Versus

Drunk Elephant Protini Polypeptide Cream - US Versus Acure Radically Rejuvenating Whipped Night Cream

General Moisturizer
Night Moisturizer
American Brand United States
American Brand United States

Updated on July 25, 2025

Overview

What they are

These products are both vegan, cruelty-free, and reef safe . They have a total of 35 ingredients in common

Cool Features

They both contain hyaluronic acid and peptides

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates

What's Inside

They both contain fragrances and oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Protini Polypeptide Cream

Water

Skin Conditioning

Dicaprylyl Carbonate

Emollient

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Cetearyl Olivate

Not safe for Fungal Acne Icon

Sorbitan Olivate

Emulsifying
Not safe for Fungal Acne Icon

Sclerocarya Birrea Seed Oil

Humectant
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Bacillus/Folic Acid Ferment Filtrate Extract

Antioxidant
Antioxidant Icon

Nymphaea Alba Root Extract

Skin Conditioning

Sh-Oligopeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging IconGood for Scar Healing Icon

Sh-Oligopeptide-2

Skin Conditioning
Peptide Icon

Sh-Polypeptide-1

Skin Conditioning
Peptide Icon

Sh-Polypeptide-9

Skin Conditioning
Peptide Icon

Sh-Polypeptide-11

Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Copper Palmitoyl Heptapeptide-14

Skin Conditioning
Peptide Icon

Heptapeptide-15 Palmitate

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Alanine

Masking

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Glycine

Buffering
Helps hydrate Dry Skin Icon

Histidine

Humectant
Helps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Isoleucine

Skin Conditioning

Phenylalanine

Masking
Helps hydrate Dry Skin IconGood for Scar Healing Icon

Proline

Skin Conditioning

Serine

Masking
Helps hydrate Dry Skin Icon

Threonine

Helps hydrate Dry Skin Icon

Valine

Masking

Acetyl Glutamine

Skin Conditioning

Coconut Alkanes

Emollient
Not safe for Fungal Acne Icon

Coco-Caprylate/Caprate

Emollient
Not safe for Fungal Acne Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Aspartic Acid

Masking
Helps hydrate Dry Skin Icon

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Linolenic Acid

Cleansing
Fragrance IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconNot safe for Fungal Acne Icon

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Polyvinyl Alcohol

Sodium Lactate

Buffering

Sodium PCA

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

PCA

Humectant
Helps hydrate Dry Skin Icon

Sorbitan Isostearate

Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon

Carbomer

Emulsion Stabilising
1 / 0

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Polysorbate 60

Emulsifying
Not safe for Fungal Acne Icon

Lactic Acid/Glycolic Acid Copolymer

Skin Conditioning

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Xanthan Gum

Emulsifying

Isomalt

Humectant

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Chlorphenesin

Antimicrobial
Preservative Icon

Phenoxyethanol

Preservative
Preservative Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Sodium Benzoate

Masking
Preservative Icon

Phenylpropanol

Masking
Fragrance Icon

Glyceryl Caprylate

Emollient

Symphytum Officinale Callus Culture Extract

Skin Conditioning
Radically Rejuvenating Whipped Night Cream

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Skin Conditioning

We don't have a description for Acetyl Glutamine yet.

Antioxidant, Humectant, Skin Conditioning

Bacillus/Folic Acid Ferment Filtrate Extract is an antioxidant.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Emollient, Emulsifying, Emulsion Stabilising

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.

Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.

Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.

Learn more about Cetearyl Alcohol

Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.

As an emulsifier, it is used to prevent oils and waters from separating. It can also

Manufacturers use the name Olivem 1000. This ingredient has been found to preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria. This ingredient is grouped with Sorbitan Olivate under the name Olivem 1000.

Learn more about Cetearyl Olivate
Emollient, Skin Conditioning

Coco-Caprylate/Caprate is created from fatty coconut alcohol, caprylic acid, and capric acid.

It is a lightweight emollient. Emollients create a thin barrier on the skin to trap moisture in. This helps keep your skin hydrated and soft.

Once applied, Coco-Caprylate/Caprate is absorbed quickly and leaves a silky feel.

Coco-Caprylate/Caprate may not be fungal acne safe.

Learn more about Coco-Caprylate/Caprate
Emollient, Solvent

Coconut Alkanes is created from the fatty-acids of coconut oil. It is volatile, meaning it evaporates from the skin.

This ingredient is an emollient and solvent. As an emollient, it helps keep skin soft and hydrated. Solvents help distribute and mix other ingredients. This ensures a more even consistency.

Coconut Alkanes may not be fungal-acne safe.

Learn more about Coconut Alkanes

This peptide is the copper salt and formed by reacting palmitic acid and heptapeptide-14.

This uses a high-tech delivery system called The Cosmetic Drone, where the peptide is enclosed in a shell made from Lactic Acid/Glycolic Acid Copolymer and Polyvinyl Alcohol. Another peptide on the outside guides the capsule to fibroblast cells, the collagen-producing cells in the skin.

Once it reaches the fibroblasts, Copper Palmitoyl Heptapeptide-14 boosts the production of collagen and elastin.

This advanced system works at an incredibly low concentration of just 0.001%.

Learn more about Copper Palmitoyl Heptapeptide-14
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Emulsifying

Glyceryl Caprylate comes from glycerin and caprylic acid, a fatty acid from coconut. It has emollient and emulsifier properties.

As an emollient, it helps hydrate your skin. Emollients work by creating a barrier on your skin to trap moisture in, helping to keep your skin soft and smooth.

On the other hand, emulsifiers prevent ingredients (such as oil and water) from separating.

Learn more about Glyceryl Caprylate
Skin Conditioning

Heptapeptide-15 Palmitate isn't fungal acne safe and is a peptide.

Humectant

We don't have a description for Isomalt yet.

This ingredient is a combination of two AHAs, lactic acid and glycolic acid. It has exfoliating properties

Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.

This ingredient has emollient and emulsifying properties.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Some other names for this ingredient include soy lecithin and deoiled soy lecithin.

Learn more about Lecithin
Cleansing, Emollient, Skin Conditioning

Linoleic Acid is also known as Vitamin F. It is a fatty acid with emollient and skin conditioning properties. Our top layer of skin, or epidermis, contains high amounts of linoleic acid naturally.

Your body uses linoleic acid to build ceramides and prostaglandins. Ceramides keep your skin's barrier hydrated and strong while prosaglandins help control inflammation and healing. Needless to say, linoleic acid is crucial for having a strong skin barrier.

One study found applying linoleic acid rich sunflower oil to be more effective at repairing the skin barrier than oleic rich olive oil.

Linoleic acid is an essential fatty acid, meaning our bodies cannot create it on its own. We need to get linoleic acid through foods such as nuts and vegetable oils.

Acne-prone skin tends to have linoleic acid and high levels of oleic acid.

Linoleic acid can also help treat acne by softening sebum to prevent clogged pores. Another study found using 2.5% linoleic acid gel for 4 weeks showed a 25% reduction in small comedones.

This ingredient can also help lighten hyperpigmentation or sun spots by disrupting the melanin production process. It also helps your skin shed melanin pigment from your skin caused by UV exposure.

Due to its role in the production of the fatty acid prostaglandin, linoleic acid can also help reduce inflammation and support wound healing.

Linoleic acid is not always fungal-acne safe; it may trigger flare-ups in sensitive individuals.

Learn more about Linoleic Acid
Cleansing, Emollient, Perfuming

Linolenic Acid is also known as "ALA" or alpha-linolenic acid. It is a fatty acid used to hydrate skin and hair.

This ingredient can help with soothing irritated skin and reducing hyperpigmentation by disrupting the melanin production process.

Fun fact: This ingredient is considered an essential fatty acid for humans. This means our bodies cannot naturally produce it and we must get it from food.

Some foods rich in linolenic acid include: walnuts, fish oils, soy, and canola.

A deficiency in linolenic acid may be linked to skin disorders like eczema.

Another essential fatty acid is Linoleic Acid.

Learn more about Linolenic Acid
Skin Conditioning

Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).

This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.

Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.

Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.

Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. It’s commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).

Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tetrapeptide-7
Skin Conditioning

Palmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.

This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.

By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.

You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.

Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tripeptide-1
Emulsifying

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20

We don't have a description for Polyvinyl Alcohol yet.

Sclerocarya Birrea Seed Oil is the oil expressed from the seeds of the Marula plant. In South Africa, Marula is called "an elephant's favorite treat".

Marula seed oil is a non-fragrant oil. It is rich in fatty acids, such as oleic, linoleic, palmitic, stearic, and more. These fatty acids help hydrate the skin.

Other components of marula seed oil include vitamin E and antioxidants such as flavonoids.

Due to the fatty acid content, this ingredient may not be fungal-acne safe.

Learn more about Sclerocarya Birrea Seed Oil
Skin Conditioning

sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.

In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.

Studies find EGF help with:

In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.

According to Dr. Zoe Draelos, growth factors have some drawbacks:

There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.

Learn more about Sh-Oligopeptide-1
Skin Conditioning, Skin Protecting

This peptide has similar properties to Sh-Oligopeptide-1.

In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.

There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.

Learn more about Sh-Oligopeptide-2
Skin Conditioning

Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.

It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.

Sh-Polypeptide-11 is a signal protein that tells our skin to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.

It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.

Skin Conditioning

Sh-Polypeptide-9 is a signal peptide that tells our body to create more blood vessels.

It is important to note, this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.

Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Humectant, Skin Conditioning

Sodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.

The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.

This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.

Learn more about Sodium PCA
Emulsifying

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

As an emulsifier, Sorbitan Isostearate prevents oils and water from separating.

Due to its isostearic acid base, it may not be safe for Malassezia or fungal acne.

Learn more about Sorbitan Isostearate
Emulsifying

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.

Manufacturers sell sorbitan olivate under the name OliveM 1000. OliveM 1000 a multifunctional ingredient. It is self-emulsifying. According to a manufacturer, OliveM 1000 does not disrupt natural skin biome.

Due to its olive oil base, this ingredient may not be fungal-acne safe.

Learn more about Sorbitan Olivate
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

When to use

708 Routines
51% use in am
49% use in pm
94% use every day
When to use See routines that use it ->
46 Routines
26% use in am
74% use in pm
93% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

3.60
Overall rating
5
4
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What people say
Expensive 67% Hydrating 50% Absorbs Well 33%
4.00
Overall rating
5
4
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What people say
Works Well 67% Hydrating 67% No Scent 67%