Drunk Elephant Protini Polypeptide Cream - US Versus Acure Radically Rejuvenating Whipped Night Cream
Updated on March 19, 2025
Overview
What they are
These products are both vegan, cruelty-free, and reef safe . They have a total of 27 ingredients in common
Cool Features
They both contain hyaluronic acid and peptides
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin and scar healing
Free From
They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates
What's Inside
They both contain fragrances and oils
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Drunk Elephant Protini Polypeptide Cream 58 ingredients
Acure Radically Rejuvenating Whipped Night Cream 31 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Drunk Elephant Protini Polypeptide Cream 58 ingredients
Acure Radically Rejuvenating Whipped Night Cream 31 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.
Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.
Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.
Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.
Learn more about Cetearyl AlcoholCetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.
As an emulsifier, it is used to prevent oils and waters from separating. It can also
Manufacturers use the name Olivem 1000. This ingredient has been found to preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria. This ingredient is grouped with Sorbitan Olivate under the name Olivem 1000.
Learn more about Cetearyl OlivateSorbitan Olivate is created from the fatty acids in olive oil and sorbitol.
This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.
Manufacturers sell sorbitan olivate under the name OliveM 1000. OliveM 1000 a multifunctional ingredient. It is self-emulsifying. According to a manufacturer, OliveM 1000 does not disrupt natural skin biome.
Due to its olive oil base, this ingredient may not be fungal-acne safe.
Learn more about Sorbitan OlivateSclerocarya Birrea Seed Oil is the oil expressed from the seeds of the Marula plant. In South Africa, Marula is called "an elephant's favorite treat".
Marula seed oil is a non-fragrant oil. It is rich in fatty acids, such as oleic, linoleic, palmitic, stearic, and more. These fatty acids help hydrate the skin.
Other components of marula seed oil include vitamin E and antioxidants such as flavonoids.
Due to the fatty acid content, this ingredient may not be fungal-acne safe.
Learn more about Sclerocarya Birrea Seed OilWe don't have a description for Nymphaea Alba Root Extract yet.
sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-1This peptide has similar properties to Sh-Oligopeptide-1.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-2Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Sh-Polypeptide-9 is a signal peptide that tells our body to create more blood vessels.
It is important to note, this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Sh-Polypeptide-11 is a signal protein that tells our skin to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
This peptide is the copper salt and formed by reacting palmitic acid and heptapeptide-14.
This uses a high-tech delivery system called The Cosmetic Drone, where the peptide is enclosed in a shell made from Lactic Acid/Glycolic Acid Copolymer and Polyvinyl Alcohol. Another peptide on the outside guides the capsule to fibroblast cells, the collagen-producing cells in the skin.
Once it reaches the fibroblasts, Copper Palmitoyl Heptapeptide-14 boosts the production of collagen and elastin.
This advanced system works at an incredibly low concentration of just 0.001%.
Learn more about Copper Palmitoyl Heptapeptide-14Heptapeptide-15 Palmitate isn't fungal acne safe and is a peptide.
Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
This ingredient consists of four amino acids and palmitic acid. These amino acids are arginine, proline, glutamine, and glycine.
This ingredient has many benefits. These benefits include boosting collagen production, fighting inflammation, and reversing UV damage.
By preventing our bodies from producing interleukins, Palmitoyl Tetrapeptide-7 helps fight inflammation. An interleukin is a chemical that signals to the body to produce an inflammatory response. Interleukin production is accelerated by UV radiation.
Palmitoyl Tetrapeptide-7 tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.
This ingredient is a signal peptide, meaning it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Coconut Alkanes is created from the fatty-acids of coconut oil. It is volatile, meaning it evaporates from the skin.
This ingredient is an emollient and solvent. As an emollient, it helps keep skin soft and hydrated. Solvents help distribute and mix other ingredients. This ensures a more even consistency.
Coconut Alkanes may not be fungal-acne safe.
Learn more about Coconut AlkanesSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateAspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
Linoleic Acid is Vitamin F and a fatty acid. It is an emollient and helps thicken texture. Linoleic acid helps with hydrating skin and nourishing the skin's barrier. The top layer of skin, or epidermis, contains high amounts of linoleic acid naturally.
Your body uses linoleic acid to build ceramides and prostaglandins. Ceramides keep your skin's barrier plump and firm. Prosaglandins help control inflammation and healing.
This makes linoleic acid effectives for reducing inflammation, hydrating skin, and firming skin. A side effect may include extra protection against UV damage and free radicals. This is due to linoleic acid strengthening the skin barrier.
Low levels of linoleic acid is also associated with acne-prone skin. By keeping sebum soft, it prevents pores from clogging.
Linoleic acid can is in common foods such as nuts, sunflower oil, corn oil, and soybean oil.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe.
Learn more about Linoleic AcidLinolenic Acid is a fatty acid. Linolenic Acid helps condition and restore skin.
It is also used to treat inflammation and hyperpigmentation. It works to reduce hyperpigmentation by disrupting melanin production.
You can find this ingredient in many oils, include argan, rosehip, and hemp seed.
Read about Linoleic Acid
Learn more about Linolenic AcidLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinSodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.
The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.
This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.
Learn more about Sodium PCAPCA is derived from amino acids and is naturally found in our skin's barrier.
As a humectant, PCA helps draw and hold moisture to the skin. Studies show it is effective at helping the skin stay hydrated long-term.
Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.
As an emulsifier, Sorbitan Isostearate prevents oils and water from separating.
Due to its isostearic acid base, it may not be safe for Malassezia or fungal acne.
Learn more about Sorbitan IsostearateThis ingredient is a combination of two AHAs, lactic acid and glycolic acid. It has exfoliating properties
We don't have a description for Symphytum Officinale Callus Culture Extract yet.
Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Drunk Elephant Protini Polypeptide Cream 58 ingredients
Acure Radically Rejuvenating Whipped Night Cream 31 ingredients


Reviews
Here's what our community thinks
Drunk Elephant Protini Polypeptide Cream 58 ingredients
for the price point of this moisturizer i feel like i expected a lot more?
i mostly used this moisturizer at night paired with my tretinoin and i found that the 2 worked well with each other. it’s a really nice almost gel-like cream texture with a light fragrance. i found it a little hard to blend while my face was still damp which is when i usually apply moisturizer. i don’t feel like it did Show more
My HG facial moisturizer. It makes my face feel so soft and velvety. It dries quickly, is gentle even when my face is on fire and it has a slight "chemical" smell that I tend to like. I love the pump as well. I use this when I need a good hit of luxury.
Acure Radically Rejuvenating Whipped Night Cream 31 ingredients
I use this as my daily moisturizer and love that it is packed with peptides and growth factors. The research is still not solid on those particular ingredients - other than that they are hydrating - but the price point on this product and how good it feels on my skin makes it feel like a worthwhile experiment. It takes a few minutes to soak in but once it does, it looks and feels good.
I'm hooked on the texture of this cream - rich, but not heavy, feels great on the skin. Edit: after using this up, I've decided it's maybe just a little too rich for my skin. Still love it, but only for when my skin feels really dry.