Cetaphil Healthy Renew Purified Peptides Face Serum Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Moisturizer
This anti-aging serum is formulated around Panthenol and Niacinamide to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging moisturizer is formulated around Hexapeptide-11 and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
Humectant
Glycerin
Humectant
Panthenol
Skin Conditioning
1,2-Hexanediol
Skin Conditioning
Niacinamide
Smoothing
Cetyl Ethylhexanoate
EmollientHydrogenated Polydecene
EmollientAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingTromethamine
BufferingOryza Sativa Lees Extract
Skin ConditioningLeontopodium Alpinum Extract
Skin ConditioningCalcium Alginate
MaskingPropanediol
Solvent
Hydrolyzed Soy Flour
Skin ConditioningEthylhexylglycerin
Skin ConditioningAgar
MaskingAdenosine
Skin Conditioning
Trisodium Ethylenediamine Disuccinate
ChelatingSynthetic Fluorphlogopite
Caprylyl Glycol
Emollient
Iron Oxides
Citric Acid
Buffering
Sodium Benzoate
Masking
Potassium Sorbate
Preservative
Buddleja Davidii Extract
Skin ConditioningThymus Vulgaris Extract
Perfuming
Tocopherol
Antioxidant
Water, Butylene Glycol, Glycerin, Panthenol, 1,2-Hexanediol, Niacinamide, Cetyl Ethylhexanoate, Hydrogenated Polydecene, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Oryza Sativa Lees Extract, Leontopodium Alpinum Extract, Calcium Alginate, Propanediol, Hydrolyzed Soy Flour, Ethylhexylglycerin, Agar, Adenosine, Trisodium Ethylenediamine Disuccinate, Synthetic Fluorphlogopite, Caprylyl Glycol, Iron Oxides, Citric Acid, Sodium Benzoate, Potassium Sorbate, Buddleja Davidii Extract, Thymus Vulgaris Extract, Tocopherol
Water
Skin ConditioningGlycerin
Humectant
Dimethicone
Emollient
Olive Oil Decyl Esters
Glycereth-26
Humectant
Squalane
Emollient
Butylene Glycol
Humectant
Behenyl Alcohol
Emollient
Polysilicone-11
Batyl Alcohol
EmollientSimmondsia Chinensis Seed Oil
Emollient
Hexapeptide-11
Skin Conditioning
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Tripeptide-10 Citrulline
Skin Conditioning
Acetyl Hexapeptide-1
Skin Conditioning
Acetyl Tetrapeptide-11
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Palmitoyl Hexapeptide-12
Skin Conditioning
Acetyl Tetrapeptide-9
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Acetyl Tetrapeptide-2
Skin Conditioning
Acetyl Octapeptide-3
Humectant
Palmitoyl Hexapeptide-19
Skin Conditioning
Trifluoroacetyl Tripeptide-2
Skin Conditioning
Tripeptide-1
Skin Conditioning
Palmitoyl Oligopeptide
Cleansing
Palmitoyl Tripeptide-1
Skin Conditioning
Potassium Hydrolyzed Polygamma-Glutamate
Sodium Polyglutamate
HumectantSqualene
Emollient
Mica
Cosmetic ColorantSodium Hyaluronate
Humectant
Sorbic Acid
Preservative
Tocopherol
Antioxidant
Cereus Grandiflorus Flower Extract
Skin ConditioningPseudoalteromonas Ferment Extract
Humectant
Leuconostoc/Radish Root Ferment Filtrate
Antimicrobial
Magnesium Chloride
Phenoxyethanol
Preservative
Cetyl Alcohol
Emollient
Stearyl Alcohol
Emollient
Trehalose
Humectant
Glyceryl Stearate
Emollient
Silanetriol Trehalose Ether
EmollientMannitol
Humectant
Phytosterols
Skin Conditioning
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCaprylic/Capric Triglyceride
Masking
Hydrogenated Lecithin
Emulsifying
Polyglyceryl-10 Myristate
Skin Conditioning
Polysorbate 20
Emulsifying
Dimethyl Isosorbide
SolventSodium Benzoate
Masking
Potassium Sorbate
Preservative
Caprylyl Glycol
Emollient
Sodium Hydroxide
BufferingLaureth-12
EmulsifyingHydrolyzed Wheat Protein
Skin ConditioningLecithin
Emollient
Disodium Phosphate
BufferingHydrolyzed Soy Protein
Humectant
Carbomer
Emulsion StabilisingDextran
Ethylhexylglycerin
Skin ConditioningSodium Lactate
Buffering
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Skin ConditioningSodium Phosphate
BufferingXanthan Gum
EmulsifyingTriethanolamine
BufferingAcrylates Copolymer
Water, Glycerin, Dimethicone, Olive Oil Decyl Esters, Glycereth-26, Squalane, Butylene Glycol, Behenyl Alcohol, Polysilicone-11, Batyl Alcohol, Simmondsia Chinensis Seed Oil, Hexapeptide-11, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Tripeptide-10 Citrulline, Acetyl Hexapeptide-1, Acetyl Tetrapeptide-11, Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-9, Palmitoyl Tetrapeptide-7, Acetyl Tetrapeptide-2, Acetyl Octapeptide-3, Palmitoyl Hexapeptide-19, Trifluoroacetyl Tripeptide-2, Tripeptide-1, Palmitoyl Oligopeptide, Palmitoyl Tripeptide-1, Potassium Hydrolyzed Polygamma-Glutamate, Sodium Polyglutamate, Squalene, Mica, Sodium Hyaluronate, Sorbic Acid, Tocopherol, Cereus Grandiflorus Flower Extract, Pseudoalteromonas Ferment Extract, Leuconostoc/Radish Root Ferment Filtrate, Magnesium Chloride, Phenoxyethanol, Cetyl Alcohol, Stearyl Alcohol, Trehalose, Glyceryl Stearate, Silanetriol Trehalose Ether, Mannitol, Phytosterols, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Polyglyceryl-10 Myristate, Polysorbate 20, Dimethyl Isosorbide, Sodium Benzoate, Potassium Sorbate, Caprylyl Glycol, Sodium Hydroxide, Laureth-12, Hydrolyzed Wheat Protein, Lecithin, Disodium Phosphate, Hydrolyzed Soy Protein, Carbomer, Dextran, Ethylhexylglycerin, Sodium Lactate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Sodium Phosphate, Xanthan Gum, Triethanolamine, Acrylates Copolymer
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
