Remedy For Aging Versus Dermwel Daily Dose
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningPropanediol
SolventGlyceryl Stearate
EmollientNiacinamide
SmoothingGlycerin
HumectantGlycolic Acid
BufferingLactic Acid
BufferingCetearyl Alcohol
EmollientRetinol
Skin ConditioningPhospholipids
Skin ConditioningCaprylic/Capric Triglyceride
MaskingRetinal
Skin ConditioningCellulose
AbsorbentAcetyl Hexapeptide-8
HumectantSqualane
EmollientPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningDicaprylyl Carbonate
EmollientSodium Hydroxide
BufferingSimmondsia Chinensis Seed Oil
EmollientSodium Magnesium Silicate
Ceramide NP
Skin ConditioningPichia/Resveratrol Ferment Extract
Skin ConditioningGluconolactone
Skin ConditioningFerulic Acid
AntimicrobialCentella Asiatica Meristem Cell Culture
AntioxidantUbiquinone
AntioxidantAcacia Senegal Gum
MaskingXanthan Gum
EmulsifyingSodium Phytate
Tocopherol
AntioxidantSodium Benzoate
MaskingSodium Hyaluronate
HumectantButylene Glycol
HumectantCamellia Sinensis Leaf Extract
AntimicrobialCurcuma Longa Root Extract
MaskingPolysorbate 20
EmulsifyingCitric Acid
BufferingPotassium Sorbate
PreservativeCarbomer
Emulsion StabilisingPhenoxyethanol
PreservativeWater, Propanediol, Glyceryl Stearate, Niacinamide, Glycerin, Glycolic Acid, Lactic Acid, Cetearyl Alcohol, Retinol, Phospholipids, Caprylic/Capric Triglyceride, Retinal, Cellulose, Acetyl Hexapeptide-8, Squalane, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Dicaprylyl Carbonate, Sodium Hydroxide, Simmondsia Chinensis Seed Oil, Sodium Magnesium Silicate, Ceramide NP, Pichia/Resveratrol Ferment Extract, Gluconolactone, Ferulic Acid, Centella Asiatica Meristem Cell Culture, Ubiquinone, Acacia Senegal Gum, Xanthan Gum, Sodium Phytate, Tocopherol, Sodium Benzoate, Sodium Hyaluronate, Butylene Glycol, Camellia Sinensis Leaf Extract, Curcuma Longa Root Extract, Polysorbate 20, Citric Acid, Potassium Sorbate, Carbomer, Phenoxyethanol
Water
Skin ConditioningGlycerin
HumectantPropanediol
SolventGluconolactone
Skin ConditioningSqualane
EmollientMandelic Acid
AntimicrobialIsopentyldiol
HumectantAmmonium Acryloyldimethyltaurate/Vp Copolymer
Sodium Hydroxide
BufferingUndecane
EmollientAscorbyl Glucoside
AntioxidantAllantoin
Skin ConditioningSalicylic Acid
MaskingAvena Sativa Kernel Flour
AbrasivePolylysine
Hydrolyzed Pea Protein
EmollientSodium Hyaluronate
HumectantTremella Fuciformis Sporocarp Extract
AntioxidantTrifolium Pratense Flower Extract
AstringentSodium Citrate
BufferingCaprylhydroxamic Acid
Isostearamidopropyl Dimethylamine
Isostearamidopropyl Ethyldimonium Ethosulfate
Isostearic Acid
CleansingGlucose
Humectant1,2-Hexanediol
Skin ConditioningTridecane
PerfumingPEG-8
HumectantCitric Acid
BufferingCarnosine
Skin ConditioningPanthenol
Skin ConditioningDiglucosyl Gallic Acid
Lactic Acid
BufferingSalix Nigra Bark Extract
Skin ProtectingPropylene Glycol
HumectantCarthamus Tinctorius Seed Oil
MaskingOlea Europaea Fruit Oil
MaskingSodium Chloride
MaskingSodium Succinate
BufferingTocopherol
AntioxidantWater, Glycerin, Propanediol, Gluconolactone, Squalane, Mandelic Acid, Isopentyldiol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sodium Hydroxide, Undecane, Ascorbyl Glucoside, Allantoin, Salicylic Acid, Avena Sativa Kernel Flour, Polylysine, Hydrolyzed Pea Protein, Sodium Hyaluronate, Tremella Fuciformis Sporocarp Extract, Trifolium Pratense Flower Extract, Sodium Citrate, Caprylhydroxamic Acid, Isostearamidopropyl Dimethylamine, Isostearamidopropyl Ethyldimonium Ethosulfate, Isostearic Acid, Glucose, 1,2-Hexanediol, Tridecane, PEG-8, Citric Acid, Carnosine, Panthenol, Diglucosyl Gallic Acid, Lactic Acid, Salix Nigra Bark Extract, Propylene Glycol, Carthamus Tinctorius Seed Oil, Olea Europaea Fruit Oil, Sodium Chloride, Sodium Succinate, Tocopherol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidGluconolactone is a PHA. PHAs are a great gentle alternative to traditional AHAs.
When applied, Gluconolactone has the same affect on skin as AHAs such as lactic acid. It helps dissolve the dead skin cells in the top layer of your skin. This improves texture and brightens the skin.
PHAs are more gentle than AHAs due to their larger structure. They do not penetrate as deeply as AHAs and take a longer time to dissolve dead cells. Studies show PHAs do not cause as much irritation.
Gluconolactone has some interesting properties:
In a 2004 study, Gluconolactone was found to prevent UV damage in mouse skin cells and has not been found to increase sun sensitivity. However, we still recommend wearing SPF daily.
This ingredient is is an created by reacting gluconic acid with an alcohol.
Learn more about GluconolactoneGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the âglueâ that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they donât penetrate as deeply. This means theyâre less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skinâs microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the productâs pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.Â
Itâs often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideSqualane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, itâs technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term âoil-freeâ isnât regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water