Ethyl Macadamiate, N-Capryloyl Lysine, Jojoba Esters, Carnitine, Dimethicone, Sodium Hyaluronate, Urea, Aminopropyl Ascorbyl Phosphate, Salicornia Herbacea Extract, Ceramide EOP, Ceramide NP, Linoleic Acid, Linolenic Acid, Carnosine, Caffeine, Salicylic Acid, Tocopherol, Pullulan, Caprylyl Methicone, Sclerotium Gum, Xanthan Gum, Cetearyl Alcohol, Ethylhexylglycerin, Triethyl Citrate, Silica, Lecithin, Phytic Acid, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Triacetin, Sodium Hydroxide, Phenoxyethanol, Lactic Acid
Water
Skin ConditioningButylene Glycol
HumectantNiacinamide
SmoothingGlycerin
HumectantDicaprylyl Carbonate
EmollientPentylene Glycol
Skin ConditioningCetearyl Alcohol
Emollient1,2-Hexanediol
Skin ConditioningIsododecane
EmollientC14-22 Alcohols
Emulsion StabilisingCaprylic/Capric Triglyceride
MaskingVinyldimethicone
Macadamia Integrifolia Seed Oil
Skin ConditioningGlyceryl Stearate Se
EmulsifyingC12-20 Alkyl Glucoside
EmulsifyingNymphaea Alba Flower Extract
Skin ConditioningAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingButyrospermum Parkii Butter
Skin ConditioningC12-16 Alcohols
EmollientTromethamine
BufferingPsidium Guajava Fruit Extract
AstringentCamellia Sinensis Leaf Extract
AntimicrobialAllium Sativum Bulb Extract
Skin ConditioningZinc PCA
HumectantCapryloyl Salicylic Acid
ExfoliatingPsidium Guajava Leaf Extract
AstringentLuffa Cylindrica Fruit Extract
Skin ConditioningHydrogenated Lecithin
EmulsifyingPalmitic Acid
EmollientCetyl Palmitate
EmollientEthylhexylglycerin
Skin ConditioningAdenosine
Skin ConditioningSorbitan Stearate
EmulsifyingPolysorbate 80
EmulsifyingTocopherol
AntioxidantCeramide NP
Skin ConditioningDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin ConditioningSodium Benzoate
MaskingCitric Acid
BufferingPalmitoyl Tetrapeptide-10
Skin ConditioningWater, Butylene Glycol, Niacinamide, Glycerin, Dicaprylyl Carbonate, Pentylene Glycol, Cetearyl Alcohol, 1,2-Hexanediol, Isododecane, C14-22 Alcohols, Caprylic/Capric Triglyceride, Vinyldimethicone, Macadamia Integrifolia Seed Oil, Glyceryl Stearate Se, C12-20 Alkyl Glucoside, Nymphaea Alba Flower Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butyrospermum Parkii Butter, C12-16 Alcohols, Tromethamine, Psidium Guajava Fruit Extract, Camellia Sinensis Leaf Extract, Allium Sativum Bulb Extract, Zinc PCA, Capryloyl Salicylic Acid, Psidium Guajava Leaf Extract, Luffa Cylindrica Fruit Extract, Hydrogenated Lecithin, Palmitic Acid, Cetyl Palmitate, Ethylhexylglycerin, Adenosine, Sorbitan Stearate, Polysorbate 80, Tocopherol, Ceramide NP, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Benzoate, Citric Acid, Palmitoyl Tetrapeptide-10
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPCetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Learn more about Cetearyl AlcoholEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water