Sesderma Mandelac Liposomal Serum Versus Sesderma Mandelac Moisturizing Cream
Updated on April 04, 2025
Overview
What they are
These products are both cruelty-free . They have a total of 26 ingredients in common
Cool Features
They both contain AHA
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any sulfates
What's Inside
They both contain harsh alcohols, common allergens, fragrances, parabens and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Sesderma Mandelac Liposomal Serum 37 ingredients
Sesderma Mandelac Moisturizing Cream 57 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
Sesderma Mandelac Liposomal Serum 37 ingredients
Sesderma Mandelac Moisturizing Cream 57 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Alcohol comes in many different forms. Different types of alcohol will have different effects on skin. This ingredient is usually an astringent alcohol.
These alcohols are drying on the skin. They may strip away your skin's natural oils and even damage your skin barrier. Astringent alcohols may also irritate skin.
Other types of astringent alcohols include:
According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.
Any type of sanitizing product will have high amounts of alcohol to help kill bacteria and viruses.
Fatty alcohols come from plant oils such as coconut oil. These can help hydrate the skin and are non-irritating. Some fatty alcohols include cetyl and stearyl alcohol.
Learn more about AlcoholAmmonium Acryloyldimethyltaurate/Vp Copolymer (let's call it AAVC for short) is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
AAVC is able to increase the consistency and viscosity of products due to its large molecule size. It also prevents ingredients from separating.
C12-15 Alkyl Benzoate is made up of Benzoic Acid and long chain alcohols. It has a low molecular weight.
C12-15 Alkyl Benzoate is an emollient and texture enhancer. Due to its solubility, it is often used in sunscreens to help evenly distribute active ingredients.
As an emollient, C12-15 Alkyl Benzoate helps soften and hydrate your skin. Emollients create a film on your skin that traps moisture within.
This ingredient has been reported to cause eye irritation.
Learn more about C12-15 Alkyl BenzoateCitral is a fragrance and used to add a lemon-like scent to products. It is both naturally found in plants and created synthetically. In plants, it is commonly occurring in lemon myrtle, lemongrass, lemon tea-tree, lemon verbena, and other citruses.
The EU mandates Citral be listed separately as a fragrance. It is a known allergen and may cause contact dermatitis. Citral can also used as a masking ingredient.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
The term 'citral' is a collective term for two geometric isomers: geranial/Citral A and neral/Citral B.
Learn more about CitralCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidCoumarins are a group of substances found naturally in plants. There are over 1300 types of coumarins identified. It has a natural vanilla scent.
Coumarin is an identified EU known allergy, meaning it may cause an allergic reaction when applied to the skin.
In many countries, coumarin is banned as a food additive. However, it can be found in soaps, tobacco products, and some alcohol drinks.
Plants use coumarins as a chemical defense. Some plants that have coumarins include lavender, tonka beans, and yellow clovers.
Learn more about CoumarinDimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeEthylparaben is a preservative, is a paraben, and is not reef safe.
Eugenol is naturally found in cloves, basil, and bay leaves. It is an aromatic oil used to add fragrance to a product. The scent of eugenol is described as "clove-like". Eugenol is a known EU allergen, meaning it causes contact allergies.
Studies show eugenol possesses antibacterial and antioxidant properties.
Besides cosmetics, eugenol is also added as a flavor in teas and cakes.
Learn more about EugenolGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate is a mix of glycerin and stearic acid.
It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.
As an emollient, it helps soften skin and supports barrier-replenishing ingredients.
In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.
This ingredient may not be fungal-acne safe
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateGlycolic Acid is arguably the most famous alpha hydroxy acid (AHA) with tons of research backing its benefits.
It is found naturally in sugar cane but the form used in skincare is usually synthetic for purity and stability.
Glycolic acid removes the top layer of dead skin cells to allow newer and fresher ones to emerge.
AHAs work by breaking down the structural “glue” that holds old skin cells in place. When that buildup is gone, your skin can renew itself more efficiently.
Research also shows glycolic acid stimulates collagen production, helping to firm and thicken the skin over time. This is one of its biggest advantages over other AHAs.
Overall, glycolic acid helps with:
Fun fact: Glycolic acid boosts skin hydration by helping it produce molecules that increase hyaluronic acid naturally.
To work best, glycolic acid products should have a pH between 3-4 (that’s where exfoliation is most effective but still gentle on skin).
The pH and concentration of a product are key to its effectiveness:
It is normal to feel a slight stinging sensation when using glycolic acid. This usually fades as your skin adjusts.
Because glycolic acid has the smallest molecular size in the AHA family, it can penetrate deeper, which enhances its effectiveness but also makes it more likely to irritate sensitive skin.
If your skin is very sensitive or prone to rosacea, glycolic acid may be too strong; in that case, try milder options like lactic acid or a PHA instead.
Recent studies suggest glycolic acid might even help protect against UV damage. But don’t skip sunscreen! Freshly exfoliated skin is more sensitive to the sun.
Glycolic acid is a skincare superstar. It smooths, brightens, hydrates, and firms the skin. Unless you’re highly sensitive, it’s well worth adding to your routine.
Read more about some other popular AHA's here:
Learn more about Glycolic AcidIsoeugenol is a fragrance component that is naturally occurring in plants such as ylang-ylang, nutmeg, and cinnamon.
Isoeugenol is a known EU allergen. This means it is known to cause an allergic reaction when applied to the skin.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Some other names for this ingredient include soy lecithin and deoiled soy lecithin.
Learn more about LecithinLimonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimoneneThis ingredient comes from a rare Swiss apple known as Uttwiler Spätlauber. It is produced from the cell cultures of the apple and not the fruit itself.
According to manufacturer studies, this ingredient has demonstrated the following benefits:
- Visible anti-wrinkle effect around the eye area (in vivo)
- Enhanced colony-forming efficiency of epidermal stem cells (in vitro)
- Improved ability of skin cells to regenerate and build new tissues in a 3D epidermis model (in vitro)
- Increased skin density (in vitro)
- Boosted vitality of epidermal stem cells (in vitro)
- Reversal of cellular aging signs in fibroblasts (in vitro)
Mandelic Acid is an alpha hydroxy acid (AHA).
Like other AHAs, it helps exfoliate the surface of the skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
Mandelic acid helps with:
Due to it having a larger molecular size than glycolic acid, mandelic acid is able to penetrate the skin more slowly and evenly. This makes it gentler and less irritating, making it a great option for sensitive or beginner skin.
Despite being milder, mandelic acid is still an effective exfoliant that improves skin texture and tone over time.
What makes mandelic acid stand out from other AHAs? It has antibacterial and antioxidant properties.
These traits make it a great option for acne-prone or problem skin by reducing active breakouts and fading post-acne marks. Studies show that mandelic acid (especially when combined with salicylic acid) can significantly reduce pimples and hyperpigmentation while causing fewer side effects than stronger acids.
Mandelic acid is effective in concentrations of 5% and up with an ideal pH range of 3-4 for at-home use.
Like other AHAs, it’s important to wear sunscreen daily to protect your newly exfoliated skin.
However, unlike glycolic acid, mandelic acid is light-sensitive. Be sure your mandelic acid is packaged in opaque containers to ensure it stays stable and effective.
In short, mandelic acid is a gentle yet powerful AHA that exfoliates, brightens, and helps clarify skin while keeping irritation low. Its antibacterial action makes it especially beneficial for those with acne-prone, sensitive, or uneven skin, offering smoother, clearer, and more even-toned results over time.
Read more about some other popular AHA's here:
Learn more about Mandelic AcidMethylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.
Methylparaben can be synthetically created. It can also be found naturally in some fruits, such as blueberries.
Oftentimes, Methylparaben is combined with other parabens to help increase the shelf life.
The safety of Methylparaben is currently being studied. While ongoing studies are looking into the safety of parabens, the results have been very mixed. Some studies have not found Methylparaben to be harmful.
Learn more about MethylparabenParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.
This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.
Those with sensitive skin or conditions may develop a rash when using this ingredient.
Learn more about Propylene GlycolPropylparaben is a preservative and is a paraben with antifungal and antimicrobial properties.
This ingredient can be naturally found in plants and insects, but most of it is synthetically manufactured for human use. In cosmetics, it is usually created by reacting para-aminobenzoic acid and propanol (an alcohol).
You can usually find this ingredient in water-based products.
Parabens have come under controversy due to the claim they are hormone disruptors. Studies show conflicting results. We recommend speaking with a professional if you have any concerns.
Propylparaben is commonly found in food, medicine, and cosmetics.
Learn more about PropylparabenSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
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Sesderma Mandelac Liposomal Serum 37 ingredients
Sesderma Mandelac Moisturizing Cream 57 ingredients
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